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About
What is Reactome ?
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Team
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Release Calendar
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Digital Preservation
Contact us
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Table of Contents
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GDP [cytosol]
Stable Identifier
R-ALL-29420
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Guanosine 5'-diphosphate, Guanosine diphosphate, GDP(3-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Active MTORC1 binds the ULK1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Active MTORC1 phosphorylates ULK1 (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1 dissociates from ULK complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Selective autophagy (Bos taurus)
Aggrephagy (Bos taurus)
Aggresome dissociates from dynein and microtubule (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
RAN stimulates fusion of nuclear envelope (NE) membranes (Bos taurus)
RAN:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
GDP [cytosol]
RAN:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 binds to microtubules (Bos taurus)
EML4 homotrimer:Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinetochore capture of astral microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to mechanical stimuli (Bos taurus)
Response of endothelial cells to shear stress (Bos taurus)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Bos taurus)
ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
ADM:CALCLR:RAMP2:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH-ephrin mediated repulsion of cells (Bos taurus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
EPHA-mediated growth cone collapse (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Bos taurus)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Bos taurus)
HRAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Formation of clathrin coated vesicle (Bos taurus)
GDP [cytosol]
Signal transduction by L1 (Bos taurus)
Activation of Rac1 by VAV2 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Activation of Cdc42 (Bos taurus)
GDP [cytosol]
CDC42:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Activation of Rac1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Semaphorin interactions (Bos taurus)
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)
GDP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Bos taurus)
Inactivation of Rho-GTP by p190RhoGAP (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by ROBO receptors (Bos taurus)
SLIT2:ROBO1 increases RHOA activity (Bos taurus)
MYO9B inactivates RHOA (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Drug ADME (Bos taurus)
Azathioprine ADME (Bos taurus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Tie2 Signaling (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Factors involved in megakaryocyte development and platelet production (Bos taurus)
Kinesins (Bos taurus)
Kinesins bind microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)
GDP [cytosol]
VAV1 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
GDP [cytosol]
VAV2 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Bos taurus)
GDP [cytosol]
VAV3 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Gi activation by P2Y purinoceptor 12 (Bos taurus)
GDP [cytosol]
Thromboxane signalling through TP receptor (Bos taurus)
G13 activation by TP receptor (Bos taurus)
GDP [cytosol]
Gq activation by TP receptor (Bos taurus)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
Thrombin-activated PARs activate G12/13 (Bos taurus)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Bos taurus)
GDP [cytosol]
Platelet homeostasis (Bos taurus)
Prostacyclin signalling through prostacyclin receptor (Bos taurus)
Gs activation by prostacyclin receptor (Bos taurus)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Disassembly of COPII coated vesicle (Bos taurus)
GDP [cytosol]
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MHC class II antigen presentation (Bos taurus)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Bos taurus)
Arf1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
Internalization of MHC II:Ii clathrin coated vesicle (Bos taurus)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Bos taurus)
GDP [cytosol]
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Rap1 signalling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Rap1 signal termination by Rap1GAPs (Bos taurus)
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Regulation of T cell activation by CD28 family (Bos taurus)
Co-stimulation by CD28 (Bos taurus)
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Cdc42 by pVav1 (Bos taurus)
GDP [cytosol]
CDC42:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Activation of Rac1 by pVav1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
Activation of RAC1 by VAV2/3 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of RAC1 by VAV (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Mitochondrial Uncoupling (Bos taurus)
UCP1 imports a proton (Bos taurus)
Purine nucleotide [cytosol]
GDP [cytosol]
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
GDP [cytosol]
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)
GLP1R binds GLP1 (Bos taurus)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R binds GLP1R agonists (Bos taurus)
GLP1R:GLP1R agonists [plasma membrane] (Bos taurus)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAP1A exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PCK1 phosphorylates OA to yield PEP (Bos taurus)
GDP [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Bos taurus)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Bos taurus)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Bos taurus)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
GDP [cytosol]
Metabolism of RNA (Bos taurus)
Nonsense-Mediated Decay (NMD) (Bos taurus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Bos taurus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SMG6 hydrolyzes mRNA with premature termination codon (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Bos taurus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Bos taurus)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Bos taurus)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Bos taurus)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
Synthesis of dolichyl-phosphate mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ARFGAPs stimulate ARF GTPase activity (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
COPII coat binds TRAPPCII and RAB1:GDP (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GDP [cytosol]
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglycylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Bos taurus)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglycyl beta tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TTLLs polyglutamylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglutamylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglutamyl microtubule protofilament [cytosol] (Bos taurus)
Polyglutamyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglutamyl beta tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Bos taurus)
Synthesis of dolichyl-phosphate mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
GDP [cytosol]
Protein ubiquitination (Bos taurus)
E3 ubiquitin ligases ubiquitinate target proteins (Bos taurus)
RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Bos taurus)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RNF152 polyubiquitinates RRAGA (Bos taurus)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB geranylgeranylation (Bos taurus)
RGGT geranylgeranylates RAB proteins (Bos taurus)
CHMs:GGC-RABs:GDP [cytosol] (Bos taurus)
GGC-RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Bos taurus)
RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RGGT:CHM binds RABs (Bos taurus)
RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Bos taurus)
RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Elongation (Bos taurus)
Regeneration of eEF1A:GTP by eEF1B activity (Bos taurus)
eEF1A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
eEF1B:GDP exchange complex [cytosol] (Bos taurus)
GDP [cytosol]
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
GTP hydrolysis and joining of the 60S ribosomal subunit (Bos taurus)
eIF5B:GTP is hydrolyzed and released (Bos taurus)
eIF5B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Recycling of eIF2:GDP (Bos taurus)
Formation of eIF2:GDP:eIF2B intermediate (Bos taurus)
eIF2:GDP [cytosol] (Bos taurus)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Bos taurus)
GDP [cytosol]
eIF2 activation (Bos taurus)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Bos taurus)
GDP [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
GABA receptor activation (Bos taurus)
GABA B receptor activation (Bos taurus)
Activation of GABAB receptors (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
ATAT acetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Anchoring of the basal body to the plasma membrane (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GDP [cytosol]
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Bos taurus)
VxPx cargo-targeting to cilium (Bos taurus)
ASAP1 stimulates GTPase activity of ARF4 (Bos taurus)
ARF4:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
GDP [cytosol]
ARF4:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3IP and RAB8A bind to the ciliary targeting complex (Bos taurus)
RAB3IP:RAB8A:GDP [cytosol] (Bos taurus)
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
HDAC6 deacetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Intraflagellar transport (Bos taurus)
Anterograde IFT (Bos taurus)
anterograde IFT trains [ciliary tip] (Bos taurus)
active kinesin-2 motors [ciliary tip] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
anterograde IFT trains [cilium] (Bos taurus)
active kinesin-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Assembly of the anterograde IFT train (Bos taurus)
active kinesin-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
anterograde IFT trains [cilium] (Bos taurus)
active kinesin-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Retrograde IFT (Bos taurus)
retrograde IFT trains [ciliary tip] (Bos taurus)
active dynein-2 motors [ciliary tip] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
retrograde IFT trains [cilium] (Bos taurus)
active dynein-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Sensory Perception (Bos taurus)
Olfactory Signaling Pathway (Bos taurus)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Bos taurus)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Bos taurus)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
Bitter compound binds bitter taste receptor (TAS2R) (Bos taurus)
TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Bos taurus)
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Bos taurus)
TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
GNAT1-GTP hydrolyses its bound GTP to GDP (Bos taurus)
GNAT1-GDP [photoreceptor disc membrane] (Bos taurus)
GDP [cytosol]
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
p75 NTR receptor-mediated signalling (Bos taurus)
Cell death signalling via NRAGE, NRIF and NADE (Bos taurus)
NRAGE signals death through JNK (Bos taurus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)
GDP [cytosol]
p75NTR regulates axonogenesis (Bos taurus)
Axonal growth inhibition (RHOA activation) (Bos taurus)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The p75NTR:NgR:MDGI binds RHOA-GDI (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Axonal growth stimulation (Bos taurus)
NGF binding to p75NTR inactivates RHOA (Bos taurus)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:NGF [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p75NTR and RHOA-GDI interact (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
MAF1 translocates to the nucleus (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Intrinsic nucleotide exchange on RAS (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS processing (Bos taurus)
mature p21 RAS binds GDP (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
MTOR signalling (Bos taurus)
AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Formation of active mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GTP loading by Rheb (Bos taurus)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Rag dimer formation (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator binds Rag dimers (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SLC38A9 binds Ragulator:Rag dimers (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1-mediated signalling (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
GEFs activate RhoA,B,C (Bos taurus)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (i) signalling events (Bos taurus)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
GDP [cytosol]
Opioid Signalling (Bos taurus)
G-protein activation (Bos taurus)
G-protein alpha subunit is inactivated (Bos taurus)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G-protein beta-gamma subunits rebind the alpha-GDP subunit (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The high affinity receptor complex binds to G-protein (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Bos taurus)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G-protein mediated events (Bos taurus)
Adenylate cyclase activating pathway (Bos taurus)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
PLC beta mediated events (Bos taurus)
Inactivation of PLC beta (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Bos taurus)
GDP [cytosol]
G alpha (q) signalling events (Bos taurus)
G alpha (q) in G (q):RGS complex is inactivated (Bos taurus)
G alpha (q):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Bos taurus)
G alpha (q):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
EGFR Transactivation by Gastrin (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
GDP [cytosol]
G alpha (s) signalling events (Bos taurus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
GDP [cytosol]
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (z) signalling events (Bos taurus)
G alpha (z) in G alpha (z):RGS complex is inactivated (Bos taurus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Bos taurus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Bos taurus)
GDP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
GDP [cytosol]
GPCR ligand binding (Bos taurus)
Class B/2 (Secretin family receptors) (Bos taurus)
Glucagon-type ligand receptors (Bos taurus)
GLP1R binds GLP1 (Bos taurus)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Hedgehog (Bos taurus)
Hedgehog 'off' state (Bos taurus)
KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
ARHGAP35 stimulates RHOA GTPase activity (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RASA1 stimulates RAS GTPase activity (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
PRKCZ recruits RAS in response to estrogen stimulation (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
GRB2 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC1 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by ERBB2 (Bos taurus)
GRB2 events in ERBB2 signaling (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by ERBB4 (Bos taurus)
SHC1 events in ERBB4 signaling (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by MET (Bos taurus)
MET activates RAS signaling (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
MET promotes cell motility (Bos taurus)
MET activates RAP1 and RAC1 (Bos taurus)
DOCK7 activates RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAPGEF1 activates RAP1 (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
ARMS-mediated activation (Bos taurus)
C3G stimulates nucleotide exchange on Rap1 (Bos taurus)
GDP [cytosol]
Rap1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Bos taurus)
Activated NTRK2 signals through FYN (Bos taurus)
NTRK2 activates RAC1 (Bos taurus)
DOCK3 activates RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by PDGF (Bos taurus)
Downstream signal transduction (Bos taurus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by SCF-KIT (Bos taurus)
Activation of RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p-VAV family:PIP3 binds RAC1:GDP (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Miro GTPase Cycle (Bos taurus)
RHOT1 GTPase cycle (Bos taurus)
RHOT1 hydrolyzes GTP (Bos taurus)
RHOT1:GDP [mitochondrial outer membrane] (Bos taurus)
GDP [cytosol]
RHOT2 GTPase cycle (Bos taurus)
RHOT2 hydrolyzes GTP (Bos taurus)
RHOT2:GDP [mitochondrial outer membrane] (Bos taurus)
GDP [cytosol]
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHO GTPases activate IQGAPs (Bos taurus)
IQGAP1 binds CLIP1 and microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHO GTPase cycle (Bos taurus)
CDC42 GTPase cycle (Bos taurus)
CDC42 GAPs stimulate CDC42 GTPase activity (Bos taurus)
CDC42:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
CDC42 GDIs block activation of CDC42 (Bos taurus)
CDC42:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
CDC42:GDP:CDC42 GDIs [cytosol] (Bos taurus)
CDC42:GDP [cytosol] (Bos taurus)
GDP [cytosol]
CDC42 GEFs activate CDC42 (Bos taurus)
GDP [cytosol]
CDC42:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC1 GTPase cycle (Bos taurus)
RAC1 GAPs stimulate RAC1 GTPase activity (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC1 GDIs block activation of RAC1 (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC1:GDP:RAC1 GDIs [cytosol] (Bos taurus)
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC1 GEFs activate RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC2 GTPase cycle (Bos taurus)
RAC2 GAPs stimulate RAC2 GTPase activity (Bos taurus)
RAC2:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC2 GDIs block activation of RAC2 (Bos taurus)
ARHGDIA:RAC2:GDP [cytosol] (Bos taurus)
RAC2:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC2 GEFs activate RAC2 (Bos taurus)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC3 GTPase cycle (Bos taurus)
RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)
RAC3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC3 GDIs block activation of RAC3 (Bos taurus)
RAC3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC3:GDP:RAC3 GDIs [cytosol] (Bos taurus)
RAC3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC3 GEFs activate RAC3 (Bos taurus)
GDP [cytosol]
RAC3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA GTPase cycle (Bos taurus)
GDIs block activation of RHOA (Bos taurus)
RHOA GDIs:RHOA:GDP [cytosol] (Bos taurus)
RHOA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA GAPs stimulate RHOA GTPase activity (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA GEFs activate RHOA (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOC GTPase cycle (Bos taurus)
GDIs block activation of RHOC (Bos taurus)
RHOC:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOC:GDP:ARHGDIA [cytosol] (Bos taurus)
RHOC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHOC GAPs stimulate RHOC GTPase activity (Bos taurus)
RHOC:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOC GEFs activate RHOC (Bos taurus)
GDP [cytosol]
RHOC:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOD GTPase cycle (Bos taurus)
RHOD GAPs stimulate RHOD GTPase activity (Bos taurus)
RHOD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHOD auto-activates (Bos taurus)
GDP [cytosol]
RHOD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHOF GTPase cycle (Bos taurus)
RHOF GAPs stimulate RHOF GTPase activity (Bos taurus)
RHOF:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOF auto-activates (Bos taurus)
GDP [cytosol]
RHOF:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOG GTPase cycle (Bos taurus)
GDIs block activation of RHOG (Bos taurus)
RHOG GDIs:RHOG:GDP [cytosol] (Bos taurus)
RHOG:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOG GAPs stimulate RHOG GTPase activity (Bos taurus)
RHOG:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOG GEFs activate RHOG (Bos taurus)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOJ GTPase cycle (Bos taurus)
RHOJ GAPs stimulate RHOJ GTPase activity (Bos taurus)
RHOJ:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOJ GEFs activate RHOJ (Bos taurus)
GDP [cytosol]
RHOJ:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOQ GTPase cycle (Bos taurus)
RHOQ GAPs stimulate RHOQ GTPase activity (Bos taurus)
RHOQ:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOQ GEFs activate RHOQ (Bos taurus)
GDP [cytosol]
RHOQ:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOU GTPase cycle (Bos taurus)
Phosphorylated RHOU translocates to the endosome membrane (Bos taurus)
p-Y254-RHOU:GDP [endosome membrane] (Bos taurus)
GDP [cytosol]
p-Y254-RHOU:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOU auto-activates (Bos taurus)
GDP [cytosol]
RHOU:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOV GTPase cycle (Bos taurus)
RHOV binds GTP (Bos taurus)
GDP [cytosol]
RHOV:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by WNT (Bos taurus)
Beta-catenin independent WNT signaling (Bos taurus)
Ca2+ pathway (Bos taurus)
WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)
GDP [cytosol]
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Bos taurus)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (o/t2):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Transport of small molecules (Bos taurus)
Aquaporin-mediated transport (Bos taurus)
Vasopressin regulates renal water homeostasis via Aquaporins (Bos taurus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Clathrin-mediated endocytosis (Bos taurus)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Clathrin recruits auxilins to the clathrin-coated vesicle (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB5 and GAPVD1 bind AP-2 (Bos taurus)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
DNM:GDP [cytosol] (Bos taurus)
GDP [cytosol]
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ARFGAPs stimulate ARF GTPase activity (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
COPII coat binds TRAPPCII and RAB1:GDP (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GDP [cytosol]
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Gap junction trafficking and regulation (Bos taurus)
Gap junction trafficking (Bos taurus)
Gap junction assembly (Bos taurus)
Transport of connexons to the plasma membrane (Bos taurus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Bos taurus)
Association of Golgi transport vesicles with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-dependent Golgi-to-ER retrograde traffic (Bos taurus)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
COPI vesicle uncoating at the ER (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 recruits ARF:GDP to the Golgi (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF (Bos taurus)
GDP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Retrograde COPI vesicles bind kinesin and microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Bos taurus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Bos taurus)
RAB18:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Bos taurus)
RAB18:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Bos taurus)
RAB18:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Bos taurus)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Intra-Golgi traffic (Bos taurus)
CYTH proteins stimulate ARF1 GTPase activity (Bos taurus)
ARF1:GDP:CYTH1,2,3,4 [Golgi membrane] (Bos taurus)
Arf1-GDP [Golgi membrane] (Bos taurus)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Bos taurus)
Fusion of early-endosome derived vesicles at the TGN (Bos taurus)
RAB6:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Fusion of late-endosome derived vesicles at the TGN (Bos taurus)
RAB9:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RIC1:RGP1 recruits RAB6:GDP to the TGN (Bos taurus)
RAB6:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Bos taurus)
RAB6:GDP [trans-Golgi network membrane] (Bos taurus)
GDP [cytosol]
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Bos taurus)
GDP [cytosol]
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Bos taurus)
RAB6:GDP [trans-Golgi network membrane] (Bos taurus)
GDP [cytosol]
Rab regulation of trafficking (Bos taurus)
RAB GEFs exchange GTP for GDP on RABs (Bos taurus)
DENND1s exchange GTP for GDP on RAB35 (Bos taurus)
GDP [cytosol]
GGC-RAB35:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB35:GDP [cytosol] (Bos taurus)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Bos taurus)
GDP [cytosol]
GCC-RAB12:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB12:GDP [cytosol] (Bos taurus)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Bos taurus)
GDP [cytosol]
GGC-RAB10:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB10:GDP [cytosol] (Bos taurus)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Bos taurus)
GDP [cytosol]
GGC-RAB39:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB39:GDP [cytosol] (Bos taurus)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Bos taurus)
GDP [cytosol]
GGC-RAB14:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB14:GDP [cytosol] (Bos taurus)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Bos taurus)
GDP [cytosol]
RAB32,RAB38:GDP:GDIs,CHMs [cytosol] (Bos taurus)
RAB32,RAB38:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Bos taurus)
GDP [cytosol]
GGC-RAB27:GDP:GDIs,CHMs [cytosol] (Bos taurus)
RAB27:GDP [cytosol] (Bos taurus)
GGC-RAB27A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GGC-RAB27B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Bos taurus)
GDP [cytosol]
GGC-RAB7:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB7:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Bos taurus)
GDP [cytosol]
GGC-RAB13:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB13:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Bos taurus)
GDP [cytosol]
GGC-RAB21:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB21:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Bos taurus)
GDP [cytosol]
GGC-RAB3A:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB3A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Bos taurus)
GDP [cytosol]
GGC-RAB31:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB31:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Bos taurus)
GDP [cytosol]
GGC-RAB18:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB18:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Bos taurus)
GDP [cytosol]
GGC-RAB5:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB5:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Bos taurus)
GDP [cytosol]
GGC-RAB8:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB8:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)
GDP [cytosol]
GGC-RAB9:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB9:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Bos taurus)
GDP [cytosol]
GGC-RAB6:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB6:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Bos taurus)
GDP [cytosol]
GGC-RAB1:GDP:GDIs,CHMs [cytosol] (Bos taurus)
GGC-RAB1:GDP [cytosol] (Bos taurus)
GGC-RAB1A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GGC-RAB1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TBC/RABGAPs (Bos taurus)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Bos taurus)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GDP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Bos taurus)
RAB33:GDP [Golgi membrane] (Bos taurus)
GDP [cytosol]
TBC1D2A accelerates GTP hydrolysis by RAB7 (Bos taurus)
RAB7A:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Bos taurus)
Golgi Associated Vesicle Biogenesis (Bos taurus)
trans-Golgi Network Coat Assembly (Bos taurus)
Arf1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
trans-Golgi Network Vesicle Scission (Bos taurus)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Bos taurus)
trans-Golgi Network Lysosomal Vesicle Scission (Bos taurus)
GDP [cytosol]
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Bos taurus)
Arf1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
trans-Golgi Network Coat Activation (Bos taurus)
GDP [cytosol]
Arf1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
Active MTORC1 binds the ULK1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MTORC1 dissociates from ULK complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Metaphase and Anaphase (Caenorhabditis elegans)
Mitotic Anaphase (Caenorhabditis elegans)
Nuclear Envelope (NE) Reassembly (Caenorhabditis elegans)
Postmitotic nuclear pore complex (NPC) reformation (Caenorhabditis elegans)
RAN stimulates fusion of nuclear envelope (NE) membranes (Caenorhabditis elegans)
RAN:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Caenorhabditis elegans)
GDP [cytosol]
RAN:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to starvation (Caenorhabditis elegans)
Amino acids regulate mTORC1 (Caenorhabditis elegans)
RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GDP:RagC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GDP:RagC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA,B:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
EPH-Ephrin signaling (Caenorhabditis elegans)
EPH-ephrin mediated repulsion of cells (Caenorhabditis elegans)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
EPHA-mediated growth cone collapse (Caenorhabditis elegans)
NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
EPHB-mediated forward signaling (Caenorhabditis elegans)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Caenorhabditis elegans)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Caenorhabditis elegans)
HRAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Caenorhabditis elegans)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
L1CAM interactions (Caenorhabditis elegans)
Recycling pathway of L1 (Caenorhabditis elegans)
Formation of clathrin coated vesicle (Caenorhabditis elegans)
GDP [cytosol]
Signal transduction by L1 (Caenorhabditis elegans)
Activation of Rac1 by VAV2 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
NCAM signaling for neurite out-growth (Caenorhabditis elegans)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Netrin-1 signaling (Caenorhabditis elegans)
DCC mediated attractive signaling (Caenorhabditis elegans)
Activation of Cdc42 (Caenorhabditis elegans)
GDP [cytosol]
CDC42:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rac1 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Semaphorin interactions (Caenorhabditis elegans)
Sema4D in semaphorin signaling (Caenorhabditis elegans)
Sema4D induced cell migration and growth-cone collapse (Caenorhabditis elegans)
Activation of Rho by LARG and PDZ-RhoGEF (Caenorhabditis elegans)
GDP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Caenorhabditis elegans)
Inactivation of Rho-GTP by p190RhoGAP (Caenorhabditis elegans)
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by ROBO receptors (Caenorhabditis elegans)
SLIT2:ROBO1 increases RHOA activity (Caenorhabditis elegans)
MYO9B inactivates RHOA (Caenorhabditis elegans)
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Drug ADME (Caenorhabditis elegans)
Azathioprine ADME (Caenorhabditis elegans)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Hemostasis (Caenorhabditis elegans)
Factors involved in megakaryocyte development and platelet production (Caenorhabditis elegans)
Kinesins (Caenorhabditis elegans)
Kinesins move along microtubules consuming ATP (Caenorhabditis elegans)
Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
GPVI-mediated activation cascade (Caenorhabditis elegans)
VAV1 is a GEF for Rho/Rac family GTPases (Caenorhabditis elegans)
GDP [cytosol]
VAV1 Rho/Rac effectors:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
GDP [cytosol]
VAV2 Rho/Rac effectors:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
GDP [cytosol]
VAV3 Rho/Rac effectors:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signal amplification (Caenorhabditis elegans)
ADP signalling through P2Y purinoceptor 12 (Caenorhabditis elegans)
Gi activation by P2Y purinoceptor 12 (Caenorhabditis elegans)
GDP [cytosol]
Thromboxane signalling through TP receptor (Caenorhabditis elegans)
G13 activation by TP receptor (Caenorhabditis elegans)
GDP [cytosol]
Gq activation by TP receptor (Caenorhabditis elegans)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Caenorhabditis elegans)
Thrombin-activated PARs activate G12/13 (Caenorhabditis elegans)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Caenorhabditis elegans)
GDP [cytosol]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Rap1 signalling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Rap1 signal termination by Rap1GAPs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Caenorhabditis elegans)
Downstream signaling events of B Cell Receptor (BCR) (Caenorhabditis elegans)
Activation of RAS in B cells (Caenorhabditis elegans)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Cytokine Signaling in Immune system (Caenorhabditis elegans)
FLT3 Signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Metabolism (Caenorhabditis elegans)
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Adrenaline,noradrenaline inhibits insulin secretion (Caenorhabditis elegans)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Caenorhabditis elegans)
GDP [cytosol]
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Caenorhabditis elegans)
G-alpha(i,o):GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Caenorhabditis elegans)
RAP1A exchanges GDP for GTP (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PCK1 phosphorylates OA to yield PEP (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Caenorhabditis elegans)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Caenorhabditis elegans)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Caenorhabditis elegans)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Caenorhabditis elegans)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of RNA (Caenorhabditis elegans)
Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
Addition of a second mannose to the N-glycan precursor by ALG2 (Caenorhabditis elegans)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Caenorhabditis elegans)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPI-mediated anterograde transport (Caenorhabditis elegans)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
COPII-mediated vesicle transport (Caenorhabditis elegans)
COPII coat binds TRAPPCII and RAB1:GDP (Caenorhabditis elegans)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Loss of SAR1B GTPase (Caenorhabditis elegans)
SAR1B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
GDP [cytosol]
SAR1B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB geranylgeranylation (Caenorhabditis elegans)
RGGT geranylgeranylates RAB proteins (Caenorhabditis elegans)
CHMs:GGC-RABs:GDP [cytosol] (Caenorhabditis elegans)
GGC-RABs:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Caenorhabditis elegans)
RABs:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RGGT:CHM binds RABs (Caenorhabditis elegans)
RABs:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Caenorhabditis elegans)
RABs:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Translation (Caenorhabditis elegans)
Eukaryotic Translation Initiation (Caenorhabditis elegans)
Cap-dependent Translation Initiation (Caenorhabditis elegans)
GTP hydrolysis and joining of the 60S ribosomal subunit (Caenorhabditis elegans)
eIF5B:GTP is hydrolyzed and released (Caenorhabditis elegans)
eIF5B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Recycling of eIF2:GDP (Caenorhabditis elegans)
Formation of eIF2:GDP:eIF2B intermediate (Caenorhabditis elegans)
eIF2:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
eIF2 activation (Caenorhabditis elegans)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
GABA receptor activation (Caenorhabditis elegans)
GABA B receptor activation (Caenorhabditis elegans)
Activation of GABAB receptors (Caenorhabditis elegans)
Adenylate cyclase inhibitory pathway (Caenorhabditis elegans)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Caenorhabditis elegans)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Caenorhabditis elegans)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Organelle biogenesis and maintenance (Caenorhabditis elegans)
Cilium Assembly (Caenorhabditis elegans)
Cargo trafficking to the periciliary membrane (Caenorhabditis elegans)
VxPx cargo-targeting to cilium (Caenorhabditis elegans)
RAB3IP and RAB8A bind to the ciliary targeting complex (Caenorhabditis elegans)
RAB3IP:RAB8A:GDP [cytosol] (Caenorhabditis elegans)
RAB8A:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB8A:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Caenorhabditis elegans)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB8A:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Intraflagellar transport (Caenorhabditis elegans)
Anterograde IFT (Caenorhabditis elegans)
anterograde IFT trains [ciliary tip] (Caenorhabditis elegans)
active kinesin-2 motors [ciliary tip] (Caenorhabditis elegans)
acetylated microtubule [axonemal microtubule] (Caenorhabditis elegans)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Caenorhabditis elegans)
beta tubulin:GDP [axonemal microtubule] (Caenorhabditis elegans)
GDP [cytosol]
anterograde IFT trains [cilium] (Caenorhabditis elegans)
active kinesin-2 motors [cilium] (Caenorhabditis elegans)
acetylated microtubule [axonemal microtubule] (Caenorhabditis elegans)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Caenorhabditis elegans)
beta tubulin:GDP [axonemal microtubule] (Caenorhabditis elegans)
GDP [cytosol]
Retrograde IFT (Caenorhabditis elegans)
retrograde IFT trains [ciliary tip] (Caenorhabditis elegans)
active dynein-2 motors [ciliary tip] (Caenorhabditis elegans)
acetylated microtubule [axonemal microtubule] (Caenorhabditis elegans)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Caenorhabditis elegans)
beta tubulin:GDP [axonemal microtubule] (Caenorhabditis elegans)
GDP [cytosol]
retrograde IFT trains [cilium] (Caenorhabditis elegans)
active dynein-2 motors [cilium] (Caenorhabditis elegans)
acetylated microtubule [axonemal microtubule] (Caenorhabditis elegans)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Caenorhabditis elegans)
beta tubulin:GDP [axonemal microtubule] (Caenorhabditis elegans)
GDP [cytosol]
Signal Transduction (Caenorhabditis elegans)
Death Receptor Signaling (Caenorhabditis elegans)
p75 NTR receptor-mediated signalling (Caenorhabditis elegans)
Cell death signalling via NRAGE, NRIF and NADE (Caenorhabditis elegans)
NRAGE signals death through JNK (Caenorhabditis elegans)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)
GDP [cytosol]
p75NTR regulates axonogenesis (Caenorhabditis elegans)
Axonal growth inhibition (RHOA activation) (Caenorhabditis elegans)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Caenorhabditis elegans)
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
MAF1 translocates to the nucleus (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
Intrinsic nucleotide exchange on RAS (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAS processing (Caenorhabditis elegans)
mature p21 RAS binds GDP (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
MTOR signalling (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Formation of active mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
GTP loading by Rheb (Caenorhabditis elegans)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
GDP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Rag dimer formation (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1-mediated signalling (Caenorhabditis elegans)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGC,RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (12/13) signalling events (Caenorhabditis elegans)
GEFs activate RhoA,B,C (Caenorhabditis elegans)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Caenorhabditis elegans)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Caenorhabditis elegans)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha (i) signalling events (Caenorhabditis elegans)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Caenorhabditis elegans)
G alpha (i):GDP:RGS [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Caenorhabditis elegans)
G alpha (i):GDP:RGS [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
GDP [cytosol]
Opioid Signalling (Caenorhabditis elegans)
G-protein activation (Caenorhabditis elegans)
G-protein alpha subunit is inactivated (Caenorhabditis elegans)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G-protein beta-gamma subunits rebind the alpha-GDP subunit (Caenorhabditis elegans)
G protein-GDP complex [plasma membrane] (Caenorhabditis elegans)
G-protein alpha:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Caenorhabditis elegans)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Caenorhabditis elegans)
G protein-GDP complex [plasma membrane] (Caenorhabditis elegans)
G-protein alpha:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G-protein mediated events (Caenorhabditis elegans)
Adenylate cyclase activating pathway (Caenorhabditis elegans)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Caenorhabditis elegans)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Caenorhabditis elegans)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Caenorhabditis elegans)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
PLC beta mediated events (Caenorhabditis elegans)
Inactivation of PLC beta (Caenorhabditis elegans)
G-protein alpha:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Caenorhabditis elegans)
GDP [cytosol]
G alpha (q) signalling events (Caenorhabditis elegans)
G alpha (q) in G (q):RGS complex is inactivated (Caenorhabditis elegans)
G alpha (q):GDP:RGS [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Caenorhabditis elegans)
G alpha (q):GDP:RGS [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Caenorhabditis elegans)
EGFR Transactivation by Gastrin (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)
GDP [cytosol]
G alpha (s) signalling events (Caenorhabditis elegans)
Liganded Gs-activating GPCR acts as a GEF for Gs (Caenorhabditis elegans)
GDP [cytosol]
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Caenorhabditis elegans)
G alpha (s):GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Caenorhabditis elegans)
G alpha (s):GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha (z) signalling events (Caenorhabditis elegans)
G alpha (z) in G alpha (z):RGS complex is inactivated (Caenorhabditis elegans)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Caenorhabditis elegans)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by PTK6 (Caenorhabditis elegans)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Caenorhabditis elegans)
ARHGAP35 stimulates RHOA GTPase activity (Caenorhabditis elegans)
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
Estrogen-stimulated signaling through PRKCZ (Caenorhabditis elegans)
PRKCZ recruits RAS in response to estrogen stimulation (Caenorhabditis elegans)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Caenorhabditis elegans)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by EGFR (Caenorhabditis elegans)
GRB2 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
SHC1 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by ERBB2 (Caenorhabditis elegans)
GRB2 events in ERBB2 signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR (Caenorhabditis elegans)
Signaling by FGFR1 (Caenorhabditis elegans)
Downstream signaling of activated FGFR1 (Caenorhabditis elegans)
FRS-mediated FGFR1 signaling (Caenorhabditis elegans)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Caenorhabditis elegans)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR2 (Caenorhabditis elegans)
Downstream signaling of activated FGFR2 (Caenorhabditis elegans)
FRS-mediated FGFR2 signaling (Caenorhabditis elegans)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Caenorhabditis elegans)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR3 (Caenorhabditis elegans)
Downstream signaling of activated FGFR3 (Caenorhabditis elegans)
FRS-mediated FGFR3 signaling (Caenorhabditis elegans)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Caenorhabditis elegans)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR4 (Caenorhabditis elegans)
Downstream signaling of activated FGFR4 (Caenorhabditis elegans)
FRS-mediated FGFR4 signaling (Caenorhabditis elegans)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Caenorhabditis elegans)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by MET (Caenorhabditis elegans)
MET activates RAS signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
MET promotes cell motility (Caenorhabditis elegans)
MET activates RAP1 and RAC1 (Caenorhabditis elegans)
DOCK7 activates RAC1 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAPGEF1 activates RAP1 (Caenorhabditis elegans)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by PDGF (Caenorhabditis elegans)
Downstream signal transduction (Caenorhabditis elegans)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by SCF-KIT (Caenorhabditis elegans)
Activation of RAC1 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Caenorhabditis elegans)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
p-VAV family:PIP3 binds RAC1:GDP (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
Miro GTPase Cycle (Caenorhabditis elegans)
RHOT1 GTPase cycle (Caenorhabditis elegans)
RHOT1 hydrolyzes GTP (Caenorhabditis elegans)
RHOT1:GDP [mitochondrial outer membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOT2 GTPase cycle (Caenorhabditis elegans)
RHOT2 hydrolyzes GTP (Caenorhabditis elegans)
RHOT1:GDP [mitochondrial outer membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Rho GTPases (Caenorhabditis elegans)
RHO GTPase cycle (Caenorhabditis elegans)
CDC42 GTPase cycle (Caenorhabditis elegans)
CDC42 GAPs stimulate CDC42 GTPase activity (Caenorhabditis elegans)
CDC42:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
CDC42 GDIs block activation of CDC42 (Caenorhabditis elegans)
CDC42:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
CDC42:GDP:CDC42 GDIs [cytosol] (Caenorhabditis elegans)
CDC42:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
CDC42 GEFs activate CDC42 (Caenorhabditis elegans)
GDP [cytosol]
CDC42:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC1 GTPase cycle (Caenorhabditis elegans)
RAC1 GAPs stimulate RAC1 GTPase activity (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC1 GDIs block activation of RAC1 (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP:RAC1 GDIs [cytosol] (Caenorhabditis elegans)
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAC1 GEFs activate RAC1 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC2 GTPase cycle (Caenorhabditis elegans)
RAC2 GAPs stimulate RAC2 GTPase activity (Caenorhabditis elegans)
RAC2:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC2 GDIs block activation of RAC2 (Caenorhabditis elegans)
ARHGDIA:RAC2:GDP [cytosol] (Caenorhabditis elegans)
RAC2:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC2 GEFs activate RAC2 (Caenorhabditis elegans)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC3 GTPase cycle (Caenorhabditis elegans)
RAC3 GAPs stimulate RAC3 GTPase activity (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC3 GDIs block activation of RAC3 (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RAC3:GDP:RAC3 GDIs [cytosol] (Caenorhabditis elegans)
RAC1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAC3 GEFs activate RAC3 (Caenorhabditis elegans)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOA GTPase cycle (Caenorhabditis elegans)
GDIs block activation of RHOA (Caenorhabditis elegans)
RHOA GDIs:RHOA:GDP [cytosol] (Caenorhabditis elegans)
RHOA:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOA GAPs stimulate RHOA GTPase activity (Caenorhabditis elegans)
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOA GEFs activate RHOA (Caenorhabditis elegans)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOB GTPase cycle (Caenorhabditis elegans)
GDIs block activation of RHOB (Caenorhabditis elegans)
RHOB:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOB:GDP:RHOB GDIs [cytosol] (Caenorhabditis elegans)
RHOB:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RHOB GAPs stimulate RHOB GTPase activity (Caenorhabditis elegans)
RHOB:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOB GEFs activate RHOB (Caenorhabditis elegans)
GDP [cytosol]
RHOB:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOD GTPase cycle (Caenorhabditis elegans)
RHOD GAPs stimulate RHOD GTPase activity (Caenorhabditis elegans)
RHOD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RHOD auto-activates (Caenorhabditis elegans)
GDP [cytosol]
RHOD:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RHOF GTPase cycle (Caenorhabditis elegans)
RHOF GAPs stimulate RHOF GTPase activity (Caenorhabditis elegans)
RHOF:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOF auto-activates (Caenorhabditis elegans)
GDP [cytosol]
RHOF:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOG GTPase cycle (Caenorhabditis elegans)
GDIs block activation of RHOG (Caenorhabditis elegans)
RHOG GDIs:RHOG:GDP [cytosol] (Caenorhabditis elegans)
RHOG:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOG GAPs stimulate RHOG GTPase activity (Caenorhabditis elegans)
RHOG:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOG GEFs activate RHOG (Caenorhabditis elegans)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOJ GTPase cycle (Caenorhabditis elegans)
RHOJ GAPs stimulate RHOJ GTPase activity (Caenorhabditis elegans)
RHOJ:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOJ GEFs activate RHOJ (Caenorhabditis elegans)
GDP [cytosol]
RHOJ:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOQ GTPase cycle (Caenorhabditis elegans)
RHOQ GAPs stimulate RHOQ GTPase activity (Caenorhabditis elegans)
RHOQ:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOQ GEFs activate RHOQ (Caenorhabditis elegans)
GDP [cytosol]
RHOQ:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOU GTPase cycle (Caenorhabditis elegans)
Phosphorylated RHOU translocates to the endosome membrane (Caenorhabditis elegans)
p-Y254-RHOU:GDP [endosome membrane] (Caenorhabditis elegans)
GDP [cytosol]
p-Y254-RHOU:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOU auto-activates (Caenorhabditis elegans)
GDP [cytosol]
RHOU:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
RHOV GTPase cycle (Caenorhabditis elegans)
RHOV binds GTP (Caenorhabditis elegans)
GDP [cytosol]
RHOV:GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
Ca2+ pathway (Caenorhabditis elegans)
WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (o/t2):GDP [plasma membrane] (Caenorhabditis elegans)
GDP [cytosol]
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPI-mediated anterograde transport (Caenorhabditis elegans)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
COPII-mediated vesicle transport (Caenorhabditis elegans)
COPII coat binds TRAPPCII and RAB1:GDP (Caenorhabditis elegans)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Loss of SAR1B GTPase (Caenorhabditis elegans)
SAR1B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
GDP [cytosol]
SAR1B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
Golgi-to-ER retrograde transport (Caenorhabditis elegans)
COPI-dependent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
COPI vesicle uncoating at the ER (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)
Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Caenorhabditis elegans)
Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Caenorhabditis elegans)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
RAB18:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Caenorhabditis elegans)
RAB18:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
RAB18:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Caenorhabditis elegans)
RAB43 hydrolyses GTP (Caenorhabditis elegans)
RAB43:GDP:USP6NL [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB43:GDP [trans-Golgi network membrane] (Caenorhabditis elegans)
GDP [cytosol]
RIC1:RGP1 recruits RAB6:GDP to the TGN (Caenorhabditis elegans)
RAB6:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB6:GDP [trans-Golgi network membrane] (Caenorhabditis elegans)
GDP [cytosol]
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB6:GDP [trans-Golgi network membrane] (Caenorhabditis elegans)
GDP [cytosol]
Rab regulation of trafficking (Caenorhabditis elegans)
RAB GEFs exchange GTP for GDP on RABs (Caenorhabditis elegans)
DENND1s exchange GTP for GDP on RAB35 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB35:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB35:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB10:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB10:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB39:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB39:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB14:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB14:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB27:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
RAB27:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB27A:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB27B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB7:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB7:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB13:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB13:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB21:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB21:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB3A:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB3A:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB18:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB18:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB5:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB5:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB8:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB8:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB6:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB6:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB1:GDP:GDIs,CHMs [cytosol] (Caenorhabditis elegans)
GGC-RAB1:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB1A:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
GGC-RAB1B:GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
TBC/RABGAPs (Caenorhabditis elegans)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Caenorhabditis elegans)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GDP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Caenorhabditis elegans)
RAB33:GDP [Golgi membrane] (Caenorhabditis elegans)
GDP [cytosol]
TBC1D2A accelerates GTP hydrolysis by RAB7 (Caenorhabditis elegans)
RAB7A:GDP [lysosomal membrane] (Caenorhabditis elegans)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Caenorhabditis elegans)
Golgi Associated Vesicle Biogenesis (Caenorhabditis elegans)
trans-Golgi Network Coat Assembly (Caenorhabditis elegans)
Arf1-GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
trans-Golgi Network Vesicle Scission (Caenorhabditis elegans)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Caenorhabditis elegans)
trans-Golgi Network Lysosomal Vesicle Scission (Caenorhabditis elegans)
GDP [cytosol]
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Caenorhabditis elegans)
Arf1-GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
trans-Golgi Network Coat Activation (Caenorhabditis elegans)
GDP [cytosol]
Arf1-GDP [cytosol] (Caenorhabditis elegans)
GDP [cytosol]
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
Active MTORC1 binds the ULK1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Active MTORC1 phosphorylates ULK1 (Canis familiaris)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MTORC1 dissociates from ULK complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
RHEB:GDP [lysosomal membrane] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Selective autophagy (Canis familiaris)
Aggrephagy (Canis familiaris)
Aggresome dissociates from dynein and microtubule (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PolyUb-Misfolded proteins bind vimentin to form aggresome (Canis familiaris)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Nuclear Envelope (NE) Reassembly (Canis familiaris)
Postmitotic nuclear pore complex (NPC) reformation (Canis familiaris)
RAN stimulates fusion of nuclear envelope (NE) membranes (Canis familiaris)
RAN:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Canis familiaris)
GDP [cytosol]
RAN:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Canis familiaris)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Separation of Sister Chromatids (Canis familiaris)
ESPL1 (Separase) cleaves centromeric cohesin (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Separation of sister chromatids (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Sister Centromere:Kinetochore:Microtubules [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Mitotic Prometaphase (Canis familiaris)
EML4 and NUDC in mitotic spindle formation (Canis familiaris)
EML4 binds to microtubules (Canis familiaris)
EML4 homotrimer:Microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
EML4 recruits NUDC to mitotic spindle (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Kinetochore capture of astral microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Recruitment of NuMA to mitotic centrosomes (Canis familiaris)
Association of NuMA with microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Kinetochore assembly (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
The role of GTSE1 in G2/M progression after G2 checkpoint (Canis familiaris)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Canis familiaris)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GTSE1 binds microtubule lattice in interphase cells (Canis familiaris)
GTSE1:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to mechanical stimuli (Canis familiaris)
Response of endothelial cells to shear stress (Canis familiaris)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Canis familiaris)
ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
ADM:CALCLR:RAMP2:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Canis familiaris)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Cellular responses to stress (Canis familiaris)
Cellular response to starvation (Canis familiaris)
Amino acids regulate mTORC1 (Canis familiaris)
RRAGA,B exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Canis familiaris)
RagA,B:GDP:RagC,D:GTP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Canis familiaris)
RagA,B:GDP:RagC,D:GTP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Canis familiaris)
RRAGA,B:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPH-ephrin mediated repulsion of cells (Canis familiaris)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
EPHA-mediated growth cone collapse (Canis familiaris)
NGEF exchanges GTP for GDP on RHOA (Canis familiaris)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
EPHB-mediated forward signaling (Canis familiaris)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Canis familiaris)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Canis familiaris)
HRAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Canis familiaris)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
L1CAM interactions (Canis familiaris)
Recycling pathway of L1 (Canis familiaris)
Formation of clathrin coated vesicle (Canis familiaris)
GDP [cytosol]
Signal transduction by L1 (Canis familiaris)
Activation of Rac1 by VAV2 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
NCAM signaling for neurite out-growth (Canis familiaris)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Netrin-1 signaling (Canis familiaris)
DCC mediated attractive signaling (Canis familiaris)
Activation of Cdc42 (Canis familiaris)
GDP [cytosol]
CDC42:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Activation of Rac1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Semaphorin interactions (Canis familiaris)
Sema4D in semaphorin signaling (Canis familiaris)
Sema4D induced cell migration and growth-cone collapse (Canis familiaris)
Activation of Rho by LARG and PDZ-RhoGEF (Canis familiaris)
GDP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Canis familiaris)
Inactivation of Rho-GTP by p190RhoGAP (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by ROBO receptors (Canis familiaris)
SLIT2:ROBO1 increases RHOA activity (Canis familiaris)
MYO9B inactivates RHOA (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Drug ADME (Canis familiaris)
Azathioprine ADME (Canis familiaris)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
RHEB:GDP [lysosomal membrane] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
Tie2 Signaling (Canis familiaris)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Factors involved in megakaryocyte development and platelet production (Canis familiaris)
Kinesins (Canis familiaris)
Kinesins bind microtubules (Canis familiaris)
Kinesins:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Kinesins move along microtubules consuming ATP (Canis familiaris)
Kinesins:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Platelet activation, signaling and aggregation (Canis familiaris)
GPVI-mediated activation cascade (Canis familiaris)
VAV1 is a GEF for Rho/Rac family GTPases (Canis familiaris)
GDP [cytosol]
VAV1 Rho/Rac effectors:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Canis familiaris)
GDP [cytosol]
VAV2 Rho/Rac effectors:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Canis familiaris)
GDP [cytosol]
VAV3 Rho/Rac effectors:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Canis familiaris)
Integrin signaling (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signal amplification (Canis familiaris)
ADP signalling through P2Y purinoceptor 12 (Canis familiaris)
Gi activation by P2Y purinoceptor 12 (Canis familiaris)
GDP [cytosol]
Thromboxane signalling through TP receptor (Canis familiaris)
G13 activation by TP receptor (Canis familiaris)
GDP [cytosol]
Gq activation by TP receptor (Canis familiaris)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Canis familiaris)
Thrombin-activated PARs activate G12/13 (Canis familiaris)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Canis familiaris)
GDP [cytosol]
Platelet homeostasis (Canis familiaris)
Prostacyclin signalling through prostacyclin receptor (Canis familiaris)
Gs activation by prostacyclin receptor (Canis familiaris)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Canis familiaris)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Class I MHC mediated antigen processing & presentation (Canis familiaris)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Canis familiaris)
Disassembly of COPII coated vesicle (Canis familiaris)
GDP [cytosol]
SAR1B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MHC class II antigen presentation (Canis familiaris)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Canis familiaris)
Arf1-GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Internalization of MHC II:Ii clathrin coated vesicle (Canis familiaris)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Canis familiaris)
GDP [cytosol]
Transport of antigen loaded MHC II molecules to surface (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Kinesins:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Rap1 signalling (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Rap1 signal termination by Rap1GAPs (Canis familiaris)
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Regulation of T cell activation by CD28 family (Canis familiaris)
Co-stimulation by CD28 (Canis familiaris)
CD28 dependent Vav1 pathway (Canis familiaris)
Activation of Cdc42 by pVav1 (Canis familiaris)
GDP [cytosol]
CDC42:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Activation of Rac1 by pVav1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of RAS in B cells (Canis familiaris)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Interferon Signaling (Canis familiaris)
Antiviral mechanism by IFN-stimulated genes (Canis familiaris)
PKR-mediated signaling (Canis familiaris)
p-PKR dimer phosphorylates MAPT (Canis familiaris)
MAPT-8:Microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Innate Immune System (Canis familiaris)
DAP12 interactions (Canis familiaris)
DAP12 signaling (Canis familiaris)
Activation of RAC1 by VAV2/3 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated MAPK activation (Canis familiaris)
Activation of RAC1 by VAV (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
Activation of RAC1 by CRKII:DOCK180:ELMO (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activation of RAC1 by VAV (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Mitochondrial Uncoupling (Canis familiaris)
UCP1 imports a proton (Canis familiaris)
Purine nucleotide [cytosol]
GDP [cytosol]
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Adrenaline,noradrenaline inhibits insulin secretion (Canis familiaris)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Canis familiaris)
GDP [cytosol]
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Canis familiaris)
G-alpha(i,o):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Canis familiaris)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Canis familiaris)
FFAR1:FFAR1 ligands activate Gq (Canis familiaris)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Canis familiaris)
GLP1R binds GLP1 (Canis familiaris)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
GLP1R binds GLP1R agonists (Canis familiaris)
GLP1R:GLP1R agonists [plasma membrane] (Canis familiaris)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAP1A exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PCK1 phosphorylates OA to yield PEP (Canis familiaris)
GDP [cytosol]
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Canis familiaris)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Canis familiaris)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Canis familiaris)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Canis familiaris)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)
GDP [cytosol]
Metabolism of RNA (Canis familiaris)
Nonsense-Mediated Decay (NMD) (Canis familiaris)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Canis familiaris)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SMG6 hydrolyzes mRNA with premature termination codon (Canis familiaris)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Canis familiaris)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Canis familiaris)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
Addition of a second mannose to the N-glycan precursor by ALG2 (Canis familiaris)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Canis familiaris)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPI-mediated anterograde transport (Canis familiaris)
ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
COPI vesicle uncoating (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Canis familiaris)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
COPII-mediated vesicle transport (Canis familiaris)
COPII coat binds TRAPPCII and RAB1:GDP (Canis familiaris)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Loss of SAR1B GTPase (Canis familiaris)
SAR1B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Nucleotide exchange on RAB1 (Canis familiaris)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Canis familiaris)
GDP [cytosol]
SAR1B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Canis familiaris)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Polyglycylated microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Canis familiaris)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Canis familiaris)
Polyglycyl beta tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
TTLLs polyglutamylate tubulin (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Polyglutamylated microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Polyglutamyl microtubule protofilament [cytosol] (Canis familiaris)
Polyglutamyl alpha-beta tubulin dimer [cytosol] (Canis familiaris)
Polyglutamyl beta tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB geranylgeranylation (Canis familiaris)
RGGT geranylgeranylates RAB proteins (Canis familiaris)
CHMs:GGC-RABs:GDP [cytosol] (Canis familiaris)
GGC-RABs:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Canis familiaris)
RABs:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RGGT:CHM binds RABs (Canis familiaris)
RABs:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Canis familiaris)
RABs:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Translation (Canis familiaris)
Eukaryotic Translation Elongation (Canis familiaris)
Regeneration of eEF1A:GTP by eEF1B activity (Canis familiaris)
eEF1A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
eEF1B:GDP exchange complex [cytosol] (Canis familiaris)
GDP [cytosol]
Eukaryotic Translation Initiation (Canis familiaris)
Cap-dependent Translation Initiation (Canis familiaris)
GTP hydrolysis and joining of the 60S ribosomal subunit (Canis familiaris)
eIF2:GTP is hydrolyzed, eIFs are released (Canis familiaris)
eIF2:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
eIF5B:GTP is hydrolyzed and released (Canis familiaris)
eIF5B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Recycling of eIF2:GDP (Canis familiaris)
Formation of eIF2:GDP:eIF2B intermediate (Canis familiaris)
eIF2:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Canis familiaris)
GDP [cytosol]
eIF2 activation (Canis familiaris)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Canis familiaris)
GDP [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
GABA receptor activation (Canis familiaris)
GABA B receptor activation (Canis familiaris)
Activation of GABAB receptors (Canis familiaris)
Adenylate cyclase inhibitory pathway (Canis familiaris)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Canis familiaris)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Canis familiaris)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Canis familiaris)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Organelle biogenesis and maintenance (Canis familiaris)
Cilium Assembly (Canis familiaris)
ATAT acetylates microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
acetylated microtubule [cytosol] (Canis familiaris)
acetylated microtubule protofilament [cytosol] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Anchoring of the basal body to the plasma membrane (Canis familiaris)
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
GDP [cytosol]
RAB8A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Canis familiaris)
VxPx cargo-targeting to cilium (Canis familiaris)
ASAP1 stimulates GTPase activity of ARF4 (Canis familiaris)
ARF4:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Canis familiaris)
GDP [cytosol]
ARF4:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)
RAB3IP:RAB8A:GDP [cytosol] (Canis familiaris)
RAB8A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
RAB8A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
RAB8A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
HDAC6 deacetylates microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
acetylated microtubule [cytosol] (Canis familiaris)
acetylated microtubule protofilament [cytosol] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Intraflagellar transport (Canis familiaris)
Anterograde IFT (Canis familiaris)
anterograde IFT trains [ciliary tip] (Canis familiaris)
active kinesin-2 motors [ciliary tip] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
anterograde IFT trains [cilium] (Canis familiaris)
active kinesin-2 motors [cilium] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
Assembly of the anterograde IFT train (Canis familiaris)
active kinesin-2 motors [cilium] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
anterograde IFT trains [cilium] (Canis familiaris)
active kinesin-2 motors [cilium] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
Assembly of the retrograde IFT train (Canis familiaris)
active dynein-2 motors [ciliary tip] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
retrograde IFT trains [ciliary tip] (Canis familiaris)
active dynein-2 motors [ciliary tip] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
Retrograde IFT (Canis familiaris)
retrograde IFT trains [ciliary tip] (Canis familiaris)
active dynein-2 motors [ciliary tip] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
retrograde IFT trains [cilium] (Canis familiaris)
active dynein-2 motors [cilium] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
The anterograde IFT train dissociates (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
anterograde IFT trains [ciliary tip] (Canis familiaris)
active kinesin-2 motors [ciliary tip] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
The retrograde IFT train dissociates (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
retrograde IFT trains [cilium] (Canis familiaris)
active dynein-2 motors [cilium] (Canis familiaris)
acetylated microtubule [axonemal microtubule] (Canis familiaris)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
Sensory Perception (Canis familiaris)
Olfactory Signaling Pathway (Canis familiaris)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Canis familiaris)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Canis familiaris)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
Bitter compound binds bitter taste receptor (TAS2R) (Canis familiaris)
TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Canis familiaris)
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Canis familiaris)
TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Visual phototransduction (Canis familiaris)
The phototransduction cascade (Canis familiaris)
Inactivation, recovery and regulation of the phototransduction cascade (Canis familiaris)
GNAT1-GTP hydrolyses its bound GTP to GDP (Canis familiaris)
GNAT1-GDP [photoreceptor disc membrane] (Canis familiaris)
GDP [cytosol]
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
p75 NTR receptor-mediated signalling (Canis familiaris)
Cell death signalling via NRAGE, NRIF and NADE (Canis familiaris)
NRAGE signals death through JNK (Canis familiaris)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Canis familiaris)
GDP [cytosol]
p75NTR regulates axonogenesis (Canis familiaris)
Axonal growth inhibition (RHOA activation) (Canis familiaris)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
The p75NTR:NgR:MDGI binds RHOA-GDI (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Axonal growth stimulation (Canis familiaris)
NGF binding to p75NTR inactivates RHOA (Canis familiaris)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:NGF [plasma membrane] (Canis familiaris)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
p75NTR and RHOA-GDI interact (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Canis familiaris)
RHOA:GDP:ARHGDIA [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Integrin signaling (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
PTEN Regulation (Canis familiaris)
Regulation of PTEN gene transcription (Canis familiaris)
MAF1 translocates to the nucleus (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
Intrinsic nucleotide exchange on RAS (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Canis familiaris)
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAS processing (Canis familiaris)
mature p21 RAS binds GDP (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Regulation of RAS by GAPs (Canis familiaris)
RAS GAPs stimulate RAS GTPase activity (Canis familiaris)
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
MTOR signalling (Canis familiaris)
AKT1S1 (PRAS40) binds mTORC1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Canis familiaris)
AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
RHEB:GDP [lysosomal membrane] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Formation of active mTORC1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GTP loading by Rheb (Canis familiaris)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Canis familiaris)
GDP [cytosol]
Rag dimer formation (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Ragulator binds Rag dimers (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SLC38A9 binds Ragulator:Rag dimers (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Canis familiaris)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1-mediated signalling (Canis familiaris)
Phosphorylation of 4E-BP1 by activated mTORC1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGC,RRAGD:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RRAGD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (12/13) signalling events (Canis familiaris)
GEFs activate RhoA,B,C (Canis familiaris)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Canis familiaris)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Canis familiaris)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha (i) signalling events (Canis familiaris)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Canis familiaris)
G alpha (i):GDP:RGS [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Canis familiaris)
G alpha (i):GDP:RGS [plasma membrane] (Canis familiaris)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
GDP [cytosol]
Opioid Signalling (Canis familiaris)
G-protein activation (Canis familiaris)
G-protein alpha subunit is inactivated (Canis familiaris)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
G-protein beta-gamma subunits rebind the alpha-GDP subunit (Canis familiaris)
G protein-GDP complex [plasma membrane] (Canis familiaris)
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
The high affinity receptor complex binds to G-protein (Canis familiaris)
G protein-GDP complex [plasma membrane] (Canis familiaris)
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Canis familiaris)
G protein-GDP complex [plasma membrane] (Canis familiaris)
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Canis familiaris)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Canis familiaris)
G protein-GDP complex [plasma membrane] (Canis familiaris)
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
G-protein mediated events (Canis familiaris)
Adenylate cyclase activating pathway (Canis familiaris)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Canis familiaris)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Canis familiaris)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Canis familiaris)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Canis familiaris)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Canis familiaris)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
GDP [cytosol]
PLC beta mediated events (Canis familiaris)
Inactivation of PLC beta (Canis familiaris)
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Canis familiaris)
GDP [cytosol]
G alpha (q) signalling events (Canis familiaris)
G alpha (q) in G (q):RGS complex is inactivated (Canis familiaris)
G alpha (q):GDP:RGS [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Canis familiaris)
G alpha (q):GDP:RGS [plasma membrane] (Canis familiaris)
GDP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Canis familiaris)
EGFR Transactivation by Gastrin (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
GDP [cytosol]
G alpha (s) signalling events (Canis familiaris)
GPER1 signaling (Canis familiaris)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Canis familiaris)
GDP [cytosol]
GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] (Canis familiaris)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
GPER:Heterotrimeric G-protein Gs binds ESTG (Canis familiaris)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] (Canis familiaris)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha (z) signalling events (Canis familiaris)
G alpha (z) in G alpha (z):RGS complex is inactivated (Canis familiaris)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Canis familiaris)
GDP [cytosol]
G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Canis familiaris)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Canis familiaris)
GDP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Canis familiaris)
GDP [cytosol]
GPCR ligand binding (Canis familiaris)
Class B/2 (Secretin family receptors) (Canis familiaris)
Glucagon-type ligand receptors (Canis familiaris)
GLP1R binds GLP1 (Canis familiaris)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by Hedgehog (Canis familiaris)
Hedgehog 'off' state (Canis familiaris)
KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Canis familiaris)
KIF7:microtubule [ciliary tip] (Canis familiaris)
microtubule [axonemal microtubule] (Canis familiaris)
alpha-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
microtubule [axonemal microtubule] (Canis familiaris)
alpha-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Canis familiaris)
KIF7:microtubule [ciliary tip] (Canis familiaris)
microtubule [axonemal microtubule] (Canis familiaris)
alpha-beta tubulin dimer [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Canis familiaris)
Signaling by PTK6 (Canis familiaris)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Canis familiaris)
ARHGAP35 stimulates RHOA GTPase activity (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RASA1 stimulates RAS GTPase activity (Canis familiaris)
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Extra-nuclear estrogen signaling (Canis familiaris)
Estrogen-stimulated signaling through PRKCZ (Canis familiaris)
PRKCZ recruits RAS in response to estrogen stimulation (Canis familiaris)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Canis familiaris)
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Canis familiaris)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Canis familiaris)
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by EGFR (Canis familiaris)
GRB2 events in EGFR signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
SHC1 events in EGFR signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by ERBB2 (Canis familiaris)
GRB2 events in ERBB2 signaling (Canis familiaris)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by ERBB4 (Canis familiaris)
SHC1 events in ERBB4 signaling (Canis familiaris)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by FGFR (Canis familiaris)
Signaling by FGFR1 (Canis familiaris)
Downstream signaling of activated FGFR1 (Canis familiaris)
FRS-mediated FGFR1 signaling (Canis familiaris)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Canis familiaris)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by FGFR2 (Canis familiaris)
Downstream signaling of activated FGFR2 (Canis familiaris)
FRS-mediated FGFR2 signaling (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Canis familiaris)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by FGFR3 (Canis familiaris)
Downstream signaling of activated FGFR3 (Canis familiaris)
FRS-mediated FGFR3 signaling (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Canis familiaris)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
FRS-mediated FGFR4 signaling (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Canis familiaris)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by MET (Canis familiaris)
MET activates RAS signaling (Canis familiaris)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
MET promotes cell motility (Canis familiaris)
MET activates RAP1 and RAC1 (Canis familiaris)
DOCK7 activates RAC1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAPGEF1 activates RAP1 (Canis familiaris)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
ARMS-mediated activation (Canis familiaris)
C3G stimulates nucleotide exchange on Rap1 (Canis familiaris)
GDP [cytosol]
Rap1-GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Canis familiaris)
Activated NTRK2 signals through FYN (Canis familiaris)
NTRK2 activates RAC1 (Canis familiaris)
DOCK3 activates RAC1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by PDGF (Canis familiaris)
Downstream signal transduction (Canis familiaris)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by SCF-KIT (Canis familiaris)
Activation of RAC1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Canis familiaris)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Canis familiaris)
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
p-VAV family:PIP3 binds RAC1:GDP (Canis familiaris)
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Canis familiaris)
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Miro GTPase Cycle (Canis familiaris)
RHOT1 GTPase cycle (Canis familiaris)
RHOT1 hydrolyzes GTP (Canis familiaris)
RHOT1:GDP [mitochondrial outer membrane] (Canis familiaris)
GDP [cytosol]
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate Formins (Canis familiaris)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Canis familiaris)
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHO GTPase cycle (Canis familiaris)
CDC42 GTPase cycle (Canis familiaris)
CDC42 GAPs stimulate CDC42 GTPase activity (Canis familiaris)
CDC42:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
CDC42 GDIs block activation of CDC42 (Canis familiaris)
CDC42:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
CDC42:GDP:CDC42 GDIs [cytosol] (Canis familiaris)
CDC42:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
CDC42 GEFs activate CDC42 (Canis familiaris)
GDP [cytosol]
CDC42:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC1 GTPase cycle (Canis familiaris)
RAC1 GAPs stimulate RAC1 GTPase activity (Canis familiaris)
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC1 GDIs block activation of RAC1 (Canis familiaris)
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC1:GDP:RAC1 GDIs [cytosol] (Canis familiaris)
RAC1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAC1 GEFs activate RAC1 (Canis familiaris)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC2 GTPase cycle (Canis familiaris)
RAC2 GAPs stimulate RAC2 GTPase activity (Canis familiaris)
RAC2:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC2 GDIs block activation of RAC2 (Canis familiaris)
ARHGDIA:RAC2:GDP [cytosol] (Canis familiaris)
RAC2:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC2 GEFs activate RAC2 (Canis familiaris)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC3 GTPase cycle (Canis familiaris)
RAC3 GAPs stimulate RAC3 GTPase activity (Canis familiaris)
RAC3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC3 GDIs block activation of RAC3 (Canis familiaris)
RAC3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RAC3:GDP:RAC3 GDIs [cytosol] (Canis familiaris)
RAC3:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAC3 GEFs activate RAC3 (Canis familiaris)
GDP [cytosol]
RAC3:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA GTPase cycle (Canis familiaris)
GDIs block activation of RHOA (Canis familiaris)
RHOA GDIs:RHOA:GDP [cytosol] (Canis familiaris)
RHOA:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA GAPs stimulate RHOA GTPase activity (Canis familiaris)
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOA GEFs activate RHOA (Canis familiaris)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOB GTPase cycle (Canis familiaris)
GDIs block activation of RHOB (Canis familiaris)
RHOB:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOB:GDP:RHOB GDIs [cytosol] (Canis familiaris)
RHOB:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHOB GAPs stimulate RHOB GTPase activity (Canis familiaris)
RHOB:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOB GEFs activate RHOB (Canis familiaris)
GDP [cytosol]
RHOB:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOC GTPase cycle (Canis familiaris)
GDIs block activation of RHOC (Canis familiaris)
RHOC:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOC:GDP:ARHGDIA [cytosol] (Canis familiaris)
RHOC:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHOC GAPs stimulate RHOC GTPase activity (Canis familiaris)
RHOC:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOC GEFs activate RHOC (Canis familiaris)
GDP [cytosol]
RHOC:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOD GTPase cycle (Canis familiaris)
RHOD GAPs stimulate RHOD GTPase activity (Canis familiaris)
RHOD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHOD auto-activates (Canis familiaris)
GDP [cytosol]
RHOD:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHOF GTPase cycle (Canis familiaris)
RHOF GAPs stimulate RHOF GTPase activity (Canis familiaris)
RHOF:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOF auto-activates (Canis familiaris)
GDP [cytosol]
RHOF:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOG GTPase cycle (Canis familiaris)
GDIs block activation of RHOG (Canis familiaris)
RHOG GDIs:RHOG:GDP [cytosol] (Canis familiaris)
RHOG:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOG GAPs stimulate RHOG GTPase activity (Canis familiaris)
RHOG:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOG GEFs activate RHOG (Canis familiaris)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOJ GTPase cycle (Canis familiaris)
RHOJ GAPs stimulate RHOJ GTPase activity (Canis familiaris)
RHOJ:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOJ GEFs activate RHOJ (Canis familiaris)
GDP [cytosol]
RHOJ:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOQ GTPase cycle (Canis familiaris)
RHOQ GAPs stimulate RHOQ GTPase activity (Canis familiaris)
RHOQ:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOQ GEFs activate RHOQ (Canis familiaris)
GDP [cytosol]
RHOQ:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOU GTPase cycle (Canis familiaris)
Phosphorylated RHOU translocates to the endosome membrane (Canis familiaris)
p-Y254-RHOU:GDP [endosome membrane] (Canis familiaris)
GDP [cytosol]
p-Y254-RHOU:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOU auto-activates (Canis familiaris)
GDP [cytosol]
RHOU:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
RHOV GTPase cycle (Canis familiaris)
RHOV binds GTP (Canis familiaris)
GDP [cytosol]
RHOV:GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Signaling by WNT (Canis familiaris)
Beta-catenin independent WNT signaling (Canis familiaris)
Ca2+ pathway (Canis familiaris)
WNT:FZD complex promotes G-protein nucleotide exchange (Canis familiaris)
GDP [cytosol]
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Canis familiaris)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Canis familiaris)
G-protein alpha (o/t2):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Transport of small molecules (Canis familiaris)
Aquaporin-mediated transport (Canis familiaris)
Vasopressin regulates renal water homeostasis via Aquaporins (Canis familiaris)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Canis familiaris)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
GDP [cytosol]
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Clathrin recruits auxilins to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB5 and GAPVD1 bind AP-2 (Canis familiaris)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GDP [cytosol]
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
DNM:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
ER to Golgi Anterograde Transport (Canis familiaris)
COPI-mediated anterograde transport (Canis familiaris)
ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
COPI vesicle uncoating (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Canis familiaris)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
COPII-mediated vesicle transport (Canis familiaris)
COPII coat binds TRAPPCII and RAB1:GDP (Canis familiaris)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Loss of SAR1B GTPase (Canis familiaris)
SAR1B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Nucleotide exchange on RAB1 (Canis familiaris)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Canis familiaris)
GDP [cytosol]
SAR1B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Gap junction trafficking and regulation (Canis familiaris)
Gap junction trafficking (Canis familiaris)
Gap junction assembly (Canis familiaris)
Transport of connexons to the plasma membrane (Canis familiaris)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Canis familiaris)
Association of Golgi transport vesicles with microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
Golgi-to-ER retrograde transport (Canis familiaris)
COPI-dependent Golgi-to-ER retrograde traffic (Canis familiaris)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
COPI vesicle uncoating at the ER (Canis familiaris)
RAB1:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 recruits ARF:GDP to the Golgi (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF (Canis familiaris)
GDP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Canis familiaris)
ARF:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Retrograde COPI vesicles bind kinesin and microtubules (Canis familiaris)
Kinesins:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
Kinesins:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Canis familiaris)
Kinesins:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
Kinesins:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Canis familiaris)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Canis familiaris)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Canis familiaris)
RAB18:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Canis familiaris)
RAB18:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Canis familiaris)
RAB18:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Intra-Golgi traffic (Canis familiaris)
CYTH proteins stimulate ARF1 GTPase activity (Canis familiaris)
ARF1:GDP:CYTH1,2,3,4 [Golgi membrane] (Canis familiaris)
Arf1-GDP [Golgi membrane] (Canis familiaris)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Canis familiaris)
Fusion of late-endosome derived vesicles at the TGN (Canis familiaris)
RAB9:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Rab regulation of trafficking (Canis familiaris)
RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
DENND1s exchange GTP for GDP on RAB35 (Canis familiaris)
GDP [cytosol]
GGC-RAB35:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB35:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Canis familiaris)
GDP [cytosol]
GCC-RAB12:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB12:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Canis familiaris)
GDP [cytosol]
GGC-RAB10:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB10:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Canis familiaris)
GDP [cytosol]
GGC-RAB39:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB39:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Canis familiaris)
GDP [cytosol]
RAB32,RAB38:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
RAB32,RAB38:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Canis familiaris)
GDP [cytosol]
GGC-RAB27:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB27A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Canis familiaris)
GDP [cytosol]
GGC-RAB7:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB7:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Canis familiaris)
GDP [cytosol]
GGC-RAB13:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB13:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Canis familiaris)
GDP [cytosol]
GGC-RAB3A:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB3A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Canis familiaris)
GDP [cytosol]
GGC-RAB18:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB18:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Canis familiaris)
GDP [cytosol]
GGC-RAB5:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB5:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Canis familiaris)
GDP [cytosol]
GGC-RAB8:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB8:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Canis familiaris)
GDP [cytosol]
GGC-RAB9:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB9:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Canis familiaris)
GDP [cytosol]
GGC-RAB1:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
GGC-RAB1:GDP [cytosol] (Canis familiaris)
GGC-RAB1A:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
GGC-RAB1B:GDP [cytosol] (Canis familiaris)
GDP [cytosol]
TBC/RABGAPs (Canis familiaris)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Canis familiaris)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GDP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Canis familiaris)
RAB33:GDP [Golgi membrane] (Canis familiaris)
GDP [cytosol]
TBC1D2A accelerates GTP hydrolysis by RAB7 (Canis familiaris)
RAB7A:GDP [lysosomal membrane] (Canis familiaris)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Canis familiaris)
Golgi Associated Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Coat Assembly (Canis familiaris)
Arf1-GDP [cytosol] (Canis familiaris)
GDP [cytosol]
trans-Golgi Network Vesicle Scission (Canis familiaris)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Lysosomal Vesicle Scission (Canis familiaris)
GDP [cytosol]
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Canis familiaris)
Arf1-GDP [cytosol] (Canis familiaris)
GDP [cytosol]
trans-Golgi Network Coat Activation (Canis familiaris)
GDP [cytosol]
Arf1-GDP [cytosol] (Canis familiaris)
GDP [cytosol]
Autophagy (Danio rerio)
Macroautophagy (Danio rerio)
Active MTORC1 phosphorylates ULK1 (Danio rerio)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Danio rerio)
RHEB:GDP [lysosomal membrane] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Selective autophagy (Danio rerio)
Aggrephagy (Danio rerio)
PolyUb-Misfolded proteins bind vimentin to form aggresome (Danio rerio)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Danio rerio)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Danio rerio)
Microtubule [cytosol] (Danio rerio)
Microtubule protofilament [cytosol] (Danio rerio)
alpha-beta tubulin dimer [cytosol] (Danio rerio)
beta-tubulin:GDP [cytosol] (Danio rerio)
GDP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Danio rerio)
Microtubule [cytosol] (Danio rerio)
Microtubule protofilament [cytosol] (Danio rerio)
alpha-beta tubulin dimer [cytosol] (Danio rerio)
beta-tubulin:GDP [cytosol] (Danio rerio)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Danio rerio)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Danio rerio)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Danio rerio)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Metaphase and Anaphase (Danio rerio)
Mitotic Anaphase (Danio rerio)
Nuclear Envelope (NE) Reassembly (Danio rerio)
Postmitotic nuclear pore complex (NPC) reformation (Danio rerio)
RAN stimulates fusion of nuclear envelope (NE) membranes (Danio rerio)
RAN:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Danio rerio)
GDP [cytosol]
RAN:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to starvation (Danio rerio)
Amino acids regulate mTORC1 (Danio rerio)
RRAGA,B exchanges GDP for GTP (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Danio rerio)
RagA,B:GDP:RagC,D:GTP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Danio rerio)
RagA,B:GDP:RagC,D:GTP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Danio rerio)
RRAGA,B:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGB:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPH-ephrin mediated repulsion of cells (Danio rerio)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Danio rerio)
GDP [cytosol]
RAC1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
GDP [cytosol]
RAC1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
EPHA-mediated growth cone collapse (Danio rerio)
NGEF exchanges GTP for GDP on RHOA (Danio rerio)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
EPHB-mediated forward signaling (Danio rerio)
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Danio rerio)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Danio rerio)
HRAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Netrin-1 signaling (Danio rerio)
DCC mediated attractive signaling (Danio rerio)
Activation of Cdc42 (Danio rerio)
GDP [cytosol]
CDC42:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Activation of Rac1 (Danio rerio)
GDP [cytosol]
RAC1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Semaphorin interactions (Danio rerio)
Sema4D in semaphorin signaling (Danio rerio)
Sema4D induced cell migration and growth-cone collapse (Danio rerio)
Activation of Rho by LARG and PDZ-RhoGEF (Danio rerio)
GDP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Danio rerio)
Inactivation of Rho-GTP by p190RhoGAP (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Metabolic Genes (Danio rerio)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Danio rerio)
RHEB:GDP [lysosomal membrane] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Hemostasis (Danio rerio)
Cell surface interactions at the vascular wall (Danio rerio)
Tie2 Signaling (Danio rerio)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Platelet activation, signaling and aggregation (Danio rerio)
Signal amplification (Danio rerio)
ADP signalling through P2Y purinoceptor 12 (Danio rerio)
Gi activation by P2Y purinoceptor 12 (Danio rerio)
GDP [cytosol]
Thromboxane signalling through TP receptor (Danio rerio)
G13 activation by TP receptor (Danio rerio)
GDP [cytosol]
Gq activation by TP receptor (Danio rerio)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Danio rerio)
Thrombin-activated PARs activate G12/13 (Danio rerio)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Danio rerio)
GDP [cytosol]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
MHC class II antigen presentation (Danio rerio)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Danio rerio)
Arf1-GDP [cytosol] (Danio rerio)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Danio rerio)
GDP [cytosol]
Rap1 signalling (Danio rerio)
Rap1 signal termination by Rap1GAPs (Danio rerio)
RAP1:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of RAS in B cells (Danio rerio)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Mitochondrial Uncoupling (Danio rerio)
UCP1 imports a proton (Danio rerio)
Purine nucleotide [cytosol]
GDP [cytosol]
Integration of energy metabolism (Danio rerio)
Regulation of insulin secretion (Danio rerio)
Adrenaline,noradrenaline inhibits insulin secretion (Danio rerio)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Danio rerio)
GDP [cytosol]
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Danio rerio)
G-alpha(i,o):GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Danio rerio)
GLP1R binds GLP1R agonists (Danio rerio)
GLP1R:GLP1R agonists [plasma membrane] (Danio rerio)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Danio rerio)
G alpha (s):GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Danio rerio)
G alpha (s):GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAP1A exchanges GDP for GTP (Danio rerio)
GDP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PCK1 phosphorylates OA to yield PEP (Danio rerio)
GDP [cytosol]
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Danio rerio)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Danio rerio)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Danio rerio)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Danio rerio)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Danio rerio)
GDP [cytosol]
Metabolism of RNA (Danio rerio)
Nonsense-Mediated Decay (NMD) (Danio rerio)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Danio rerio)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Danio rerio)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Danio rerio)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
Addition of the first mannose to the N-glycan precursor by ALG1 (Danio rerio)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Danio rerio)
Synthesis of dolichyl-phosphate mannose (Danio rerio)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Danio rerio)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Danio rerio)
ER to Golgi Anterograde Transport (Danio rerio)
COPI-mediated anterograde transport (Danio rerio)
GBF1 stimulates ARF nucleotide exchange (Danio rerio)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
ARF:GDP [cytosol] (Danio rerio)
GDP [cytosol]
COPII-mediated vesicle transport (Danio rerio)
Nucleotide exchange on RAB1 (Danio rerio)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
RAB1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Danio rerio)
GDP [cytosol]
SAR1B:GDP [cytosol] (Danio rerio)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Danio rerio)
RAB1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Danio rerio)
Synthesis of dolichyl-phosphate mannose (Danio rerio)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Danio rerio)
GDP [cytosol]
Protein ubiquitination (Danio rerio)
E3 ubiquitin ligases ubiquitinate target proteins (Danio rerio)
RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Danio rerio)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RNF152 polyubiquitinates RRAGA (Danio rerio)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Danio rerio)
RRAGA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAB geranylgeranylation (Danio rerio)
RGGT geranylgeranylates RAB proteins (Danio rerio)
CHMs:GGC-RABs:GDP [cytosol] (Danio rerio)
GGC-RABs:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Danio rerio)
RABs:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RGGT:CHM binds RABs (Danio rerio)
RABs:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Danio rerio)
RABs:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Translation (Danio rerio)
Eukaryotic Translation Initiation (Danio rerio)
Cap-dependent Translation Initiation (Danio rerio)
Recycling of eIF2:GDP (Danio rerio)
Formation of eIF2:GDP:eIF2B intermediate (Danio rerio)
eIF2:GDP [cytosol] (Danio rerio)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Danio rerio)
GDP [cytosol]
eIF2 activation (Danio rerio)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Danio rerio)
GDP [cytosol]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter receptors and postsynaptic signal transmission (Danio rerio)
GABA receptor activation (Danio rerio)
GABA B receptor activation (Danio rerio)
Activation of GABAB receptors (Danio rerio)
Adenylate cyclase inhibitory pathway (Danio rerio)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Danio rerio)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Danio rerio)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Danio rerio)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Organelle biogenesis and maintenance (Danio rerio)
Cilium Assembly (Danio rerio)
Cargo trafficking to the periciliary membrane (Danio rerio)
VxPx cargo-targeting to cilium (Danio rerio)
ASAP1 stimulates GTPase activity of ARF4 (Danio rerio)
ARF4:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAB3IP and RAB8A bind to the ciliary targeting complex (Danio rerio)
RAB3IP:RAB8A:GDP [cytosol] (Danio rerio)
RAB8A:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Danio rerio)
RAB8A:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Danio rerio)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Danio rerio)
RAB8A:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Sensory Perception (Danio rerio)
Olfactory Signaling Pathway (Danio rerio)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Danio rerio)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Danio rerio)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Sensory perception of taste (Danio rerio)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Danio rerio)
Bitter compound binds bitter taste receptor (TAS2R) (Danio rerio)
TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Danio rerio)
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Danio rerio)
TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signal Transduction (Danio rerio)
Death Receptor Signaling (Danio rerio)
p75 NTR receptor-mediated signalling (Danio rerio)
Cell death signalling via NRAGE, NRIF and NADE (Danio rerio)
NRAGE signals death through JNK (Danio rerio)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Danio rerio)
GDP [cytosol]
p75NTR regulates axonogenesis (Danio rerio)
Axonal growth inhibition (RHOA activation) (Danio rerio)
The p75NTR:NgR:MDGI binds RHOA-GDI (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Axonal growth stimulation (Danio rerio)
NGF binding to p75NTR inactivates RHOA (Danio rerio)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:NGF [plasma membrane] (Danio rerio)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
p75NTR and RHOA-GDI interact (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Danio rerio)
RHOA:GDP:ARHGDIA [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
PTEN Regulation (Danio rerio)
Regulation of PTEN gene transcription (Danio rerio)
MAF1 translocates to the nucleus (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
Intrinsic nucleotide exchange on RAS (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Danio rerio)
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAS processing (Danio rerio)
mature p21 RAS binds GDP (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
MTOR signalling (Danio rerio)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Danio rerio)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Danio rerio)
AMPK phosphorylates Raptor in the mTORC1 complex (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Danio rerio)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Danio rerio)
RHEB:GDP [lysosomal membrane] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Formation of active mTORC1 complex (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
GTP loading by Rheb (Danio rerio)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Danio rerio)
GDP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Danio rerio)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Danio rerio)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Rag dimer formation (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Ragulator binds Rag dimers (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SLC38A9 binds Ragulator:Rag dimers (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Danio rerio)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Danio rerio)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Danio rerio)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1-mediated signalling (Danio rerio)
Phosphorylation of 4E-BP1 by activated mTORC1 (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Danio rerio)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Danio rerio)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Danio rerio)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Danio rerio)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Danio rerio)
RagA,B:GTP:RagC,D:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (12/13) signalling events (Danio rerio)
GEFs activate RhoA,B,C (Danio rerio)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Danio rerio)
GDP [cytosol]
G alpha (i) signalling events (Danio rerio)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Danio rerio)
G alpha (i):GDP:RGS [plasma membrane] (Danio rerio)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Danio rerio)
G alpha (i):GDP:RGS [plasma membrane] (Danio rerio)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
GDP [cytosol]
Opioid Signalling (Danio rerio)
G-protein activation (Danio rerio)
G-protein alpha subunit is inactivated (Danio rerio)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
G-protein mediated events (Danio rerio)
Adenylate cyclase activating pathway (Danio rerio)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Danio rerio)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Danio rerio)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Danio rerio)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Danio rerio)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Danio rerio)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Danio rerio)
GDP [cytosol]
G alpha (q) signalling events (Danio rerio)
G alpha (q) in G (q):RGS complex is inactivated (Danio rerio)
G alpha (q):GDP:RGS [plasma membrane] (Danio rerio)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Danio rerio)
G alpha (q):GDP:RGS [plasma membrane] (Danio rerio)
GDP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Danio rerio)
EGFR Transactivation by Gastrin (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
Signaling by PTK6 (Danio rerio)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Danio rerio)
ARHGAP35 stimulates RHOA GTPase activity (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Danio rerio)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RASA1 stimulates RAS GTPase activity (Danio rerio)
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by EGFR (Danio rerio)
GRB2 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
SHC1 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by ERBB2 (Danio rerio)
GRB2 events in ERBB2 signaling (Danio rerio)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by ERBB4 (Danio rerio)
SHC1 events in ERBB4 signaling (Danio rerio)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by FGFR (Danio rerio)
Signaling by FGFR1 (Danio rerio)
Downstream signaling of activated FGFR1 (Danio rerio)
FRS-mediated FGFR1 signaling (Danio rerio)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Danio rerio)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by FGFR2 (Danio rerio)
Downstream signaling of activated FGFR2 (Danio rerio)
FRS-mediated FGFR2 signaling (Danio rerio)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Danio rerio)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by FGFR3 (Danio rerio)
Downstream signaling of activated FGFR3 (Danio rerio)
FRS-mediated FGFR3 signaling (Danio rerio)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Danio rerio)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by FGFR4 (Danio rerio)
Downstream signaling of activated FGFR4 (Danio rerio)
FRS-mediated FGFR4 signaling (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by MET (Danio rerio)
MET activates RAS signaling (Danio rerio)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by NTRKs (Danio rerio)
Signaling by NTRK1 (TRKA) (Danio rerio)
Signalling to ERKs (Danio rerio)
Prolonged ERK activation events (Danio rerio)
ARMS-mediated activation (Danio rerio)
C3G stimulates nucleotide exchange on Rap1 (Danio rerio)
GDP [cytosol]
Rap1-GDP [cytosol] (Danio rerio)
GDP [cytosol]
Signaling by PDGF (Danio rerio)
Downstream signal transduction (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by SCF-KIT (Danio rerio)
Activation of RAS by p-KIT bound SOS1 (Danio rerio)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Miro GTPase Cycle (Danio rerio)
RHOT1 GTPase cycle (Danio rerio)
RHOT1 hydrolyzes GTP (Danio rerio)
RHOT1:GDP [mitochondrial outer membrane] (Danio rerio)
GDP [cytosol]
RHOT2 GTPase cycle (Danio rerio)
RHOT2 hydrolyzes GTP (Danio rerio)
RHOT2:GDP [mitochondrial outer membrane] (Danio rerio)
GDP [cytosol]
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate Formins (Danio rerio)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Danio rerio)
RAC1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RHO GTPase cycle (Danio rerio)
CDC42 GTPase cycle (Danio rerio)
CDC42 GAPs stimulate CDC42 GTPase activity (Danio rerio)
CDC42:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
CDC42 GDIs block activation of CDC42 (Danio rerio)
CDC42:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
CDC42:GDP:CDC42 GDIs [cytosol] (Danio rerio)
CDC42:GDP [cytosol] (Danio rerio)
GDP [cytosol]
CDC42 GEFs activate CDC42 (Danio rerio)
GDP [cytosol]
CDC42:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC1 GTPase cycle (Danio rerio)
RAC1 GAPs stimulate RAC1 GTPase activity (Danio rerio)
RAC1:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC1 GDIs block activation of RAC1 (Danio rerio)
RAC1:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC1:GDP:RAC1 GDIs [cytosol] (Danio rerio)
RAC1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAC1 GEFs activate RAC1 (Danio rerio)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC2 GTPase cycle (Danio rerio)
RAC2 GAPs stimulate RAC2 GTPase activity (Danio rerio)
RAC2:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC2 GDIs block activation of RAC2 (Danio rerio)
ARHGDIA:RAC2:GDP [cytosol] (Danio rerio)
RAC2:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC2 GEFs activate RAC2 (Danio rerio)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC3 GTPase cycle (Danio rerio)
RAC3 GAPs stimulate RAC3 GTPase activity (Danio rerio)
RAC3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC3 GDIs block activation of RAC3 (Danio rerio)
RAC3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RAC3:GDP:RAC3 GDIs [cytosol] (Danio rerio)
RAC3:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAC3 GEFs activate RAC3 (Danio rerio)
GDP [cytosol]
RAC3:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA GTPase cycle (Danio rerio)
GDIs block activation of RHOA (Danio rerio)
RHOA GDIs:RHOA:GDP [cytosol] (Danio rerio)
RHOA:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA GAPs stimulate RHOA GTPase activity (Danio rerio)
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOA GEFs activate RHOA (Danio rerio)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOD GTPase cycle (Danio rerio)
RHOD GAPs stimulate RHOD GTPase activity (Danio rerio)
RHOD:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RHOD auto-activates (Danio rerio)
GDP [cytosol]
RHOD:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RHOF GTPase cycle (Danio rerio)
RHOF GAPs stimulate RHOF GTPase activity (Danio rerio)
RHOF:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOF auto-activates (Danio rerio)
GDP [cytosol]
RHOF:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOG GTPase cycle (Danio rerio)
GDIs block activation of RHOG (Danio rerio)
RHOG GDIs:RHOG:GDP [cytosol] (Danio rerio)
RHOG:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOG GAPs stimulate RHOG GTPase activity (Danio rerio)
RHOG:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOG GEFs activate RHOG (Danio rerio)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOQ GTPase cycle (Danio rerio)
RHOQ GAPs stimulate RHOQ GTPase activity (Danio rerio)
RHOQ:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOU GTPase cycle (Danio rerio)
Phosphorylated RHOU translocates to the endosome membrane (Danio rerio)
p-Y254-RHOU:GDP [endosome membrane] (Danio rerio)
GDP [cytosol]
p-Y254-RHOU:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOU auto-activates (Danio rerio)
GDP [cytosol]
RHOU:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
RHOV GTPase cycle (Danio rerio)
RHOV binds GTP (Danio rerio)
GDP [cytosol]
RHOV:GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Transport of small molecules (Danio rerio)
Aquaporin-mediated transport (Danio rerio)
Vasopressin regulates renal water homeostasis via Aquaporins (Danio rerio)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Danio rerio)
GDP [cytosol]
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Danio rerio)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Danio rerio)
G alpha (s):GDP [plasma membrane] (Danio rerio)
GDP [cytosol]
Vesicle-mediated transport (Danio rerio)
Membrane Trafficking (Danio rerio)
ER to Golgi Anterograde Transport (Danio rerio)
COPI-mediated anterograde transport (Danio rerio)
GBF1 stimulates ARF nucleotide exchange (Danio rerio)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
ARF:GDP [cytosol] (Danio rerio)
GDP [cytosol]
COPII-mediated vesicle transport (Danio rerio)
Nucleotide exchange on RAB1 (Danio rerio)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
RAB1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Danio rerio)
GDP [cytosol]
SAR1B:GDP [cytosol] (Danio rerio)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Danio rerio)
RAB1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Danio rerio)
Golgi-to-ER retrograde transport (Danio rerio)
COPI-dependent Golgi-to-ER retrograde traffic (Danio rerio)
COPI vesicle uncoating at the ER (Danio rerio)
RAB1:GDP [cytosol] (Danio rerio)
GDP [cytosol]
Rab regulation of trafficking (Danio rerio)
RAB GEFs exchange GTP for GDP on RABs (Danio rerio)
DENND6A,B exchange GTP for GDP on RAB14 (Danio rerio)
GDP [cytosol]
GGC-RAB14:GDP:GDIs,CHMs [cytosol] (Danio rerio)
GGC-RAB14:GDP [cytosol] (Danio rerio)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Danio rerio)
GDP [cytosol]
RAB32,RAB38:GDP:GDIs,CHMs [cytosol] (Danio rerio)
RAB32,RAB38:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Danio rerio)
GDP [cytosol]
GGC-RAB5:GDP:GDIs,CHMs [cytosol] (Danio rerio)
GGC-RAB5:GDP [cytosol] (Danio rerio)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Danio rerio)
GDP [cytosol]
GGC-RAB8:GDP:GDIs,CHMs [cytosol] (Danio rerio)
GGC-RAB8:GDP [cytosol] (Danio rerio)
GDP [cytosol]
TBC/RABGAPs (Danio rerio)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Danio rerio)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Danio rerio)
GDP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Danio rerio)
RAB33:GDP [Golgi membrane] (Danio rerio)
GDP [cytosol]
TBC1D2A accelerates GTP hydrolysis by RAB7 (Danio rerio)
RAB7A:GDP [lysosomal membrane] (Danio rerio)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Danio rerio)
Lysosome Vesicle Biogenesis (Danio rerio)
trans-Golgi Network Lysosomal Vesicle Scission (Danio rerio)
GDP [cytosol]
Autophagy (Dictyostelium discoideum)
Macroautophagy (Dictyostelium discoideum)
Active MTORC1 binds the ULK1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
MTORC1 dissociates from ULK complex (Dictyostelium discoideum)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Selective autophagy (Dictyostelium discoideum)
Aggrephagy (Dictyostelium discoideum)
Aggresome dissociates from dynein and microtubule (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Dictyostelium discoideum)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
M Phase (Dictyostelium discoideum)
Mitotic Metaphase and Anaphase (Dictyostelium discoideum)
Mitotic Anaphase (Dictyostelium discoideum)
Nuclear Envelope (NE) Reassembly (Dictyostelium discoideum)
Postmitotic nuclear pore complex (NPC) reformation (Dictyostelium discoideum)
RCC1 stimulates GDP to GTP exchange on RAN (Dictyostelium discoideum)
GDP [cytosol]
RAN:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Dictyostelium discoideum)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to starvation (Dictyostelium discoideum)
Amino acids regulate mTORC1 (Dictyostelium discoideum)
RRAGA,B exchanges GDP for GTP (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGA,B:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGA,B:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGA,B:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GDP:RagC,D:GTP [cytosol] (Dictyostelium discoideum)
RRAGA,B:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGA,B:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GDP:RagC,D:GTP [cytosol] (Dictyostelium discoideum)
RRAGA,B:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Hemostasis (Dictyostelium discoideum)
Platelet activation, signaling and aggregation (Dictyostelium discoideum)
Platelet Aggregation (Plug Formation) (Dictyostelium discoideum)
Integrin signaling (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Rap1 signalling (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Rap1 signal termination by Rap1GAPs (Dictyostelium discoideum)
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Metabolism (Dictyostelium discoideum)
Integration of energy metabolism (Dictyostelium discoideum)
Regulation of insulin secretion (Dictyostelium discoideum)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Dictyostelium discoideum)
RAP1A exchanges GDP for GTP (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
PCK1 phosphorylates OA to yield PEP (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Interconversion of nucleotide di- and triphosphates (Dictyostelium discoideum)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Dictyostelium discoideum)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Dictyostelium discoideum)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Dictyostelium discoideum)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Dictyostelium discoideum)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of RNA (Dictyostelium discoideum)
Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Dictyostelium discoideum)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
Addition of a second mannose to the N-glycan precursor by ALG2 (Dictyostelium discoideum)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Dictyostelium discoideum)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Dictyostelium discoideum)
ER to Golgi Anterograde Transport (Dictyostelium discoideum)
COPI-mediated anterograde transport (Dictyostelium discoideum)
ARFGAPs stimulate ARF GTPase activity (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Dictyostelium discoideum)
Dynein:Dynactin:microtubule [cytosol] (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Dictyostelium discoideum)
Dynein:Dynactin:microtubule [cytosol] (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Dictyostelium discoideum)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
COPII-mediated vesicle transport (Dictyostelium discoideum)
COPII coat binds TRAPPCII and RAB1:GDP (Dictyostelium discoideum)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Loss of SAR1B GTPase (Dictyostelium discoideum)
SAR1B:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Nucleotide exchange on RAB1 (Dictyostelium discoideum)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Dictyostelium discoideum)
GDP [cytosol]
SAR1B:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Dictyostelium discoideum)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Polyglycylated microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Dictyostelium discoideum)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
Polyglycyl beta tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Protein ubiquitination (Dictyostelium discoideum)
E3 ubiquitin ligases ubiquitinate target proteins (Dictyostelium discoideum)
RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Dictyostelium discoideum)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RNF152 polyubiquitinates RRAGA (Dictyostelium discoideum)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB geranylgeranylation (Dictyostelium discoideum)
RGGT geranylgeranylates RAB proteins (Dictyostelium discoideum)
CHMs:GGC-RABs:GDP [cytosol] (Dictyostelium discoideum)
GGC-RABs:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Dictyostelium discoideum)
RABs:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RGGT:CHM binds RABs (Dictyostelium discoideum)
RABs:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Dictyostelium discoideum)
RABs:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Translation (Dictyostelium discoideum)
Eukaryotic Translation Elongation (Dictyostelium discoideum)
Regeneration of eEF1A:GTP by eEF1B activity (Dictyostelium discoideum)
eEF1A:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
eEF1B:GDP exchange complex [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Eukaryotic Translation Initiation (Dictyostelium discoideum)
Cap-dependent Translation Initiation (Dictyostelium discoideum)
GTP hydrolysis and joining of the 60S ribosomal subunit (Dictyostelium discoideum)
eIF5B:GTP is hydrolyzed and released (Dictyostelium discoideum)
eIF5B:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Recycling of eIF2:GDP (Dictyostelium discoideum)
Formation of eIF2:GDP:eIF2B intermediate (Dictyostelium discoideum)
eIF2:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
eIF2 activation (Dictyostelium discoideum)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Neuronal System (Dictyostelium discoideum)
Transmission across Chemical Synapses (Dictyostelium discoideum)
Neurotransmitter receptors and postsynaptic signal transmission (Dictyostelium discoideum)
GABA receptor activation (Dictyostelium discoideum)
GABA B receptor activation (Dictyostelium discoideum)
Activation of GABAB receptors (Dictyostelium discoideum)
Adenylate cyclase inhibitory pathway (Dictyostelium discoideum)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Dictyostelium discoideum)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Dictyostelium discoideum)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Dictyostelium discoideum)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Organelle biogenesis and maintenance (Dictyostelium discoideum)
Cilium Assembly (Dictyostelium discoideum)
Cargo trafficking to the periciliary membrane (Dictyostelium discoideum)
VxPx cargo-targeting to cilium (Dictyostelium discoideum)
GBF1 stimulates nucleotide exchange on ARF4 (Dictyostelium discoideum)
GDP [cytosol]
ARF4:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
HDAC6 deacetylates microtubules (Dictyostelium discoideum)
acetylated microtubule [cytosol] (Dictyostelium discoideum)
acetylated microtubule protofilament [cytosol] (Dictyostelium discoideum)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
microtubule (no TUBA4B) [cytosol] (Dictyostelium discoideum)
Microtubule protofilament (no TUBA4B) [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer (no TUBA4B) [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Signal Transduction (Dictyostelium discoideum)
Death Receptor Signaling (Dictyostelium discoideum)
p75 NTR receptor-mediated signalling (Dictyostelium discoideum)
Cell death signalling via NRAGE, NRIF and NADE (Dictyostelium discoideum)
NRAGE signals death through JNK (Dictyostelium discoideum)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Dictyostelium discoideum)
GDP [cytosol]
Integrin signaling (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Intracellular signaling by second messengers (Dictyostelium discoideum)
PIP3 activates AKT signaling (Dictyostelium discoideum)
PTEN Regulation (Dictyostelium discoideum)
Regulation of PTEN gene transcription (Dictyostelium discoideum)
MAF1 translocates to the nucleus (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
MTOR signalling (Dictyostelium discoideum)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Formation of active mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GTP loading by Rheb (Dictyostelium discoideum)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
GDP [cytosol]
Rag dimer formation (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Ragulator binds Rag dimers (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1-mediated signalling (Dictyostelium discoideum)
Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Dictyostelium discoideum)
RagA,B:GTP:RagC,D:GDP [cytosol] (Dictyostelium discoideum)
RRAGC,RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (i) signalling events (Dictyostelium discoideum)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Dictyostelium discoideum)
G alpha (i):GDP:RGS [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Dictyostelium discoideum)
G alpha (i):GDP:RGS [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Dictyostelium discoideum)
GDP [cytosol]
Opioid Signalling (Dictyostelium discoideum)
G-protein activation (Dictyostelium discoideum)
G-protein alpha subunit is inactivated (Dictyostelium discoideum)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G-protein mediated events (Dictyostelium discoideum)
Adenylate cyclase activating pathway (Dictyostelium discoideum)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Dictyostelium discoideum)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Dictyostelium discoideum)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Dictyostelium discoideum)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Dictyostelium discoideum)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Dictyostelium discoideum)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
PLC beta mediated events (Dictyostelium discoideum)
Inactivation of PLC beta (Dictyostelium discoideum)
G-protein alpha:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha (q) signalling events (Dictyostelium discoideum)
G alpha (q) in G (q):RGS complex is inactivated (Dictyostelium discoideum)
G alpha (q):GDP:RGS [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Dictyostelium discoideum)
G alpha (q):GDP:RGS [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha (z) signalling events (Dictyostelium discoideum)
G alpha (z) in G alpha (z):RGS complex is inactivated (Dictyostelium discoideum)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Dictyostelium discoideum)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Signaling by Hedgehog (Dictyostelium discoideum)
Hedgehog 'off' state (Dictyostelium discoideum)
KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Dictyostelium discoideum)
KIF7:microtubule [ciliary tip] (Dictyostelium discoideum)
microtubule [axonemal microtubule] (Dictyostelium discoideum)
alpha-beta tubulin dimer [axonemal microtubule] (Dictyostelium discoideum)
beta tubulin:GDP [axonemal microtubule] (Dictyostelium discoideum)
GDP [cytosol]
microtubule [axonemal microtubule] (Dictyostelium discoideum)
alpha-beta tubulin dimer [axonemal microtubule] (Dictyostelium discoideum)
beta tubulin:GDP [axonemal microtubule] (Dictyostelium discoideum)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by PTK6 (Dictyostelium discoideum)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Dictyostelium discoideum)
Activation of RAC1 by the PXN:CRK complex (Dictyostelium discoideum)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
Miro GTPase Cycle (Dictyostelium discoideum)
RHOT1 GTPase cycle (Dictyostelium discoideum)
RHOT1 hydrolyzes GTP (Dictyostelium discoideum)
RHOT1:GDP [mitochondrial outer membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOT2 GTPase cycle (Dictyostelium discoideum)
RHOT2 hydrolyzes GTP (Dictyostelium discoideum)
RHOT1:GDP [mitochondrial outer membrane] (Dictyostelium discoideum)
GDP [cytosol]
Signaling by Rho GTPases (Dictyostelium discoideum)
RHO GTPase Effectors (Dictyostelium discoideum)
RHO GTPases activate IQGAPs (Dictyostelium discoideum)
IQGAP1 binds CLIP1 and microtubules (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RHO GTPase cycle (Dictyostelium discoideum)
CDC42 GTPase cycle (Dictyostelium discoideum)
CDC42 GAPs stimulate CDC42 GTPase activity (Dictyostelium discoideum)
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
CDC42 GDIs block activation of CDC42 (Dictyostelium discoideum)
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
CDC42:GDP:CDC42 GDIs [cytosol] (Dictyostelium discoideum)
CDC42:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
CDC42 GEFs activate CDC42 (Dictyostelium discoideum)
GDP [cytosol]
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC1 GTPase cycle (Dictyostelium discoideum)
RAC1 GAPs stimulate RAC1 GTPase activity (Dictyostelium discoideum)
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC1 GDIs block activation of RAC1 (Dictyostelium discoideum)
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC1:GDP:RAC1 GDIs [cytosol] (Dictyostelium discoideum)
RAC1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAC1 GEFs activate RAC1 (Dictyostelium discoideum)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC2 GTPase cycle (Dictyostelium discoideum)
RAC2 GAPs stimulate RAC2 GTPase activity (Dictyostelium discoideum)
RAC2:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC2 GDIs block activation of RAC2 (Dictyostelium discoideum)
ARHGDIA:RAC2:GDP [cytosol] (Dictyostelium discoideum)
RAC2:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC2 GEFs activate RAC2 (Dictyostelium discoideum)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC3 GTPase cycle (Dictyostelium discoideum)
RAC3 GAPs stimulate RAC3 GTPase activity (Dictyostelium discoideum)
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC3 GDIs block activation of RAC3 (Dictyostelium discoideum)
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RAC3:GDP:RAC3 GDIs [cytosol] (Dictyostelium discoideum)
RAC1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAC3 GEFs activate RAC3 (Dictyostelium discoideum)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOG GTPase cycle (Dictyostelium discoideum)
GDIs block activation of RHOG (Dictyostelium discoideum)
RHOG GDIs:RHOG:GDP [cytosol] (Dictyostelium discoideum)
RHOG:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOG GEFs activate RHOG (Dictyostelium discoideum)
GDP [cytosol]
RHOG:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOJ GTPase cycle (Dictyostelium discoideum)
RHOJ GAPs stimulate RHOJ GTPase activity (Dictyostelium discoideum)
RHOJ:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOJ GEFs activate RHOJ (Dictyostelium discoideum)
GDP [cytosol]
RHOJ:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOQ GTPase cycle (Dictyostelium discoideum)
RHOQ GAPs stimulate RHOQ GTPase activity (Dictyostelium discoideum)
RHOQ:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOQ GEFs activate RHOQ (Dictyostelium discoideum)
GDP [cytosol]
RHOQ:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOU GTPase cycle (Dictyostelium discoideum)
Phosphorylated RHOU translocates to the endosome membrane (Dictyostelium discoideum)
p-Y254-RHOU:GDP [endosome membrane] (Dictyostelium discoideum)
GDP [cytosol]
p-Y254-RHOU:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOU auto-activates (Dictyostelium discoideum)
GDP [cytosol]
RHOU:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
RHOV GTPase cycle (Dictyostelium discoideum)
RHOV binds GTP (Dictyostelium discoideum)
GDP [cytosol]
RHOV:GDP [plasma membrane] (Dictyostelium discoideum)
GDP [cytosol]
Vesicle-mediated transport (Dictyostelium discoideum)
Membrane Trafficking (Dictyostelium discoideum)
ER to Golgi Anterograde Transport (Dictyostelium discoideum)
COPI-mediated anterograde transport (Dictyostelium discoideum)
ARFGAPs stimulate ARF GTPase activity (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Dictyostelium discoideum)
Dynein:Dynactin:microtubule [cytosol] (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Dictyostelium discoideum)
Dynein:Dynactin:microtubule [cytosol] (Dictyostelium discoideum)
Microtubule [cytosol] (Dictyostelium discoideum)
Microtubule protofilament [cytosol] (Dictyostelium discoideum)
alpha-beta tubulin dimer [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Dictyostelium discoideum)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
COPII-mediated vesicle transport (Dictyostelium discoideum)
COPII coat binds TRAPPCII and RAB1:GDP (Dictyostelium discoideum)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Loss of SAR1B GTPase (Dictyostelium discoideum)
SAR1B:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Nucleotide exchange on RAB1 (Dictyostelium discoideum)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Dictyostelium discoideum)
GDP [cytosol]
SAR1B:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Dictyostelium discoideum)
Golgi-to-ER retrograde transport (Dictyostelium discoideum)
COPI-dependent Golgi-to-ER retrograde traffic (Dictyostelium discoideum)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
COPI vesicle uncoating at the ER (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GBF1 recruits ARF:GDP to the Golgi (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF (Dictyostelium discoideum)
GDP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Dictyostelium discoideum)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Dictyostelium discoideum)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Dictyostelium discoideum)
RAB18:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Dictyostelium discoideum)
RAB18:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GDP [endoplasmic reticulum membrane] (Dictyostelium discoideum)
RAB18:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Intra-Golgi traffic (Dictyostelium discoideum)
CYTH proteins stimulate ARF1 GTPase activity (Dictyostelium discoideum)
ARF1:GDP:CYTH1,2,3,4 [Golgi membrane] (Dictyostelium discoideum)
Arf1-GDP [Golgi membrane] (Dictyostelium discoideum)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Dictyostelium discoideum)
RAB43 hydrolyses GTP (Dictyostelium discoideum)
RAB43:GDP:USP6NL [trans-Golgi network membrane] (Dictyostelium discoideum)
RAB43:GDP [trans-Golgi network membrane] (Dictyostelium discoideum)
GDP [cytosol]
RIC1:RGP1 recruits RAB6:GDP to the TGN (Dictyostelium discoideum)
RAB6:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Dictyostelium discoideum)
RAB6:GDP [trans-Golgi network membrane] (Dictyostelium discoideum)
GDP [cytosol]
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Dictyostelium discoideum)
GDP [cytosol]
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Dictyostelium discoideum)
RAB6:GDP [trans-Golgi network membrane] (Dictyostelium discoideum)
GDP [cytosol]
Rab regulation of trafficking (Dictyostelium discoideum)
RAB GEFs exchange GTP for GDP on RABs (Dictyostelium discoideum)
DENND1s exchange GTP for GDP on RAB35 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB35:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB35:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Dictyostelium discoideum)
GDP [cytosol]
GCC-RAB12:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB12:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB14:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB14:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB7:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB7:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB13:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB13:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB21:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB21:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB18:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB18:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB5:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB5:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB9:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB9:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB6:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB6:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB1:GDP:GDIs,CHMs [cytosol] (Dictyostelium discoideum)
GGC-RAB1:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB1A:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
GGC-RAB1B:GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
TBC/RABGAPs (Dictyostelium discoideum)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Dictyostelium discoideum)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Dictyostelium discoideum)
GDP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Dictyostelium discoideum)
RAB33:GDP [Golgi membrane] (Dictyostelium discoideum)
GDP [cytosol]
TBC1D2A accelerates GTP hydrolysis by RAB7 (Dictyostelium discoideum)
RAB7A:GDP [lysosomal membrane] (Dictyostelium discoideum)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Dictyostelium discoideum)
trans-Golgi Network Coat Activation (Dictyostelium discoideum)
GDP [cytosol]
Arf1-GDP [cytosol] (Dictyostelium discoideum)
GDP [cytosol]
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Active MTORC1 binds the ULK1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
MTORC1 dissociates from ULK complex (Drosophila melanogaster)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Nuclear Envelope (NE) Reassembly (Drosophila melanogaster)
Postmitotic nuclear pore complex (NPC) reformation (Drosophila melanogaster)
RAN stimulates fusion of nuclear envelope (NE) membranes (Drosophila melanogaster)
RAN:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Drosophila melanogaster)
GDP [cytosol]
RAN:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to starvation (Drosophila melanogaster)
Amino acids regulate mTORC1 (Drosophila melanogaster)
RRAGA,B exchanges GDP for GTP (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGA,B:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGB:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGA,B:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGB:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGA,B:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGB:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GDP:RagC,D:GTP [cytosol] (Drosophila melanogaster)
RRAGA,B:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGB:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGA,B:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGB:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GDP:RagC,D:GTP [cytosol] (Drosophila melanogaster)
RRAGA,B:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGB:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Drosophila melanogaster)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Drosophila melanogaster)
Dynein:Dynactin:microtubule [cytosol] (Drosophila melanogaster)
Microtubule [cytosol] (Drosophila melanogaster)
Microtubule protofilament [cytosol] (Drosophila melanogaster)
alpha-beta tubulin dimer [cytosol] (Drosophila melanogaster)
beta-tubulin:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPH-ephrin mediated repulsion of cells (Drosophila melanogaster)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
EPHA-mediated growth cone collapse (Drosophila melanogaster)
NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
EPHB-mediated forward signaling (Drosophila melanogaster)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Drosophila melanogaster)
HRAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Drosophila melanogaster)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
L1CAM interactions (Drosophila melanogaster)
Recycling pathway of L1 (Drosophila melanogaster)
Formation of clathrin coated vesicle (Drosophila melanogaster)
GDP [cytosol]
Signal transduction by L1 (Drosophila melanogaster)
Activation of Rac1 by VAV2 (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
NCAM signaling for neurite out-growth (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Activation of Cdc42 (Drosophila melanogaster)
GDP [cytosol]
CDC42:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Activation of Rac1 (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Semaphorin interactions (Drosophila melanogaster)
Sema4D in semaphorin signaling (Drosophila melanogaster)
Sema4D induced cell migration and growth-cone collapse (Drosophila melanogaster)
Activation of Rho by LARG and PDZ-RhoGEF (Drosophila melanogaster)
GDP [cytosol]
Drosophila signaling pathways (Drosophila melanogaster)
Insulin receptor mediated signaling (Drosophila melanogaster)
TOR signaling pathway (Drosophila melanogaster)
DRheb is inhibited by the TSC1/2 complex (Drosophila melanogaster)
DRheb-GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
GDP is exchanged for GTP on DRheb (Drosophila melanogaster)
GDP [cytosol]
GEF:DRheb-GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
GEF binds to the inactive DRheb (Drosophila melanogaster)
DRheb-GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
GEF:DRheb-GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Planar Cell Polarity pathway (Drosophila melanogaster)
Activation of Downstream Effectors (Drosophila melanogaster)
RHO1 signalling (Drosophila melanogaster)
RHO1 GTPase cycle (Drosophila melanogaster)
RHO1:GDP complex dissociates from RHOGAPP190 (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHOGAPP190:RHO1:GDP [plasma membrane] (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHO1:GDP complex dissociates from RHOGDI and binds to the plasma membrane (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHOGDI:RHO1:GDP [cytosol] (Drosophila melanogaster)
RHO1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RHOGAPP190 activates GTP hydrolysis by RHO1:GTP (Drosophila melanogaster)
RHOGAPP190:RHO1:GDP [plasma membrane] (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHOGDI binds to and sequesters RHO1:GDP complex to the cytosol (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHOGDI:RHO1:GDP [cytosol] (Drosophila melanogaster)
RHO1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RHOGEF2 binds to RHO1:GDP complex at the plasma membrane (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHOGEF2:RHO1:GDP [plasma membrane] (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RHOGEF2 stimulates nucleotide exchange of RHO1:GDP complex (Drosophila melanogaster)
GDP [cytosol]
RHOGEF2:RHO1:GDP [plasma membrane] (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Drug ADME (Drosophila melanogaster)
Azathioprine ADME (Drosophila melanogaster)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Drosophila melanogaster)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Hemostasis (Drosophila melanogaster)
Factors involved in megakaryocyte development and platelet production (Drosophila melanogaster)
Kinesins (Drosophila melanogaster)
Kinesins move along microtubules consuming ATP (Drosophila melanogaster)
Kinesins:microtubule [cytosol] (Drosophila melanogaster)
Microtubule [cytosol] (Drosophila melanogaster)
Microtubule protofilament [cytosol] (Drosophila melanogaster)
alpha-beta tubulin dimer [cytosol] (Drosophila melanogaster)
beta-tubulin:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)
GDP [cytosol]
VAV1 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
GDP [cytosol]
VAV2 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
GDP [cytosol]
VAV3 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Signal amplification (Drosophila melanogaster)
ADP signalling through P2Y purinoceptor 12 (Drosophila melanogaster)
Gi activation by P2Y purinoceptor 12 (Drosophila melanogaster)
GDP [cytosol]
Thromboxane signalling through TP receptor (Drosophila melanogaster)
G13 activation by TP receptor (Drosophila melanogaster)
GDP [cytosol]
Gq activation by TP receptor (Drosophila melanogaster)
GDP [cytosol]
Platelet homeostasis (Drosophila melanogaster)
Prostacyclin signalling through prostacyclin receptor (Drosophila melanogaster)
Gs activation by prostacyclin receptor (Drosophila melanogaster)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Drosophila melanogaster)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
G alpha (s):GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Rap1 signalling (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Rap1 signal termination by Rap1GAPs (Drosophila melanogaster)
RAP1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Cytokine Signaling in Immune system (Drosophila melanogaster)
FLT3 Signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Innate Immune System (Drosophila melanogaster)
DAP12 interactions (Drosophila melanogaster)
DAP12 signaling (Drosophila melanogaster)
Activation of RAC1 by VAV2/3 (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
Activation of RAC1 by VAV (Drosophila melanogaster)
GDP [cytosol]
Rac1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Metabolism (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Adrenaline,noradrenaline inhibits insulin secretion (Drosophila melanogaster)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Drosophila melanogaster)
GDP [cytosol]
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Drosophila melanogaster)
G-alpha(i,o):GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Drosophila melanogaster)
RAP1A exchanges GDP for GTP (Drosophila melanogaster)
GDP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PCK1 phosphorylates OA to yield PEP (Drosophila melanogaster)
GDP [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Interconversion of nucleotide di- and triphosphates (Drosophila melanogaster)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Drosophila melanogaster)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Drosophila melanogaster)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Drosophila melanogaster)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Drosophila melanogaster)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Drosophila melanogaster)
GDP [cytosol]
Metabolism of RNA (Drosophila melanogaster)
Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Drosophila melanogaster)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Drosophila melanogaster)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
Addition of a second mannose to the N-glycan precursor by ALG2 (Drosophila melanogaster)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Drosophila melanogaster)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Drosophila melanogaster)
ER to Golgi Anterograde Transport (Drosophila melanogaster)
COPI-mediated anterograde transport (Drosophila melanogaster)
ARFGAPs stimulate ARF GTPase activity (Drosophila melanogaster)
ARF:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Drosophila melanogaster)
Dynein:Dynactin:microtubule [cytosol] (Drosophila melanogaster)
Microtubule [cytosol] (Drosophila melanogaster)
Microtubule protofilament [cytosol] (Drosophila melanogaster)
alpha-beta tubulin dimer [cytosol] (Drosophila melanogaster)
beta-tubulin:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Drosophila melanogaster)
Dynein:Dynactin:microtubule [cytosol] (Drosophila melanogaster)
Microtubule [cytosol] (Drosophila melanogaster)
Microtubule protofilament [cytosol] (Drosophila melanogaster)
alpha-beta tubulin dimer [cytosol] (Drosophila melanogaster)
beta-tubulin:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Drosophila melanogaster)
ARF:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
ARF:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Drosophila melanogaster)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
ARF:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
COPII-mediated vesicle transport (Drosophila melanogaster)
COPII coat binds TRAPPCII and RAB1:GDP (Drosophila melanogaster)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
RAB1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RAB1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Loss of SAR1B GTPase (Drosophila melanogaster)
SAR1B:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Nucleotide exchange on RAB1 (Drosophila melanogaster)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
RAB1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Drosophila melanogaster)
GDP [cytosol]
SAR1B:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Drosophila melanogaster)
RAB1:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RAB geranylgeranylation (Drosophila melanogaster)
RGGT geranylgeranylates RAB proteins (Drosophila melanogaster)
CHMs:GGC-RABs:GDP [cytosol] (Drosophila melanogaster)
GGC-RABs:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Drosophila melanogaster)
RABs:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RGGT:CHM binds RABs (Drosophila melanogaster)
RABs:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Drosophila melanogaster)
RABs:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Translation (Drosophila melanogaster)
Eukaryotic Translation Elongation (Drosophila melanogaster)
Regeneration of eEF1A:GTP by eEF1B activity (Drosophila melanogaster)
eEF1A:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
eEF1B:GDP exchange complex [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
GTP hydrolysis and joining of the 60S ribosomal subunit (Drosophila melanogaster)
eIF5B:GTP is hydrolyzed and released (Drosophila melanogaster)
eIF5B:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Recycling of eIF2:GDP (Drosophila melanogaster)
Formation of eIF2:GDP:eIF2B intermediate (Drosophila melanogaster)
eIF2:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Drosophila melanogaster)
GDP [cytosol]
eIF2 activation (Drosophila melanogaster)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
GABA receptor activation (Drosophila melanogaster)
GABA B receptor activation (Drosophila melanogaster)
Activation of GABAB receptors (Drosophila melanogaster)
Adenylate cyclase inhibitory pathway (Drosophila melanogaster)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Drosophila melanogaster)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Drosophila melanogaster)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Drosophila melanogaster)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Organelle biogenesis and maintenance (Drosophila melanogaster)
Cilium Assembly (Drosophila melanogaster)
Cargo trafficking to the periciliary membrane (Drosophila melanogaster)
VxPx cargo-targeting to cilium (Drosophila melanogaster)
ASAP1 stimulates GTPase activity of ARF4 (Drosophila melanogaster)
ARF4:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Drosophila melanogaster)
GDP [cytosol]
ARF4:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Drosophila melanogaster)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Drosophila melanogaster)
RAB8A:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
p75 NTR receptor-mediated signalling (Drosophila melanogaster)
Cell death signalling via NRAGE, NRIF and NADE (Drosophila melanogaster)
NRAGE signals death through JNK (Drosophila melanogaster)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Drosophila melanogaster)
GDP [cytosol]
p75NTR regulates axonogenesis (Drosophila melanogaster)
Axonal growth inhibition (RHOA activation) (Drosophila melanogaster)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Integrin signaling (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN gene transcription (Drosophila melanogaster)
MAF1 translocates to the nucleus (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
RAS processing (Drosophila melanogaster)
mature p21 RAS binds GDP (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Regulation of RAS by GAPs (Drosophila melanogaster)
RAS GAPs stimulate RAS GTPase activity (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
MTOR signalling (Drosophila melanogaster)
AKT1S1 (PRAS40) binds mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Formation of active mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
GTP loading by Rheb (Drosophila melanogaster)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
GDP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Rag dimer formation (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Ragulator binds Rag dimers (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
RagA,B:GTP:RagC,D:GDP [cytosol] (Drosophila melanogaster)
RRAGC,RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
RRAGD:GDP [cytosol] (Drosophila melanogaster)
GDP [cytosol]
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
GEFs activate RhoA,B,C (Drosophila melanogaster)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Drosophila melanogaster)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Drosophila melanogaster)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha (i) signalling events (Drosophila melanogaster)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Drosophila melanogaster)
G alpha (i):GDP:RGS [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Drosophila melanogaster)
G alpha (i):GDP:RGS [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
GDP [cytosol]
Opioid Signalling (Drosophila melanogaster)
G-protein activation (Drosophila melanogaster)
G-protein alpha subunit is inactivated (Drosophila melanogaster)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G-protein beta-gamma subunits rebind the alpha-GDP subunit (Drosophila melanogaster)
G protein-GDP complex [plasma membrane] (Drosophila melanogaster)
G-protein alpha:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Drosophila melanogaster)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Drosophila melanogaster)
G protein-GDP complex [plasma membrane] (Drosophila melanogaster)
G-protein alpha:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G-protein mediated events (Drosophila melanogaster)
Adenylate cyclase activating pathway (Drosophila melanogaster)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Drosophila melanogaster)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Drosophila melanogaster)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Drosophila melanogaster)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Drosophila melanogaster)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Drosophila melanogaster)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
PLC beta mediated events (Drosophila melanogaster)
Inactivation of PLC beta (Drosophila melanogaster)
G-protein alpha:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha (q) signalling events (Drosophila melanogaster)
G alpha (q) in G (q):RGS complex is inactivated (Drosophila melanogaster)
G alpha (q):GDP:RGS [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Drosophila melanogaster)
G alpha (q):GDP:RGS [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
EGFR Transactivation by Gastrin (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
GDP [cytosol]
G alpha (s) signalling events (Drosophila melanogaster)
Liganded Gs-activating GPCR acts as a GEF for Gs (Drosophila melanogaster)
GDP [cytosol]
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Drosophila melanogaster)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
G alpha (s):GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
G alpha (s):GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
G alpha (z) signalling events (Drosophila melanogaster)
Liganded Gz-activating GPCR acts as a GEF for Gz (Drosophila melanogaster)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
ARHGAP35 stimulates RHOA GTPase activity (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Drosophila melanogaster)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Drosophila melanogaster)
GDP [cytosol]
![GDP [cytosol] icon](/icon/R-ICO-012804.svg){kind=icon}