Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
GDP [cytosol]
Stable Identifier
R-ALL-29420
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Guanosine 5'-diphosphate, Guanosine diphosphate, GDP(3-)
Icon
Locations in the PathwayBrowser for interactor UniProt:P62826
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
GDP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Bos taurus)
GDP [cytosol]
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH-ephrin mediated repulsion of cells (Bos taurus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
EPHA-mediated growth cone collapse (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
GDP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
GDP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Formation of clathrin coated vesicle (Bos taurus)
GDP [cytosol]
Signal transduction by L1 (Bos taurus)
Activation of Rac1 by VAV2 (Bos taurus)
GDP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
GDP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Activation of Cdc42 (Bos taurus)
GDP [cytosol]
Activation of Rac1 (Bos taurus)
GDP [cytosol]
Semaphorin interactions (Bos taurus)
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)
GDP [cytosol]
Drug ADME (Bos taurus)
Azathioprine ADME (Bos taurus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Bos taurus)
GDP [cytosol]
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Tie2 Signaling (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
GDP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Bos taurus)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Gi activation by P2Y purinoceptor 12 (Bos taurus)
GDP [cytosol]
Thromboxane signalling through TP receptor (Bos taurus)
G13 activation by TP receptor (Bos taurus)
GDP [cytosol]
Gq activation by TP receptor (Bos taurus)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
Thrombin-activated PARs activate G12/13 (Bos taurus)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Bos taurus)
GDP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Disassembly of COPII coated vesicle (Bos taurus)
GDP [cytosol]
Costimulation by the CD28 family (Bos taurus)
CD28 co-stimulation (Bos taurus)
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Cdc42 by pVav1 (Bos taurus)
GDP [cytosol]
Activation of Rac1 by pVav1 (Bos taurus)
GDP [cytosol]
MHC class II antigen presentation (Bos taurus)
Internalization of MHC II:Ii clathrin coated vesicle (Bos taurus)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Bos taurus)
GDP [cytosol]
Rap1 signalling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
GDP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
GDP [cytosol]
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
Activation of RAC1 by VAV2/3 (Bos taurus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
GDP [cytosol]
Activation of RAC1 by VAV (Bos taurus)
GDP [cytosol]
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)
RAP1A exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PCK1 phosphorylates OA to yield PEP (Bos taurus)
GDP [cytosol]
Metabolism of nucleotides (Bos taurus)
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
GDP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Bos taurus)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Bos taurus)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
Synthesis of dolichyl-phosphate mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPII-mediated vesicle transport (Bos taurus)
Nucleotide exchange on RAB1 (Bos taurus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Bos taurus)
Synthesis of dolichyl-phosphate mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
GDP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
Recycling of eIF2:GDP (Bos taurus)
eIF2 activation (Bos taurus)
GDP [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
Anchoring of the basal body to the plasma membrane (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Bos taurus)
VxPx cargo-targeting to cilium (Bos taurus)
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GDP [cytosol]
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
p75 NTR receptor-mediated signalling (Bos taurus)
Cell death signalling via NRAGE, NRIF and NADE (Bos taurus)
NRAGE signals death through JNK (Bos taurus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)
GDP [cytosol]
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Intrinsic nucleotide exchange on RAS (Bos taurus)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
RAS processing (Bos taurus)
mature p21 RAS binds GDP (Bos taurus)
GDP [cytosol]
MTOR signalling (Bos taurus)
GTP loading by Rheb (Bos taurus)
GDP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
GEFs activate RhoA,B,C (Bos taurus)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Bos taurus)
GDP [cytosol]
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
GDP [cytosol]
Opioid Signalling (Bos taurus)
G-protein activation (Bos taurus)
G-protein alpha subunit is inactivated (Bos taurus)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Bos taurus)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Bos taurus)
GDP [cytosol]
G alpha (q) signalling events (Bos taurus)
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
EGFR Transactivation by Gastrin (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
GDP [cytosol]
G alpha (s) signalling events (Bos taurus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
GDP [cytosol]
G alpha (z) signalling events (Bos taurus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
Activation of RAC1 by the PXN:CRK complex (Bos taurus)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
GRB2 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
GDP [cytosol]
SHC1 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
GDP [cytosol]
Signaling by ERBB2 (Bos taurus)
GRB2 events in ERBB2 signaling (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
GDP [cytosol]
Signaling by ERBB4 (Bos taurus)
SHC1 events in ERBB4 signaling (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
GDP [cytosol]
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
Signaling by MET (Bos taurus)
MET activates RAS signaling (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
GDP [cytosol]
MET promotes cell motility (Bos taurus)
MET activates RAP1 and RAC1 (Bos taurus)
DOCK7 activates RAC1 (Bos taurus)
GDP [cytosol]
RAPGEF1 activates RAP1 (Bos taurus)
GDP [cytosol]
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
ARMS-mediated activation (Bos taurus)
C3G stimulates nucleotide exchange on Rap1 (Bos taurus)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Bos taurus)
Activated NTRK2 signals through FYN (Bos taurus)
NTRK2 activates RAC1 (Bos taurus)
DOCK3 activates RAC1 (Bos taurus)
GDP [cytosol]
Signaling by PDGF (Bos taurus)
Downstream signal transduction (Bos taurus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)
GDP [cytosol]
Signaling by SCF-KIT (Bos taurus)
Activation of RAC1 (Bos taurus)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
GDP [cytosol]
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase cycle (Bos taurus)
CDC42 GTPase cycle (Bos taurus)
CDC42 GEFs activate CDC42 (Bos taurus)
GDP [cytosol]
RAC1 GTPase cycle (Bos taurus)
RAC1 GEFs activate RAC1 (Bos taurus)
GDP [cytosol]
RAC2 GTPase cycle (Bos taurus)
RAC2 GEFs activate RAC2 (Bos taurus)
GDP [cytosol]
RAC3 GTPase cycle (Bos taurus)
RAC3 GEFs activate RAC3 (Bos taurus)
GDP [cytosol]
RHOA GTPase cycle (Bos taurus)
RHOA GEFs activate RHOA (Bos taurus)
GDP [cytosol]
RHOC GTPase cycle (Bos taurus)
RHOC GEFs activate RHOC (Bos taurus)
GDP [cytosol]
RHOD GTPase cycle (Bos taurus)
RHOD auto-activates (Bos taurus)
GDP [cytosol]
RHOF GTPase cycle (Bos taurus)
RHOF auto-activates (Bos taurus)
GDP [cytosol]
RHOG GTPase cycle (Bos taurus)
RHOG GEFs activate RHOG (Bos taurus)
GDP [cytosol]
RHOJ GTPase cycle (Bos taurus)
RHOJ GEFs activate RHOJ (Bos taurus)
GDP [cytosol]
RHOQ GTPase cycle (Bos taurus)
RHOQ GEFs activate RHOQ (Bos taurus)
GDP [cytosol]
RHOU GTPase cycle (Bos taurus)
RHOU auto-activates (Bos taurus)
GDP [cytosol]
RHOV GTPase cycle (Bos taurus)
RHOV binds GTP (Bos taurus)
GDP [cytosol]
Signaling by WNT (Bos taurus)
Beta-catenin independent WNT signaling (Bos taurus)
Ca2+ pathway (Bos taurus)
WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)
GDP [cytosol]
Transport of small molecules (Bos taurus)
Aquaporin-mediated transport (Bos taurus)
Vasopressin regulates renal water homeostasis via Aquaporins (Bos taurus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPII-mediated vesicle transport (Bos taurus)
Nucleotide exchange on RAB1 (Bos taurus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-dependent Golgi-to-ER retrograde traffic (Bos taurus)
GBF1 stimulates nucleotide exchange on ARF (Bos taurus)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Bos taurus)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Bos taurus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Bos taurus)
GDP [cytosol]
Rab regulation of trafficking (Bos taurus)
RAB GEFs exchange GTP for GDP on RABs (Bos taurus)
DENND1s exchange GTP for GDP on RAB35 (Bos taurus)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Bos taurus)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Bos taurus)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Bos taurus)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Bos taurus)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Bos taurus)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Bos taurus)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Bos taurus)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Bos taurus)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Bos taurus)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Bos taurus)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Bos taurus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Bos taurus)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Bos taurus)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Bos taurus)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Bos taurus)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Bos taurus)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Bos taurus)
Golgi Associated Vesicle Biogenesis (Bos taurus)
trans-Golgi Network Vesicle Scission (Bos taurus)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Bos taurus)
trans-Golgi Network Lysosomal Vesicle Scission (Bos taurus)
GDP [cytosol]
trans-Golgi Network Coat Activation (Bos taurus)
GDP [cytosol]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Metaphase and Anaphase (Caenorhabditis elegans)
Mitotic Anaphase (Caenorhabditis elegans)
Nuclear Envelope (NE) Reassembly (Caenorhabditis elegans)
Postmitotic nuclear pore complex (NPC) reformation (Caenorhabditis elegans)
RCC1 stimulates GDP to GTP exchange on RAN (Caenorhabditis elegans)
GDP [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to starvation (Caenorhabditis elegans)
Amino acids regulate mTORC1 (Caenorhabditis elegans)
RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)
GDP [cytosol]
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
EPH-Ephrin signaling (Caenorhabditis elegans)
EPH-ephrin mediated repulsion of cells (Caenorhabditis elegans)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
EPHA-mediated growth cone collapse (Caenorhabditis elegans)
NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)
GDP [cytosol]
EPHB-mediated forward signaling (Caenorhabditis elegans)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Caenorhabditis elegans)
GDP [cytosol]
L1CAM interactions (Caenorhabditis elegans)
Recycling pathway of L1 (Caenorhabditis elegans)
Formation of clathrin coated vesicle (Caenorhabditis elegans)
GDP [cytosol]
Signal transduction by L1 (Caenorhabditis elegans)
Activation of Rac1 by VAV2 (Caenorhabditis elegans)
GDP [cytosol]
NCAM signaling for neurite out-growth (Caenorhabditis elegans)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Caenorhabditis elegans)
GDP [cytosol]
Netrin-1 signaling (Caenorhabditis elegans)
DCC mediated attractive signaling (Caenorhabditis elegans)
Activation of Cdc42 (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rac1 (Caenorhabditis elegans)
GDP [cytosol]
Semaphorin interactions (Caenorhabditis elegans)
Sema4D in semaphorin signaling (Caenorhabditis elegans)
Sema4D induced cell migration and growth-cone collapse (Caenorhabditis elegans)
Activation of Rho by LARG and PDZ-RhoGEF (Caenorhabditis elegans)
GDP [cytosol]
Drug ADME (Caenorhabditis elegans)
Azathioprine ADME (Caenorhabditis elegans)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Caenorhabditis elegans)
GDP [cytosol]
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
GPVI-mediated activation cascade (Caenorhabditis elegans)
VAV1 is a GEF for Rho/Rac family GTPases (Caenorhabditis elegans)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GDP [cytosol]
Signal amplification (Caenorhabditis elegans)
ADP signalling through P2Y purinoceptor 12 (Caenorhabditis elegans)
Gi activation by P2Y purinoceptor 12 (Caenorhabditis elegans)
GDP [cytosol]
Thromboxane signalling through TP receptor (Caenorhabditis elegans)
G13 activation by TP receptor (Caenorhabditis elegans)
GDP [cytosol]
Gq activation by TP receptor (Caenorhabditis elegans)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Caenorhabditis elegans)
Thrombin-activated PARs activate G12/13 (Caenorhabditis elegans)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Caenorhabditis elegans)
GDP [cytosol]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Rap1 signalling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Caenorhabditis elegans)
Downstream signaling events of B Cell Receptor (BCR) (Caenorhabditis elegans)
Activation of RAS in B cells (Caenorhabditis elegans)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Caenorhabditis elegans)
GDP [cytosol]
Cytokine Signaling in Immune system (Caenorhabditis elegans)
FLT3 Signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)
GDP [cytosol]
Metabolism (Caenorhabditis elegans)
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Adrenaline,noradrenaline inhibits insulin secretion (Caenorhabditis elegans)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Caenorhabditis elegans)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Caenorhabditis elegans)
RAP1A exchanges GDP for GTP (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PCK1 phosphorylates OA to yield PEP (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)
GDP [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
Addition of a second mannose to the N-glycan precursor by ALG2 (Caenorhabditis elegans)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Caenorhabditis elegans)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPII-mediated vesicle transport (Caenorhabditis elegans)
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
GDP [cytosol]
Translation (Caenorhabditis elegans)
Eukaryotic Translation Initiation (Caenorhabditis elegans)
Cap-dependent Translation Initiation (Caenorhabditis elegans)
Recycling of eIF2:GDP (Caenorhabditis elegans)
eIF2 activation (Caenorhabditis elegans)
GDP [cytosol]
Organelle biogenesis and maintenance (Caenorhabditis elegans)
Cilium Assembly (Caenorhabditis elegans)
Cargo trafficking to the periciliary membrane (Caenorhabditis elegans)
VxPx cargo-targeting to cilium (Caenorhabditis elegans)
RAB3IP stimulates nucleotide exchange on RAB8A (Caenorhabditis elegans)
GDP [cytosol]
Signal Transduction (Caenorhabditis elegans)
Death Receptor Signaling (Caenorhabditis elegans)
p75 NTR receptor-mediated signalling (Caenorhabditis elegans)
Cell death signalling via NRAGE, NRIF and NADE (Caenorhabditis elegans)
NRAGE signals death through JNK (Caenorhabditis elegans)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)
GDP [cytosol]
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GDP [cytosol]
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
Intrinsic nucleotide exchange on RAS (Caenorhabditis elegans)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
RAS processing (Caenorhabditis elegans)
mature p21 RAS binds GDP (Caenorhabditis elegans)
GDP [cytosol]
MTOR signalling (Caenorhabditis elegans)
GTP loading by Rheb (Caenorhabditis elegans)
GDP [cytosol]
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (12/13) signalling events (Caenorhabditis elegans)
GEFs activate RhoA,B,C (Caenorhabditis elegans)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Caenorhabditis elegans)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Caenorhabditis elegans)
GDP [cytosol]
G alpha (i) signalling events (Caenorhabditis elegans)
Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
GDP [cytosol]
Opioid Signalling (Caenorhabditis elegans)
G-protein activation (Caenorhabditis elegans)
G-protein alpha subunit is inactivated (Caenorhabditis elegans)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Caenorhabditis elegans)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Caenorhabditis elegans)
GDP [cytosol]
G alpha (q) signalling events (Caenorhabditis elegans)
Gastrin-CREB signalling pathway via PKC and MAPK (Caenorhabditis elegans)
EGFR Transactivation by Gastrin (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Caenorhabditis elegans)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)
GDP [cytosol]
G alpha (s) signalling events (Caenorhabditis elegans)
Liganded Gs-activating GPCR acts as a GEF for Gs (Caenorhabditis elegans)
GDP [cytosol]
G alpha (z) signalling events (Caenorhabditis elegans)
Liganded Gz-activating GPCR acts as a GEF for Gz (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by PTK6 (Caenorhabditis elegans)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Caenorhabditis elegans)
Activation of RAC1 by the PXN:CRK complex (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by EGFR (Caenorhabditis elegans)
GRB2 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)
GDP [cytosol]
SHC1 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)
GDP [cytosol]
Signaling by ERBB2 (Caenorhabditis elegans)
GRB2 events in ERBB2 signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR (Caenorhabditis elegans)
Signaling by FGFR1 (Caenorhabditis elegans)
Downstream signaling of activated FGFR1 (Caenorhabditis elegans)
FRS-mediated FGFR1 signaling (Caenorhabditis elegans)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Caenorhabditis elegans)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR2 (Caenorhabditis elegans)
Downstream signaling of activated FGFR2 (Caenorhabditis elegans)
FRS-mediated FGFR2 signaling (Caenorhabditis elegans)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Caenorhabditis elegans)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR3 (Caenorhabditis elegans)
Downstream signaling of activated FGFR3 (Caenorhabditis elegans)
FRS-mediated FGFR3 signaling (Caenorhabditis elegans)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Caenorhabditis elegans)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
Signaling by FGFR4 (Caenorhabditis elegans)
Downstream signaling of activated FGFR4 (Caenorhabditis elegans)
FRS-mediated FGFR4 signaling (Caenorhabditis elegans)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Caenorhabditis elegans)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
Signaling by MET (Caenorhabditis elegans)
MET activates RAS signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Caenorhabditis elegans)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Caenorhabditis elegans)
GDP [cytosol]
MET promotes cell motility (Caenorhabditis elegans)
MET activates RAP1 and RAC1 (Caenorhabditis elegans)
DOCK7 activates RAC1 (Caenorhabditis elegans)
GDP [cytosol]
RAPGEF1 activates RAP1 (Caenorhabditis elegans)
GDP [cytosol]
Signaling by PDGF (Caenorhabditis elegans)
Downstream signal transduction (Caenorhabditis elegans)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
GDP [cytosol]
Signaling by SCF-KIT (Caenorhabditis elegans)
Activation of RAC1 (Caenorhabditis elegans)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Caenorhabditis elegans)
GDP [cytosol]
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
Signaling by Rho GTPases (Caenorhabditis elegans)
RHO GTPase cycle (Caenorhabditis elegans)
CDC42 GTPase cycle (Caenorhabditis elegans)
CDC42 GEFs activate CDC42 (Caenorhabditis elegans)
GDP [cytosol]
RAC1 GTPase cycle (Caenorhabditis elegans)
RAC1 GEFs activate RAC1 (Caenorhabditis elegans)
GDP [cytosol]
RAC2 GTPase cycle (Caenorhabditis elegans)
RAC2 GEFs activate RAC2 (Caenorhabditis elegans)
GDP [cytosol]
RAC3 GTPase cycle (Caenorhabditis elegans)
RAC3 GEFs activate RAC3 (Caenorhabditis elegans)
GDP [cytosol]
RHOA GTPase cycle (Caenorhabditis elegans)
RHOA GEFs activate RHOA (Caenorhabditis elegans)
GDP [cytosol]
RHOB GTPase cycle (Caenorhabditis elegans)
RHOB GEFs activate RHOB (Caenorhabditis elegans)
GDP [cytosol]
RHOD GTPase cycle (Caenorhabditis elegans)
RHOD auto-activates (Caenorhabditis elegans)
GDP [cytosol]
RHOF GTPase cycle (Caenorhabditis elegans)
RHOF auto-activates (Caenorhabditis elegans)
GDP [cytosol]
RHOG GTPase cycle (Caenorhabditis elegans)
RHOG GEFs activate RHOG (Caenorhabditis elegans)
GDP [cytosol]
RHOJ GTPase cycle (Caenorhabditis elegans)
RHOJ GEFs activate RHOJ (Caenorhabditis elegans)
GDP [cytosol]
RHOQ GTPase cycle (Caenorhabditis elegans)
RHOQ GEFs activate RHOQ (Caenorhabditis elegans)
GDP [cytosol]
RHOU GTPase cycle (Caenorhabditis elegans)
RHOU auto-activates (Caenorhabditis elegans)
GDP [cytosol]
RHOV GTPase cycle (Caenorhabditis elegans)
RHOV binds GTP (Caenorhabditis elegans)
GDP [cytosol]
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
Ca2+ pathway (Caenorhabditis elegans)
WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPII-mediated vesicle transport (Caenorhabditis elegans)
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
Golgi-to-ER retrograde transport (Caenorhabditis elegans)
COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Caenorhabditis elegans)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Caenorhabditis elegans)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)
GDP [cytosol]
Rab regulation of trafficking (Caenorhabditis elegans)
RAB GEFs exchange GTP for GDP on RABs (Caenorhabditis elegans)
DENND1s exchange GTP for GDP on RAB35 (Caenorhabditis elegans)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Caenorhabditis elegans)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Caenorhabditis elegans)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Caenorhabditis elegans)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Caenorhabditis elegans)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Caenorhabditis elegans)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Caenorhabditis elegans)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Caenorhabditis elegans)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Caenorhabditis elegans)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Caenorhabditis elegans)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Caenorhabditis elegans)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Caenorhabditis elegans)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Caenorhabditis elegans)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Caenorhabditis elegans)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Caenorhabditis elegans)
Golgi Associated Vesicle Biogenesis (Caenorhabditis elegans)
trans-Golgi Network Vesicle Scission (Caenorhabditis elegans)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Caenorhabditis elegans)
trans-Golgi Network Lysosomal Vesicle Scission (Caenorhabditis elegans)
GDP [cytosol]
trans-Golgi Network Coat Activation (Caenorhabditis elegans)
GDP [cytosol]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Nuclear Envelope (NE) Reassembly (Canis familiaris)
Postmitotic nuclear pore complex (NPC) reformation (Canis familiaris)
RCC1 stimulates GDP to GTP exchange on RAN (Canis familiaris)
GDP [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to starvation (Canis familiaris)
Amino acids regulate mTORC1 (Canis familiaris)
RRAGA,B exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Canis familiaris)
GDP [cytosol]
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPH-ephrin mediated repulsion of cells (Canis familiaris)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
EPHA-mediated growth cone collapse (Canis familiaris)
NGEF exchanges GTP for GDP on RHOA (Canis familiaris)
GDP [cytosol]
EPHB-mediated forward signaling (Canis familiaris)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Canis familiaris)
GDP [cytosol]
L1CAM interactions (Canis familiaris)
Recycling pathway of L1 (Canis familiaris)
Formation of clathrin coated vesicle (Canis familiaris)
GDP [cytosol]
Signal transduction by L1 (Canis familiaris)
Activation of Rac1 by VAV2 (Canis familiaris)
GDP [cytosol]
NCAM signaling for neurite out-growth (Canis familiaris)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Canis familiaris)
GDP [cytosol]
Netrin-1 signaling (Canis familiaris)
DCC mediated attractive signaling (Canis familiaris)
Activation of Cdc42 (Canis familiaris)
GDP [cytosol]
Activation of Rac1 (Canis familiaris)
GDP [cytosol]
Semaphorin interactions (Canis familiaris)
Sema4D in semaphorin signaling (Canis familiaris)
Sema4D induced cell migration and growth-cone collapse (Canis familiaris)
Activation of Rho by LARG and PDZ-RhoGEF (Canis familiaris)
GDP [cytosol]
Drug ADME (Canis familiaris)
Azathioprine ADME (Canis familiaris)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Canis familiaris)
GDP [cytosol]
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
Tie2 Signaling (Canis familiaris)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Canis familiaris)
GDP [cytosol]
Platelet activation, signaling and aggregation (Canis familiaris)
GPVI-mediated activation cascade (Canis familiaris)
VAV1 is a GEF for Rho/Rac family GTPases (Canis familiaris)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Canis familiaris)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Canis familiaris)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Canis familiaris)
Integrin signaling (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
GDP [cytosol]
Signal amplification (Canis familiaris)
ADP signalling through P2Y purinoceptor 12 (Canis familiaris)
Gi activation by P2Y purinoceptor 12 (Canis familiaris)
GDP [cytosol]
Thromboxane signalling through TP receptor (Canis familiaris)
G13 activation by TP receptor (Canis familiaris)
GDP [cytosol]
Gq activation by TP receptor (Canis familiaris)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Canis familiaris)
Thrombin-activated PARs activate G12/13 (Canis familiaris)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Canis familiaris)
GDP [cytosol]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Class I MHC mediated antigen processing & presentation (Canis familiaris)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Canis familiaris)
Disassembly of COPII coated vesicle (Canis familiaris)
GDP [cytosol]
Costimulation by the CD28 family (Canis familiaris)
CD28 co-stimulation (Canis familiaris)
CD28 dependent Vav1 pathway (Canis familiaris)
Activation of Cdc42 by pVav1 (Canis familiaris)
GDP [cytosol]
Activation of Rac1 by pVav1 (Canis familiaris)
GDP [cytosol]
MHC class II antigen presentation (Canis familiaris)
Internalization of MHC II:Ii clathrin coated vesicle (Canis familiaris)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Canis familiaris)
GDP [cytosol]
Rap1 signalling (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of RAS in B cells (Canis familiaris)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Canis familiaris)
GDP [cytosol]
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)
GDP [cytosol]
Innate Immune System (Canis familiaris)
DAP12 interactions (Canis familiaris)
DAP12 signaling (Canis familiaris)
Activation of RAC1 by VAV2/3 (Canis familiaris)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated MAPK activation (Canis familiaris)
Activation of RAC1 by VAV (Canis familiaris)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
Activation of RAC1 by CRKII:DOCK180:ELMO (Canis familiaris)
GDP [cytosol]
Activation of RAC1 by VAV (Canis familiaris)
GDP [cytosol]
Metabolism (Canis familiaris)
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Adrenaline,noradrenaline inhibits insulin secretion (Canis familiaris)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Canis familiaris)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Canis familiaris)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Canis familiaris)
FFAR1:FFAR1 ligands activate Gq (Canis familiaris)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Canis familiaris)
RAP1A exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PCK1 phosphorylates OA to yield PEP (Canis familiaris)
GDP [cytosol]
Metabolism of nucleotides (Canis familiaris)
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)
GDP [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
Addition of a second mannose to the N-glycan precursor by ALG2 (Canis familiaris)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Canis familiaris)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPII-mediated vesicle transport (Canis familiaris)
Nucleotide exchange on RAB1 (Canis familiaris)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Canis familiaris)
GDP [cytosol]
Translation (Canis familiaris)
Eukaryotic Translation Initiation (Canis familiaris)
Cap-dependent Translation Initiation (Canis familiaris)
Recycling of eIF2:GDP (Canis familiaris)
eIF2 activation (Canis familiaris)
GDP [cytosol]
Organelle biogenesis and maintenance (Canis familiaris)
Cilium Assembly (Canis familiaris)
Anchoring of the basal body to the plasma membrane (Canis familiaris)
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Canis familiaris)
VxPx cargo-targeting to cilium (Canis familiaris)
GBF1 stimulates nucleotide exchange on ARF4 (Canis familiaris)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
GDP [cytosol]
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
p75 NTR receptor-mediated signalling (Canis familiaris)
Cell death signalling via NRAGE, NRIF and NADE (Canis familiaris)
NRAGE signals death through JNK (Canis familiaris)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Canis familiaris)
GDP [cytosol]
Integrin signaling (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
GDP [cytosol]
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
Intrinsic nucleotide exchange on RAS (Canis familiaris)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
RAS processing (Canis familiaris)
mature p21 RAS binds GDP (Canis familiaris)
GDP [cytosol]
MTOR signalling (Canis familiaris)
GTP loading by Rheb (Canis familiaris)
GDP [cytosol]
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (12/13) signalling events (Canis familiaris)
GEFs activate RhoA,B,C (Canis familiaris)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Canis familiaris)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Canis familiaris)
GDP [cytosol]
G alpha (i) signalling events (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
GDP [cytosol]
Opioid Signalling (Canis familiaris)
G-protein activation (Canis familiaris)
G-protein alpha subunit is inactivated (Canis familiaris)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Canis familiaris)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Canis familiaris)
GDP [cytosol]
G alpha (q) signalling events (Canis familiaris)
Gastrin-CREB signalling pathway via PKC and MAPK (Canis familiaris)
EGFR Transactivation by Gastrin (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
GDP [cytosol]
G alpha (s) signalling events (Canis familiaris)
GPER1 signaling (Canis familiaris)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Canis familiaris)
GDP [cytosol]
G alpha (z) signalling events (Canis familiaris)
Liganded Gz-activating GPCR acts as a GEF for Gz (Canis familiaris)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Canis familiaris)
Signaling by PTK6 (Canis familiaris)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Canis familiaris)
Activation of RAC1 by the PXN:CRK complex (Canis familiaris)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by EGFR (Canis familiaris)
GRB2 events in EGFR signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Canis familiaris)
GDP [cytosol]
SHC1 events in EGFR signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Canis familiaris)
GDP [cytosol]
Signaling by ERBB2 (Canis familiaris)
GRB2 events in ERBB2 signaling (Canis familiaris)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)
GDP [cytosol]
Signaling by ERBB4 (Canis familiaris)
SHC1 events in ERBB4 signaling (Canis familiaris)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Canis familiaris)
GDP [cytosol]
Signaling by FGFR (Canis familiaris)
Signaling by FGFR1 (Canis familiaris)
Downstream signaling of activated FGFR1 (Canis familiaris)
FRS-mediated FGFR1 signaling (Canis familiaris)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Canis familiaris)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Signaling by FGFR2 (Canis familiaris)
Downstream signaling of activated FGFR2 (Canis familiaris)
FRS-mediated FGFR2 signaling (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Canis familiaris)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Signaling by FGFR3 (Canis familiaris)
Downstream signaling of activated FGFR3 (Canis familiaris)
FRS-mediated FGFR3 signaling (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Canis familiaris)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
FRS-mediated FGFR4 signaling (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Canis familiaris)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
GDP [cytosol]
Signaling by MET (Canis familiaris)
MET activates RAS signaling (Canis familiaris)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Canis familiaris)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Canis familiaris)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Canis familiaris)
GDP [cytosol]
MET promotes cell motility (Canis familiaris)
MET activates RAP1 and RAC1 (Canis familiaris)
DOCK7 activates RAC1 (Canis familiaris)
GDP [cytosol]
RAPGEF1 activates RAP1 (Canis familiaris)
GDP [cytosol]
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
ARMS-mediated activation (Canis familiaris)
C3G stimulates nucleotide exchange on Rap1 (Canis familiaris)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Canis familiaris)
Activated NTRK2 signals through FYN (Canis familiaris)
NTRK2 activates RAC1 (Canis familiaris)
DOCK3 activates RAC1 (Canis familiaris)
GDP [cytosol]
Signaling by PDGF (Canis familiaris)
Downstream signal transduction (Canis familiaris)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Canis familiaris)
GDP [cytosol]
Signaling by SCF-KIT (Canis familiaris)
Activation of RAC1 (Canis familiaris)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Canis familiaris)
GDP [cytosol]
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Canis familiaris)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
CDC42 GTPase cycle (Canis familiaris)
CDC42 GEFs activate CDC42 (Canis familiaris)
GDP [cytosol]
RAC1 GTPase cycle (Canis familiaris)
RAC1 GEFs activate RAC1 (Canis familiaris)
GDP [cytosol]
RAC2 GTPase cycle (Canis familiaris)
RAC2 GEFs activate RAC2 (Canis familiaris)
GDP [cytosol]
RAC3 GTPase cycle (Canis familiaris)
RAC3 GEFs activate RAC3 (Canis familiaris)
GDP [cytosol]
RHOA GTPase cycle (Canis familiaris)
RHOA GEFs activate RHOA (Canis familiaris)
GDP [cytosol]
RHOB GTPase cycle (Canis familiaris)
RHOB GEFs activate RHOB (Canis familiaris)
GDP [cytosol]
RHOC GTPase cycle (Canis familiaris)
RHOC GEFs activate RHOC (Canis familiaris)
GDP [cytosol]
RHOD GTPase cycle (Canis familiaris)
RHOD auto-activates (Canis familiaris)
GDP [cytosol]
RHOF GTPase cycle (Canis familiaris)
RHOF auto-activates (Canis familiaris)
GDP [cytosol]
RHOG GTPase cycle (Canis familiaris)
RHOG GEFs activate RHOG (Canis familiaris)
GDP [cytosol]
RHOJ GTPase cycle (Canis familiaris)
RHOJ GEFs activate RHOJ (Canis familiaris)
GDP [cytosol]
RHOQ GTPase cycle (Canis familiaris)
RHOQ GEFs activate RHOQ (Canis familiaris)
GDP [cytosol]
RHOU GTPase cycle (Canis familiaris)
RHOU auto-activates (Canis familiaris)
GDP [cytosol]
RHOV GTPase cycle (Canis familiaris)
RHOV binds GTP (Canis familiaris)
GDP [cytosol]
Signaling by WNT (Canis familiaris)
Beta-catenin independent WNT signaling (Canis familiaris)
Ca2+ pathway (Canis familiaris)
WNT:FZD complex promotes G-protein nucleotide exchange (Canis familiaris)
GDP [cytosol]
Transport of small molecules (Canis familiaris)
Aquaporin-mediated transport (Canis familiaris)
Vasopressin regulates renal water homeostasis via Aquaporins (Canis familiaris)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Canis familiaris)
GDP [cytosol]
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPII-mediated vesicle transport (Canis familiaris)
Nucleotide exchange on RAB1 (Canis familiaris)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Canis familiaris)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
Golgi-to-ER retrograde transport (Canis familiaris)
COPI-dependent Golgi-to-ER retrograde traffic (Canis familiaris)
GBF1 stimulates nucleotide exchange on ARF (Canis familiaris)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Canis familiaris)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Canis familiaris)
GDP [cytosol]
Rab regulation of trafficking (Canis familiaris)
RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
DENND1s exchange GTP for GDP on RAB35 (Canis familiaris)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Canis familiaris)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Canis familiaris)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Canis familiaris)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Canis familiaris)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Canis familiaris)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Canis familiaris)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Canis familiaris)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Canis familiaris)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Canis familiaris)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Canis familiaris)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Canis familiaris)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Canis familiaris)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Canis familiaris)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Canis familiaris)
Golgi Associated Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Vesicle Scission (Canis familiaris)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Lysosomal Vesicle Scission (Canis familiaris)
GDP [cytosol]
trans-Golgi Network Coat Activation (Canis familiaris)
GDP [cytosol]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Metaphase and Anaphase (Danio rerio)
Mitotic Anaphase (Danio rerio)
Nuclear Envelope (NE) Reassembly (Danio rerio)
Postmitotic nuclear pore complex (NPC) reformation (Danio rerio)
RCC1 stimulates GDP to GTP exchange on RAN (Danio rerio)
GDP [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to starvation (Danio rerio)
Amino acids regulate mTORC1 (Danio rerio)
RRAGA,B exchanges GDP for GTP (Danio rerio)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Danio rerio)
GDP [cytosol]
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPH-ephrin mediated repulsion of cells (Danio rerio)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Danio rerio)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
GDP [cytosol]
EPHA-mediated growth cone collapse (Danio rerio)
NGEF exchanges GTP for GDP on RHOA (Danio rerio)
GDP [cytosol]
Netrin-1 signaling (Danio rerio)
DCC mediated attractive signaling (Danio rerio)
Activation of Cdc42 (Danio rerio)
GDP [cytosol]
Activation of Rac1 (Danio rerio)
GDP [cytosol]
Semaphorin interactions (Danio rerio)
Sema4D in semaphorin signaling (Danio rerio)
Sema4D induced cell migration and growth-cone collapse (Danio rerio)
Activation of Rho by LARG and PDZ-RhoGEF (Danio rerio)
GDP [cytosol]
Hemostasis (Danio rerio)
Cell surface interactions at the vascular wall (Danio rerio)
Tie2 Signaling (Danio rerio)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Danio rerio)
GDP [cytosol]
Platelet activation, signaling and aggregation (Danio rerio)
Signal amplification (Danio rerio)
ADP signalling through P2Y purinoceptor 12 (Danio rerio)
Gi activation by P2Y purinoceptor 12 (Danio rerio)
GDP [cytosol]
Thromboxane signalling through TP receptor (Danio rerio)
G13 activation by TP receptor (Danio rerio)
GDP [cytosol]
Gq activation by TP receptor (Danio rerio)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Danio rerio)
Thrombin-activated PARs activate G12/13 (Danio rerio)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Danio rerio)
GDP [cytosol]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
MHC class II antigen presentation (Danio rerio)
Translocation of TGN-lysosome vesicle to lysosome (Danio rerio)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of RAS in B cells (Danio rerio)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Danio rerio)
GDP [cytosol]
Metabolism (Danio rerio)
Integration of energy metabolism (Danio rerio)
Regulation of insulin secretion (Danio rerio)
Adrenaline,noradrenaline inhibits insulin secretion (Danio rerio)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Danio rerio)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Danio rerio)
RAP1A exchanges GDP for GTP (Danio rerio)
GDP [cytosol]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PCK1 phosphorylates OA to yield PEP (Danio rerio)
GDP [cytosol]
Metabolism of nucleotides (Danio rerio)
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Danio rerio)
GDP [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
Addition of the first mannose to the N-glycan precursor by ALG1 (Danio rerio)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Danio rerio)
Synthesis of dolichyl-phosphate mannose (Danio rerio)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Danio rerio)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Danio rerio)
ER to Golgi Anterograde Transport (Danio rerio)
COPII-mediated vesicle transport (Danio rerio)
Nucleotide exchange on RAB1 (Danio rerio)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Danio rerio)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Danio rerio)
Synthesis of dolichyl-phosphate mannose (Danio rerio)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Danio rerio)
GDP [cytosol]
Translation (Danio rerio)
Eukaryotic Translation Initiation (Danio rerio)
Cap-dependent Translation Initiation (Danio rerio)
Recycling of eIF2:GDP (Danio rerio)
eIF2 activation (Danio rerio)
GDP [cytosol]
Organelle biogenesis and maintenance (Danio rerio)
Cilium Assembly (Danio rerio)
Cargo trafficking to the periciliary membrane (Danio rerio)
VxPx cargo-targeting to cilium (Danio rerio)
RAB3IP stimulates nucleotide exchange on RAB8A (Danio rerio)
GDP [cytosol]
Signal Transduction (Danio rerio)
Death Receptor Signaling (Danio rerio)
p75 NTR receptor-mediated signalling (Danio rerio)
Cell death signalling via NRAGE, NRIF and NADE (Danio rerio)
NRAGE signals death through JNK (Danio rerio)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Danio rerio)
GDP [cytosol]
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
Intrinsic nucleotide exchange on RAS (Danio rerio)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
RAS processing (Danio rerio)
mature p21 RAS binds GDP (Danio rerio)
GDP [cytosol]
MTOR signalling (Danio rerio)
GTP loading by Rheb (Danio rerio)
GDP [cytosol]
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (12/13) signalling events (Danio rerio)
GEFs activate RhoA,B,C (Danio rerio)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Danio rerio)
GDP [cytosol]
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
GDP [cytosol]
Opioid Signalling (Danio rerio)
G-protein activation (Danio rerio)
G-protein alpha subunit is inactivated (Danio rerio)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Danio rerio)
GDP [cytosol]
G alpha (q) signalling events (Danio rerio)
Gastrin-CREB signalling pathway via PKC and MAPK (Danio rerio)
EGFR Transactivation by Gastrin (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
Signaling by PTK6 (Danio rerio)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Danio rerio)
Activation of RAC1 by the PXN:CRK complex (Danio rerio)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by EGFR (Danio rerio)
GRB2 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
GDP [cytosol]
SHC1 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
GDP [cytosol]
Signaling by ERBB2 (Danio rerio)
GRB2 events in ERBB2 signaling (Danio rerio)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
GDP [cytosol]
Signaling by ERBB4 (Danio rerio)
SHC1 events in ERBB4 signaling (Danio rerio)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)
GDP [cytosol]
Signaling by FGFR (Danio rerio)
Signaling by FGFR1 (Danio rerio)
Downstream signaling of activated FGFR1 (Danio rerio)
FRS-mediated FGFR1 signaling (Danio rerio)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Danio rerio)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Signaling by FGFR2 (Danio rerio)
Downstream signaling of activated FGFR2 (Danio rerio)
FRS-mediated FGFR2 signaling (Danio rerio)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Danio rerio)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Signaling by FGFR3 (Danio rerio)
Downstream signaling of activated FGFR3 (Danio rerio)
FRS-mediated FGFR3 signaling (Danio rerio)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Danio rerio)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Signaling by FGFR4 (Danio rerio)
Downstream signaling of activated FGFR4 (Danio rerio)
FRS-mediated FGFR4 signaling (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
GDP [cytosol]
Signaling by MET (Danio rerio)
MET activates RAS signaling (Danio rerio)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Danio rerio)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Danio rerio)
GDP [cytosol]
Signaling by NTRKs (Danio rerio)
Signaling by NTRK1 (TRKA) (Danio rerio)
Signalling to ERKs (Danio rerio)
Prolonged ERK activation events (Danio rerio)
ARMS-mediated activation (Danio rerio)
C3G stimulates nucleotide exchange on Rap1 (Danio rerio)
GDP [cytosol]
Signaling by PDGF (Danio rerio)
Downstream signal transduction (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
GDP [cytosol]
Signaling by SCF-KIT (Danio rerio)
Activation of RAS by p-KIT bound SOS1 (Danio rerio)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase cycle (Danio rerio)
CDC42 GTPase cycle (Danio rerio)
CDC42 GEFs activate CDC42 (Danio rerio)
GDP [cytosol]
RAC1 GTPase cycle (Danio rerio)
RAC1 GEFs activate RAC1 (Danio rerio)
GDP [cytosol]
RAC2 GTPase cycle (Danio rerio)
RAC2 GEFs activate RAC2 (Danio rerio)
GDP [cytosol]
RAC3 GTPase cycle (Danio rerio)
RAC3 GEFs activate RAC3 (Danio rerio)
GDP [cytosol]
RHOA GTPase cycle (Danio rerio)
RHOA GEFs activate RHOA (Danio rerio)
GDP [cytosol]
RHOD GTPase cycle (Danio rerio)
RHOD auto-activates (Danio rerio)
GDP [cytosol]
RHOF GTPase cycle (Danio rerio)
RHOF auto-activates (Danio rerio)
GDP [cytosol]
RHOG GTPase cycle (Danio rerio)
RHOG GEFs activate RHOG (Danio rerio)
GDP [cytosol]
RHOU GTPase cycle (Danio rerio)
RHOU auto-activates (Danio rerio)
GDP [cytosol]
RHOV GTPase cycle (Danio rerio)
RHOV binds GTP (Danio rerio)
GDP [cytosol]
Transport of small molecules (Danio rerio)
Aquaporin-mediated transport (Danio rerio)
Vasopressin regulates renal water homeostasis via Aquaporins (Danio rerio)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Danio rerio)
GDP [cytosol]
Vesicle-mediated transport (Danio rerio)
Membrane Trafficking (Danio rerio)
ER to Golgi Anterograde Transport (Danio rerio)
COPII-mediated vesicle transport (Danio rerio)
Nucleotide exchange on RAB1 (Danio rerio)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Danio rerio)
GDP [cytosol]
Rab regulation of trafficking (Danio rerio)
RAB GEFs exchange GTP for GDP on RABs (Danio rerio)
DENND6A,B exchange GTP for GDP on RAB14 (Danio rerio)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Danio rerio)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Danio rerio)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Danio rerio)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Danio rerio)
Lysosome Vesicle Biogenesis (Danio rerio)
trans-Golgi Network Lysosomal Vesicle Scission (Danio rerio)
GDP [cytosol]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
M Phase (Dictyostelium discoideum)
Mitotic Metaphase and Anaphase (Dictyostelium discoideum)
Mitotic Anaphase (Dictyostelium discoideum)
Nuclear Envelope (NE) Reassembly (Dictyostelium discoideum)
Postmitotic nuclear pore complex (NPC) reformation (Dictyostelium discoideum)
RCC1 stimulates GDP to GTP exchange on RAN (Dictyostelium discoideum)
GDP [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to starvation (Dictyostelium discoideum)
Amino acids regulate mTORC1 (Dictyostelium discoideum)
RRAGA,B exchanges GDP for GTP (Dictyostelium discoideum)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Dictyostelium discoideum)
GDP [cytosol]
Hemostasis (Dictyostelium discoideum)
Platelet activation, signaling and aggregation (Dictyostelium discoideum)
Platelet Aggregation (Plug Formation) (Dictyostelium discoideum)
Integrin signaling (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
GDP [cytosol]
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Rap1 signalling (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
GDP [cytosol]
Metabolism (Dictyostelium discoideum)
Integration of energy metabolism (Dictyostelium discoideum)
Regulation of insulin secretion (Dictyostelium discoideum)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Dictyostelium discoideum)
RAP1A exchanges GDP for GTP (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
PCK1 phosphorylates OA to yield PEP (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)
GDP [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
Addition of a second mannose to the N-glycan precursor by ALG2 (Dictyostelium discoideum)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Dictyostelium discoideum)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Dictyostelium discoideum)
ER to Golgi Anterograde Transport (Dictyostelium discoideum)
COPII-mediated vesicle transport (Dictyostelium discoideum)
Nucleotide exchange on RAB1 (Dictyostelium discoideum)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Dictyostelium discoideum)
GDP [cytosol]
Translation (Dictyostelium discoideum)
Eukaryotic Translation Initiation (Dictyostelium discoideum)
Cap-dependent Translation Initiation (Dictyostelium discoideum)
Recycling of eIF2:GDP (Dictyostelium discoideum)
eIF2 activation (Dictyostelium discoideum)
GDP [cytosol]
Organelle biogenesis and maintenance (Dictyostelium discoideum)
Cilium Assembly (Dictyostelium discoideum)
Cargo trafficking to the periciliary membrane (Dictyostelium discoideum)
VxPx cargo-targeting to cilium (Dictyostelium discoideum)
GBF1 stimulates nucleotide exchange on ARF4 (Dictyostelium discoideum)
GDP [cytosol]
Signal Transduction (Dictyostelium discoideum)
Death Receptor Signaling (Dictyostelium discoideum)
p75 NTR receptor-mediated signalling (Dictyostelium discoideum)
Cell death signalling via NRAGE, NRIF and NADE (Dictyostelium discoideum)
NRAGE signals death through JNK (Dictyostelium discoideum)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Dictyostelium discoideum)
GDP [cytosol]
Integrin signaling (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
GDP [cytosol]
MTOR signalling (Dictyostelium discoideum)
GTP loading by Rheb (Dictyostelium discoideum)
GDP [cytosol]
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (i) signalling events (Dictyostelium discoideum)
Liganded Gi-activating GPCR acts as a GEF for Gi (Dictyostelium discoideum)
GDP [cytosol]
Opioid Signalling (Dictyostelium discoideum)
G-protein activation (Dictyostelium discoideum)
G-protein alpha subunit is inactivated (Dictyostelium discoideum)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by PTK6 (Dictyostelium discoideum)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Dictyostelium discoideum)
Activation of RAC1 by the PXN:CRK complex (Dictyostelium discoideum)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
Signaling by Rho GTPases (Dictyostelium discoideum)
RHO GTPase cycle (Dictyostelium discoideum)
CDC42 GTPase cycle (Dictyostelium discoideum)
CDC42 GEFs activate CDC42 (Dictyostelium discoideum)
GDP [cytosol]
RAC1 GTPase cycle (Dictyostelium discoideum)
RAC1 GEFs activate RAC1 (Dictyostelium discoideum)
GDP [cytosol]
RAC2 GTPase cycle (Dictyostelium discoideum)
RAC2 GEFs activate RAC2 (Dictyostelium discoideum)
GDP [cytosol]
RAC3 GTPase cycle (Dictyostelium discoideum)
RAC3 GEFs activate RAC3 (Dictyostelium discoideum)
GDP [cytosol]
RHOG GTPase cycle (Dictyostelium discoideum)
RHOG GEFs activate RHOG (Dictyostelium discoideum)
GDP [cytosol]
RHOJ GTPase cycle (Dictyostelium discoideum)
RHOJ GEFs activate RHOJ (Dictyostelium discoideum)
GDP [cytosol]
RHOQ GTPase cycle (Dictyostelium discoideum)
RHOQ GEFs activate RHOQ (Dictyostelium discoideum)
GDP [cytosol]
RHOU GTPase cycle (Dictyostelium discoideum)
RHOU auto-activates (Dictyostelium discoideum)
GDP [cytosol]
RHOV GTPase cycle (Dictyostelium discoideum)
RHOV binds GTP (Dictyostelium discoideum)
GDP [cytosol]
Vesicle-mediated transport (Dictyostelium discoideum)
Membrane Trafficking (Dictyostelium discoideum)
ER to Golgi Anterograde Transport (Dictyostelium discoideum)
COPII-mediated vesicle transport (Dictyostelium discoideum)
Nucleotide exchange on RAB1 (Dictyostelium discoideum)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Dictyostelium discoideum)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Dictyostelium discoideum)
Golgi-to-ER retrograde transport (Dictyostelium discoideum)
COPI-dependent Golgi-to-ER retrograde traffic (Dictyostelium discoideum)
GBF1 stimulates nucleotide exchange on ARF (Dictyostelium discoideum)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Dictyostelium discoideum)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Dictyostelium discoideum)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Dictyostelium discoideum)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Dictyostelium discoideum)
GDP [cytosol]
Rab regulation of trafficking (Dictyostelium discoideum)
RAB GEFs exchange GTP for GDP on RABs (Dictyostelium discoideum)
DENND1s exchange GTP for GDP on RAB35 (Dictyostelium discoideum)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Dictyostelium discoideum)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Dictyostelium discoideum)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Dictyostelium discoideum)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Dictyostelium discoideum)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Dictyostelium discoideum)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Dictyostelium discoideum)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Dictyostelium discoideum)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Dictyostelium discoideum)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Dictyostelium discoideum)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Dictyostelium discoideum)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Dictyostelium discoideum)
trans-Golgi Network Coat Activation (Dictyostelium discoideum)
GDP [cytosol]
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Nuclear Envelope (NE) Reassembly (Drosophila melanogaster)
Postmitotic nuclear pore complex (NPC) reformation (Drosophila melanogaster)
RCC1 stimulates GDP to GTP exchange on RAN (Drosophila melanogaster)
GDP [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to starvation (Drosophila melanogaster)
Amino acids regulate mTORC1 (Drosophila melanogaster)
RRAGA,B exchanges GDP for GTP (Drosophila melanogaster)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Drosophila melanogaster)
GDP [cytosol]
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPH-ephrin mediated repulsion of cells (Drosophila melanogaster)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
EPHA-mediated growth cone collapse (Drosophila melanogaster)
NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)
GDP [cytosol]
EPHB-mediated forward signaling (Drosophila melanogaster)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Drosophila melanogaster)
GDP [cytosol]
L1CAM interactions (Drosophila melanogaster)
Recycling pathway of L1 (Drosophila melanogaster)
Formation of clathrin coated vesicle (Drosophila melanogaster)
GDP [cytosol]
Signal transduction by L1 (Drosophila melanogaster)
Activation of Rac1 by VAV2 (Drosophila melanogaster)
GDP [cytosol]
NCAM signaling for neurite out-growth (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
GDP [cytosol]
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Activation of Cdc42 (Drosophila melanogaster)
GDP [cytosol]
Activation of Rac1 (Drosophila melanogaster)
GDP [cytosol]
Semaphorin interactions (Drosophila melanogaster)
Sema4D in semaphorin signaling (Drosophila melanogaster)
Sema4D induced cell migration and growth-cone collapse (Drosophila melanogaster)
Activation of Rho by LARG and PDZ-RhoGEF (Drosophila melanogaster)
GDP [cytosol]
Drosophila signaling pathways (Drosophila melanogaster)
Insulin receptor mediated signaling (Drosophila melanogaster)
TOR signaling pathway (Drosophila melanogaster)
GDP is exchanged for GTP on DRheb (Drosophila melanogaster)
GDP [cytosol]
Planar Cell Polarity pathway (Drosophila melanogaster)
Activation of Downstream Effectors (Drosophila melanogaster)
RHO1 signalling (Drosophila melanogaster)
RHO1 GTPase cycle (Drosophila melanogaster)
RHOGEF2 stimulates nucleotide exchange of RHO1:GDP complex (Drosophila melanogaster)
GDP [cytosol]
Drug ADME (Drosophila melanogaster)
Azathioprine ADME (Drosophila melanogaster)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Drosophila melanogaster)
GDP [cytosol]
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
GDP [cytosol]
Signal amplification (Drosophila melanogaster)
ADP signalling through P2Y purinoceptor 12 (Drosophila melanogaster)
Gi activation by P2Y purinoceptor 12 (Drosophila melanogaster)
GDP [cytosol]
Thromboxane signalling through TP receptor (Drosophila melanogaster)
G13 activation by TP receptor (Drosophila melanogaster)
GDP [cytosol]
Gq activation by TP receptor (Drosophila melanogaster)
GDP [cytosol]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Rap1 signalling (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
GDP [cytosol]
Cytokine Signaling in Immune system (Drosophila melanogaster)
FLT3 Signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
GDP [cytosol]
Innate Immune System (Drosophila melanogaster)
DAP12 interactions (Drosophila melanogaster)
DAP12 signaling (Drosophila melanogaster)
Activation of RAC1 by VAV2/3 (Drosophila melanogaster)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
Activation of RAC1 by VAV (Drosophila melanogaster)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
GDP [cytosol]
Metabolism (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Adrenaline,noradrenaline inhibits insulin secretion (Drosophila melanogaster)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Drosophila melanogaster)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Drosophila melanogaster)
RAP1A exchanges GDP for GTP (Drosophila melanogaster)
GDP [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PCK1 phosphorylates OA to yield PEP (Drosophila melanogaster)
GDP [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Drosophila melanogaster)
GDP [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
Addition of a second mannose to the N-glycan precursor by ALG2 (Drosophila melanogaster)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Drosophila melanogaster)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Drosophila melanogaster)
ER to Golgi Anterograde Transport (Drosophila melanogaster)
COPII-mediated vesicle transport (Drosophila melanogaster)
Nucleotide exchange on RAB1 (Drosophila melanogaster)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Drosophila melanogaster)
GDP [cytosol]
Translation (Drosophila melanogaster)
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
Recycling of eIF2:GDP (Drosophila melanogaster)
eIF2 activation (Drosophila melanogaster)
GDP [cytosol]
Organelle biogenesis and maintenance (Drosophila melanogaster)
Cilium Assembly (Drosophila melanogaster)
Cargo trafficking to the periciliary membrane (Drosophila melanogaster)
VxPx cargo-targeting to cilium (Drosophila melanogaster)
GBF1 stimulates nucleotide exchange on ARF4 (Drosophila melanogaster)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Drosophila melanogaster)
GDP [cytosol]
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
p75 NTR receptor-mediated signalling (Drosophila melanogaster)
Cell death signalling via NRAGE, NRIF and NADE (Drosophila melanogaster)
NRAGE signals death through JNK (Drosophila melanogaster)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Drosophila melanogaster)
GDP [cytosol]
Integrin signaling (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
GDP [cytosol]
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
RAS processing (Drosophila melanogaster)
mature p21 RAS binds GDP (Drosophila melanogaster)
GDP [cytosol]
MTOR signalling (Drosophila melanogaster)
GTP loading by Rheb (Drosophila melanogaster)
GDP [cytosol]
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
GEFs activate RhoA,B,C (Drosophila melanogaster)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Drosophila melanogaster)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Drosophila melanogaster)
GDP [cytosol]
G alpha (i) signalling events (Drosophila melanogaster)
Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
GDP [cytosol]
Opioid Signalling (Drosophila melanogaster)
G-protein activation (Drosophila melanogaster)
G-protein alpha subunit is inactivated (Drosophila melanogaster)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Drosophila melanogaster)
GDP [cytosol]
G alpha (q) signalling events (Drosophila melanogaster)
Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
EGFR Transactivation by Gastrin (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
GDP [cytosol]
G alpha (s) signalling events (Drosophila melanogaster)
Liganded Gs-activating GPCR acts as a GEF for Gs (Drosophila melanogaster)
GDP [cytosol]
G alpha (z) signalling events (Drosophila melanogaster)
Liganded Gz-activating GPCR acts as a GEF for Gz (Drosophila melanogaster)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
Activation of RAC1 by the PXN:CRK complex (Drosophila melanogaster)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
GRB2 events in EGFR signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)
GDP [cytosol]
SHC1 events in EGFR signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Drosophila melanogaster)
GDP [cytosol]
Signaling by ERBB2 (Drosophila melanogaster)
GRB2 events in ERBB2 signaling (Drosophila melanogaster)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
GDP [cytosol]
Signaling by ERBB4 (Drosophila melanogaster)
SHC1 events in ERBB4 signaling (Drosophila melanogaster)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)
GDP [cytosol]
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Downstream signaling of activated FGFR1 (Drosophila melanogaster)
FRS-mediated FGFR1 signaling (Drosophila melanogaster)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Drosophila melanogaster)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
FRS-mediated FGFR2 signaling (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
FRS-mediated FGFR3 signaling (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Drosophila melanogaster)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
FRS-mediated FGFR4 signaling (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
GDP [cytosol]
Signaling by SCF-KIT (Drosophila melanogaster)
Activation of RAC1 (Drosophila melanogaster)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)
GDP [cytosol]
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Drosophila melanogaster)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
CDC42 GTPase cycle (Drosophila melanogaster)
CDC42 GEFs activate CDC42 (Drosophila melanogaster)
GDP [cytosol]
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 GEFs activate RAC1 (Drosophila melanogaster)
GDP [cytosol]
RAC2 GTPase cycle (Drosophila melanogaster)
RAC2 GEFs activate RAC2 (Drosophila melanogaster)
GDP [cytosol]
RAC3 GTPase cycle (Drosophila melanogaster)
RAC3 GEFs activate RAC3 (Drosophila melanogaster)
GDP [cytosol]
RHOA GTPase cycle (Drosophila melanogaster)
RHOA GEFs activate RHOA (Drosophila melanogaster)
GDP [cytosol]
RHOB GTPase cycle (Drosophila melanogaster)
RHOB GEFs activate RHOB (Drosophila melanogaster)
GDP [cytosol]
RHOD GTPase cycle (Drosophila melanogaster)
RHOD auto-activates (Drosophila melanogaster)
GDP [cytosol]
RHOF GTPase cycle (Drosophila melanogaster)
RHOF auto-activates (Drosophila melanogaster)
GDP [cytosol]
RHOG GTPase cycle (Drosophila melanogaster)
RHOG GEFs activate RHOG (Drosophila melanogaster)
GDP [cytosol]
RHOJ GTPase cycle (Drosophila melanogaster)
RHOJ GEFs activate RHOJ (Drosophila melanogaster)
GDP [cytosol]
RHOQ GTPase cycle (Drosophila melanogaster)
RHOQ GEFs activate RHOQ (Drosophila melanogaster)
GDP [cytosol]
RHOU GTPase cycle (Drosophila melanogaster)
RHOU auto-activates (Drosophila melanogaster)
GDP [cytosol]
RHOV GTPase cycle (Drosophila melanogaster)
RHOV binds GTP (Drosophila melanogaster)
GDP [cytosol]
Signaling by WNT (Drosophila melanogaster)
Beta-catenin independent WNT signaling (Drosophila melanogaster)
Ca2+ pathway (Drosophila melanogaster)
WNT:FZD complex promotes G-protein nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
ER to Golgi Anterograde Transport (Drosophila melanogaster)
COPII-mediated vesicle transport (Drosophila melanogaster)
Nucleotide exchange on RAB1 (Drosophila melanogaster)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Drosophila melanogaster)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Drosophila melanogaster)
Golgi-to-ER retrograde transport (Drosophila melanogaster)
COPI-dependent Golgi-to-ER retrograde traffic (Drosophila melanogaster)
GBF1 stimulates nucleotide exchange on ARF (Drosophila melanogaster)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Drosophila melanogaster)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Drosophila melanogaster)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Drosophila melanogaster)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Drosophila melanogaster)
GDP [cytosol]
Rab regulation of trafficking (Drosophila melanogaster)
RAB GEFs exchange GTP for GDP on RABs (Drosophila melanogaster)
DENND1s exchange GTP for GDP on RAB35 (Drosophila melanogaster)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Drosophila melanogaster)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Drosophila melanogaster)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Drosophila melanogaster)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Drosophila melanogaster)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Drosophila melanogaster)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Drosophila melanogaster)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Drosophila melanogaster)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Drosophila melanogaster)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Drosophila melanogaster)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Drosophila melanogaster)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Drosophila melanogaster)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Drosophila melanogaster)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Drosophila melanogaster)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Drosophila melanogaster)
Golgi Associated Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
GDP [cytosol]
trans-Golgi Network Coat Activation (Drosophila melanogaster)
GDP [cytosol]
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Metaphase and Anaphase (Gallus gallus)
Mitotic Anaphase (Gallus gallus)
Nuclear Envelope (NE) Reassembly (Gallus gallus)
Postmitotic nuclear pore complex (NPC) reformation (Gallus gallus)
RCC1 stimulates GDP to GTP exchange on RAN (Gallus gallus)
GDP [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to starvation (Gallus gallus)
Amino acids regulate mTORC1 (Gallus gallus)
RRAGA,B exchanges GDP for GTP (Gallus gallus)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Gallus gallus)
GDP [cytosol]
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPH-ephrin mediated repulsion of cells (Gallus gallus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
GDP [cytosol]
EPHA-mediated growth cone collapse (Gallus gallus)
NGEF exchanges GTP for GDP on RHOA (Gallus gallus)
GDP [cytosol]
EPHB-mediated forward signaling (Gallus gallus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Gallus gallus)
GDP [cytosol]
L1CAM interactions (Gallus gallus)
Recycling pathway of L1 (Gallus gallus)
Formation of clathrin coated vesicle (Gallus gallus)
GDP [cytosol]
Signal transduction by L1 (Gallus gallus)
Activation of Rac1 by VAV2 (Gallus gallus)
GDP [cytosol]
NCAM signaling for neurite out-growth (Gallus gallus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Gallus gallus)
GDP [cytosol]
Semaphorin interactions (Gallus gallus)
Sema4D in semaphorin signaling (Gallus gallus)
Sema4D induced cell migration and growth-cone collapse (Gallus gallus)
Activation of Rho by LARG and PDZ-RhoGEF (Gallus gallus)
GDP [cytosol]
Drug ADME (Gallus gallus)
Azathioprine ADME (Gallus gallus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Gallus gallus)
GDP [cytosol]
Hemostasis (Gallus gallus)
Cell surface interactions at the vascular wall (Gallus gallus)
Tie2 Signaling (Gallus gallus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Gallus gallus)
GDP [cytosol]
Platelet activation, signaling and aggregation (Gallus gallus)
GPVI-mediated activation cascade (Gallus gallus)
VAV2 is a GEF for Rho/Rac family kinases (Gallus gallus)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Gallus gallus)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Gallus gallus)
Integrin signaling (Gallus gallus)
Activation of Rap1 by cytosolic GEFs (Gallus gallus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Gallus gallus)
GDP [cytosol]
Signal amplification (Gallus gallus)
ADP signalling through P2Y purinoceptor 12 (Gallus gallus)
Gi activation by P2Y purinoceptor 12 (Gallus gallus)
GDP [cytosol]
Thromboxane signalling through TP receptor (Gallus gallus)
G13 activation by TP receptor (Gallus gallus)
GDP [cytosol]
Gq activation by TP receptor (Gallus gallus)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Gallus gallus)
Thrombin-activated PARs activate G12/13 (Gallus gallus)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Gallus gallus)
GDP [cytosol]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Gallus gallus)
Disassembly of COPII coated vesicle (Gallus gallus)
GDP [cytosol]
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
CD28 dependent Vav1 pathway (Gallus gallus)
Activation of Cdc42 by pVav1 (Gallus gallus)
GDP [cytosol]
Activation of Rac1 by pVav1 (Gallus gallus)
GDP [cytosol]
MHC class II antigen presentation (Gallus gallus)
Internalization of MHC II:Ii clathrin coated vesicle (Gallus gallus)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Gallus gallus)
GDP [cytosol]
Rap1 signalling (Gallus gallus)
Activation of Rap1 by cytosolic GEFs (Gallus gallus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Gallus gallus)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Downstream signaling events of B Cell Receptor (BCR) (Gallus gallus)
Activation of RAS in B cells (Gallus gallus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Gallus gallus)
GDP [cytosol]
Cytokine Signaling in Immune system (Gallus gallus)
FLT3 Signaling (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Gallus gallus)
GDP [cytosol]
Innate Immune System (Gallus gallus)
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
Activation of RAC1 by VAV2/3 (Gallus gallus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Gallus gallus)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Activation of RAC1 by VAV (Gallus gallus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Gallus gallus)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Gallus gallus)
GDP [cytosol]
Activation of RAC1 by VAV (Gallus gallus)
GDP [cytosol]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] (Gallus gallus)
GDP [cytosol]
Nucleotide metabolism (Gallus gallus)
Purine metabolism (Gallus gallus)
De novo synthesis of AMP (Gallus gallus)
inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate (Gallus gallus)
GDP [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Gallus gallus)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Gallus gallus)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Gallus gallus)
ER to Golgi Anterograde Transport (Gallus gallus)
COPII-mediated vesicle transport (Gallus gallus)
Nucleotide exchange on RAB1 (Gallus gallus)
GDP [cytosol]
Translation (Gallus gallus)
Eukaryotic Translation Initiation (Gallus gallus)
Cap-dependent Translation Initiation (Gallus gallus)
Recycling of eIF2:GDP (Gallus gallus)
eIF2 activation (Gallus gallus)
GDP [cytosol]
Organelle biogenesis and maintenance (Gallus gallus)
Cilium Assembly (Gallus gallus)
Anchoring of the basal body to the plasma membrane (Gallus gallus)
RAB3IP stimulates nucleotide exchange on RAB8A (Gallus gallus)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Gallus gallus)
VxPx cargo-targeting to cilium (Gallus gallus)
GBF1 stimulates nucleotide exchange on ARF4 (Gallus gallus)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Gallus gallus)
GDP [cytosol]
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
p75 NTR receptor-mediated signalling (Gallus gallus)
Cell death signalling via NRAGE, NRIF and NADE (Gallus gallus)
NRAGE signals death through JNK (Gallus gallus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Gallus gallus)
GDP [cytosol]
Integrin signaling (Gallus gallus)
Activation of Rap1 by cytosolic GEFs (Gallus gallus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Gallus gallus)
GDP [cytosol]
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
Intrinsic nucleotide exchange on RAS (Gallus gallus)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
RAS processing (Gallus gallus)
mature p21 RAS binds GDP (Gallus gallus)
GDP [cytosol]
MTOR signalling (Gallus gallus)
GTP loading by Rheb (Gallus gallus)
GDP [cytosol]
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (12/13) signalling events (Gallus gallus)
GEFs activate RhoA,B,C (Gallus gallus)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Gallus gallus)
GDP [cytosol]
G alpha (i) signalling events (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
GDP [cytosol]
Opioid Signalling (Gallus gallus)
G-protein activation (Gallus gallus)
G-protein alpha subunit is inactivated (Gallus gallus)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Gallus gallus)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Gallus gallus)
GDP [cytosol]
G alpha (q) signalling events (Gallus gallus)
Gastrin-CREB signalling pathway via PKC and MAPK (Gallus gallus)
EGFR Transactivation by Gastrin (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Gallus gallus)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
GDP [cytosol]
G alpha (s) signalling events (Gallus gallus)
GPER1 signaling (Gallus gallus)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Gallus gallus)
GDP [cytosol]
Liganded Gs-activating GPCR acts as a GEF for Gs (Gallus gallus)
GDP [cytosol]
G alpha (z) signalling events (Gallus gallus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Gallus gallus)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Gallus gallus)
Signaling by PTK6 (Gallus gallus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Gallus gallus)
Activation of RAC1 by the PXN:CRK complex (Gallus gallus)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by EGFR (Gallus gallus)
GRB2 events in EGFR signaling (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Gallus gallus)
GDP [cytosol]
SHC1 events in EGFR signaling (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Gallus gallus)
GDP [cytosol]
Signaling by ERBB2 (Gallus gallus)
GRB2 events in ERBB2 signaling (Gallus gallus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)
GDP [cytosol]
Signaling by ERBB4 (Gallus gallus)
SHC1 events in ERBB4 signaling (Gallus gallus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Gallus gallus)
GDP [cytosol]
Signaling by FGFR (Gallus gallus)
Signaling by FGFR1 (Gallus gallus)
Downstream signaling of activated FGFR1 (Gallus gallus)
FRS-mediated FGFR1 signaling (Gallus gallus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Gallus gallus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Signaling by FGFR2 (Gallus gallus)
Downstream signaling of activated FGFR2 (Gallus gallus)
FRS-mediated FGFR2 signaling (Gallus gallus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Gallus gallus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Signaling by FGFR3 (Gallus gallus)
Downstream signaling of activated FGFR3 (Gallus gallus)
FRS-mediated FGFR3 signaling (Gallus gallus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Gallus gallus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Signaling by FGFR4 (Gallus gallus)
Downstream signaling of activated FGFR4 (Gallus gallus)
FRS-mediated FGFR4 signaling (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Gallus gallus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
GDP [cytosol]
Signaling by MET (Gallus gallus)
MET activates RAS signaling (Gallus gallus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Gallus gallus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Gallus gallus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Gallus gallus)
GDP [cytosol]
MET promotes cell motility (Gallus gallus)
MET activates RAP1 and RAC1 (Gallus gallus)
DOCK7 activates RAC1 (Gallus gallus)
GDP [cytosol]
RAPGEF1 activates RAP1 (Gallus gallus)
GDP [cytosol]
Signaling by NTRKs (Gallus gallus)
Signaling by NTRK1 (TRKA) (Gallus gallus)
Signalling to ERKs (Gallus gallus)
Prolonged ERK activation events (Gallus gallus)
ARMS-mediated activation (Gallus gallus)
C3G stimulates nucleotide exchange on Rap1 (Gallus gallus)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Gallus gallus)
Activated NTRK2 signals through FYN (Gallus gallus)
NTRK2 activates RAC1 (Gallus gallus)
DOCK3 activates RAC1 (Gallus gallus)
GDP [cytosol]
Signaling by PDGF (Gallus gallus)
Downstream signal transduction (Gallus gallus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Gallus gallus)
GDP [cytosol]
Signaling by SCF-KIT (Gallus gallus)
Activation of RAS by p-KIT bound SOS1 (Gallus gallus)
GDP [cytosol]
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
CDC42 GTPase cycle (Gallus gallus)
CDC42 GEFs activate CDC42 (Gallus gallus)
GDP [cytosol]
RAC1 GTPase cycle (Gallus gallus)
RAC1 GEFs activate RAC1 (Gallus gallus)
GDP [cytosol]
RAC2 GTPase cycle (Gallus gallus)
RAC2 GEFs activate RAC2 (Gallus gallus)
GDP [cytosol]
RAC3 GTPase cycle (Gallus gallus)
RAC3 GEFs activate RAC3 (Gallus gallus)
GDP [cytosol]
RHOA GTPase cycle (Gallus gallus)
RHOA GEFs activate RHOA (Gallus gallus)
GDP [cytosol]
RHOB GTPase cycle (Gallus gallus)
RHOB GEFs activate RHOB (Gallus gallus)
GDP [cytosol]
RHOC GTPase cycle (Gallus gallus)
RHOC GEFs activate RHOC (Gallus gallus)
GDP [cytosol]
RHOD GTPase cycle (Gallus gallus)
RHOD auto-activates (Gallus gallus)
GDP [cytosol]
RHOF GTPase cycle (Gallus gallus)
RHOF auto-activates (Gallus gallus)
GDP [cytosol]
RHOG GTPase cycle (Gallus gallus)
RHOG GEFs activate RHOG (Gallus gallus)
GDP [cytosol]
RHOJ GTPase cycle (Gallus gallus)
RHOJ GEFs activate RHOJ (Gallus gallus)
GDP [cytosol]
RHOQ GTPase cycle (Gallus gallus)
RHOQ GEFs activate RHOQ (Gallus gallus)
GDP [cytosol]
RHOU GTPase cycle (Gallus gallus)
RHOU auto-activates (Gallus gallus)
GDP [cytosol]
RHOV GTPase cycle (Gallus gallus)
RHOV binds GTP (Gallus gallus)
GDP [cytosol]
Signaling by WNT (Gallus gallus)
Beta-catenin independent WNT signaling (Gallus gallus)
Ca2+ pathway (Gallus gallus)
WNT:FZD complex promotes G-protein nucleotide exchange (Gallus gallus)
GDP [cytosol]
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
ER to Golgi Anterograde Transport (Gallus gallus)
COPII-mediated vesicle transport (Gallus gallus)
Nucleotide exchange on RAB1 (Gallus gallus)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Gallus gallus)
Golgi-to-ER retrograde transport (Gallus gallus)
COPI-independent Golgi-to-ER retrograde traffic (Gallus gallus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Gallus gallus)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Gallus gallus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Gallus gallus)
GDP [cytosol]
Rab regulation of trafficking (Gallus gallus)
RAB GEFs exchange GTP for GDP on RABs (Gallus gallus)
DENND1s exchange GTP for GDP on RAB35 (Gallus gallus)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Gallus gallus)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Gallus gallus)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Gallus gallus)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Gallus gallus)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Gallus gallus)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Gallus gallus)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Gallus gallus)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Gallus gallus)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Gallus gallus)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Gallus gallus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Gallus gallus)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Gallus gallus)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Gallus gallus)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Gallus gallus)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Gallus gallus)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Gallus gallus)
Golgi Associated Vesicle Biogenesis (Gallus gallus)
trans-Golgi Network Vesicle Scission (Gallus gallus)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Gallus gallus)
trans-Golgi Network Lysosomal Vesicle Scission (Gallus gallus)
GDP [cytosol]
trans-Golgi Network Coat Activation (Gallus gallus)
GDP [cytosol]
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Postmitotic nuclear pore complex (NPC) reformation (Homo sapiens)
RCC1 stimulates GDP to GTP exchange on RAN (Homo sapiens)
GDP [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
RRAGA,B exchanges GDP for GTP (Homo sapiens)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Homo sapiens)
GDP [cytosol]
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
GDP [cytosol]
EPHA-mediated growth cone collapse (Homo sapiens)
NGEF exchanges GTP for GDP on RHOA (Homo sapiens)
GDP [cytosol]
EPHB-mediated forward signaling (Homo sapiens)
ITSN1 exchanges GTP for GDP on CDC42, activating it (Homo sapiens)
GDP [cytosol]
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Homo sapiens)
GDP [cytosol]
L1CAM interactions (Homo sapiens)
Recycling pathway of L1 (Homo sapiens)
Formation of clathrin coated vesicle (Homo sapiens)
GDP [cytosol]
Signal transduction by L1 (Homo sapiens)
Activation of Rac1 by VAV2 (Homo sapiens)
GDP [cytosol]
NCAM signaling for neurite out-growth (Homo sapiens)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Homo sapiens)
GDP [cytosol]
Netrin-1 signaling (Homo sapiens)
DCC mediated attractive signaling (Homo sapiens)
Activation of Cdc42 (Homo sapiens)
GDP [cytosol]
Activation of Rac1 (Homo sapiens)
GDP [cytosol]
Semaphorin interactions (Homo sapiens)
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (Homo sapiens)
Activation of Rac1 by FARP2 (Homo sapiens)
GDP [cytosol]
Sema4D in semaphorin signaling (Homo sapiens)
Sema4D induced cell migration and growth-cone collapse (Homo sapiens)
Activation of Rho by LARG and PDZ-RhoGEF (Homo sapiens)
GDP [cytosol]
Signaling by ROBO receptors (Homo sapiens)
Activation of RAC1 (Homo sapiens)
Activation of RAC1 by SOS (Homo sapiens)
GDP [cytosol]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Signaling by FLT3 ITD and TKD mutants (Homo sapiens)
FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS (Homo sapiens)
GDP [cytosol]
Signaling by FLT3 fusion proteins (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants (Homo sapiens)
GDP [cytosol]
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by EGFRvIII in Cancer (Homo sapiens)
Constitutive Signaling by EGFRvIII (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII) (Homo sapiens)
GDP [cytosol]
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII) (Homo sapiens)
GDP [cytosol]
Signaling by Ligand-Responsive EGFR Variants in Cancer (Homo sapiens)
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)
GDP [cytosol]
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)
GDP [cytosol]
Signaling by ERBB2 in Cancer (Homo sapiens)
Constitutive Signaling by Overexpressed ERBB2 (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1 (Homo sapiens)
GDP [cytosol]
Signaling by ERBB2 ECD mutants (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 (Homo sapiens)
GDP [cytosol]
RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 (Homo sapiens)
GDP [cytosol]
Signaling by ERBB2 KD Mutants (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants (Homo sapiens)
GDP [cytosol]
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR (Homo sapiens)
GDP [cytosol]
Signaling by ERBB2 TMD/JMD mutants (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants (Homo sapiens)
GDP [cytosol]
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR (Homo sapiens)
GDP [cytosol]
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by FGFR2 in disease (Homo sapiens)
Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by FGFR3 in disease (Homo sapiens)
Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by FGFR4 in disease (Homo sapiens)
Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by KIT in disease (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)
GDP [cytosol]
Signaling by PDGFR in disease (Homo sapiens)
Signaling by PDGFRA extracellular domain mutants (Homo sapiens)
SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers (Homo sapiens)
GDP [cytosol]
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants (Homo sapiens)
SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors (Homo sapiens)
GDP [cytosol]
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
GDP [cytosol]
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
An unknown GEF exchanges GTP for GDP on CDC42:GDP (Homo sapiens)
GDP [cytosol]
DOCK180 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
GDP [cytosol]
p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
GDP [cytosol]
Drug ADME (Homo sapiens)
Azathioprine ADME (Homo sapiens)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Homo sapiens)
GDP [cytosol]
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
Tie2 Signaling (Homo sapiens)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Homo sapiens)
GDP [cytosol]
Platelet activation, signaling and aggregation (Homo sapiens)
GPVI-mediated activation cascade (Homo sapiens)
VAV1 is a GEF for Rho/Rac family GTPases (Homo sapiens)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Homo sapiens)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Homo sapiens)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Homo sapiens)
Integrin signaling (Homo sapiens)
Activation of Rap1 by cytosolic GEFs (Homo sapiens)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Homo sapiens)
GDP [cytosol]
Signal amplification (Homo sapiens)
ADP signalling through P2Y purinoceptor 1 (Homo sapiens)
Gq activation by P2Y purinoceptor 1 (Homo sapiens)
GDP [cytosol]
ADP signalling through P2Y purinoceptor 12 (Homo sapiens)
Gi activation by P2Y purinoceptor 12 (Homo sapiens)
GDP [cytosol]
Thromboxane signalling through TP receptor (Homo sapiens)
G13 activation by TP receptor (Homo sapiens)
GDP [cytosol]
Gq activation by TP receptor (Homo sapiens)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Homo sapiens)
Thrombin-activated PARs activate G12/13 (Homo sapiens)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Homo sapiens)
GDP [cytosol]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Disassembly of COPII coated vesicle (Homo sapiens)
GDP [cytosol]
Costimulation by the CD28 family (Homo sapiens)
CD28 co-stimulation (Homo sapiens)
CD28 dependent Vav1 pathway (Homo sapiens)
Activation of Cdc42 by pVav1 (Homo sapiens)
GDP [cytosol]
Activation of Rac1 by pVav1 (Homo sapiens)
GDP [cytosol]
MHC class II antigen presentation (Homo sapiens)
Internalization of MHC II:Ii clathrin coated vesicle (Homo sapiens)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)
GDP [cytosol]
Rap1 signalling (Homo sapiens)
Activation of Rap1 by cytosolic GEFs (Homo sapiens)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Homo sapiens)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Downstream signaling events of B Cell Receptor (BCR) (Homo sapiens)
Activation of RAS in B cells (Homo sapiens)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Homo sapiens)
GDP [cytosol]
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Homo sapiens)
GDP [cytosol]
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)
GDP [cytosol]
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CD209 (DC-SIGN) signaling (Homo sapiens)
CD209 activate GTPase RAS (Homo sapiens)
GDP [cytosol]
DAP12 interactions (Homo sapiens)
DAP12 signaling (Homo sapiens)
Activation of RAC1 by VAV2/3 (Homo sapiens)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Homo sapiens)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated MAPK activation (Homo sapiens)
Activation of RAC1 by VAV (Homo sapiens)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Homo sapiens)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)
GDP [cytosol]
Activation of RAC1 by VAV (Homo sapiens)
GDP [cytosol]
An unknown GEF exchanges GTP for GDP on CDC42:GDP (Homo sapiens)
GDP [cytosol]
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Glucagon signaling in metabolic regulation (Homo sapiens)
Glucagon:GCGR mediates GTP-GDP exchange (Homo sapiens)
GDP [cytosol]
Regulation of insulin secretion (Homo sapiens)
Acetylcholine regulates insulin secretion (Homo sapiens)
Muscarinic Acetylcholine Receptor M3 activates Gq (Homo sapiens)
GDP [cytosol]
Adrenaline,noradrenaline inhibits insulin secretion (Homo sapiens)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Homo sapiens)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Homo sapiens)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)
FFAR1:FFAR1 ligands activate Gq (Homo sapiens)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Homo sapiens)
GLP1R:GLP1 activates G(s) (Homo sapiens)
GDP [cytosol]
RAP1A exchanges GDP for GTP (Homo sapiens)
GDP [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
PCK1 phosphorylates OA to yield PEP (Homo sapiens)
GDP [cytosol]
Metabolism of nucleotides (Homo sapiens)
Nucleotide biosynthesis (Homo sapiens)
Purine ribonucleoside monophosphate biosynthesis (Homo sapiens)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Homo sapiens)
GDP [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
ALG11 transfers the fourth and fifth Man to the N-glycan precursor (Homo sapiens)
GDP [cytosol]
Addition of a second mannose to the N-glycan precursor by ALG2 (Homo sapiens)
GDP [cytosol]
Addition of a third mannose to the N-glycan precursor by ALG2 (Homo sapiens)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Homo sapiens)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
Synthesis of dolichyl-phosphate mannose (Homo sapiens)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Homo sapiens)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Homo sapiens)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
Synthesis of dolichyl-phosphate mannose (Homo sapiens)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Homo sapiens)
GDP [cytosol]
Translation (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
Cap-dependent Translation Initiation (Homo sapiens)
Recycling of eIF2:GDP (Homo sapiens)
eIF2 activation (Homo sapiens)
GDP [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
Activation of RAC1 downstream of NMDARs (Homo sapiens)
p-S516-ARHGEF7 activates RAC1 (Homo sapiens)
GDP [cytosol]
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Homo sapiens)
Ras activation upon Ca2+ influx through NMDA receptor (Homo sapiens)
NMDA-activated RASGRF1 activates RAS (Homo sapiens)
GDP [cytosol]
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Anchoring of the basal body to the plasma membrane (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Homo sapiens)
VxPx cargo-targeting to cilium (Homo sapiens)
GBF1 stimulates nucleotide exchange on ARF4 (Homo sapiens)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
GDP [cytosol]
Sensory Perception (Homo sapiens)
Olfactory Signaling Pathway (Homo sapiens)
GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 (Homo sapiens)
GDP [cytosol]
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
GDP [cytosol]
GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
GDP [cytosol]
GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
GDP [cytosol]
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Activation of the phototransduction cascade (Homo sapiens)
MII catalyses GDP/GTP exchange on Gt (Homo sapiens)
GDP [cytosol]
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GDP [cytosol]
Integrin signaling (Homo sapiens)
Activation of Rap1 by cytosolic GEFs (Homo sapiens)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Homo sapiens)
GDP [cytosol]
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Intrinsic nucleotide exchange on RAS (Homo sapiens)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
RAS processing (Homo sapiens)
mature p21 RAS binds GDP (Homo sapiens)
GDP [cytosol]
MTOR signalling (Homo sapiens)
GTP loading by Rheb (Homo sapiens)
GDP [cytosol]
Signaling by Erythropoietin (Homo sapiens)
Erythropoietin activates RAS (Homo sapiens)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)
GDP [cytosol]
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Homo sapiens)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Homo sapiens)
GDP [cytosol]
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
GDP [cytosol]
Opioid Signalling (Homo sapiens)
G-protein activation (Homo sapiens)
G-protein alpha subunit is inactivated (Homo sapiens)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Homo sapiens)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Homo sapiens)
GDP [cytosol]
G alpha (q) signalling events (Homo sapiens)
Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens)
EGFR Transactivation by Gastrin (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Homo sapiens)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
GDP [cytosol]
G alpha (s) signalling events (Homo sapiens)
GPER1 signaling (Homo sapiens)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Homo sapiens)
GDP [cytosol]
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GDP [cytosol]
G alpha (z) signalling events (Homo sapiens)
Liganded Gz-activating GPCR acts as a GEF for Gz (Homo sapiens)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PTK6 (Homo sapiens)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Homo sapiens)
Activation of RAC1 by the PXN:CRK complex (Homo sapiens)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by EGFR (Homo sapiens)
GRB2 events in EGFR signaling (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Homo sapiens)
GDP [cytosol]
SHC1 events in EGFR signaling (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Homo sapiens)
GDP [cytosol]
Signaling by ERBB2 (Homo sapiens)
GRB2 events in ERBB2 signaling (Homo sapiens)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Homo sapiens)
GDP [cytosol]
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers. (Homo sapiens)
GDP [cytosol]
SHC1 events in ERBB2 signaling (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers (Homo sapiens)
GDP [cytosol]
Signaling by ERBB4 (Homo sapiens)
SHC1 events in ERBB4 signaling (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Homo sapiens)
GDP [cytosol]
Signaling by FGFR (Homo sapiens)
Signaling by FGFR1 (Homo sapiens)
Downstream signaling of activated FGFR1 (Homo sapiens)
FRS-mediated FGFR1 signaling (Homo sapiens)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Homo sapiens)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by FGFR2 (Homo sapiens)
Downstream signaling of activated FGFR2 (Homo sapiens)
FRS-mediated FGFR2 signaling (Homo sapiens)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Homo sapiens)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by FGFR3 (Homo sapiens)
Downstream signaling of activated FGFR3 (Homo sapiens)
FRS-mediated FGFR3 signaling (Homo sapiens)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Homo sapiens)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by FGFR4 (Homo sapiens)
Downstream signaling of activated FGFR4 (Homo sapiens)
FRS-mediated FGFR4 signaling (Homo sapiens)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Homo sapiens)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
GDP [cytosol]
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor signalling cascade (Homo sapiens)
GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)
GDP [cytosol]
IRS-mediated signalling (Homo sapiens)
SOS-mediated signalling (Homo sapiens)
GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS (Homo sapiens)
GDP [cytosol]
Signaling by MET (Homo sapiens)
MET activates RAS signaling (Homo sapiens)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Homo sapiens)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Homo sapiens)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Homo sapiens)
GDP [cytosol]
MET promotes cell motility (Homo sapiens)
MET activates RAP1 and RAC1 (Homo sapiens)
DOCK7 activates RAC1 (Homo sapiens)
GDP [cytosol]
RAPGEF1 activates RAP1 (Homo sapiens)
GDP [cytosol]
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Retrograde neurotrophin signalling (Homo sapiens)
Endocytosis (internalization) of clathrin-coated vesicle (Homo sapiens)
GDP [cytosol]
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
ARMS-mediated activation (Homo sapiens)
C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
GDP [cytosol]
Frs2-mediated activation (Homo sapiens)
(Frs2)C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
GDP [cytosol]
Signalling to RAS (Homo sapiens)
GRB2-1:SOS1:p-Y-SHC mediated nucleotide exchange of RAS (Homo sapiens)
GDP [cytosol]
p38MAPK events (Homo sapiens)
Guanine nucleotide exchange on RAL (Homo sapiens)
GDP [cytosol]
Signalling to p38 via RIT and RIN (Homo sapiens)
RIT/RIN are activated (Homo sapiens)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Homo sapiens)
Activated NTRK2 signals through CDK5 (Homo sapiens)
NTRK2 and CDK5 promote activation of RAC1 by TIAM1 (Homo sapiens)
GDP [cytosol]
Activated NTRK2 signals through FRS2 and FRS3 (Homo sapiens)
NTRK2 activates RAS signaling through FRS2 (Homo sapiens)
GDP [cytosol]
Activated NTRK2 signals through FYN (Homo sapiens)
NTRK2 activates RAC1 (Homo sapiens)
DOCK3 activates RAC1 (Homo sapiens)
GDP [cytosol]
Activated NTRK2 signals through RAS (Homo sapiens)
NTRK2 activates RAS signaling through SHC1 (Homo sapiens)
GDP [cytosol]
Signaling by NTRK3 (TRKC) (Homo sapiens)
Activated NTRK3 signals through RAS (Homo sapiens)
NTRK3 activates RAS through SHC1 (Homo sapiens)
GDP [cytosol]
Signaling by PDGF (Homo sapiens)
Downstream signal transduction (Homo sapiens)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Homo sapiens)
GDP [cytosol]
Signaling by SCF-KIT (Homo sapiens)
Activation of RAC1 (Homo sapiens)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Homo sapiens)
GDP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
IGF1R signaling cascade (Homo sapiens)
IRS-related events triggered by IGF1R (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
SOS-mediated signalling (Homo sapiens)
GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS (Homo sapiens)
GDP [cytosol]
SHC-related events triggered by IGF1R (Homo sapiens)
GRB2-1:SOS1:p-3Y-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)
GDP [cytosol]
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Homo sapiens)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
GDP [cytosol]
VEGF induces CDC42 activation by unknown mechanism (Homo sapiens)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Miro GTPase Cycle (Homo sapiens)
RHOT1 GTPase cycle (Homo sapiens)
RHOT1 GEFs activate RHOT1 (Homo sapiens)
GDP [cytosol]
RHOT2 GTPase cycle (Homo sapiens)
RHOT2 GEFs activate RHOT2 (Homo sapiens)
GDP [cytosol]
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
GDP [cytosol]
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
GDP [cytosol]
RAC2 GTPase cycle (Homo sapiens)
RAC2 GEFs activate RAC2 (Homo sapiens)
GDP [cytosol]
RAC3 GTPase cycle (Homo sapiens)
RAC3 GEFs activate RAC3 (Homo sapiens)
GDP [cytosol]
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
GDP [cytosol]
RHOB GTPase cycle (Homo sapiens)
RHOB GEFs activate RHOB (Homo sapiens)
GDP [cytosol]
RHOC GTPase cycle (Homo sapiens)
RHOC GEFs activate RHOC (Homo sapiens)
GDP [cytosol]
RHOD GTPase cycle (Homo sapiens)
RHOD auto-activates (Homo sapiens)
GDP [cytosol]
RHOF GTPase cycle (Homo sapiens)
RHOF auto-activates (Homo sapiens)
GDP [cytosol]
RHOG GTPase cycle (Homo sapiens)
RHOG GEFs activate RHOG (Homo sapiens)
GDP [cytosol]
RHOJ GTPase cycle (Homo sapiens)
RHOJ GEFs activate RHOJ (Homo sapiens)
GDP [cytosol]
RHOQ GTPase cycle (Homo sapiens)
RHOQ GEFs activate RHOQ (Homo sapiens)
GDP [cytosol]
RHOU GTPase cycle (Homo sapiens)
RHOU auto-activates (Homo sapiens)
GDP [cytosol]
RHOV GTPase cycle (Homo sapiens)
RHOV binds GTP (Homo sapiens)
GDP [cytosol]
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
WNT:FZD complex promotes G-protein nucleotide exchange (Homo sapiens)
GDP [cytosol]
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Homo sapiens)
GDP [cytosol]
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Homo sapiens)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
GBF1 stimulates nucleotide exchange on ARF (Homo sapiens)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Homo sapiens)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Homo sapiens)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Homo sapiens)
GDP [cytosol]
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Homo sapiens)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Homo sapiens)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Homo sapiens)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Homo sapiens)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Homo sapiens)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Homo sapiens)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Homo sapiens)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Homo sapiens)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Homo sapiens)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Homo sapiens)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Homo sapiens)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Homo sapiens)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Homo sapiens)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Homo sapiens)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Homo sapiens)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Homo sapiens)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Homo sapiens)
GDP [cytosol]
trans-Golgi Network Coat Activation (Homo sapiens)
GDP [cytosol]
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Nuclear Envelope (NE) Reassembly (Mus musculus)
Postmitotic nuclear pore complex (NPC) reformation (Mus musculus)
RCC1 stimulates GDP to GTP exchange on RAN (Mus musculus)
GDP [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to starvation (Mus musculus)
Amino acids regulate mTORC1 (Mus musculus)
RRAGA,B exchanges GDP for GTP (Mus musculus)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Mus musculus)
GDP [cytosol]
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
EPH-Ephrin signaling (Mus musculus)
EPH-ephrin mediated repulsion of cells (Mus musculus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)
GDP [cytosol]
EPHA-mediated growth cone collapse (Mus musculus)
NGEF exchanges GTP for GDP on RHOA (Mus musculus)
GDP [cytosol]
EPHB-mediated forward signaling (Mus musculus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Mus musculus)
GDP [cytosol]
L1CAM interactions (Mus musculus)
Recycling pathway of L1 (Mus musculus)
Formation of clathrin coated vesicle (Mus musculus)
GDP [cytosol]
Signal transduction by L1 (Mus musculus)
Activation of Rac1 by VAV2 (Mus musculus)
GDP [cytosol]
NCAM signaling for neurite out-growth (Mus musculus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Mus musculus)
GDP [cytosol]
Netrin-1 signaling (Mus musculus)
DCC mediated attractive signaling (Mus musculus)
Activation of Cdc42 (Mus musculus)
GDP [cytosol]
Activation of Rac1 (Mus musculus)
GDP [cytosol]
Semaphorin interactions (Mus musculus)
Sema4D in semaphorin signaling (Mus musculus)
Sema4D induced cell migration and growth-cone collapse (Mus musculus)
Activation of Rho by LARG and PDZ-RhoGEF (Mus musculus)
GDP [cytosol]
Drug ADME (Mus musculus)
Azathioprine ADME (Mus musculus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Mus musculus)
GDP [cytosol]
Hemostasis (Mus musculus)
Cell surface interactions at the vascular wall (Mus musculus)
Tie2 Signaling (Mus musculus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Mus musculus)
GDP [cytosol]
Platelet activation, signaling and aggregation (Mus musculus)
GPVI-mediated activation cascade (Mus musculus)
VAV1 is a GEF for Rho/Rac family GTPases (Mus musculus)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Mus musculus)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Mus musculus)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Mus musculus)
Integrin signaling (Mus musculus)
Activation of Rap1 by cytosolic GEFs (Mus musculus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
GDP [cytosol]
Signal amplification (Mus musculus)
ADP signalling through P2Y purinoceptor 12 (Mus musculus)
Gi activation by P2Y purinoceptor 12 (Mus musculus)
GDP [cytosol]
Thromboxane signalling through TP receptor (Mus musculus)
G13 activation by TP receptor (Mus musculus)
GDP [cytosol]
Gq activation by TP receptor (Mus musculus)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Mus musculus)
Thrombin-activated PARs activate G12/13 (Mus musculus)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Mus musculus)
GDP [cytosol]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
Disassembly of COPII coated vesicle (Mus musculus)
GDP [cytosol]
Costimulation by the CD28 family (Mus musculus)
CD28 co-stimulation (Mus musculus)
CD28 dependent Vav1 pathway (Mus musculus)
Activation of Cdc42 by pVav1 (Mus musculus)
GDP [cytosol]
Activation of Rac1 by pVav1 (Mus musculus)
GDP [cytosol]
MHC class II antigen presentation (Mus musculus)
Internalization of MHC II:Ii clathrin coated vesicle (Mus musculus)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Mus musculus)
GDP [cytosol]
Rap1 signalling (Mus musculus)
Activation of Rap1 by cytosolic GEFs (Mus musculus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of RAS in B cells (Mus musculus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Mus musculus)
GDP [cytosol]
Cytokine Signaling in Immune system (Mus musculus)
FLT3 Signaling (Mus musculus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Mus musculus)
GDP [cytosol]
Innate Immune System (Mus musculus)
DAP12 interactions (Mus musculus)
DAP12 signaling (Mus musculus)
Activation of RAC1 by VAV2/3 (Mus musculus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Mus musculus)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated MAPK activation (Mus musculus)
Activation of RAC1 by VAV (Mus musculus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Mus musculus)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Regulation of actin dynamics for phagocytic cup formation (Mus musculus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Mus musculus)
GDP [cytosol]
Activation of RAC1 by VAV (Mus musculus)
GDP [cytosol]
Metabolism (Mus musculus)
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Adrenaline,noradrenaline inhibits insulin secretion (Mus musculus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Mus musculus)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Mus musculus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Mus musculus)
FFAR1:FFAR1 ligands activate Gq (Mus musculus)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Mus musculus)
RAP1A exchanges GDP for GTP (Mus musculus)
GDP [cytosol]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
PCK1 phosphorylates OA to yield PEP (Mus musculus)
GDP [cytosol]
Metabolism of nucleotides (Mus musculus)
Nucleotide biosynthesis (Mus musculus)
Purine ribonucleoside monophosphate biosynthesis (Mus musculus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Mus musculus)
GDP [cytosol]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Mus musculus)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Mus musculus)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Mus musculus)
Synthesis of dolichyl-phosphate mannose (Mus musculus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Mus musculus)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Mus musculus)
ER to Golgi Anterograde Transport (Mus musculus)
COPII-mediated vesicle transport (Mus musculus)
Nucleotide exchange on RAB1 (Mus musculus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Mus musculus)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Mus musculus)
Synthesis of dolichyl-phosphate mannose (Mus musculus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Mus musculus)
GDP [cytosol]
Translation (Mus musculus)
Eukaryotic Translation Initiation (Mus musculus)
Cap-dependent Translation Initiation (Mus musculus)
Recycling of eIF2:GDP (Mus musculus)
eIF2 activation (Mus musculus)
GDP [cytosol]
Organelle biogenesis and maintenance (Mus musculus)
Cilium Assembly (Mus musculus)
Anchoring of the basal body to the plasma membrane (Mus musculus)
RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Mus musculus)
VxPx cargo-targeting to cilium (Mus musculus)
GBF1 stimulates nucleotide exchange on ARF4 (Mus musculus)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
GDP [cytosol]
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRAGE signals death through JNK (Mus musculus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)
GDP [cytosol]
Integrin signaling (Mus musculus)
Activation of Rap1 by cytosolic GEFs (Mus musculus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
GDP [cytosol]
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
Intrinsic nucleotide exchange on RAS (Mus musculus)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
RAS processing (Mus musculus)
mature p21 RAS binds GDP (Mus musculus)
GDP [cytosol]
MTOR signalling (Mus musculus)
GTP loading by Rheb (Mus musculus)
GDP [cytosol]
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
GEFs activate RhoA,B,C (Mus musculus)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Mus musculus)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Mus musculus)
GDP [cytosol]
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
GDP [cytosol]
Opioid Signalling (Mus musculus)
G-protein activation (Mus musculus)
G-protein alpha subunit is inactivated (Mus musculus)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Mus musculus)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Mus musculus)
GDP [cytosol]
G alpha (q) signalling events (Mus musculus)
Gastrin-CREB signalling pathway via PKC and MAPK (Mus musculus)
EGFR Transactivation by Gastrin (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Mus musculus)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
GDP [cytosol]
G alpha (s) signalling events (Mus musculus)
GPER1 signaling (Mus musculus)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Mus musculus)
GDP [cytosol]
Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
GDP [cytosol]
G alpha (z) signalling events (Mus musculus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Mus musculus)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Mus musculus)
Signaling by PTK6 (Mus musculus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Mus musculus)
Activation of RAC1 by the PXN:CRK complex (Mus musculus)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by EGFR (Mus musculus)
GRB2 events in EGFR signaling (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Mus musculus)
GDP [cytosol]
SHC1 events in EGFR signaling (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Mus musculus)
GDP [cytosol]
Signaling by ERBB2 (Mus musculus)
GRB2 events in ERBB2 signaling (Mus musculus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)
GDP [cytosol]
Signaling by ERBB4 (Mus musculus)
SHC1 events in ERBB4 signaling (Mus musculus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Mus musculus)
GDP [cytosol]
Signaling by FGFR (Mus musculus)
Signaling by FGFR1 (Mus musculus)
Downstream signaling of activated FGFR1 (Mus musculus)
FRS-mediated FGFR1 signaling (Mus musculus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Mus musculus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Signaling by FGFR2 (Mus musculus)
Downstream signaling of activated FGFR2 (Mus musculus)
FRS-mediated FGFR2 signaling (Mus musculus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Mus musculus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Signaling by FGFR3 (Mus musculus)
Downstream signaling of activated FGFR3 (Mus musculus)
FRS-mediated FGFR3 signaling (Mus musculus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Mus musculus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Signaling by FGFR4 (Mus musculus)
Downstream signaling of activated FGFR4 (Mus musculus)
FRS-mediated FGFR4 signaling (Mus musculus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Mus musculus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
GDP [cytosol]
Signaling by MET (Mus musculus)
MET activates RAS signaling (Mus musculus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Mus musculus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Mus musculus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Mus musculus)
GDP [cytosol]
MET promotes cell motility (Mus musculus)
MET activates RAP1 and RAC1 (Mus musculus)
DOCK7 activates RAC1 (Mus musculus)
GDP [cytosol]
RAPGEF1 activates RAP1 (Mus musculus)
GDP [cytosol]
Signaling by NTRKs (Mus musculus)
Signaling by NTRK1 (TRKA) (Mus musculus)
Signalling to ERKs (Mus musculus)
Prolonged ERK activation events (Mus musculus)
ARMS-mediated activation (Mus musculus)
C3G stimulates nucleotide exchange on Rap1 (Mus musculus)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Mus musculus)
Activated NTRK2 signals through FYN (Mus musculus)
NTRK2 activates RAC1 (Mus musculus)
DOCK3 activates RAC1 (Mus musculus)
GDP [cytosol]
Signaling by PDGF (Mus musculus)
Downstream signal transduction (Mus musculus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Mus musculus)
GDP [cytosol]
Signaling by SCF-KIT (Mus musculus)
Activation of RAC1 (Mus musculus)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Mus musculus)
GDP [cytosol]
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Mus musculus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
CDC42 GTPase cycle (Mus musculus)
CDC42 GEFs activate CDC42 (Mus musculus)
GDP [cytosol]
RAC1 GTPase cycle (Mus musculus)
RAC1 GEFs activate RAC1 (Mus musculus)
GDP [cytosol]
RAC2 GTPase cycle (Mus musculus)
RAC2 GEFs activate RAC2 (Mus musculus)
GDP [cytosol]
RAC3 GTPase cycle (Mus musculus)
RAC3 GEFs activate RAC3 (Mus musculus)
GDP [cytosol]
RHOA GTPase cycle (Mus musculus)
RHOA GEFs activate RHOA (Mus musculus)
GDP [cytosol]
RHOB GTPase cycle (Mus musculus)
RHOB GEFs activate RHOB (Mus musculus)
GDP [cytosol]
RHOC GTPase cycle (Mus musculus)
RHOC GEFs activate RHOC (Mus musculus)
GDP [cytosol]
RHOD GTPase cycle (Mus musculus)
RHOD auto-activates (Mus musculus)
GDP [cytosol]
RHOF GTPase cycle (Mus musculus)
RHOF auto-activates (Mus musculus)
GDP [cytosol]
RHOG GTPase cycle (Mus musculus)
RHOG GEFs activate RHOG (Mus musculus)
GDP [cytosol]
RHOJ GTPase cycle (Mus musculus)
RHOJ GEFs activate RHOJ (Mus musculus)
GDP [cytosol]
RHOQ GTPase cycle (Mus musculus)
RHOQ GEFs activate RHOQ (Mus musculus)
GDP [cytosol]
RHOU GTPase cycle (Mus musculus)
RHOU auto-activates (Mus musculus)
GDP [cytosol]
RHOV GTPase cycle (Mus musculus)
RHOV binds GTP (Mus musculus)
GDP [cytosol]
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
Ca2+ pathway (Mus musculus)
WNT:FZD complex promotes G-protein nucleotide exchange (Mus musculus)
GDP [cytosol]
Transport of small molecules (Mus musculus)
Aquaporin-mediated transport (Mus musculus)
Vasopressin regulates renal water homeostasis via Aquaporins (Mus musculus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Mus musculus)
GDP [cytosol]
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
ER to Golgi Anterograde Transport (Mus musculus)
COPII-mediated vesicle transport (Mus musculus)
Nucleotide exchange on RAB1 (Mus musculus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Mus musculus)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Mus musculus)
Golgi-to-ER retrograde transport (Mus musculus)
COPI-dependent Golgi-to-ER retrograde traffic (Mus musculus)
GBF1 stimulates nucleotide exchange on ARF (Mus musculus)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Mus musculus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Mus musculus)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Mus musculus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Mus musculus)
GDP [cytosol]
Rab regulation of trafficking (Mus musculus)
RAB GEFs exchange GTP for GDP on RABs (Mus musculus)
DENND1s exchange GTP for GDP on RAB35 (Mus musculus)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Mus musculus)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Mus musculus)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Mus musculus)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Mus musculus)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Mus musculus)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Mus musculus)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Mus musculus)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Mus musculus)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Mus musculus)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Mus musculus)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Mus musculus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Mus musculus)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Mus musculus)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Mus musculus)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Mus musculus)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Mus musculus)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Mus musculus)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Mus musculus)
Golgi Associated Vesicle Biogenesis (Mus musculus)
trans-Golgi Network Vesicle Scission (Mus musculus)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Mus musculus)
trans-Golgi Network Lysosomal Vesicle Scission (Mus musculus)
GDP [cytosol]
trans-Golgi Network Coat Activation (Mus musculus)
GDP [cytosol]
Mycobacterium tuberculosis biological processes (Mycobacterium tuberculosis)
Sulfur compound metabolism (Mycobacterium tuberculosis)
Sulfate assimilation (Mycobacterium tuberculosis)
APS is phosphorylated to PAPS (Mycobacterium tuberculosis)
GDP [cytosol]
Cell Cycle (Plasmodium falciparum)
Cell Cycle, Mitotic (Plasmodium falciparum)
M Phase (Plasmodium falciparum)
Mitotic Metaphase and Anaphase (Plasmodium falciparum)
Mitotic Anaphase (Plasmodium falciparum)
Nuclear Envelope (NE) Reassembly (Plasmodium falciparum)
Postmitotic nuclear pore complex (NPC) reformation (Plasmodium falciparum)
RCC1 stimulates GDP to GTP exchange on RAN (Plasmodium falciparum)
GDP [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide biosynthesis (Plasmodium falciparum)
Purine ribonucleoside monophosphate biosynthesis (Plasmodium falciparum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Plasmodium falciparum)
GDP [cytosol]
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Asparagine N-linked glycosylation (Plasmodium falciparum)
Transport to the Golgi and subsequent modification (Plasmodium falciparum)
ER to Golgi Anterograde Transport (Plasmodium falciparum)
COPII-mediated vesicle transport (Plasmodium falciparum)
Nucleotide exchange on RAB1 (Plasmodium falciparum)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Plasmodium falciparum)
GDP [cytosol]
Translation (Plasmodium falciparum)
Eukaryotic Translation Initiation (Plasmodium falciparum)
Cap-dependent Translation Initiation (Plasmodium falciparum)
Recycling of eIF2:GDP (Plasmodium falciparum)
eIF2 activation (Plasmodium falciparum)
GDP [cytosol]
Organelle biogenesis and maintenance (Plasmodium falciparum)
Cilium Assembly (Plasmodium falciparum)
Cargo trafficking to the periciliary membrane (Plasmodium falciparum)
VxPx cargo-targeting to cilium (Plasmodium falciparum)
GBF1 stimulates nucleotide exchange on ARF4 (Plasmodium falciparum)
GDP [cytosol]
Vesicle-mediated transport (Plasmodium falciparum)
Membrane Trafficking (Plasmodium falciparum)
ER to Golgi Anterograde Transport (Plasmodium falciparum)
COPII-mediated vesicle transport (Plasmodium falciparum)
Nucleotide exchange on RAB1 (Plasmodium falciparum)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Plasmodium falciparum)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Plasmodium falciparum)
Golgi-to-ER retrograde transport (Plasmodium falciparum)
COPI-dependent Golgi-to-ER retrograde traffic (Plasmodium falciparum)
GBF1 stimulates nucleotide exchange on ARF (Plasmodium falciparum)
GDP [cytosol]
Rab regulation of trafficking (Plasmodium falciparum)
RAB GEFs exchange GTP for GDP on RABs (Plasmodium falciparum)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Plasmodium falciparum)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Plasmodium falciparum)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Plasmodium falciparum)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Plasmodium falciparum)
trans-Golgi Network Coat Activation (Plasmodium falciparum)
GDP [cytosol]
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Metaphase and Anaphase (Rattus norvegicus)
Mitotic Anaphase (Rattus norvegicus)
Nuclear Envelope (NE) Reassembly (Rattus norvegicus)
Postmitotic nuclear pore complex (NPC) reformation (Rattus norvegicus)
RCC1 stimulates GDP to GTP exchange on RAN (Rattus norvegicus)
GDP [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to starvation (Rattus norvegicus)
Amino acids regulate mTORC1 (Rattus norvegicus)
RRAGA,B exchanges GDP for GTP (Rattus norvegicus)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Rattus norvegicus)
GDP [cytosol]
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
EPH-Ephrin signaling (Rattus norvegicus)
EPH-ephrin mediated repulsion of cells (Rattus norvegicus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
GDP [cytosol]
EPHA-mediated growth cone collapse (Rattus norvegicus)
NGEF exchanges GTP for GDP on RHOA (Rattus norvegicus)
GDP [cytosol]
EPHB-mediated forward signaling (Rattus norvegicus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Rattus norvegicus)
GDP [cytosol]
L1CAM interactions (Rattus norvegicus)
Recycling pathway of L1 (Rattus norvegicus)
Formation of clathrin coated vesicle (Rattus norvegicus)
GDP [cytosol]
Signal transduction by L1 (Rattus norvegicus)
Activation of Rac1 by VAV2 (Rattus norvegicus)
GDP [cytosol]
NCAM signaling for neurite out-growth (Rattus norvegicus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Rattus norvegicus)
GDP [cytosol]
Netrin-1 signaling (Rattus norvegicus)
DCC mediated attractive signaling (Rattus norvegicus)
Activation of Cdc42 (Rattus norvegicus)
GDP [cytosol]
Activation of Rac1 (Rattus norvegicus)
GDP [cytosol]
Semaphorin interactions (Rattus norvegicus)
Sema4D in semaphorin signaling (Rattus norvegicus)
Sema4D induced cell migration and growth-cone collapse (Rattus norvegicus)
Activation of Rho by LARG and PDZ-RhoGEF (Rattus norvegicus)
GDP [cytosol]
Drug ADME (Rattus norvegicus)
Azathioprine ADME (Rattus norvegicus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Rattus norvegicus)
GDP [cytosol]
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
Tie2 Signaling (Rattus norvegicus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Rattus norvegicus)
GDP [cytosol]
Platelet activation, signaling and aggregation (Rattus norvegicus)
GPVI-mediated activation cascade (Rattus norvegicus)
VAV1 is a GEF for Rho/Rac family GTPases (Rattus norvegicus)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Rattus norvegicus)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Rattus norvegicus)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Rattus norvegicus)
Integrin signaling (Rattus norvegicus)
Activation of Rap1 by cytosolic GEFs (Rattus norvegicus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Rattus norvegicus)
GDP [cytosol]
Signal amplification (Rattus norvegicus)
ADP signalling through P2Y purinoceptor 12 (Rattus norvegicus)
Gi activation by P2Y purinoceptor 12 (Rattus norvegicus)
GDP [cytosol]
Thromboxane signalling through TP receptor (Rattus norvegicus)
G13 activation by TP receptor (Rattus norvegicus)
GDP [cytosol]
Gq activation by TP receptor (Rattus norvegicus)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Rattus norvegicus)
Thrombin-activated PARs activate G12/13 (Rattus norvegicus)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Rattus norvegicus)
GDP [cytosol]
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Rattus norvegicus)
Disassembly of COPII coated vesicle (Rattus norvegicus)
GDP [cytosol]
Costimulation by the CD28 family (Rattus norvegicus)
CD28 co-stimulation (Rattus norvegicus)
CD28 dependent Vav1 pathway (Rattus norvegicus)
Activation of Cdc42 by pVav1 (Rattus norvegicus)
GDP [cytosol]
Activation of Rac1 by pVav1 (Rattus norvegicus)
GDP [cytosol]
MHC class II antigen presentation (Rattus norvegicus)
Internalization of MHC II:Ii clathrin coated vesicle (Rattus norvegicus)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Rattus norvegicus)
GDP [cytosol]
Rap1 signalling (Rattus norvegicus)
Activation of Rap1 by cytosolic GEFs (Rattus norvegicus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Rattus norvegicus)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Downstream signaling events of B Cell Receptor (BCR) (Rattus norvegicus)
Activation of RAS in B cells (Rattus norvegicus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Rattus norvegicus)
GDP [cytosol]
Cytokine Signaling in Immune system (Rattus norvegicus)
FLT3 Signaling (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Rattus norvegicus)
GDP [cytosol]
Innate Immune System (Rattus norvegicus)
DAP12 interactions (Rattus norvegicus)
DAP12 signaling (Rattus norvegicus)
Activation of RAC1 by VAV2/3 (Rattus norvegicus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Rattus norvegicus)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
FCERI mediated MAPK activation (Rattus norvegicus)
Activation of RAC1 by VAV (Rattus norvegicus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Rattus norvegicus)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Rattus norvegicus)
GDP [cytosol]
Activation of RAC1 by VAV (Rattus norvegicus)
GDP [cytosol]
Metabolism (Rattus norvegicus)
Integration of energy metabolism (Rattus norvegicus)
Regulation of insulin secretion (Rattus norvegicus)
Adrenaline,noradrenaline inhibits insulin secretion (Rattus norvegicus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Rattus norvegicus)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Rattus norvegicus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Rattus norvegicus)
FFAR1:FFAR1 ligands activate Gq (Rattus norvegicus)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Rattus norvegicus)
RAP1A exchanges GDP for GTP (Rattus norvegicus)
GDP [cytosol]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
PCK1 phosphorylates OA to yield PEP (Rattus norvegicus)
GDP [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide biosynthesis (Rattus norvegicus)
Purine ribonucleoside monophosphate biosynthesis (Rattus norvegicus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Rattus norvegicus)
GDP [cytosol]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Rattus norvegicus)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Rattus norvegicus)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Rattus norvegicus)
Synthesis of dolichyl-phosphate mannose (Rattus norvegicus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Rattus norvegicus)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Rattus norvegicus)
ER to Golgi Anterograde Transport (Rattus norvegicus)
COPII-mediated vesicle transport (Rattus norvegicus)
Nucleotide exchange on RAB1 (Rattus norvegicus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Rattus norvegicus)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Rattus norvegicus)
Synthesis of dolichyl-phosphate mannose (Rattus norvegicus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Rattus norvegicus)
GDP [cytosol]
Translation (Rattus norvegicus)
Eukaryotic Translation Initiation (Rattus norvegicus)
Cap-dependent Translation Initiation (Rattus norvegicus)
Recycling of eIF2:GDP (Rattus norvegicus)
eIF2 activation (Rattus norvegicus)
GDP [cytosol]
Organelle biogenesis and maintenance (Rattus norvegicus)
Cilium Assembly (Rattus norvegicus)
Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Rattus norvegicus)
VxPx cargo-targeting to cilium (Rattus norvegicus)
GBF1 stimulates nucleotide exchange on ARF4 (Rattus norvegicus)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
GDP [cytosol]
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
p75 NTR receptor-mediated signalling (Rattus norvegicus)
Cell death signalling via NRAGE, NRIF and NADE (Rattus norvegicus)
NRAGE signals death through JNK (Rattus norvegicus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Rattus norvegicus)
GDP [cytosol]
Integrin signaling (Rattus norvegicus)
Activation of Rap1 by cytosolic GEFs (Rattus norvegicus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Rattus norvegicus)
GDP [cytosol]
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
Intrinsic nucleotide exchange on RAS (Rattus norvegicus)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
RAS processing (Rattus norvegicus)
mature p21 RAS binds GDP (Rattus norvegicus)
GDP [cytosol]
MTOR signalling (Rattus norvegicus)
GTP loading by Rheb (Rattus norvegicus)
GDP [cytosol]
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (12/13) signalling events (Rattus norvegicus)
GEFs activate RhoA,B,C (Rattus norvegicus)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Rattus norvegicus)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Rattus norvegicus)
GDP [cytosol]
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
GDP [cytosol]
Opioid Signalling (Rattus norvegicus)
G-protein activation (Rattus norvegicus)
G-protein alpha subunit is inactivated (Rattus norvegicus)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Rattus norvegicus)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Rattus norvegicus)
GDP [cytosol]
G alpha (q) signalling events (Rattus norvegicus)
Gastrin-CREB signalling pathway via PKC and MAPK (Rattus norvegicus)
EGFR Transactivation by Gastrin (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Rattus norvegicus)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
GDP [cytosol]
G alpha (z) signalling events (Rattus norvegicus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Rattus norvegicus)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PTK6 (Rattus norvegicus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Rattus norvegicus)
Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
GRB2 events in EGFR signaling (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Rattus norvegicus)
GDP [cytosol]
SHC1 events in EGFR signaling (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Rattus norvegicus)
GDP [cytosol]
Signaling by ERBB2 (Rattus norvegicus)
GRB2 events in ERBB2 signaling (Rattus norvegicus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)
GDP [cytosol]
Signaling by ERBB4 (Rattus norvegicus)
SHC1 events in ERBB4 signaling (Rattus norvegicus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Rattus norvegicus)
GDP [cytosol]
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Downstream signaling of activated FGFR1 (Rattus norvegicus)
FRS-mediated FGFR1 signaling (Rattus norvegicus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Signaling by FGFR2 (Rattus norvegicus)
Downstream signaling of activated FGFR2 (Rattus norvegicus)
FRS-mediated FGFR2 signaling (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Rattus norvegicus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Signaling by FGFR3 (Rattus norvegicus)
Downstream signaling of activated FGFR3 (Rattus norvegicus)
FRS-mediated FGFR3 signaling (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Rattus norvegicus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Signaling by FGFR4 (Rattus norvegicus)
Downstream signaling of activated FGFR4 (Rattus norvegicus)
FRS-mediated FGFR4 signaling (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Rattus norvegicus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Signaling by MET (Rattus norvegicus)
MET activates RAS signaling (Rattus norvegicus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Rattus norvegicus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Rattus norvegicus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Rattus norvegicus)
GDP [cytosol]
MET promotes cell motility (Rattus norvegicus)
MET activates RAP1 and RAC1 (Rattus norvegicus)
DOCK7 activates RAC1 (Rattus norvegicus)
GDP [cytosol]
RAPGEF1 activates RAP1 (Rattus norvegicus)
GDP [cytosol]
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
Signalling to ERKs (Rattus norvegicus)
Prolonged ERK activation events (Rattus norvegicus)
ARMS-mediated activation (Rattus norvegicus)
C3G stimulates nucleotide exchange on Rap1 (Rattus norvegicus)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Rattus norvegicus)
Activated NTRK2 signals through FYN (Rattus norvegicus)
NTRK2 activates RAC1 (Rattus norvegicus)
DOCK3 activates RAC1 (Rattus norvegicus)
GDP [cytosol]
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Rattus norvegicus)
GDP [cytosol]
Signaling by SCF-KIT (Rattus norvegicus)
Activation of RAC1 (Rattus norvegicus)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Rattus norvegicus)
GDP [cytosol]
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Rattus norvegicus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase cycle (Rattus norvegicus)
CDC42 GTPase cycle (Rattus norvegicus)
CDC42 GEFs activate CDC42 (Rattus norvegicus)
GDP [cytosol]
RAC1 GTPase cycle (Rattus norvegicus)
RAC1 GEFs activate RAC1 (Rattus norvegicus)
GDP [cytosol]
RAC2 GTPase cycle (Rattus norvegicus)
RAC2 GEFs activate RAC2 (Rattus norvegicus)
GDP [cytosol]
RHOA GTPase cycle (Rattus norvegicus)
RHOA GEFs activate RHOA (Rattus norvegicus)
GDP [cytosol]
RHOB GTPase cycle (Rattus norvegicus)
RHOB GEFs activate RHOB (Rattus norvegicus)
GDP [cytosol]
RHOD GTPase cycle (Rattus norvegicus)
RHOD auto-activates (Rattus norvegicus)
GDP [cytosol]
RHOF GTPase cycle (Rattus norvegicus)
RHOF auto-activates (Rattus norvegicus)
GDP [cytosol]
RHOG GTPase cycle (Rattus norvegicus)
RHOG GEFs activate RHOG (Rattus norvegicus)
GDP [cytosol]
RHOJ GTPase cycle (Rattus norvegicus)
RHOJ GEFs activate RHOJ (Rattus norvegicus)
GDP [cytosol]
RHOQ GTPase cycle (Rattus norvegicus)
RHOQ GEFs activate RHOQ (Rattus norvegicus)
GDP [cytosol]
RHOU GTPase cycle (Rattus norvegicus)
RHOU auto-activates (Rattus norvegicus)
GDP [cytosol]
RHOV GTPase cycle (Rattus norvegicus)
RHOV binds GTP (Rattus norvegicus)
GDP [cytosol]
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
Ca2+ pathway (Rattus norvegicus)
WNT:FZD complex promotes G-protein nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Transport of small molecules (Rattus norvegicus)
Aquaporin-mediated transport (Rattus norvegicus)
Vasopressin regulates renal water homeostasis via Aquaporins (Rattus norvegicus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Rattus norvegicus)
GDP [cytosol]
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
ER to Golgi Anterograde Transport (Rattus norvegicus)
COPII-mediated vesicle transport (Rattus norvegicus)
Nucleotide exchange on RAB1 (Rattus norvegicus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Rattus norvegicus)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Rattus norvegicus)
Golgi-to-ER retrograde transport (Rattus norvegicus)
COPI-dependent Golgi-to-ER retrograde traffic (Rattus norvegicus)
GBF1 stimulates nucleotide exchange on ARF (Rattus norvegicus)
GDP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Rattus norvegicus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Rattus norvegicus)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Rattus norvegicus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Rattus norvegicus)
GDP [cytosol]
Rab regulation of trafficking (Rattus norvegicus)
RAB GEFs exchange GTP for GDP on RABs (Rattus norvegicus)
DENND1s exchange GTP for GDP on RAB35 (Rattus norvegicus)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Rattus norvegicus)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Rattus norvegicus)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Rattus norvegicus)
GDP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Rattus norvegicus)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Rattus norvegicus)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Rattus norvegicus)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Rattus norvegicus)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Rattus norvegicus)
GDP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Rattus norvegicus)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Rattus norvegicus)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Rattus norvegicus)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Rattus norvegicus)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Rattus norvegicus)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Rattus norvegicus)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Rattus norvegicus)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Rattus norvegicus)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Rattus norvegicus)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Rattus norvegicus)
Golgi Associated Vesicle Biogenesis (Rattus norvegicus)
trans-Golgi Network Vesicle Scission (Rattus norvegicus)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Rattus norvegicus)
trans-Golgi Network Lysosomal Vesicle Scission (Rattus norvegicus)
GDP [cytosol]
trans-Golgi Network Coat Activation (Rattus norvegicus)
GDP [cytosol]
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
M Phase (Saccharomyces cerevisiae)
Mitotic Metaphase and Anaphase (Saccharomyces cerevisiae)
Mitotic Anaphase (Saccharomyces cerevisiae)
Nuclear Envelope (NE) Reassembly (Saccharomyces cerevisiae)
Postmitotic nuclear pore complex (NPC) reformation (Saccharomyces cerevisiae)
RCC1 stimulates GDP to GTP exchange on RAN (Saccharomyces cerevisiae)
GDP [cytosol]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to starvation (Saccharomyces cerevisiae)
Amino acids regulate mTORC1 (Saccharomyces cerevisiae)
RRAGC,D exchanges GTP for GDP (Saccharomyces cerevisiae)
GDP [cytosol]
Hemostasis (Saccharomyces cerevisiae)
Platelet activation, signaling and aggregation (Saccharomyces cerevisiae)
Platelet Aggregation (Plug Formation) (Saccharomyces cerevisiae)
Integrin signaling (Saccharomyces cerevisiae)
Activation of Rap1 by cytosolic GEFs (Saccharomyces cerevisiae)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Saccharomyces cerevisiae)
GDP [cytosol]
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
Rap1 signalling (Saccharomyces cerevisiae)
Activation of Rap1 by cytosolic GEFs (Saccharomyces cerevisiae)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Saccharomyces cerevisiae)
GDP [cytosol]
Metabolism (Saccharomyces cerevisiae)
Integration of energy metabolism (Saccharomyces cerevisiae)
Regulation of insulin secretion (Saccharomyces cerevisiae)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Saccharomyces cerevisiae)
RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)
GDP [cytosol]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide biosynthesis (Saccharomyces cerevisiae)
Purine ribonucleoside monophosphate biosynthesis (Saccharomyces cerevisiae)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Saccharomyces cerevisiae)
GDP [cytosol]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Saccharomyces cerevisiae)
Addition of a second mannose to the N-glycan precursor by ALG2 (Saccharomyces cerevisiae)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Saccharomyces cerevisiae)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Saccharomyces cerevisiae)
ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
COPII-mediated vesicle transport (Saccharomyces cerevisiae)
Nucleotide exchange on RAB1 (Saccharomyces cerevisiae)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Saccharomyces cerevisiae)
GDP [cytosol]
Translation (Saccharomyces cerevisiae)
Eukaryotic Translation Initiation (Saccharomyces cerevisiae)
Cap-dependent Translation Initiation (Saccharomyces cerevisiae)
Recycling of eIF2:GDP (Saccharomyces cerevisiae)
eIF2 activation (Saccharomyces cerevisiae)
GDP [cytosol]
Organelle biogenesis and maintenance (Saccharomyces cerevisiae)
Cilium Assembly (Saccharomyces cerevisiae)
Cargo trafficking to the periciliary membrane (Saccharomyces cerevisiae)
VxPx cargo-targeting to cilium (Saccharomyces cerevisiae)
GBF1 stimulates nucleotide exchange on ARF4 (Saccharomyces cerevisiae)
GDP [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
Integrin signaling (Saccharomyces cerevisiae)
Activation of Rap1 by cytosolic GEFs (Saccharomyces cerevisiae)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Saccharomyces cerevisiae)
GDP [cytosol]
MTOR signalling (Saccharomyces cerevisiae)
GTP loading by Rheb (Saccharomyces cerevisiae)
GDP [cytosol]
Signaling by GPCR (Saccharomyces cerevisiae)
GPCR downstream signalling (Saccharomyces cerevisiae)
G alpha (12/13) signalling events (Saccharomyces cerevisiae)
GEFs activate RhoA,B,C (Saccharomyces cerevisiae)
GDP [cytosol]
G alpha (i) signalling events (Saccharomyces cerevisiae)
Opioid Signalling (Saccharomyces cerevisiae)
G-protein activation (Saccharomyces cerevisiae)
G-protein alpha subunit is inactivated (Saccharomyces cerevisiae)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Saccharomyces cerevisiae)
Signaling by Rho GTPases (Saccharomyces cerevisiae)
RHO GTPase cycle (Saccharomyces cerevisiae)
CDC42 GTPase cycle (Saccharomyces cerevisiae)
CDC42 GEFs activate CDC42 (Saccharomyces cerevisiae)
GDP [cytosol]
RHOD GTPase cycle (Saccharomyces cerevisiae)
RHOD auto-activates (Saccharomyces cerevisiae)
GDP [cytosol]
RHOF GTPase cycle (Saccharomyces cerevisiae)
RHOF auto-activates (Saccharomyces cerevisiae)
GDP [cytosol]
RHOQ GTPase cycle (Saccharomyces cerevisiae)
RHOQ GEFs activate RHOQ (Saccharomyces cerevisiae)
GDP [cytosol]
RHOU GTPase cycle (Saccharomyces cerevisiae)
RHOU auto-activates (Saccharomyces cerevisiae)
GDP [cytosol]
RHOV GTPase cycle (Saccharomyces cerevisiae)
RHOV binds GTP (Saccharomyces cerevisiae)
GDP [cytosol]
Vesicle-mediated transport (Saccharomyces cerevisiae)
Membrane Trafficking (Saccharomyces cerevisiae)
ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
COPII-mediated vesicle transport (Saccharomyces cerevisiae)
Nucleotide exchange on RAB1 (Saccharomyces cerevisiae)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Saccharomyces cerevisiae)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Saccharomyces cerevisiae)
Golgi-to-ER retrograde transport (Saccharomyces cerevisiae)
COPI-dependent Golgi-to-ER retrograde traffic (Saccharomyces cerevisiae)
GBF1 stimulates nucleotide exchange on ARF (Saccharomyces cerevisiae)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Saccharomyces cerevisiae)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Saccharomyces cerevisiae)
GDP [cytosol]
Rab regulation of trafficking (Saccharomyces cerevisiae)
RAB GEFs exchange GTP for GDP on RABs (Saccharomyces cerevisiae)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Saccharomyces cerevisiae)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Saccharomyces cerevisiae)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Saccharomyces cerevisiae)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Saccharomyces cerevisiae)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Saccharomyces cerevisiae)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Saccharomyces cerevisiae)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Saccharomyces cerevisiae)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Saccharomyces cerevisiae)
trans-Golgi Network Coat Activation (Saccharomyces cerevisiae)
GDP [cytosol]
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
M Phase (Schizosaccharomyces pombe)
Mitotic Metaphase and Anaphase (Schizosaccharomyces pombe)
Mitotic Anaphase (Schizosaccharomyces pombe)
Nuclear Envelope (NE) Reassembly (Schizosaccharomyces pombe)
Postmitotic nuclear pore complex (NPC) reformation (Schizosaccharomyces pombe)
RCC1 stimulates GDP to GTP exchange on RAN (Schizosaccharomyces pombe)
GDP [cytosol]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to starvation (Schizosaccharomyces pombe)
Amino acids regulate mTORC1 (Schizosaccharomyces pombe)
RRAGA,B exchanges GDP for GTP (Schizosaccharomyces pombe)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Schizosaccharomyces pombe)
GDP [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide biosynthesis (Schizosaccharomyces pombe)
Purine ribonucleoside monophosphate biosynthesis (Schizosaccharomyces pombe)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Schizosaccharomyces pombe)
GDP [cytosol]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Asparagine N-linked glycosylation (Schizosaccharomyces pombe)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Schizosaccharomyces pombe)
Addition of a second mannose to the N-glycan precursor by ALG2 (Schizosaccharomyces pombe)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Schizosaccharomyces pombe)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Schizosaccharomyces pombe)
ER to Golgi Anterograde Transport (Schizosaccharomyces pombe)
COPII-mediated vesicle transport (Schizosaccharomyces pombe)
Nucleotide exchange on RAB1 (Schizosaccharomyces pombe)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Schizosaccharomyces pombe)
GDP [cytosol]
Translation (Schizosaccharomyces pombe)
Eukaryotic Translation Initiation (Schizosaccharomyces pombe)
Cap-dependent Translation Initiation (Schizosaccharomyces pombe)
Recycling of eIF2:GDP (Schizosaccharomyces pombe)
eIF2 activation (Schizosaccharomyces pombe)
GDP [cytosol]
Organelle biogenesis and maintenance (Schizosaccharomyces pombe)
Cilium Assembly (Schizosaccharomyces pombe)
Cargo trafficking to the periciliary membrane (Schizosaccharomyces pombe)
VxPx cargo-targeting to cilium (Schizosaccharomyces pombe)
GBF1 stimulates nucleotide exchange on ARF4 (Schizosaccharomyces pombe)
GDP [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
MTOR signalling (Schizosaccharomyces pombe)
GTP loading by Rheb (Schizosaccharomyces pombe)
GDP [cytosol]
Signaling by GPCR (Schizosaccharomyces pombe)
GPCR downstream signalling (Schizosaccharomyces pombe)
G alpha (12/13) signalling events (Schizosaccharomyces pombe)
GEFs activate RhoA,B,C (Schizosaccharomyces pombe)
GDP [cytosol]
G alpha (i) signalling events (Schizosaccharomyces pombe)
Opioid Signalling (Schizosaccharomyces pombe)
G-protein activation (Schizosaccharomyces pombe)
G-protein alpha subunit is inactivated (Schizosaccharomyces pombe)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Schizosaccharomyces pombe)
Signaling by Rho GTPases (Schizosaccharomyces pombe)
RHO GTPase cycle (Schizosaccharomyces pombe)
CDC42 GTPase cycle (Schizosaccharomyces pombe)
CDC42 GEFs activate CDC42 (Schizosaccharomyces pombe)
GDP [cytosol]
RHOD GTPase cycle (Schizosaccharomyces pombe)
RHOD auto-activates (Schizosaccharomyces pombe)
GDP [cytosol]
RHOF GTPase cycle (Schizosaccharomyces pombe)
RHOF auto-activates (Schizosaccharomyces pombe)
GDP [cytosol]
RHOQ GTPase cycle (Schizosaccharomyces pombe)
RHOQ GEFs activate RHOQ (Schizosaccharomyces pombe)
GDP [cytosol]
RHOU GTPase cycle (Schizosaccharomyces pombe)
RHOU auto-activates (Schizosaccharomyces pombe)
GDP [cytosol]
RHOV GTPase cycle (Schizosaccharomyces pombe)
RHOV binds GTP (Schizosaccharomyces pombe)
GDP [cytosol]
Vesicle-mediated transport (Schizosaccharomyces pombe)
Membrane Trafficking (Schizosaccharomyces pombe)
ER to Golgi Anterograde Transport (Schizosaccharomyces pombe)
COPII-mediated vesicle transport (Schizosaccharomyces pombe)
Nucleotide exchange on RAB1 (Schizosaccharomyces pombe)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Schizosaccharomyces pombe)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Schizosaccharomyces pombe)
Golgi-to-ER retrograde transport (Schizosaccharomyces pombe)
COPI-dependent Golgi-to-ER retrograde traffic (Schizosaccharomyces pombe)
GBF1 stimulates nucleotide exchange on ARF (Schizosaccharomyces pombe)
GDP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Schizosaccharomyces pombe)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Schizosaccharomyces pombe)
GDP [cytosol]
Rab regulation of trafficking (Schizosaccharomyces pombe)
RAB GEFs exchange GTP for GDP on RABs (Schizosaccharomyces pombe)
DENND3 exchanges GTP for GDP on RAB12 (Schizosaccharomyces pombe)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Schizosaccharomyces pombe)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Schizosaccharomyces pombe)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Schizosaccharomyces pombe)
GDP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Schizosaccharomyces pombe)
GDP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Schizosaccharomyces pombe)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Schizosaccharomyces pombe)
trans-Golgi Network Coat Activation (Schizosaccharomyces pombe)
GDP [cytosol]
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Nuclear Envelope (NE) Reassembly (Sus scrofa)
Postmitotic nuclear pore complex (NPC) reformation (Sus scrofa)
RCC1 stimulates GDP to GTP exchange on RAN (Sus scrofa)
GDP [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to starvation (Sus scrofa)
Amino acids regulate mTORC1 (Sus scrofa)
RRAGA,B exchanges GDP for GTP (Sus scrofa)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Sus scrofa)
GDP [cytosol]
Developmental Biology (Sus scrofa)
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
EPH-Ephrin signaling (Sus scrofa)
EPH-ephrin mediated repulsion of cells (Sus scrofa)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
GDP [cytosol]
EPHA-mediated growth cone collapse (Sus scrofa)
NGEF exchanges GTP for GDP on RHOA (Sus scrofa)
GDP [cytosol]
EPHB-mediated forward signaling (Sus scrofa)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Sus scrofa)
GDP [cytosol]
L1CAM interactions (Sus scrofa)
Recycling pathway of L1 (Sus scrofa)
Formation of clathrin coated vesicle (Sus scrofa)
GDP [cytosol]
Signal transduction by L1 (Sus scrofa)
Activation of Rac1 by VAV2 (Sus scrofa)
GDP [cytosol]
NCAM signaling for neurite out-growth (Sus scrofa)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Sus scrofa)
GDP [cytosol]
Semaphorin interactions (Sus scrofa)
Sema4D in semaphorin signaling (Sus scrofa)
Sema4D induced cell migration and growth-cone collapse (Sus scrofa)
Activation of Rho by LARG and PDZ-RhoGEF (Sus scrofa)
GDP [cytosol]
Drug ADME (Sus scrofa)
Azathioprine ADME (Sus scrofa)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Sus scrofa)
GDP [cytosol]
Hemostasis (Sus scrofa)
Cell surface interactions at the vascular wall (Sus scrofa)
Tie2 Signaling (Sus scrofa)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Sus scrofa)
GDP [cytosol]
Platelet activation, signaling and aggregation (Sus scrofa)
GPVI-mediated activation cascade (Sus scrofa)
VAV1 is a GEF for Rho/Rac family GTPases (Sus scrofa)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Sus scrofa)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Sus scrofa)
Integrin signaling (Sus scrofa)
Activation of Rap1 by cytosolic GEFs (Sus scrofa)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Sus scrofa)
GDP [cytosol]
Signal amplification (Sus scrofa)
ADP signalling through P2Y purinoceptor 12 (Sus scrofa)
Gi activation by P2Y purinoceptor 12 (Sus scrofa)
GDP [cytosol]
Thromboxane signalling through TP receptor (Sus scrofa)
G13 activation by TP receptor (Sus scrofa)
GDP [cytosol]
Gq activation by TP receptor (Sus scrofa)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Sus scrofa)
Thrombin-activated PARs activate G12/13 (Sus scrofa)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Sus scrofa)
GDP [cytosol]
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Sus scrofa)
Disassembly of COPII coated vesicle (Sus scrofa)
GDP [cytosol]
Costimulation by the CD28 family (Sus scrofa)
CD28 co-stimulation (Sus scrofa)
CD28 dependent Vav1 pathway (Sus scrofa)
Activation of Cdc42 by pVav1 (Sus scrofa)
GDP [cytosol]
Activation of Rac1 by pVav1 (Sus scrofa)
GDP [cytosol]
MHC class II antigen presentation (Sus scrofa)
Internalization of MHC II:Ii clathrin coated vesicle (Sus scrofa)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Sus scrofa)
GDP [cytosol]
Rap1 signalling (Sus scrofa)
Activation of Rap1 by cytosolic GEFs (Sus scrofa)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Sus scrofa)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Sus scrofa)
Downstream signaling events of B Cell Receptor (BCR) (Sus scrofa)
Activation of RAS in B cells (Sus scrofa)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Sus scrofa)
GDP [cytosol]
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Sus scrofa)
GDP [cytosol]
Innate Immune System (Sus scrofa)
DAP12 interactions (Sus scrofa)
DAP12 signaling (Sus scrofa)
Activation of RAC1 by VAV2/3 (Sus scrofa)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
FCERI mediated MAPK activation (Sus scrofa)
Activation of RAC1 by VAV (Sus scrofa)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
Activation of RAC1 by CRKII:DOCK180:ELMO (Sus scrofa)
GDP [cytosol]
Activation of RAC1 by VAV (Sus scrofa)
GDP [cytosol]
Metabolism (Sus scrofa)
Integration of energy metabolism (Sus scrofa)
Regulation of insulin secretion (Sus scrofa)
Adrenaline,noradrenaline inhibits insulin secretion (Sus scrofa)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Sus scrofa)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Sus scrofa)
RAP1A exchanges GDP for GTP (Sus scrofa)
GDP [cytosol]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
PCK1 phosphorylates OA to yield PEP (Sus scrofa)
GDP [cytosol]
Metabolism of nucleotides (Sus scrofa)
Nucleotide biosynthesis (Sus scrofa)
Purine ribonucleoside monophosphate biosynthesis (Sus scrofa)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Sus scrofa)
GDP [cytosol]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
Addition of a second mannose to the N-glycan precursor by ALG2 (Sus scrofa)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Sus scrofa)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Sus scrofa)
Synthesis of dolichyl-phosphate mannose (Sus scrofa)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Sus scrofa)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Sus scrofa)
ER to Golgi Anterograde Transport (Sus scrofa)
COPII-mediated vesicle transport (Sus scrofa)
Nucleotide exchange on RAB1 (Sus scrofa)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Sus scrofa)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Sus scrofa)
Synthesis of dolichyl-phosphate mannose (Sus scrofa)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Sus scrofa)
GDP [cytosol]
Translation (Sus scrofa)
Eukaryotic Translation Initiation (Sus scrofa)
Cap-dependent Translation Initiation (Sus scrofa)
Recycling of eIF2:GDP (Sus scrofa)
eIF2 activation (Sus scrofa)
GDP [cytosol]
Organelle biogenesis and maintenance (Sus scrofa)
Cilium Assembly (Sus scrofa)
Anchoring of the basal body to the plasma membrane (Sus scrofa)
RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Sus scrofa)
VxPx cargo-targeting to cilium (Sus scrofa)
GBF1 stimulates nucleotide exchange on ARF4 (Sus scrofa)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
GDP [cytosol]
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
p75 NTR receptor-mediated signalling (Sus scrofa)
Cell death signalling via NRAGE, NRIF and NADE (Sus scrofa)
NRAGE signals death through JNK (Sus scrofa)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Sus scrofa)
GDP [cytosol]
Integrin signaling (Sus scrofa)
Activation of Rap1 by cytosolic GEFs (Sus scrofa)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Sus scrofa)
GDP [cytosol]
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
Intrinsic nucleotide exchange on RAS (Sus scrofa)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
RAS processing (Sus scrofa)
mature p21 RAS binds GDP (Sus scrofa)
GDP [cytosol]
MTOR signalling (Sus scrofa)
GTP loading by Rheb (Sus scrofa)
GDP [cytosol]
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (12/13) signalling events (Sus scrofa)
GEFs activate RhoA,B,C (Sus scrofa)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Sus scrofa)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Sus scrofa)
GDP [cytosol]
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
GDP [cytosol]
Opioid Signalling (Sus scrofa)
G-protein activation (Sus scrofa)
G-protein alpha subunit is inactivated (Sus scrofa)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Sus scrofa)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Sus scrofa)
GDP [cytosol]
G alpha (q) signalling events (Sus scrofa)
Gastrin-CREB signalling pathway via PKC and MAPK (Sus scrofa)
EGFR Transactivation by Gastrin (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Sus scrofa)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
GDP [cytosol]
G alpha (s) signalling events (Sus scrofa)
GPER1 signaling (Sus scrofa)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Sus scrofa)
GDP [cytosol]
Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
GDP [cytosol]
G alpha (z) signalling events (Sus scrofa)
Liganded Gz-activating GPCR acts as a GEF for Gz (Sus scrofa)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Sus scrofa)
Activation of RAC1 by the PXN:CRK complex (Sus scrofa)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by EGFR (Sus scrofa)
GRB2 events in EGFR signaling (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Sus scrofa)
GDP [cytosol]
SHC1 events in EGFR signaling (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Sus scrofa)
GDP [cytosol]
Signaling by ERBB2 (Sus scrofa)
GRB2 events in ERBB2 signaling (Sus scrofa)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)
GDP [cytosol]
Signaling by ERBB4 (Sus scrofa)
SHC1 events in ERBB4 signaling (Sus scrofa)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Sus scrofa)
GDP [cytosol]
Signaling by FGFR (Sus scrofa)
Signaling by FGFR1 (Sus scrofa)
Downstream signaling of activated FGFR1 (Sus scrofa)
FRS-mediated FGFR1 signaling (Sus scrofa)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Signaling by FGFR2 (Sus scrofa)
Downstream signaling of activated FGFR2 (Sus scrofa)
FRS-mediated FGFR2 signaling (Sus scrofa)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Sus scrofa)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Signaling by FGFR3 (Sus scrofa)
Downstream signaling of activated FGFR3 (Sus scrofa)
FRS-mediated FGFR3 signaling (Sus scrofa)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Sus scrofa)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Signaling by FGFR4 (Sus scrofa)
Downstream signaling of activated FGFR4 (Sus scrofa)
FRS-mediated FGFR4 signaling (Sus scrofa)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Sus scrofa)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
GDP [cytosol]
Signaling by MET (Sus scrofa)
MET activates RAS signaling (Sus scrofa)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Sus scrofa)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Sus scrofa)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Sus scrofa)
GDP [cytosol]
MET promotes cell motility (Sus scrofa)
MET activates RAP1 and RAC1 (Sus scrofa)
DOCK7 activates RAC1 (Sus scrofa)
GDP [cytosol]
RAPGEF1 activates RAP1 (Sus scrofa)
GDP [cytosol]
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
Signalling to ERKs (Sus scrofa)
Prolonged ERK activation events (Sus scrofa)
ARMS-mediated activation (Sus scrofa)
C3G stimulates nucleotide exchange on Rap1 (Sus scrofa)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Sus scrofa)
Activated NTRK2 signals through FYN (Sus scrofa)
NTRK2 activates RAC1 (Sus scrofa)
DOCK3 activates RAC1 (Sus scrofa)
GDP [cytosol]
Signaling by PDGF (Sus scrofa)
Downstream signal transduction (Sus scrofa)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)
GDP [cytosol]
Signaling by SCF-KIT (Sus scrofa)
Activation of RAC1 (Sus scrofa)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Sus scrofa)
GDP [cytosol]
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Sus scrofa)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase cycle (Sus scrofa)
CDC42 GTPase cycle (Sus scrofa)
CDC42 GEFs activate CDC42 (Sus scrofa)
GDP [cytosol]
RAC1 GTPase cycle (Sus scrofa)
RAC1 GEFs activate RAC1 (Sus scrofa)
GDP [cytosol]
RAC2 GTPase cycle (Sus scrofa)
RAC2 GEFs activate RAC2 (Sus scrofa)
GDP [cytosol]
RAC3 GTPase cycle (Sus scrofa)
RAC3 GEFs activate RAC3 (Sus scrofa)
GDP [cytosol]
RHOA GTPase cycle (Sus scrofa)
RHOA GEFs activate RHOA (Sus scrofa)
GDP [cytosol]
RHOB GTPase cycle (Sus scrofa)
RHOB GEFs activate RHOB (Sus scrofa)
GDP [cytosol]
RHOC GTPase cycle (Sus scrofa)
RHOC GEFs activate RHOC (Sus scrofa)
GDP [cytosol]
RHOD GTPase cycle (Sus scrofa)
RHOD auto-activates (Sus scrofa)
GDP [cytosol]
RHOF GTPase cycle (Sus scrofa)
RHOF auto-activates (Sus scrofa)
GDP [cytosol]
RHOG GTPase cycle (Sus scrofa)
RHOG GEFs activate RHOG (Sus scrofa)
GDP [cytosol]
RHOJ GTPase cycle (Sus scrofa)
RHOJ GEFs activate RHOJ (Sus scrofa)
GDP [cytosol]
RHOQ GTPase cycle (Sus scrofa)
RHOQ GEFs activate RHOQ (Sus scrofa)
GDP [cytosol]
RHOU GTPase cycle (Sus scrofa)
RHOU auto-activates (Sus scrofa)
GDP [cytosol]
RHOV GTPase cycle (Sus scrofa)
RHOV binds GTP (Sus scrofa)
GDP [cytosol]
Signaling by WNT (Sus scrofa)
Beta-catenin independent WNT signaling (Sus scrofa)
Ca2+ pathway (Sus scrofa)
WNT:FZD complex promotes G-protein nucleotide exchange (Sus scrofa)
GDP [cytosol]
Transport of small molecules (Sus scrofa)
Aquaporin-mediated transport (Sus scrofa)
Vasopressin regulates renal water homeostasis via Aquaporins (Sus scrofa)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Sus scrofa)
GDP [cytosol]
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
ER to Golgi Anterograde Transport (Sus scrofa)
COPII-mediated vesicle transport (Sus scrofa)
Nucleotide exchange on RAB1 (Sus scrofa)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Sus scrofa)
GDP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Sus scrofa)
Golgi-to-ER retrograde transport (Sus scrofa)
COPI-independent Golgi-to-ER retrograde traffic (Sus scrofa)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Sus scrofa)
GDP [cytosol]
Rab regulation of trafficking (Sus scrofa)
RAB GEFs exchange GTP for GDP on RABs (Sus scrofa)
DENND1s exchange GTP for GDP on RAB35 (Sus scrofa)
GDP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Sus scrofa)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Sus scrofa)
GDP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Sus scrofa)
GDP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Sus scrofa)
GDP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Sus scrofa)
GDP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Sus scrofa)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Sus scrofa)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Sus scrofa)
GDP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Sus scrofa)
GDP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Sus scrofa)
GDP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Sus scrofa)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Sus scrofa)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Sus scrofa)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Sus scrofa)
Golgi Associated Vesicle Biogenesis (Sus scrofa)
trans-Golgi Network Vesicle Scission (Sus scrofa)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Sus scrofa)
trans-Golgi Network Lysosomal Vesicle Scission (Sus scrofa)
GDP [cytosol]
trans-Golgi Network Coat Activation (Sus scrofa)
GDP [cytosol]
Cell Cycle (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Metaphase and Anaphase (Xenopus tropicalis)
Mitotic Anaphase (Xenopus tropicalis)
Nuclear Envelope (NE) Reassembly (Xenopus tropicalis)
Postmitotic nuclear pore complex (NPC) reformation (Xenopus tropicalis)
RCC1 stimulates GDP to GTP exchange on RAN (Xenopus tropicalis)
GDP [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to starvation (Xenopus tropicalis)
Amino acids regulate mTORC1 (Xenopus tropicalis)
RRAGA,B exchanges GDP for GTP (Xenopus tropicalis)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Xenopus tropicalis)
GDP [cytosol]
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
EPH-Ephrin signaling (Xenopus tropicalis)
EPH-ephrin mediated repulsion of cells (Xenopus tropicalis)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
GDP [cytosol]
EPHA-mediated growth cone collapse (Xenopus tropicalis)
NGEF exchanges GTP for GDP on RHOA (Xenopus tropicalis)
GDP [cytosol]
EPHB-mediated forward signaling (Xenopus tropicalis)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Xenopus tropicalis)
GDP [cytosol]
NCAM signaling for neurite out-growth (Xenopus tropicalis)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Xenopus tropicalis)
GDP [cytosol]
Netrin-1 signaling (Xenopus tropicalis)
DCC mediated attractive signaling (Xenopus tropicalis)
Activation of Cdc42 (Xenopus tropicalis)
GDP [cytosol]
Activation of Rac1 (Xenopus tropicalis)
GDP [cytosol]
Semaphorin interactions (Xenopus tropicalis)
Sema4D in semaphorin signaling (Xenopus tropicalis)
Sema4D induced cell migration and growth-cone collapse (Xenopus tropicalis)
Activation of Rho by LARG and PDZ-RhoGEF (Xenopus tropicalis)
GDP [cytosol]
Drug ADME (Xenopus tropicalis)
Azathioprine ADME (Xenopus tropicalis)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Xenopus tropicalis)
GDP [cytosol]
Hemostasis (Xenopus tropicalis)
Cell surface interactions at the vascular wall (Xenopus tropicalis)
Tie2 Signaling (Xenopus tropicalis)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Xenopus tropicalis)
GDP [cytosol]
Platelet activation, signaling and aggregation (Xenopus tropicalis)
GPVI-mediated activation cascade (Xenopus tropicalis)
VAV1 is a GEF for Rho/Rac family GTPases (Xenopus tropicalis)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Xenopus tropicalis)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Xenopus tropicalis)
Integrin signaling (Xenopus tropicalis)
Activation of Rap1 by cytosolic GEFs (Xenopus tropicalis)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Xenopus tropicalis)
GDP [cytosol]
Signal amplification (Xenopus tropicalis)
ADP signalling through P2Y purinoceptor 12 (Xenopus tropicalis)
Gi activation by P2Y purinoceptor 12 (Xenopus tropicalis)
GDP [cytosol]
Thromboxane signalling through TP receptor (Xenopus tropicalis)
G13 activation by TP receptor (Xenopus tropicalis)
GDP [cytosol]
Gq activation by TP receptor (Xenopus tropicalis)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Xenopus tropicalis)
Thrombin-activated PARs activate G12/13 (Xenopus tropicalis)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Xenopus tropicalis)
GDP [cytosol]
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Costimulation by the CD28 family (Xenopus tropicalis)
CD28 co-stimulation (Xenopus tropicalis)
CD28 dependent Vav1 pathway (Xenopus tropicalis)
Activation of Cdc42 by pVav1 (Xenopus tropicalis)
GDP [cytosol]
Activation of Rac1 by pVav1 (Xenopus tropicalis)
GDP [cytosol]
MHC class II antigen presentation (Xenopus tropicalis)
Translocation of TGN-lysosome vesicle to lysosome (Xenopus tropicalis)
GDP [cytosol]
Rap1 signalling (Xenopus tropicalis)
Activation of Rap1 by cytosolic GEFs (Xenopus tropicalis)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Xenopus tropicalis)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Xenopus tropicalis)
Downstream signaling events of B Cell Receptor (BCR) (Xenopus tropicalis)
Activation of RAS in B cells (Xenopus tropicalis)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Xenopus tropicalis)
GDP [cytosol]
Cytokine Signaling in Immune system (Xenopus tropicalis)
FLT3 Signaling (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Xenopus tropicalis)
GDP [cytosol]
Innate Immune System (Xenopus tropicalis)
DAP12 interactions (Xenopus tropicalis)
DAP12 signaling (Xenopus tropicalis)
Activation of RAC1 by VAV2/3 (Xenopus tropicalis)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Xenopus tropicalis)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
FCERI mediated MAPK activation (Xenopus tropicalis)
Activation of RAC1 by VAV (Xenopus tropicalis)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Xenopus tropicalis)
GDP [cytosol]
Metabolism (Xenopus tropicalis)
Integration of energy metabolism (Xenopus tropicalis)
Regulation of insulin secretion (Xenopus tropicalis)
Adrenaline,noradrenaline inhibits insulin secretion (Xenopus tropicalis)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Xenopus tropicalis)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Xenopus tropicalis)
RAP1A exchanges GDP for GTP (Xenopus tropicalis)
GDP [cytosol]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
PCK1 phosphorylates OA to yield PEP (Xenopus tropicalis)
GDP [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide biosynthesis (Xenopus tropicalis)
Purine ribonucleoside monophosphate biosynthesis (Xenopus tropicalis)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Xenopus tropicalis)
GDP [cytosol]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
Addition of a second mannose to the N-glycan precursor by ALG2 (Xenopus tropicalis)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Xenopus tropicalis)
Synthesis of dolichyl-phosphate mannose (Xenopus tropicalis)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Xenopus tropicalis)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Xenopus tropicalis)
ER to Golgi Anterograde Transport (Xenopus tropicalis)
COPII-mediated vesicle transport (Xenopus tropicalis)
Nucleotide exchange on RAB1 (Xenopus tropicalis)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Xenopus tropicalis)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Xenopus tropicalis)
Synthesis of dolichyl-phosphate mannose (Xenopus tropicalis)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Xenopus tropicalis)
GDP [cytosol]
Organelle biogenesis and maintenance (Xenopus tropicalis)
Cilium Assembly (Xenopus tropicalis)
Anchoring of the basal body to the plasma membrane (Xenopus tropicalis)
RAB3IP stimulates nucleotide exchange on RAB8A (Xenopus tropicalis)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Xenopus tropicalis)
VxPx cargo-targeting to cilium (Xenopus tropicalis)
RAB3IP stimulates nucleotide exchange on RAB8A (Xenopus tropicalis)
GDP [cytosol]
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
p75 NTR receptor-mediated signalling (Xenopus tropicalis)
Cell death signalling via NRAGE, NRIF and NADE (Xenopus tropicalis)
NRAGE signals death through JNK (Xenopus tropicalis)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Xenopus tropicalis)
GDP [cytosol]
Integrin signaling (Xenopus tropicalis)
Activation of Rap1 by cytosolic GEFs (Xenopus tropicalis)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Xenopus tropicalis)
GDP [cytosol]
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
Intrinsic nucleotide exchange on RAS (Xenopus tropicalis)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
MTOR signalling (Xenopus tropicalis)
GTP loading by Rheb (Xenopus tropicalis)
GDP [cytosol]
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (12/13) signalling events (Xenopus tropicalis)
GEFs activate RhoA,B,C (Xenopus tropicalis)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Xenopus tropicalis)
GDP [cytosol]
G alpha (i) signalling events (Xenopus tropicalis)
Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
GDP [cytosol]
Opioid Signalling (Xenopus tropicalis)
G-protein activation (Xenopus tropicalis)
G-protein alpha subunit is inactivated (Xenopus tropicalis)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Xenopus tropicalis)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Xenopus tropicalis)
GDP [cytosol]
G alpha (q) signalling events (Xenopus tropicalis)
Gastrin-CREB signalling pathway via PKC and MAPK (Xenopus tropicalis)
EGFR Transactivation by Gastrin (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Xenopus tropicalis)
GDP [cytosol]
G alpha (s) signalling events (Xenopus tropicalis)
GPER1 signaling (Xenopus tropicalis)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Xenopus tropicalis)
GDP [cytosol]
Liganded Gs-activating GPCR acts as a GEF for Gs (Xenopus tropicalis)
GDP [cytosol]
G alpha (z) signalling events (Xenopus tropicalis)
Liganded Gz-activating GPCR acts as a GEF for Gz (Xenopus tropicalis)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by PTK6 (Xenopus tropicalis)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Xenopus tropicalis)
Activation of RAC1 by the PXN:CRK complex (Xenopus tropicalis)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by EGFR (Xenopus tropicalis)
GRB2 events in EGFR signaling (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Xenopus tropicalis)
GDP [cytosol]
SHC1 events in EGFR signaling (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Xenopus tropicalis)
GDP [cytosol]
Signaling by ERBB2 (Xenopus tropicalis)
GRB2 events in ERBB2 signaling (Xenopus tropicalis)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Xenopus tropicalis)
GDP [cytosol]
Signaling by ERBB4 (Xenopus tropicalis)
SHC1 events in ERBB4 signaling (Xenopus tropicalis)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Xenopus tropicalis)
GDP [cytosol]
Signaling by FGFR (Xenopus tropicalis)
Signaling by FGFR1 (Xenopus tropicalis)
Downstream signaling of activated FGFR1 (Xenopus tropicalis)
FRS-mediated FGFR1 signaling (Xenopus tropicalis)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Xenopus tropicalis)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Signaling by FGFR2 (Xenopus tropicalis)
Downstream signaling of activated FGFR2 (Xenopus tropicalis)
FRS-mediated FGFR2 signaling (Xenopus tropicalis)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Xenopus tropicalis)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Signaling by FGFR3 (Xenopus tropicalis)
Downstream signaling of activated FGFR3 (Xenopus tropicalis)
FRS-mediated FGFR3 signaling (Xenopus tropicalis)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Xenopus tropicalis)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Signaling by FGFR4 (Xenopus tropicalis)
Downstream signaling of activated FGFR4 (Xenopus tropicalis)
FRS-mediated FGFR4 signaling (Xenopus tropicalis)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Xenopus tropicalis)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Signaling by MET (Xenopus tropicalis)
MET activates RAS signaling (Xenopus tropicalis)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Xenopus tropicalis)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Xenopus tropicalis)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Xenopus tropicalis)
GDP [cytosol]
MET promotes cell motility (Xenopus tropicalis)
MET activates RAP1 and RAC1 (Xenopus tropicalis)
DOCK7 activates RAC1 (Xenopus tropicalis)
GDP [cytosol]
RAPGEF1 activates RAP1 (Xenopus tropicalis)
GDP [cytosol]
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
Signalling to ERKs (Xenopus tropicalis)
Prolonged ERK activation events (Xenopus tropicalis)
ARMS-mediated activation (Xenopus tropicalis)
C3G stimulates nucleotide exchange on Rap1 (Xenopus tropicalis)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Xenopus tropicalis)
Activated NTRK2 signals through FYN (Xenopus tropicalis)
NTRK2 activates RAC1 (Xenopus tropicalis)
DOCK3 activates RAC1 (Xenopus tropicalis)
GDP [cytosol]
Signaling by PDGF (Xenopus tropicalis)
Downstream signal transduction (Xenopus tropicalis)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Xenopus tropicalis)
GDP [cytosol]
Signaling by SCF-KIT (Xenopus tropicalis)
Activation of RAC1 (Xenopus tropicalis)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Xenopus tropicalis)
GDP [cytosol]
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
CDC42 GTPase cycle (Xenopus tropicalis)
CDC42 GEFs activate CDC42 (Xenopus tropicalis)
GDP [cytosol]
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 GEFs activate RAC1 (Xenopus tropicalis)
GDP [cytosol]
RAC2 GTPase cycle (Xenopus tropicalis)
RAC2 GEFs activate RAC2 (Xenopus tropicalis)
GDP [cytosol]
RAC3 GTPase cycle (Xenopus tropicalis)
RAC3 GEFs activate RAC3 (Xenopus tropicalis)
GDP [cytosol]
RHOA GTPase cycle (Xenopus tropicalis)
RHOA GEFs activate RHOA (Xenopus tropicalis)
GDP [cytosol]
RHOB GTPase cycle (Xenopus tropicalis)
RHOB GEFs activate RHOB (Xenopus tropicalis)
GDP [cytosol]
RHOD GTPase cycle (Xenopus tropicalis)
RHOD auto-activates (Xenopus tropicalis)
GDP [cytosol]
RHOF GTPase cycle (Xenopus tropicalis)
RHOF auto-activates (Xenopus tropicalis)
GDP [cytosol]
RHOG GTPase cycle (Xenopus tropicalis)
RHOG GEFs activate RHOG (Xenopus tropicalis)
GDP [cytosol]
RHOJ GTPase cycle (Xenopus tropicalis)
RHOJ GEFs activate RHOJ (Xenopus tropicalis)
GDP [cytosol]
RHOQ GTPase cycle (Xenopus tropicalis)
RHOQ GEFs activate RHOQ (Xenopus tropicalis)
GDP [cytosol]
RHOU GTPase cycle (Xenopus tropicalis)
RHOU auto-activates (Xenopus tropicalis)
GDP [cytosol]
RHOV GTPase cycle (Xenopus tropicalis)
RHOV binds GTP (Xenopus tropicalis)
GDP [cytosol]
Signaling by WNT (Xenopus tropicalis)
Beta-catenin independent WNT signaling (Xenopus tropicalis)
Ca2+ pathway (Xenopus tropicalis)
WNT:FZD complex promotes G-protein nucleotide exchange (Xenopus tropicalis)
GDP [cytosol]
Transport of small molecules (Xenopus tropicalis)
Aquaporin-mediated transport (Xenopus tropicalis)
Vasopressin regulates renal water homeostasis via Aquaporins (Xenopus tropicalis)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Xenopus tropicalis)
GDP [cytosol]
Vesicle-mediated transport (Xenopus tropicalis)
Membrane Trafficking (Xenopus tropicalis)
ER to Golgi Anterograde Transport (Xenopus tropicalis)
COPII-mediated vesicle transport (Xenopus tropicalis)
Nucleotide exchange on RAB1 (Xenopus tropicalis)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Xenopus tropicalis)
GDP [cytosol]
Rab regulation of trafficking (Xenopus tropicalis)
RAB GEFs exchange GTP for GDP on RABs (Xenopus tropicalis)
DENND1s exchange GTP for GDP on RAB35 (Xenopus tropicalis)
GDP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Xenopus tropicalis)
GDP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Xenopus tropicalis)
GDP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Xenopus tropicalis)
GDP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Xenopus tropicalis)
GDP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Xenopus tropicalis)
GDP [cytosol]
trans-Golgi Network Vesicle Budding (Xenopus tropicalis)
Golgi Associated Vesicle Biogenesis (Xenopus tropicalis)
trans-Golgi Network Vesicle Scission (Xenopus tropicalis)
GDP [cytosol]
Lysosome Vesicle Biogenesis (Xenopus tropicalis)
trans-Golgi Network Lysosomal Vesicle Scission (Xenopus tropicalis)
GDP [cytosol]
External Reference Information
External Reference
GDP(3-) [ChEBI:58189]
Participates
as a component of
DRheb-GDP complex [plasma membrane] (Drosophila melanogaster)
GEF:DRheb-GDP complex [plasma membrane] (Drosophila melanogaster)
RHO1:GDP [cytosol] (Drosophila melanogaster)
RHO1:GDP [plasma membrane] (Drosophila melanogaster)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
DNM:GDP [cytosol] (Mus musculus)
DNM:GDP [cytosol] (Drosophila melanogaster)
DNM:GDP [cytosol] (Gallus gallus)
DNM:GDP [cytosol] (Canis familiaris)
DNM:GDP [cytosol] (Rattus norvegicus)
DNM:GDP [cytosol] (Sus scrofa)
DNM:GDP [cytosol] (Caenorhabditis elegans)
DNM:GDP [cytosol] (Schizosaccharomyces pombe)
DNM:GDP [cytosol] (Bos taurus)
DNM:GDP [cytosol] (Homo sapiens)
GGC-Rab14:GDP [cytoplasmic vesicle membrane] (Mus musculus)
GGC-Rab8a:GDP [cytoplasmic vesicle membrane] (Mus musculus)
GGC-Rab10:GDP [cytoplasmic vesicle membrane] (Mus musculus)
GGC-Rab13:GDP [cytoplasmic vesicle membrane] (Mus musculus)
GGC-Rab13:GDP [cytoplasmic vesicle membrane] (Rattus norvegicus)
GGC-Rab8a:GDP [cytoplasmic vesicle membrane] (Rattus norvegicus)
GGC-Rab14:GDP [cytoplasmic vesicle membrane] (Rattus norvegicus)
GGC-RAB8A:GDP [cytoplasmic vesicle membrane] (Homo sapiens)
GGC-RAB10:GDP [cytoplasmic vesicle membrane] (Homo sapiens)
GGC-RAB14:GDP [cytoplasmic vesicle membrane] (Homo sapiens)
GGC-RAB13:GDP [cytoplasmic vesicle membrane] (Homo sapiens)
Arf1-GDP [Golgi membrane] (Drosophila melanogaster)
Arf1-GDP [Golgi membrane] (Gallus gallus)
Arf1-GDP [Golgi membrane] (Bos taurus)
Arf1-GDP [Golgi membrane] (Canis familiaris)
Arf1-GDP [Golgi membrane] (Xenopus tropicalis)
Arf1-GDP [Golgi membrane] (Mus musculus)
Arf1-GDP [Golgi membrane] (Saccharomyces cerevisiae)
Arf1-GDP [Golgi membrane] (Rattus norvegicus)
Arf1-GDP [Golgi membrane] (Schizosaccharomyces pombe)
Arf1-GDP [Golgi membrane] (Dictyostelium discoideum)
Arf1-GDP [Golgi membrane] (Sus scrofa)
Arf1-GDP [Golgi membrane] (Homo sapiens)
RAB18:GDP [cytosol] (Gallus gallus)
RAB18:GDP [cytosol] (Danio rerio)
RAB18:GDP [cytosol] (Sus scrofa)
RAB18:GDP [cytosol] (Plasmodium falciparum)
RAB18:GDP [cytosol] (Drosophila melanogaster)
RAB18:GDP [cytosol] (Mus musculus)
RAB18:GDP [cytosol] (Bos taurus)
RAB18:GDP [cytosol] (Rattus norvegicus)
RAB18:GDP [cytosol] (Caenorhabditis elegans)
RAB18:GDP [cytosol] (Dictyostelium discoideum)
RAB18:GDP [cytosol] (Canis familiaris)
RAB18:GDP [cytosol] (Homo sapiens)
RAB43:GDP [trans-Golgi network membrane] (Rattus norvegicus)
RAB43:GDP [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB43:GDP [trans-Golgi network membrane] (Sus scrofa)
RAB43:GDP [trans-Golgi network membrane] (Mus musculus)
RAB43:GDP [trans-Golgi network membrane] (Plasmodium falciparum)
RAB43:GDP [trans-Golgi network membrane] (Gallus gallus)
RAB43:GDP [trans-Golgi network membrane] (Dictyostelium discoideum)
RAB43:GDP [trans-Golgi network membrane] (Drosophila melanogaster)
RAB43:GDP [trans-Golgi network membrane] (Schizosaccharomyces pombe)
RAB43:GDP [trans-Golgi network membrane] (Homo sapiens)
RAB9:GDP [cytosol] (Drosophila melanogaster)
RAB9:GDP [cytosol] (Sus scrofa)
RAB9:GDP [cytosol] (Dictyostelium discoideum)
RAB9:GDP [cytosol] (Gallus gallus)
RAB9:GDP [cytosol] (Rattus norvegicus)
RAB9:GDP [cytosol] (Mus musculus)
RAB9:GDP [cytosol] (Bos taurus)
RAB9:GDP [cytosol] (Canis familiaris)
RAB9:GDP [cytosol] (Homo sapiens)
RAB6:GDP [cytosol] (Gallus gallus)
RAB6:GDP [cytosol] (Schizosaccharomyces pombe)
RAB6:GDP [cytosol] (Saccharomyces cerevisiae)
RAB6:GDP [cytosol] (Plasmodium falciparum)
RAB6:GDP [cytosol] (Dictyostelium discoideum)
RAB6:GDP [cytosol] (Drosophila melanogaster)
RAB6:GDP [cytosol] (Mus musculus)
RAB6:GDP [cytosol] (Caenorhabditis elegans)
RAB6:GDP [cytosol] (Bos taurus)
RAB6:GDP [cytosol] (Rattus norvegicus)
RAB6:GDP [cytosol] (Homo sapiens)
RAB6:GDP [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB6:GDP [trans-Golgi network membrane] (Drosophila melanogaster)
RAB6:GDP [trans-Golgi network membrane] (Gallus gallus)
RAB6:GDP [trans-Golgi network membrane] (Schizosaccharomyces pombe)
RAB6:GDP [trans-Golgi network membrane] (Bos taurus)
RAB6:GDP [trans-Golgi network membrane] (Saccharomyces cerevisiae)
RAB6:GDP [trans-Golgi network membrane] (Mus musculus)
RAB6:GDP [trans-Golgi network membrane] (Dictyostelium discoideum)
RAB6:GDP [trans-Golgi network membrane] (Rattus norvegicus)
RAB6:GDP [trans-Golgi network membrane] (Homo sapiens)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Danio rerio)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Dictyostelium discoideum)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
RAB35:GDP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
RAB33:GDP [Golgi membrane] (Caenorhabditis elegans)
RAB33:GDP [Golgi membrane] (Bos taurus)
RAB33:GDP [Golgi membrane] (Sus scrofa)
RAB33:GDP [Golgi membrane] (Xenopus tropicalis)
RAB33:GDP [Golgi membrane] (Danio rerio)
RAB33:GDP [Golgi membrane] (Rattus norvegicus)
RAB33:GDP [Golgi membrane] (Canis familiaris)
RAB33:GDP [Golgi membrane] (Dictyostelium discoideum)
RAB33:GDP [Golgi membrane] (Gallus gallus)
RAB33:GDP [Golgi membrane] (Mus musculus)
RAB33:GDP [Golgi membrane] (Homo sapiens)
RAB7A:GDP [lysosomal membrane] (Sus scrofa)
RAB7A:GDP [lysosomal membrane] (Rattus norvegicus)
RAB7A:GDP [lysosomal membrane] (Saccharomyces cerevisiae)
RAB7A:GDP [lysosomal membrane] (Xenopus tropicalis)
RAB7A:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
RAB7A:GDP [lysosomal membrane] (Danio rerio)
RAB7A:GDP [lysosomal membrane] (Plasmodium falciparum)
RAB7A:GDP [lysosomal membrane] (Dictyostelium discoideum)
RAB7A:GDP [lysosomal membrane] (Canis familiaris)
RAB7A:GDP [lysosomal membrane] (Mus musculus)
RAB7A:GDP [lysosomal membrane] (Gallus gallus)
RAB7A:GDP [lysosomal membrane] (Bos taurus)
RAB7A:GDP [lysosomal membrane] (Caenorhabditis elegans)
RAB7A:GDP [lysosomal membrane] (Drosophila melanogaster)
RAB7A:GDP [lysosomal membrane] (Homo sapiens)
GGC-RAB5:GDP [cytosol] (Mus musculus)
GGC-RAB5:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB5:GDP [cytosol] (Danio rerio)
GGC-RAB5:GDP [cytosol] (Canis familiaris)
GGC-RAB5:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB5:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB5:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB5:GDP [cytosol] (Bos taurus)
GGC-RAB5:GDP [cytosol] (Sus scrofa)
GGC-RAB5:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB5:GDP [cytosol] (Gallus gallus)
GGC-RAB5:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB5:GDP [cytosol] (Rattus norvegicus)
GGC-RAB5:GDP [cytosol] (Homo sapiens)
GGC-RAB27A:GDP [cytosol] (Danio rerio)
GGC-RAB27A:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB27A:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB27A:GDP [cytosol] (Gallus gallus)
GGC-RAB27A:GDP [cytosol] (Mus musculus)
GGC-RAB27A:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB27A:GDP [cytosol] (Sus scrofa)
GGC-RAB27A:GDP [cytosol] (Rattus norvegicus)
GGC-RAB27A:GDP [cytosol] (Bos taurus)
GGC-RAB27A:GDP [cytosol] (Canis familiaris)
GGC-RAB27A:GDP [cytosol] (Homo sapiens)
GGC-RAB27B:GDP [cytosol] (Bos taurus)
GGC-RAB27B:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB27B:GDP [cytosol] (Rattus norvegicus)
GGC-RAB27B:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB27B:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB27B:GDP [cytosol] (Mus musculus)
GGC-RAB27B:GDP [cytosol] (Sus scrofa)
GGC-RAB27B:GDP [cytosol] (Homo sapiens)
GGC-RAB10:GDP [cytosol] (Mus musculus)
GGC-RAB10:GDP [cytosol] (Gallus gallus)
GGC-RAB10:GDP [cytosol] (Danio rerio)
GGC-RAB10:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB10:GDP [cytosol] (Rattus norvegicus)
GGC-RAB10:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB10:GDP [cytosol] (Sus scrofa)
GGC-RAB10:GDP [cytosol] (Bos taurus)
GGC-RAB10:GDP [cytosol] (Canis familiaris)
GGC-RAB10:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB10:GDP [cytosol] (Homo sapiens)
GGC-RAB8:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB8:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB8:GDP [cytosol] (Sus scrofa)
GGC-RAB8:GDP [cytosol] (Gallus gallus)
GGC-RAB8:GDP [cytosol] (Danio rerio)
GGC-RAB8:GDP [cytosol] (Rattus norvegicus)
GGC-RAB8:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB8:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB8:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB8:GDP [cytosol] (Bos taurus)
GGC-RAB8:GDP [cytosol] (Canis familiaris)
GGC-RAB8:GDP [cytosol] (Mus musculus)
GGC-RAB8:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB8:GDP [cytosol] (Homo sapiens)
GGC-RAB31:GDP [cytosol] (Bos taurus)
GGC-RAB31:GDP [cytosol] (Rattus norvegicus)
GGC-RAB31:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB31:GDP [cytosol] (Gallus gallus)
GGC-RAB31:GDP [cytosol] (Sus scrofa)
GGC-RAB31:GDP [cytosol] (Mus musculus)
GGC-RAB31:GDP [cytosol] (Homo sapiens)
GGC-RAB9:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB9:GDP [cytosol] (Mus musculus)
GGC-RAB9:GDP [cytosol] (Rattus norvegicus)
GGC-RAB9:GDP [cytosol] (Bos taurus)
GGC-RAB9:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB9:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB9:GDP [cytosol] (Canis familiaris)
GGC-RAB9:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB9:GDP [cytosol] (Gallus gallus)
GGC-RAB9:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB9:GDP [cytosol] (Danio rerio)
GGC-RAB9:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB9:GDP [cytosol] (Sus scrofa)
GGC-RAB9:GDP [cytosol] (Homo sapiens)
GGC-RAB39:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB39:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB39:GDP [cytosol] (Sus scrofa)
GGC-RAB39:GDP [cytosol] (Canis familiaris)
GGC-RAB39:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB39:GDP [cytosol] (Bos taurus)
GGC-RAB39:GDP [cytosol] (Rattus norvegicus)
GGC-RAB39:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB39:GDP [cytosol] (Mus musculus)
GGC-RAB39:GDP [cytosol] (Gallus gallus)
GGC-RAB39:GDP [cytosol] (Homo sapiens)
GGC-RAB3A:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB3A:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB3A:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB3A:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB3A:GDP [cytosol] (Mus musculus)
GGC-RAB3A:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB3A:GDP [cytosol] (Canis familiaris)
GGC-RAB3A:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB3A:GDP [cytosol] (Bos taurus)
GGC-RAB3A:GDP [cytosol] (Sus scrofa)
GGC-RAB3A:GDP [cytosol] (Gallus gallus)
GGC-RAB3A:GDP [cytosol] (Rattus norvegicus)
GGC-RAB3A:GDP [cytosol] (Danio rerio)
GGC-RAB3A:GDP [cytosol] (Homo sapiens)
GGC-RAB14:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB14:GDP [cytosol] (Bos taurus)
GGC-RAB14:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB14:GDP [cytosol] (Rattus norvegicus)
GGC-RAB14:GDP [cytosol] (Danio rerio)
GGC-RAB14:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB14:GDP [cytosol] (Mus musculus)
GGC-RAB14:GDP [cytosol] (Gallus gallus)
GGC-RAB14:GDP [cytosol] (Homo sapiens)
GGC-RAB7:GDP [cytosol] (Bos taurus)
GGC-RAB7:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB7:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB7:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB7:GDP [cytosol] (Rattus norvegicus)
GGC-RAB7:GDP [cytosol] (Mus musculus)
GGC-RAB7:GDP [cytosol] (Gallus gallus)
GGC-RAB7:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB7:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB7:GDP [cytosol] (Danio rerio)
GGC-RAB7:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB7:GDP [cytosol] (Canis familiaris)
GGC-RAB7:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB7:GDP [cytosol] (Sus scrofa)
GGC-RAB7:GDP [cytosol] (Homo sapiens)
GGC-RAB35:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB35:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB35:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB35:GDP [cytosol] (Canis familiaris)
GGC-RAB35:GDP [cytosol] (Gallus gallus)
GGC-RAB35:GDP [cytosol] (Mus musculus)
GGC-RAB35:GDP [cytosol] (Bos taurus)
GGC-RAB35:GDP [cytosol] (Rattus norvegicus)
GGC-RAB35:GDP [cytosol] (Danio rerio)
GGC-RAB35:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB35:GDP [cytosol] (Sus scrofa)
GGC-RAB35:GDP [cytosol] (Homo sapiens)
GGC-RAB18:GDP [cytosol] (Bos taurus)
GGC-RAB18:GDP [cytosol] (Mus musculus)
GGC-RAB18:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB18:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB18:GDP [cytosol] (Canis familiaris)
GGC-RAB18:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB18:GDP [cytosol] (Gallus gallus)
GGC-RAB18:GDP [cytosol] (Rattus norvegicus)
GGC-RAB18:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB18:GDP [cytosol] (Danio rerio)
GGC-RAB18:GDP [cytosol] (Sus scrofa)
GGC-RAB18:GDP [cytosol] (Homo sapiens)
RAB32,RAB38:GDP [cytosol] (Caenorhabditis elegans)
RAB32,RAB38:GDP [cytosol] (Saccharomyces cerevisiae)
RAB32,RAB38:GDP [cytosol] (Danio rerio)
RAB32,RAB38:GDP [cytosol] (Bos taurus)
RAB32,RAB38:GDP [cytosol] (Mus musculus)
RAB32,RAB38:GDP [cytosol] (Drosophila melanogaster)
RAB32,RAB38:GDP [cytosol] (Gallus gallus)
RAB32,RAB38:GDP [cytosol] (Dictyostelium discoideum)
RAB32,RAB38:GDP [cytosol] (Canis familiaris)
RAB32,RAB38:GDP [cytosol] (Sus scrofa)
RAB32,RAB38:GDP [cytosol] (Rattus norvegicus)
RAB32,RAB38:GDP [cytosol] (Homo sapiens)
GGC-RAB6:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB6:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB6:GDP [cytosol] (Mus musculus)
GGC-RAB6:GDP [cytosol] (Rattus norvegicus)
GGC-RAB6:GDP [cytosol] (Gallus gallus)
GGC-RAB6:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB6:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB6:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB6:GDP [cytosol] (Bos taurus)
GGC-RAB6:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB6:GDP [cytosol] (Homo sapiens)
GGC-RAB1A:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB1A:GDP [cytosol] (Danio rerio)
GGC-RAB1A:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB1A:GDP [cytosol] (Bos taurus)
GGC-RAB1A:GDP [cytosol] (Canis familiaris)
GGC-RAB1A:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB1A:GDP [cytosol] (Rattus norvegicus)
GGC-RAB1A:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB1A:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB1A:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB1A:GDP [cytosol] (Mus musculus)
GGC-RAB1A:GDP [cytosol] (Homo sapiens)
GGC-RAB1B:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB1B:GDP [cytosol] (Bos taurus)
GGC-RAB1B:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB1B:GDP [cytosol] (Danio rerio)
GGC-RAB1B:GDP [cytosol] (Rattus norvegicus)
GGC-RAB1B:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB1B:GDP [cytosol] (Plasmodium falciparum)
GGC-RAB1B:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB1B:GDP [cytosol] (Canis familiaris)
GGC-RAB1B:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB1B:GDP [cytosol] (Mus musculus)
GGC-RAB1B:GDP [cytosol] (Homo sapiens)
GGC-RAB21:GDP [cytosol] (Danio rerio)
GGC-RAB21:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB21:GDP [cytosol] (Mus musculus)
GGC-RAB21:GDP [cytosol] (Gallus gallus)
GGC-RAB21:GDP [cytosol] (Bos taurus)
GGC-RAB21:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB21:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB21:GDP [cytosol] (Rattus norvegicus)
GGC-RAB21:GDP [cytosol] (Homo sapiens)
GGC-RAB12:GDP [cytosol] (Sus scrofa)
GGC-RAB12:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB12:GDP [cytosol] (Gallus gallus)
GGC-RAB12:GDP [cytosol] (Canis familiaris)
GGC-RAB12:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB12:GDP [cytosol] (Danio rerio)
GGC-RAB12:GDP [cytosol] (Rattus norvegicus)
GGC-RAB12:GDP [cytosol] (Mus musculus)
GGC-RAB12:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB12:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB12:GDP [cytosol] (Bos taurus)
GGC-RAB12:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB12:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB12:GDP [cytosol] (Homo sapiens)
GGC-RAB13:GDP [cytosol] (Mus musculus)
GGC-RAB13:GDP [cytosol] (Xenopus tropicalis)
GGC-RAB13:GDP [cytosol] (Danio rerio)
GGC-RAB13:GDP [cytosol] (Rattus norvegicus)
GGC-RAB13:GDP [cytosol] (Dictyostelium discoideum)
GGC-RAB13:GDP [cytosol] (Caenorhabditis elegans)
GGC-RAB13:GDP [cytosol] (Drosophila melanogaster)
GGC-RAB13:GDP [cytosol] (Bos taurus)
GGC-RAB13:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RAB13:GDP [cytosol] (Canis familiaris)
GGC-RAB13:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RAB13:GDP [cytosol] (Sus scrofa)
GGC-RAB13:GDP [cytosol] (Homo sapiens)
RHOT1:GDP [mitochondrial outer membrane] (Mus musculus)
RHOT1:GDP [mitochondrial outer membrane] (Canis familiaris)
RHOT1:GDP [mitochondrial outer membrane] (Gallus gallus)
RHOT1:GDP [mitochondrial outer membrane] (Sus scrofa)
RHOT1:GDP [mitochondrial outer membrane] (Bos taurus)
RHOT1:GDP [mitochondrial outer membrane] (Danio rerio)
RHOT1:GDP [mitochondrial outer membrane] (Homo sapiens)
Miro:GDP [mitochondrial outer membrane] (Drosophila melanogaster)
RHOT2:GDP [mitochondrial outer membrane] (Mus musculus)
RHOT2:GDP [mitochondrial outer membrane] (Rattus norvegicus)
RHOT1:GDP [mitochondrial outer membrane] (Dictyostelium discoideum)
RHOT1:GDP [mitochondrial outer membrane] (Caenorhabditis elegans)
RHOT1:GDP [mitochondrial outer membrane] (Saccharomyces cerevisiae)
RHOT1:GDP [mitochondrial outer membrane] (Schizosaccharomyces pombe)
RHOT2:GDP [mitochondrial outer membrane] (Gallus gallus)
RHOT2:GDP [mitochondrial outer membrane] (Xenopus tropicalis)
RHOT2:GDP [mitochondrial outer membrane] (Danio rerio)
RHOT2:GDP [mitochondrial outer membrane] (Bos taurus)
RHOT1:GDP [mitochondrial outer membrane] (Drosophila melanogaster)
RHOT2:GDP [mitochondrial outer membrane] (Sus scrofa)
RHOT2:GDP [mitochondrial outer membrane] (Homo sapiens)
RHOA:GDP [cytosol] (Canis familiaris)
RHOA:GDP [cytosol] (Sus scrofa)
RHOA:GDP [cytosol] (Drosophila melanogaster)
RHOA:GDP [cytosol] (Xenopus tropicalis)
RHOA:GDP [cytosol] (Caenorhabditis elegans)
RHOA:GDP [cytosol] (Danio rerio)
RHOA:GDP [cytosol] (Bos taurus)
RHOA:GDP [cytosol] (Rattus norvegicus)
RHOA:GDP [cytosol] (Gallus gallus)
RHOA:GDP [cytosol] (Mus musculus)
RHOA:GDP [cytosol] (Homo sapiens)
RHOC:GDP [cytosol] (Schizosaccharomyces pombe)
RHOC:GDP [cytosol] (Bos taurus)
RHOC:GDP [cytosol] (Mus musculus)
RHOC:GDP [cytosol] (Saccharomyces cerevisiae)
RHOC:GDP [cytosol] (Sus scrofa)
RHOC:GDP [cytosol] (Gallus gallus)
RHOC:GDP [cytosol] (Canis familiaris)
RHOC:GDP [cytosol] (Homo sapiens)
RHOC:GDP [plasma membrane] (Bos taurus)
RHOC:GDP [plasma membrane] (Gallus gallus)
RHOC:GDP [plasma membrane] (Canis familiaris)
RHOC:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOC:GDP [plasma membrane] (Sus scrofa)
RHOC:GDP [plasma membrane] (Mus musculus)
RHOC:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOC:GDP [plasma membrane] (Homo sapiens)
RHOV:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOV:GDP [plasma membrane] (Xenopus tropicalis)
RHOV:GDP [plasma membrane] (Canis familiaris)
RHOV:GDP [plasma membrane] (Danio rerio)
RHOV:GDP [plasma membrane] (Rattus norvegicus)
RHOV:GDP [plasma membrane] (Dictyostelium discoideum)
RHOV:GDP [plasma membrane] (Sus scrofa)
RHOV:GDP [plasma membrane] (Caenorhabditis elegans)
RHOV:GDP [plasma membrane] (Bos taurus)
RHOV:GDP [plasma membrane] (Drosophila melanogaster)
RHOV:GDP [plasma membrane] (Mus musculus)
RHOV:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOV:GDP [plasma membrane] (Gallus gallus)
RHOV:GDP [plasma membrane] (Homo sapiens)
CDC42:GDP [plasma membrane] (Rattus norvegicus)
CDC42:GDP [plasma membrane] (Xenopus tropicalis)
CDC42:GDP [plasma membrane] (Schizosaccharomyces pombe)
CDC42:GDP [plasma membrane] (Bos taurus)
CDC42:GDP [plasma membrane] (Canis familiaris)
CDC42:GDP [plasma membrane] (Sus scrofa)
CDC42:GDP [plasma membrane] (Gallus gallus)
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
CDC42:GDP [plasma membrane] (Caenorhabditis elegans)
CDC42:GDP [plasma membrane] (Danio rerio)
CDC42:GDP [plasma membrane] (Drosophila melanogaster)
CDC42:GDP [plasma membrane] (Saccharomyces cerevisiae)
CDC42:GDP [plasma membrane] (Homo sapiens)
RAC2:GDP [cytosol] (Gallus gallus)
RAC2:GDP [cytosol] (Danio rerio)
RAC2:GDP [cytosol] (Bos taurus)
RAC2:GDP [cytosol] (Canis familiaris)
RAC2:GDP [cytosol] (Mus musculus)
RAC2:GDP [cytosol] (Caenorhabditis elegans)
RAC2:GDP [cytosol] (Drosophila melanogaster)
RAC2:GDP [cytosol] (Sus scrofa)
RAC2:GDP [cytosol] (Dictyostelium discoideum)
RAC2:GDP [cytosol] (Rattus norvegicus)
RAC2:GDP [cytosol] (Xenopus tropicalis)
RAC2:GDP [cytosol] (Homo sapiens)
RAC2:GDP [plasma membrane] (Rattus norvegicus)
RAC2:GDP [plasma membrane] (Xenopus tropicalis)
RAC2:GDP [plasma membrane] (Canis familiaris)
RAC2:GDP [plasma membrane] (Gallus gallus)
RAC2:GDP [plasma membrane] (Drosophila melanogaster)
RAC2:GDP [plasma membrane] (Mus musculus)
RAC2:GDP [plasma membrane] (Caenorhabditis elegans)
RAC2:GDP [plasma membrane] (Sus scrofa)
RAC2:GDP [plasma membrane] (Bos taurus)
RAC2:GDP [plasma membrane] (Dictyostelium discoideum)
RAC2:GDP [plasma membrane] (Danio rerio)
RAC2:GDP [plasma membrane] (Homo sapiens)
RHOD:GDP [cytosol] (Danio rerio)
RHOD:GDP [cytosol] (Mus musculus)
RHOD:GDP [cytosol] (Sus scrofa)
RHOD:GDP [cytosol] (Bos taurus)
RHOD:GDP [cytosol] (Canis familiaris)
RHOD:GDP [cytosol] (Caenorhabditis elegans)
RHOD:GDP [cytosol] (Saccharomyces cerevisiae)
RHOD:GDP [cytosol] (Drosophila melanogaster)
RHOD:GDP [cytosol] (Xenopus tropicalis)
RHOD:GDP [cytosol] (Rattus norvegicus)
RHOD:GDP [cytosol] (Schizosaccharomyces pombe)
RHOD:GDP [cytosol] (Gallus gallus)
RHOD:GDP [cytosol] (Homo sapiens)
RHOF:GDP [plasma membrane] (Danio rerio)
RHOF:GDP [plasma membrane] (Mus musculus)
RHOF:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOF:GDP [plasma membrane] (Drosophila melanogaster)
RHOF:GDP [plasma membrane] (Rattus norvegicus)
RHOF:GDP [plasma membrane] (Caenorhabditis elegans)
RHOF:GDP [plasma membrane] (Canis familiaris)
RHOF:GDP [plasma membrane] (Sus scrofa)
RHOF:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOF:GDP [plasma membrane] (Xenopus tropicalis)
RHOF:GDP [plasma membrane] (Gallus gallus)
RHOF:GDP [plasma membrane] (Bos taurus)
RHOF:GDP [plasma membrane] (Homo sapiens)
RHOB:GDP [cytosol] (Canis familiaris)
RHOB:GDP [cytosol] (Schizosaccharomyces pombe)
RHOB:GDP [cytosol] (Caenorhabditis elegans)
RHOB:GDP [cytosol] (Drosophila melanogaster)
RHOB:GDP [cytosol] (Saccharomyces cerevisiae)
RHOB:GDP [cytosol] (Rattus norvegicus)
RHOB:GDP [cytosol] (Sus scrofa)
RHOB:GDP [cytosol] (Mus musculus)
RHOB:GDP [cytosol] (Homo sapiens)
RHOB:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOB:GDP [plasma membrane] (Rattus norvegicus)
RHOB:GDP [plasma membrane] (Caenorhabditis elegans)
RHOB:GDP [plasma membrane] (Xenopus tropicalis)
RHOB:GDP [plasma membrane] (Mus musculus)
RHOB:GDP [plasma membrane] (Gallus gallus)
RHOB:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOB:GDP [plasma membrane] (Sus scrofa)
RHOB:GDP [plasma membrane] (Drosophila melanogaster)
RHOB:GDP [plasma membrane] (Canis familiaris)
RHOB:GDP [plasma membrane] (Homo sapiens)
RHOG:GDP [cytosol] (Drosophila melanogaster)
RHOG:GDP [cytosol] (Rattus norvegicus)
RHOG:GDP [cytosol] (Caenorhabditis elegans)
RHOG:GDP [cytosol] (Xenopus tropicalis)
RHOG:GDP [cytosol] (Mus musculus)
RHOG:GDP [cytosol] (Canis familiaris)
RHOG:GDP [cytosol] (Gallus gallus)
RHOG:GDP [cytosol] (Danio rerio)
RHOG:GDP [cytosol] (Sus scrofa)
RHOG:GDP [cytosol] (Dictyostelium discoideum)
RHOG:GDP [cytosol] (Bos taurus)
RHOG:GDP [cytosol] (Homo sapiens)
RHOG:GDP [plasma membrane] (Caenorhabditis elegans)
RHOG:GDP [plasma membrane] (Xenopus tropicalis)
RHOG:GDP [plasma membrane] (Rattus norvegicus)
RHOG:GDP [plasma membrane] (Gallus gallus)
RHOG:GDP [plasma membrane] (Dictyostelium discoideum)
RHOG:GDP [plasma membrane] (Canis familiaris)
RHOG:GDP [plasma membrane] (Mus musculus)
RHOG:GDP [plasma membrane] (Drosophila melanogaster)
RHOG:GDP [plasma membrane] (Sus scrofa)
RHOG:GDP [plasma membrane] (Danio rerio)
RHOG:GDP [plasma membrane] (Bos taurus)
RHOG:GDP [plasma membrane] (Homo sapiens)
RHOJ:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOJ:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOJ:GDP [plasma membrane] (Dictyostelium discoideum)
RHOJ:GDP [plasma membrane] (Drosophila melanogaster)
RHOJ:GDP [plasma membrane] (Xenopus tropicalis)
RHOJ:GDP [plasma membrane] (Mus musculus)
RHOJ:GDP [plasma membrane] (Gallus gallus)
RHOJ:GDP [plasma membrane] (Sus scrofa)
RHOJ:GDP [plasma membrane] (Canis familiaris)
RHOJ:GDP [plasma membrane] (Rattus norvegicus)
RHOJ:GDP [plasma membrane] (Bos taurus)
RHOJ:GDP [plasma membrane] (Caenorhabditis elegans)
RHOJ:GDP [plasma membrane] (Homo sapiens)
RAC3:GDP [cytosol] (Danio rerio)
RAC3:GDP [cytosol] (Mus musculus)
RAC3:GDP [cytosol] (Canis familiaris)
RAC3:GDP [cytosol] (Sus scrofa)
RAC3:GDP [cytosol] (Gallus gallus)
RAC3:GDP [cytosol] (Xenopus tropicalis)
RAC3:GDP [cytosol] (Bos taurus)
RAC3:GDP [cytosol] (Homo sapiens)
RAC3:GDP [plasma membrane] (Mus musculus)
RAC3:GDP [plasma membrane] (Danio rerio)
RAC3:GDP [plasma membrane] (Canis familiaris)
RAC3:GDP [plasma membrane] (Sus scrofa)
RAC3:GDP [plasma membrane] (Gallus gallus)
RAC3:GDP [plasma membrane] (Xenopus tropicalis)
RAC3:GDP [plasma membrane] (Bos taurus)
RAC3:GDP [plasma membrane] (Homo sapiens)
p-Y254-RHOU:GDP [endosome membrane] (Danio rerio)
p-Y254-RHOU:GDP [endosome membrane] (Dictyostelium discoideum)
p-Y254-RHOU:GDP [endosome membrane] (Gallus gallus)
p-Y254-RHOU:GDP [endosome membrane] (Saccharomyces cerevisiae)
p-Y254-RHOU:GDP [endosome membrane] (Caenorhabditis elegans)
p-Y254-RHOU:GDP [endosome membrane] (Sus scrofa)
p-Y254-RHOU:GDP [endosome membrane] (Drosophila melanogaster)
p-Y254-RHOU:GDP [endosome membrane] (Rattus norvegicus)
p-Y254-RHOU:GDP [endosome membrane] (Bos taurus)
p-Y254-RHOU:GDP [endosome membrane] (Xenopus tropicalis)
p-Y254-RHOU:GDP [endosome membrane] (Canis familiaris)
p-Y254-RHOU:GDP [endosome membrane] (Mus musculus)
p-Y254-RHOU:GDP [endosome membrane] (Schizosaccharomyces pombe)
p-Y254-RHOU:GDP [endosome membrane] (Homo sapiens)
p-Y254-RHOU:GDP [plasma membrane] (Dictyostelium discoideum)
p-Y254-RHOU:GDP [plasma membrane] (Caenorhabditis elegans)
p-Y254-RHOU:GDP [plasma membrane] (Sus scrofa)
p-Y254-RHOU:GDP [plasma membrane] (Gallus gallus)
p-Y254-RHOU:GDP [plasma membrane] (Saccharomyces cerevisiae)
p-Y254-RHOU:GDP [plasma membrane] (Drosophila melanogaster)
p-Y254-RHOU:GDP [plasma membrane] (Rattus norvegicus)
p-Y254-RHOU:GDP [plasma membrane] (Bos taurus)
p-Y254-RHOU:GDP [plasma membrane] (Canis familiaris)
p-Y254-RHOU:GDP [plasma membrane] (Mus musculus)
p-Y254-RHOU:GDP [plasma membrane] (Xenopus tropicalis)
p-Y254-RHOU:GDP [plasma membrane] (Schizosaccharomyces pombe)
p-Y254-RHOU:GDP [plasma membrane] (Danio rerio)
p-Y254-RHOU:GDP [plasma membrane] (Homo sapiens)
RHOU:GDP [plasma membrane] (Sus scrofa)
RHOU:GDP [plasma membrane] (Dictyostelium discoideum)
RHOU:GDP [plasma membrane] (Bos taurus)
RHOU:GDP [plasma membrane] (Xenopus tropicalis)
RHOU:GDP [plasma membrane] (Danio rerio)
RHOU:GDP [plasma membrane] (Mus musculus)
RHOU:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOU:GDP [plasma membrane] (Gallus gallus)
RHOU:GDP [plasma membrane] (Canis familiaris)
RHOU:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOU:GDP [plasma membrane] (Caenorhabditis elegans)
RHOU:GDP [plasma membrane] (Drosophila melanogaster)
RHOU:GDP [plasma membrane] (Rattus norvegicus)
RHOU:GDP [plasma membrane] (Homo sapiens)
RHOQ:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOQ:GDP [plasma membrane] (Bos taurus)
RHOQ:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOQ:GDP [plasma membrane] (Dictyostelium discoideum)
RHOQ:GDP [plasma membrane] (Danio rerio)
RHOQ:GDP [plasma membrane] (Mus musculus)
RHOQ:GDP [plasma membrane] (Canis familiaris)
RHOQ:GDP [plasma membrane] (Rattus norvegicus)
RHOQ:GDP [plasma membrane] (Drosophila melanogaster)
RHOQ:GDP [plasma membrane] (Gallus gallus)
RHOQ:GDP [plasma membrane] (Caenorhabditis elegans)
RHOQ:GDP [plasma membrane] (Xenopus tropicalis)
RHOQ:GDP [plasma membrane] (Sus scrofa)
RHOQ:GDP [plasma membrane] (Homo sapiens)
Gnal:GDP [plasma membrane] (Rattus norvegicus)
Gnat3:GDP [plasma membrane] (Mus musculus)
Gnat3:GDP [plasma membrane] (Rattus norvegicus)
GNAT3:GDP [plasma membrane] (Danio rerio)
GNAT3:GDP [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Gallus gallus)
GNAT3:GDP [plasma membrane] (Mus musculus)
GNAT3:GDP [plasma membrane] (Canis familiaris)
GNAT3:GDP [plasma membrane] (Sus scrofa)
GNAT3:GDP [plasma membrane] (Homo sapiens)
ARF4:GDP [cytosol] (Sus scrofa)
ARF4:GDP [cytosol] (Bos taurus)
ARF4:GDP [cytosol] (Dictyostelium discoideum)
ARF4:GDP [cytosol] (Schizosaccharomyces pombe)
ARF4:GDP [cytosol] (Danio rerio)
ARF4:GDP [cytosol] (Rattus norvegicus)
ARF4:GDP [cytosol] (Plasmodium falciparum)
ARF4:GDP [cytosol] (Canis familiaris)
ARF4:GDP [cytosol] (Mus musculus)
ARF4:GDP [cytosol] (Gallus gallus)
ARF4:GDP [cytosol] (Saccharomyces cerevisiae)
ARF4:GDP [cytosol] (Drosophila melanogaster)
ARF4:GDP [cytosol] (Homo sapiens)
RAB8A:GDP [cytosol] (Rattus norvegicus)
RAB8A:GDP [cytosol] (Danio rerio)
RAB8A:GDP [cytosol] (Mus musculus)
RAB8A:GDP [cytosol] (Dictyostelium discoideum)
RAB8A:GDP [cytosol] (Caenorhabditis elegans)
RAB8A:GDP [cytosol] (Drosophila melanogaster)
RAB8A:GDP [cytosol] (Bos taurus)
RAB8A:GDP [cytosol] (Xenopus tropicalis)
RAB8A:GDP [cytosol] (Saccharomyces cerevisiae)
RAB8A:GDP [cytosol] (Gallus gallus)
RAB8A:GDP [cytosol] (Sus scrofa)
RAB8A:GDP [cytosol] (Schizosaccharomyces pombe)
RAB8A:GDP [cytosol] (Canis familiaris)
RAB8A:GDP [cytosol] (Homo sapiens)
GDP bound eRF3 [cytosol] (Saccharomyces cerevisiae)
GGC-RABs:GDP [cytosol] (Schizosaccharomyces pombe)
GGC-RABs:GDP [cytosol] (Caenorhabditis elegans)
GGC-RABs:GDP [cytosol] (Xenopus tropicalis)
GGC-RABs:GDP [cytosol] (Bos taurus)
GGC-RABs:GDP [cytosol] (Saccharomyces cerevisiae)
GGC-RABs:GDP [cytosol] (Gallus gallus)
GGC-RABs:GDP [cytosol] (Rattus norvegicus)
GGC-RABs:GDP [cytosol] (Danio rerio)
GGC-RABs:GDP [cytosol] (Sus scrofa)
GGC-RABs:GDP [cytosol] (Mus musculus)
GGC-RABs:GDP [cytosol] (Drosophila melanogaster)
GGC-RABs:GDP [cytosol] (Dictyostelium discoideum)
GGC-RABs:GDP [cytosol] (Plasmodium falciparum)
GGC-RABs:GDP [cytosol] (Canis familiaris)
GGC-RABs:GDP [cytosol] (Homo sapiens)
RABs:GDP [cytosol] (Xenopus tropicalis)
RABs:GDP [cytosol] (Dictyostelium discoideum)
RABs:GDP [cytosol] (Bos taurus)
RABs:GDP [cytosol] (Mus musculus)
RABs:GDP [cytosol] (Drosophila melanogaster)
RABs:GDP [cytosol] (Plasmodium falciparum)
RABs:GDP [cytosol] (Danio rerio)
RABs:GDP [cytosol] (Canis familiaris)
RABs:GDP [cytosol] (Sus scrofa)
RABs:GDP [cytosol] (Rattus norvegicus)
RABs:GDP [cytosol] (Schizosaccharomyces pombe)
RABs:GDP [cytosol] (Caenorhabditis elegans)
RABs:GDP [cytosol] (Saccharomyces cerevisiae)
RABs:GDP [cytosol] (Gallus gallus)
RABs:GDP [cytosol] (Homo sapiens)
Polyglycyl beta tubulin:GDP [cytosol] (Plasmodium falciparum)
Polyglycyl beta tubulin:GDP [cytosol] (Sus scrofa)
Polyglycyl beta tubulin:GDP [cytosol] (Dictyostelium discoideum)
Polyglycyl beta tubulin:GDP [cytosol] (Mus musculus)
Polyglycyl beta tubulin:GDP [cytosol] (Canis familiaris)
Polyglycyl beta tubulin:GDP [cytosol] (Rattus norvegicus)
Polyglycyl beta tubulin:GDP [cytosol] (Xenopus tropicalis)
Polyglycyl beta tubulin:GDP [cytosol] (Bos taurus)
Polyglycyl beta tubulin:GDP [cytosol] (Homo sapiens)
Polyglutamyl beta tubulin:GDP [cytosol] (Canis familiaris)
Polyglutamyl beta tubulin:GDP [cytosol] (Bos taurus)
Polyglutamyl beta tubulin:GDP [cytosol] (Mus musculus)
Polyglutamyl beta tubulin:GDP [cytosol] (Rattus norvegicus)
Polyglutamyl beta tubulin:GDP [cytosol] (Xenopus tropicalis)
Polyglutamyl beta tubulin:GDP [cytosol] (Plasmodium falciparum)
Polyglutamyl beta tubulin:GDP [cytosol] (Dictyostelium discoideum)
Polyglutamyl beta tubulin:GDP [cytosol] (Sus scrofa)
Polyglutamyl beta tubulin:GDP [cytosol] (Homo sapiens)
TUBB4A:GDP [cytosol] (Bos taurus)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Xenopus tropicalis)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Danio rerio)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Bos taurus)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Mus musculus)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Gallus gallus)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Dictyostelium discoideum)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Sus scrofa)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Homo sapiens)
Arf1-GDP [cytosol] (Canis familiaris)
Arf1-GDP [cytosol] (Drosophila melanogaster)
Arf1-GDP [cytosol] (Bos taurus)
Arf1-GDP [cytosol] (Mus musculus)
Arf1-GDP [cytosol] (Plasmodium falciparum)
Arf1-GDP [cytosol] (Saccharomyces cerevisiae)
Arf1-GDP [cytosol] (Sus scrofa)
Arf1-GDP [cytosol] (Rattus norvegicus)
Arf1-GDP [cytosol] (Schizosaccharomyces pombe)
Arf1-GDP [cytosol] (Danio rerio)
Arf1-GDP [cytosol] (Dictyostelium discoideum)
Arf1-GDP [cytosol] (Xenopus tropicalis)
Arf1-GDP [cytosol] (Caenorhabditis elegans)
Arf1-GDP [cytosol] (Gallus gallus)
Arf1-GDP [cytosol] (Homo sapiens)
Kras:GDP [plasma membrane] (Mus musculus)
S-Farn-Me-PalmS KRAS:GDP [plasma membrane] (Homo sapiens)
VAV1 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
VAV1 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
VAV1 Rho/Rac effectors:GDP [cytosol] (Caenorhabditis elegans)
VAV1 Rho/Rac effectors:GDP [cytosol] (Dictyostelium discoideum)
VAV1 Rho/Rac effectors:GDP [cytosol] (Xenopus tropicalis)
VAV1 Rho/Rac effectors:GDP [cytosol] (Danio rerio)
VAV1 Rho/Rac effectors:GDP [cytosol] (Canis familiaris)
VAV1 Rho/Rac effectors:GDP [cytosol] (Gallus gallus)
VAV1 Rho/Rac effectors:GDP [cytosol] (Sus scrofa)
VAV1 Rho/Rac effectors:GDP [cytosol] (Rattus norvegicus)
VAV1 Rho/Rac effectors:GDP [cytosol] (Mus musculus)
VAV1 Rho/Rac effectors:GDP [cytosol] (Homo sapiens)
RAC1:6TGTP [plasma membrane] (Homo sapiens)
G-alpha(i,o):GDP [plasma membrane] (Caenorhabditis elegans)
G-alpha(i,o):GDP [plasma membrane] (Canis familiaris)
G-alpha(i,o):GDP [plasma membrane] (Rattus norvegicus)
G-alpha(i,o):GDP [plasma membrane] (Mus musculus)
G-alpha(i,o):GDP [plasma membrane] (Drosophila melanogaster)
G-alpha(i,o):GDP [plasma membrane] (Danio rerio)
G-alpha(i,o):GDP [plasma membrane] (Sus scrofa)
G-alpha(i,o):GDP [plasma membrane] (Bos taurus)
G-alpha(i,o):GDP [plasma membrane] (Xenopus tropicalis)
G-alpha(i,o):GDP [plasma membrane] (Homo sapiens)
Gnat1-GDP [photoreceptor disc membrane] (Bos taurus)
GNAT1-GDP [photoreceptor disc membrane] (Sus scrofa)
GNAT1-GDP [photoreceptor disc membrane] (Bos taurus)
GNAT1-GDP [photoreceptor disc membrane] (Xenopus tropicalis)
GNAT1-GDP [photoreceptor disc membrane] (Mus musculus)
GNAT1-GDP [photoreceptor disc membrane] (Canis familiaris)
GNAT1-GDP [photoreceptor disc membrane] (Rattus norvegicus)
GNAT1-GDP [photoreceptor disc membrane] (Homo sapiens)
RAB5A,RAB7A:GDP [cytosol] (Homo sapiens)
Cdc42:GDP [cytosol] (Mus musculus)
eRF3:GDP [cytosol] (Plasmodium falciparum)
eRF3:GDP [cytosol] (Dictyostelium discoideum)
eRF3:GDP [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Sus scrofa)
eRF3:GDP [cytosol] (Caenorhabditis elegans)
eRF3:GDP [cytosol] (Rattus norvegicus)
eRF3:GDP [cytosol] (Saccharomyces cerevisiae)
eRF3:GDP [cytosol] (Drosophila melanogaster)
eRF3:GDP [cytosol] (Xenopus tropicalis)
eRF3:GDP [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Canis familiaris)
eRF3:GDP [cytosol] (Schizosaccharomyces pombe)
eRF3:GDP [cytosol] (Mus musculus)
eRF3:GDP [cytosol] (Gallus gallus)
eRF3:GDP [cytosol] (Homo sapiens)
RRAGB:GDP [cytosol] (Sus scrofa)
RRAGB:GDP [cytosol] (Bos taurus)
RRAGB:GDP [cytosol] (Canis familiaris)
RRAGB:GDP [cytosol] (Xenopus tropicalis)
RRAGB:GDP [cytosol] (Schizosaccharomyces pombe)
RRAGB:GDP [cytosol] (Gallus gallus)
RRAGB:GDP [cytosol] (Rattus norvegicus)
RRAGB:GDP [cytosol] (Danio rerio)
RRAGB:GDP [cytosol] (Saccharomyces cerevisiae)
RRAGB:GDP [cytosol] (Dictyostelium discoideum)
RRAGB:GDP [cytosol] (Caenorhabditis elegans)
RRAGB:GDP [cytosol] (Drosophila melanogaster)
RRAGB:GDP [cytosol] (Mus musculus)
RRAGB:GDP [cytosol] (Homo sapiens)
RRAGA:GDP [cytosol] (Danio rerio)
RRAGA:GDP [cytosol] (Caenorhabditis elegans)
RRAGA:GDP [cytosol] (Gallus gallus)
RRAGA:GDP [cytosol] (Saccharomyces cerevisiae)
RRAGA:GDP [cytosol] (Drosophila melanogaster)
RRAGA:GDP [cytosol] (Canis familiaris)
RRAGA:GDP [cytosol] (Rattus norvegicus)
RRAGA:GDP [cytosol] (Schizosaccharomyces pombe)
RRAGA:GDP [cytosol] (Mus musculus)
RRAGA:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Sus scrofa)
RRAGA:GDP [cytosol] (Dictyostelium discoideum)
RRAGA:GDP [cytosol] (Xenopus tropicalis)
RRAGA:GDP [cytosol] (Homo sapiens)
eEF2:GDP [cytosol] (Homo sapiens)
reEF1A:GDP [cytosol] (Oryctolagus cuniculus)
eEF1B:GDP exchange complex [cytosol] (Canis familiaris)
eEF1B:GDP exchange complex [cytosol] (Rattus norvegicus)
eEF1B:GDP exchange complex [cytosol] (Sus scrofa)
eEF1B:GDP exchange complex [cytosol] (Bos taurus)
eEF1B:GDP exchange complex [cytosol] (Mus musculus)
eEF1B:GDP exchange complex [cytosol] (Dictyostelium discoideum)
eEF1B:GDP exchange complex [cytosol] (Drosophila melanogaster)
eEF1B:GDP exchange complex [cytosol] (Schizosaccharomyces pombe)
eEF1B:GDP exchange complex [cytosol] (Saccharomyces cerevisiae)
eEF1B:GDP exchange complex [cytosol] (Homo sapiens)
eEF1A:GDP [cytosol] (Danio rerio)
eEF1A:GDP [cytosol] (Bos taurus)
eEF1A:GDP [cytosol] (Gallus gallus)
eEF1A:GDP [cytosol] (Rattus norvegicus)
eEF1A:GDP [cytosol] (Mus musculus)
eEF1A:GDP [cytosol] (Schizosaccharomyces pombe)
eEF1A:GDP [cytosol] (Drosophila melanogaster)
eEF1A:GDP [cytosol] (Xenopus tropicalis)
eEF1A:GDP [cytosol] (Sus scrofa)
eEF1A:GDP [cytosol] (Dictyostelium discoideum)
eEF1A:GDP [cytosol] (Caenorhabditis elegans)
eEF1A:GDP [cytosol] (Canis familiaris)
eEF1A:GDP [cytosol] (Plasmodium falciparum)
eEF1A:GDP [cytosol] (Saccharomyces cerevisiae)
eEF1A:GDP [cytosol] (Homo sapiens)
beta tubulin:GDP [axonemal microtubule] (Rattus norvegicus)
beta tubulin:GDP [axonemal microtubule] (Xenopus tropicalis)
beta tubulin:GDP [axonemal microtubule] (Plasmodium falciparum)
beta tubulin:GDP [axonemal microtubule] (Canis familiaris)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Mus musculus)
beta tubulin:GDP [axonemal microtubule] (Gallus gallus)
beta tubulin:GDP [axonemal microtubule] (Dictyostelium discoideum)
beta tubulin:GDP [axonemal microtubule] (Caenorhabditis elegans)
beta tubulin:GDP [axonemal microtubule] (Sus scrofa)
beta tubulin:GDP [axonemal microtubule] (Homo sapiens)
Ran GTPase:GDP [cytosol] (Homo sapiens)
Crm1:Ran GTPase:GDP [cytosol] (Homo sapiens)
eIF5B:GDP [cytosol] (Bos taurus)
eIF5B:GDP [cytosol] (Gallus gallus)
eIF5B:GDP [cytosol] (Plasmodium falciparum)
eIF5B:GDP [cytosol] (Schizosaccharomyces pombe)
eIF5B:GDP [cytosol] (Dictyostelium discoideum)
eIF5B:GDP [cytosol] (Saccharomyces cerevisiae)
eIF5B:GDP [cytosol] (Caenorhabditis elegans)
eIF5B:GDP [cytosol] (Rattus norvegicus)
eIF5B:GDP [cytosol] (Drosophila melanogaster)
eIF5B:GDP [cytosol] (Xenopus tropicalis)
eIF5B:GDP [cytosol] (Sus scrofa)
eIF5B:GDP [cytosol] (Canis familiaris)
eIF5B:GDP [cytosol] (Homo sapiens)
eIF5B:GDP [cytosol] (Mus musculus)
eIF2:GDP: eIF2B [cytosol] (Drosophila melanogaster)
eIF2:GDP: eIF2B [cytosol] (Canis familiaris)
eIF2:GDP: eIF2B [cytosol] (Gallus gallus)
eIF2:GDP: eIF2B [cytosol] (Dictyostelium discoideum)
eIF2:GDP: eIF2B [cytosol] (Plasmodium falciparum)
eIF2:GDP: eIF2B [cytosol] (Rattus norvegicus)
eIF2:GDP: eIF2B [cytosol] (Sus scrofa)
eIF2:GDP: eIF2B [cytosol] (Saccharomyces cerevisiae)
eIF2:GDP: eIF2B [cytosol] (Danio rerio)
eIF2:GDP: eIF2B [cytosol] (Schizosaccharomyces pombe)
eIF2:GDP: eIF2B [cytosol] (Caenorhabditis elegans)
eIF2:GDP: eIF2B [cytosol] (Xenopus tropicalis)
eIF2:GDP: eIF2B [cytosol] (Bos taurus)
eIF2:GDP: eIF2B [cytosol] (Homo sapiens)
eIF2:GDP [cytosol] (Saccharomyces cerevisiae)
eIF2:GDP [cytosol] (Schizosaccharomyces pombe)
eIF2:GDP [cytosol] (Sus scrofa)
eIF2:GDP [cytosol] (Gallus gallus)
eIF2:GDP [cytosol] (Xenopus tropicalis)
eIF2:GDP [cytosol] (Bos taurus)
eIF2:GDP [cytosol] (Plasmodium falciparum)
eIF2:GDP [cytosol] (Dictyostelium discoideum)
eIF2:GDP [cytosol] (Drosophila melanogaster)
eIF2:GDP [cytosol] (Danio rerio)
eIF2:GDP [cytosol] (Canis familiaris)
eIF2:GDP [cytosol] (Rattus norvegicus)
eIF2:GDP [cytosol] (Caenorhabditis elegans)
eIF2:GDP [cytosol] (Homo sapiens)
eIF2:GDP [cytosol] (Mus musculus)
eIF2:GDP: eIF2B [cytosol] (Mus musculus)
SAR1B:GDP [cytosol] (Dictyostelium discoideum)
SAR1B:GDP [cytosol] (Danio rerio)
SAR1B:GDP [cytosol] (Bos taurus)
SAR1B:GDP [cytosol] (Mus musculus)
SAR1B:GDP [cytosol] (Plasmodium falciparum)
SAR1B:GDP [cytosol] (Caenorhabditis elegans)
SAR1B:GDP [cytosol] (Schizosaccharomyces pombe)
SAR1B:GDP [cytosol] (Gallus gallus)
SAR1B:GDP [cytosol] (Rattus norvegicus)
SAR1B:GDP [cytosol] (Sus scrofa)
SAR1B:GDP [cytosol] (Xenopus tropicalis)
SAR1B:GDP [cytosol] (Canis familiaris)
SAR1B:GDP [cytosol] (Saccharomyces cerevisiae)
SAR1B:GDP [cytosol] (Drosophila melanogaster)
SAR1B:GDP [cytosol] (Homo sapiens)
ARF:GDP [cytosol] (Danio rerio)
ARF:GDP [cytosol] (Gallus gallus)
ARF:GDP [cytosol] (Schizosaccharomyces pombe)
ARF:GDP [cytosol] (Saccharomyces cerevisiae)
ARF:GDP [cytosol] (Dictyostelium discoideum)
ARF:GDP [cytosol] (Sus scrofa)
ARF:GDP [cytosol] (Mus musculus)
ARF:GDP [cytosol] (Plasmodium falciparum)
ARF:GDP [cytosol] (Canis familiaris)
ARF:GDP [cytosol] (Bos taurus)
ARF:GDP [cytosol] (Rattus norvegicus)
ARF:GDP [cytosol] (Drosophila melanogaster)
ARF:GDP [cytosol] (Caenorhabditis elegans)
ARF:GDP [cytosol] (Homo sapiens)
RAB1:GDP [cytosol] (Dictyostelium discoideum)
RAB1:GDP [cytosol] (Bos taurus)
RAB1:GDP [cytosol] (Caenorhabditis elegans)
RAB1:GDP [cytosol] (Rattus norvegicus)
RAB1:GDP [cytosol] (Sus scrofa)
RAB1:GDP [cytosol] (Mus musculus)
RAB1:GDP [cytosol] (Plasmodium falciparum)
RAB1:GDP [cytosol] (Xenopus tropicalis)
RAB1:GDP [cytosol] (Danio rerio)
RAB1:GDP [cytosol] (Canis familiaris)
RAB1:GDP [cytosol] (Drosophila melanogaster)
RAB1:GDP [cytosol] (Gallus gallus)
RAB1:GDP [cytosol] (Saccharomyces cerevisiae)
RAB1:GDP [cytosol] (Schizosaccharomyces pombe)
RAB1:GDP [cytosol] (Homo sapiens)
G alpha (q):GDP:RGS [plasma membrane] (Sus scrofa)
G alpha (q):GDP:RGS [plasma membrane] (Schizosaccharomyces pombe)
G alpha (q):GDP:RGS [plasma membrane] (Drosophila melanogaster)
G alpha (q):GDP:RGS [plasma membrane] (Saccharomyces cerevisiae)
G alpha (q):GDP:RGS [plasma membrane] (Dictyostelium discoideum)
G alpha (q):GDP:RGS [plasma membrane] (Danio rerio)
G alpha (q):GDP:RGS [plasma membrane] (Xenopus tropicalis)
G alpha (q):GDP:RGS [plasma membrane] (Bos taurus)
G alpha (q):GDP:RGS [plasma membrane] (Rattus norvegicus)
G alpha (q):GDP:RGS [plasma membrane] (Gallus gallus)
G alpha (q):GDP:RGS [plasma membrane] (Mus musculus)
G alpha (q):GDP:RGS [plasma membrane] (Caenorhabditis elegans)
G alpha (q):GDP:RGS [plasma membrane] (Canis familiaris)
G alpha (q):GDP:RGS [plasma membrane] (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Rattus norvegicus)
G alpha (i):GDP:RGS [plasma membrane] (Saccharomyces cerevisiae)
G alpha (i):GDP:RGS [plasma membrane] (Dictyostelium discoideum)
G alpha (i):GDP:RGS [plasma membrane] (Mus musculus)
G alpha (i):GDP:RGS [plasma membrane] (Canis familiaris)
G alpha (i):GDP:RGS [plasma membrane] (Xenopus tropicalis)
G alpha (i):GDP:RGS [plasma membrane] (Sus scrofa)
G alpha (i):GDP:RGS [plasma membrane] (Gallus gallus)
G alpha (i):GDP:RGS [plasma membrane] (Caenorhabditis elegans)
G alpha (i):GDP:RGS [plasma membrane] (Schizosaccharomyces pombe)
G alpha (i):GDP:RGS [plasma membrane] (Drosophila melanogaster)
G alpha (i):GDP:RGS [plasma membrane] (Danio rerio)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
G-protein alpha:GDP [plasma membrane] (Dictyostelium discoideum)
G-protein alpha:GDP [plasma membrane] (Drosophila melanogaster)
G-protein alpha:GDP [plasma membrane] (Saccharomyces cerevisiae)
G-protein alpha:GDP [plasma membrane] (Mus musculus)
G-protein alpha:GDP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha:GDP [plasma membrane] (Gallus gallus)
G-protein alpha:GDP [plasma membrane] (Danio rerio)
G-protein alpha:GDP [plasma membrane] (Sus scrofa)
G-protein alpha:GDP [plasma membrane] (Schizosaccharomyces pombe)
G-protein alpha:GDP [plasma membrane] (Rattus norvegicus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Canis familiaris)
G-protein alpha:GDP [plasma membrane] (Xenopus tropicalis)
G-protein alpha:GDP [plasma membrane] (Homo sapiens)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Xenopus tropicalis)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Dictyostelium discoideum)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Caenorhabditis elegans)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Gallus gallus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Bos taurus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Schizosaccharomyces pombe)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Rattus norvegicus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Sus scrofa)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Mus musculus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Saccharomyces cerevisiae)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Canis familiaris)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Homo sapiens)
Eefsec:GDP [cytosol] (Rattus norvegicus)
EEFSEC:GDP [cytosol] (Homo sapiens)
RAN:GDP [cytosol] (Danio rerio)
RAN:GDP [cytosol] (Dictyostelium discoideum)
RAN:GDP [cytosol] (Drosophila melanogaster)
RAN:GDP [cytosol] (Schizosaccharomyces pombe)
RAN:GDP [cytosol] (Caenorhabditis elegans)
RAN:GDP [cytosol] (Sus scrofa)
RAN:GDP [cytosol] (Gallus gallus)
RAN:GDP [cytosol] (Canis familiaris)
RAN:GDP [cytosol] (Bos taurus)
RAN:GDP [cytosol] (Saccharomyces cerevisiae)
RAN:GDP [cytosol] (Rattus norvegicus)
RAN:GDP [cytosol] (Xenopus tropicalis)
RAN:GDP [cytosol] (Mus musculus)
RAN:GDP [cytosol] (Homo sapiens)
RAN:GDP [cytosol] (Plasmodium falciparum)
G alpha-olf:GDP complex [plasma membrane] (Dictyostelium discoideum)
G alpha-olf:GDP complex [plasma membrane] (Xenopus tropicalis)
G alpha-olf:GDP complex [plasma membrane] (Danio rerio)
G alpha-olf:GDP complex [plasma membrane] (Sus scrofa)
G alpha-olf:GDP complex [plasma membrane] (Rattus norvegicus)
G alpha-olf:GDP complex [plasma membrane] (Mus musculus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Gallus gallus)
G alpha-olf:GDP complex [plasma membrane] (Drosophila melanogaster)
G alpha-olf:GDP complex [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GDP complex [plasma membrane] (Canis familiaris)
G alpha-olf:GDP complex [plasma membrane] (Homo sapiens)
RAP1:GDP [plasma membrane] (Dictyostelium discoideum)
RAP1:GDP [plasma membrane] (Bos taurus)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Rattus norvegicus)
RAP1:GDP [plasma membrane] (Danio rerio)
RAP1:GDP [plasma membrane] (Sus scrofa)
RAP1:GDP [plasma membrane] (Saccharomyces cerevisiae)
RAP1:GDP [plasma membrane] (Mus musculus)
RAP1:GDP [plasma membrane] (Drosophila melanogaster)
RAP1:GDP [plasma membrane] (Xenopus tropicalis)
RAP1:GDP [plasma membrane] (Canis familiaris)
RAP1:GDP [plasma membrane] (Homo sapiens)
RAP1:GDP [plasma membrane] (Gallus gallus)
RIT/RIN-GDP [plasma membrane] (Homo sapiens)
Rap1-GDP [cytosol] (Dictyostelium discoideum)
Rap1-GDP [cytosol] (Drosophila melanogaster)
Rap1-GDP [cytosol] (Rattus norvegicus)
Rap1-GDP [cytosol] (Mus musculus)
Rap1-GDP [cytosol] (Canis familiaris)
Rap1-GDP [cytosol] (Gallus gallus)
Rap1-GDP [cytosol] (Caenorhabditis elegans)
Rap1-GDP [cytosol] (Saccharomyces cerevisiae)
Rap1-GDP [cytosol] (Xenopus tropicalis)
Rap1-GDP [cytosol] (Bos taurus)
Rap1-GDP [cytosol] (Danio rerio)
Rap1-GDP [cytosol] (Homo sapiens)
Rap1-GDP [cytosol] (Sus scrofa)
RalA-GDP [cytosol] (Rattus norvegicus)
RalB-GDP [cytosol] (Rattus norvegicus)
RALB-GDP [cytosol] (Homo sapiens)
RALA-GDP [cytosol] (Homo sapiens)
beta-tubulin:GDP [cytosol] (Bos taurus)
HRAS:GDP [plasma membrane] (Mus musculus)
HRAS:GDP [plasma membrane] (Sus scrofa)
HRAS:GDP [plasma membrane] (Canis familiaris)
HRAS:GDP [plasma membrane] (Xenopus tropicalis)
HRAS:GDP [plasma membrane] (Rattus norvegicus)
HRAS:GDP [plasma membrane] (Danio rerio)
HRAS:GDP [plasma membrane] (Caenorhabditis elegans)
HRAS:GDP [plasma membrane] (Bos taurus)
HRAS:GDP [plasma membrane] (Drosophila melanogaster)
HRAS:GDP [plasma membrane] (Gallus gallus)
HRAS:GDP [plasma membrane] (Homo sapiens)
p21 Ras:GDP [plasma membrane] (Rattus norvegicus)
R-Ras-GDP [cytosol] (Mus musculus)
VAV3 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
VAV3 Rho/Rac effectors:GDP [cytosol] (Dictyostelium discoideum)
VAV3 Rho/Rac effectors:GDP [cytosol] (Canis familiaris)
VAV3 Rho/Rac effectors:GDP [cytosol] (Gallus gallus)
VAV3 Rho/Rac effectors:GDP [cytosol] (Mus musculus)
VAV3 Rho/Rac effectors:GDP [cytosol] (Schizosaccharomyces pombe)
VAV3 Rho/Rac effectors:GDP [cytosol] (Sus scrofa)
VAV3 Rho/Rac effectors:GDP [cytosol] (Saccharomyces cerevisiae)
VAV3 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
VAV3 Rho/Rac effectors:GDP [cytosol] (Caenorhabditis elegans)
VAV3 Rho/Rac effectors:GDP [cytosol] (Danio rerio)
VAV3 Rho/Rac effectors:GDP [cytosol] (Rattus norvegicus)
VAV3 Rho/Rac effectors:GDP [cytosol] (Xenopus tropicalis)
VAV3 Rho/Rac effectors:GDP [cytosol] (Homo sapiens)
VAV2 Rho/Rac effectors:GDP [cytosol] (Dictyostelium discoideum)
VAV2 Rho/Rac effectors:GDP [cytosol] (Xenopus tropicalis)
VAV2 Rho/Rac effectors:GDP [cytosol] (Sus scrofa)
VAV2 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
VAV2 Rho/Rac effectors:GDP [cytosol] (Schizosaccharomyces pombe)
VAV2 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
VAV2 Rho/Rac effectors:GDP [cytosol] (Danio rerio)
VAV2 Rho/Rac effectors:GDP [cytosol] (Canis familiaris)
VAV2 Rho/Rac effectors:GDP [cytosol] (Mus musculus)
VAV2 Rho/Rac effectors:GDP [cytosol] (Gallus gallus)
VAV2 Rho/Rac effectors:GDP [cytosol] (Rattus norvegicus)
VAV2 Rho/Rac effectors:GDP [cytosol] (Caenorhabditis elegans)
VAV2 Rho/Rac effectors:GDP [cytosol] (Saccharomyces cerevisiae)
VAV2 Rho/Rac effectors:GDP [cytosol] (Homo sapiens)
CDC42:GDP [cytosol] (Bos taurus)
CDC42:GDP [cytosol] (Canis familiaris)
CDC42:GDP [cytosol] (Mus musculus)
CDC42:GDP [cytosol] (Xenopus tropicalis)
CDC42:GDP [cytosol] (Rattus norvegicus)
CDC42:GDP [cytosol] (Schizosaccharomyces pombe)
CDC42:GDP [cytosol] (Caenorhabditis elegans)
CDC42:GDP [cytosol] (Sus scrofa)
CDC42:GDP [cytosol] (Saccharomyces cerevisiae)
CDC42:GDP [cytosol] (Gallus gallus)
CDC42:GDP [cytosol] (Dictyostelium discoideum)
CDC42:GDP [cytosol] (Drosophila melanogaster)
CDC42:GDP [cytosol] (Danio rerio)
CDC42:GDP [cytosol] (Homo sapiens)
RHOA:GDP [plasma membrane] (Caenorhabditis elegans)
RHOA:GDP [plasma membrane] (Gallus gallus)
RHOA:GDP [plasma membrane] (Rattus norvegicus)
RHOA:GDP [plasma membrane] (Schizosaccharomyces pombe)
RHOA:GDP [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Mus musculus)
RHOA:GDP [plasma membrane] (Xenopus tropicalis)
RHOA:GDP [plasma membrane] (Danio rerio)
RHOA:GDP [plasma membrane] (Sus scrofa)
RHOA:GDP [plasma membrane] (Saccharomyces cerevisiae)
RHOA:GDP [plasma membrane] (Canis familiaris)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Homo sapiens)
Ras:GDP [plasma membrane] (Mus musculus)
Rac1:GDP [plasma membrane] (Mus musculus)
RAC1:GDP [plasma membrane] (Drosophila melanogaster)
RAC1:GDP [plasma membrane] (Gallus gallus)
RAC1:GDP [plasma membrane] (Danio rerio)
RAC1:GDP [plasma membrane] (Canis familiaris)
RAC1:GDP [plasma membrane] (Xenopus tropicalis)
Rac1:GDP [plasma membrane] (Rattus norvegicus)
RAC1:GDP [plasma membrane] (Bos taurus)
RAC1:GDP [plasma membrane] (Sus scrofa)
RAC1:GDP [plasma membrane] (Caenorhabditis elegans)
RAC1:GDP [plasma membrane] (Dictyostelium discoideum)
RAC1:GDP [plasma membrane] (Homo sapiens)
RAC1:GDP [cytosol] (Dictyostelium discoideum)
RAC1:GDP [cytosol] (Sus scrofa)
RAC1:GDP [cytosol] (Bos taurus)
RAC1:GDP [cytosol] (Xenopus tropicalis)
RAC1:GDP [cytosol] (Gallus gallus)
RAC1:GDP [cytosol] (Mus musculus)
RAC1:GDP [cytosol] (Rattus norvegicus)
RAC1:GDP [cytosol] (Danio rerio)
Rac1:GDP [cytosol] (Drosophila melanogaster)
RAC1:GDP [cytosol] (Canis familiaris)
RAC1:GDP [cytosol] (Caenorhabditis elegans)
RAC1:GDP [cytosol] (Homo sapiens)
Rap1-GDP [cytosol] (Rattus norvegicus)
RAP1:GDP [endosome membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Drosophila melanogaster)
G alpha (s):GDP [plasma membrane] (Gallus gallus)
G alpha (s):GDP [plasma membrane] (Canis familiaris)
G alpha (s):GDP [plasma membrane] (Caenorhabditis elegans)
G alpha (s):GDP [plasma membrane] (Mus musculus)
G alpha (s):GDP [plasma membrane] (Sus scrofa)
G alpha (s):GDP [plasma membrane] (Xenopus tropicalis)
G alpha (s):GDP [plasma membrane] (Rattus norvegicus)
G alpha (s):GDP [plasma membrane] (Danio rerio)
G alpha (s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2):GDP [plasma membrane] (Canis familiaris)
G-protein alpha (o/t2):GDP [plasma membrane] (Xenopus tropicalis)
G-protein alpha (o/t2):GDP [plasma membrane] (Sus scrofa)
Gnao1/Gnat2:GDP [cytosol] (Mus musculus)
G-protein alpha (o/t2):GDP [plasma membrane] (Bos taurus)
G-protein alpha (o/t2):GDP [plasma membrane] (Rattus norvegicus)
G-protein alpha (o/t2):GDP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (o/t2):GDP [plasma membrane] (Gallus gallus)
G-protein alpha (o/t2):GDP [plasma membrane] (Drosophila melanogaster)
G-protein alpha (o/t2):GDP [plasma membrane] (Homo sapiens)
p21 RAS:GDP [plasma membrane] (Mus musculus)
p21 RAS:GDP [plasma membrane] (Danio rerio)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Xenopus tropicalis)
p21 RAS:GDP [plasma membrane] (Canis familiaris)
p21 RAS:GDP [plasma membrane] (Gallus gallus)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Homo sapiens)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Gallus gallus)
RHEB:GDP [lysosomal membrane] (Sus scrofa)
RHEB:GDP [lysosomal membrane] (Rattus norvegicus)
RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Canis familiaris)
RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GDP [lysosomal membrane] (Danio rerio)
RHEB:GDP [lysosomal membrane] (Mus musculus)
beta-tubulin:GDP [cytosol] (Homo sapiens)
beta-tubulin:GDP [cytosol] (Xenopus tropicalis)
beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
beta-tubulin:GDP [cytosol] (Schizosaccharomyces pombe)
beta-tubulin:GDP [cytosol] (Danio rerio)
beta-tubulin:GDP [cytosol] (Drosophila melanogaster)
beta-tubulin:GDP [cytosol] (Plasmodium falciparum)
beta-tubulin:GDP [cytosol] (Dictyostelium discoideum)
beta-tubulin:GDP [cytosol] (Rattus norvegicus)
beta-tubulin:GDP [cytosol] (Gallus gallus)
beta-tubulin:GDP [cytosol] (Canis familiaris)
beta-tubulin:GDP [cytosol] (Sus scrofa)
beta-tubulin:GDP [cytosol] (Mus musculus)
beta-tubulin:GDP [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Saccharomyces cerevisiae)
beta tubulin:GDP [cytosol] (Mus musculus)
RRAGC:GDP [cytosol] (Homo sapiens)
RRAGC:GDP [cytosol] (Drosophila melanogaster)
RRAGC:GDP [cytosol] (Saccharomyces cerevisiae)
RRAGC:GDP [cytosol] (Canis familiaris)
RRAGC:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Schizosaccharomyces pombe)
RRAGC:GDP [cytosol] (Mus musculus)
RRAGC:GDP [cytosol] (Caenorhabditis elegans)
RRAGC:GDP [cytosol] (Gallus gallus)
RRAGC:GDP [cytosol] (Rattus norvegicus)
RRAGC:GDP [cytosol] (Sus scrofa)
RRAGC:GDP [cytosol] (Danio rerio)
RRAGC:GDP [cytosol] (Dictyostelium discoideum)
RRAGD:GDP [cytosol] (Homo sapiens)
RRAGD:GDP [cytosol] (Gallus gallus)
RRAGD:GDP [cytosol] (Schizosaccharomyces pombe)
RRAGD:GDP [cytosol] (Rattus norvegicus)
RRAGD:GDP [cytosol] (Xenopus tropicalis)
RRAGD:GDP [cytosol] (Mus musculus)
RRAGD:GDP [cytosol] (Drosophila melanogaster)
RRAGD:GDP [cytosol] (Caenorhabditis elegans)
RRAGD:GDP [cytosol] (Dictyostelium discoideum)
RRAGD:GDP [cytosol] (Sus scrofa)
RRAGD:GDP [cytosol] (Canis familiaris)
RRAGD:GDP [cytosol] (Bos taurus)
RRAGD:GDP [cytosol] (Saccharomyces cerevisiae)
RHEB:GDP [lysosomal membrane] (Homo sapiens)
RHEB:GDP [lysosomal membrane] (Saccharomyces cerevisiae)
RHEB:GDP [lysosomal membrane] (Xenopus tropicalis)
RHEB:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
as an input of
Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Y-Crkl:p-Y-Shc1:Grb2-1:Sos1,p-Y-Vav1 mediates exchange of GDP for GTP bound to Ras (Mus musculus)
Inactivation of Rac1 (Drosophila melanogaster)
RRAGC,D exchanges GTP for GDP (Saccharomyces cerevisiae)
RRAGC,D exchanges GTP for GDP (Schizosaccharomyces pombe)
RRAGC,D exchanges GTP for GDP (Dictyostelium discoideum)
RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)
RRAGC,D exchanges GTP for GDP (Drosophila melanogaster)
RRAGC,D exchanges GTP for GDP (Gallus gallus)
RRAGC,D exchanges GTP for GDP (Xenopus tropicalis)
RRAGC,D exchanges GTP for GDP (Danio rerio)
RRAGC,D exchanges GTP for GDP (Sus scrofa)
RRAGC,D exchanges GTP for GDP (Bos taurus)
RRAGC,D exchanges GTP for GDP (Canis familiaris)
RRAGC,D exchanges GTP for GDP (Rattus norvegicus)
RRAGC,D exchanges GTP for GDP (Mus musculus)
RRAGC,D exchanges GTP for GDP (Homo sapiens)
Disassembly of COPII coated vesicle (Sus scrofa)
Disassembly of COPII coated vesicle (Bos taurus)
Disassembly of COPII coated vesicle (Canis familiaris)
Disassembly of COPII coated vesicle (Rattus norvegicus)
Disassembly of COPII coated vesicle (Mus musculus)
Disassembly of COPII coated vesicle (Homo sapiens)
Disassembly of COPII coated vesicle (Gallus gallus)
G-protein alpha subunit is inactivated (Saccharomyces cerevisiae)
G-protein alpha subunit is inactivated (Schizosaccharomyces pombe)
G-protein alpha subunit is inactivated (Dictyostelium discoideum)
G-protein alpha subunit is inactivated (Caenorhabditis elegans)
G-protein alpha subunit is inactivated (Drosophila melanogaster)
G-protein alpha subunit is inactivated (Danio rerio)
G-protein alpha subunit is inactivated (Rattus norvegicus)
G-protein alpha subunit is inactivated (Gallus gallus)
G-protein alpha subunit is inactivated (Xenopus tropicalis)
G-protein alpha subunit is inactivated (Sus scrofa)
G-protein alpha subunit is inactivated (Bos taurus)
G-protein alpha subunit is inactivated (Canis familiaris)
G-protein alpha subunit is inactivated (Mus musculus)
G-protein alpha subunit is inactivated (Homo sapiens)
mature p21 RAS binds GDP (Caenorhabditis elegans)
mature p21 RAS binds GDP (Drosophila melanogaster)
mature p21 RAS binds GDP (Gallus gallus)
mature p21 RAS binds GDP (Danio rerio)
mature p21 RAS binds GDP (Sus scrofa)
mature p21 RAS binds GDP (Canis familiaris)
mature p21 RAS binds GDP (Rattus norvegicus)
mature p21 RAS binds GDP (Mus musculus)
mature p21 RAS binds GDP (Homo sapiens)
mature p21 RAS binds GDP (Bos taurus)
as an output of
GDP is exchanged for GTP on DRheb (Drosophila melanogaster)
RHOGEF2 stimulates nucleotide exchange of RHO1:GDP complex (Drosophila melanogaster)
inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate (Mus musculus)
inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate (Gallus gallus)
oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] (Gallus gallus)
trans-Golgi Network Vesicle Scission (Caenorhabditis elegans)
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
trans-Golgi Network Vesicle Scission (Gallus gallus)
trans-Golgi Network Vesicle Scission (Xenopus tropicalis)
trans-Golgi Network Vesicle Scission (Sus scrofa)
trans-Golgi Network Vesicle Scission (Bos taurus)
trans-Golgi Network Vesicle Scission (Canis familiaris)
trans-Golgi Network Vesicle Scission (Rattus norvegicus)
trans-Golgi Network Vesicle Scission (Mus musculus)
trans-Golgi Network Vesicle Scission (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Caenorhabditis elegans)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Gallus gallus)
trans-Golgi Network Lysosomal Vesicle Scission (Xenopus tropicalis)
trans-Golgi Network Lysosomal Vesicle Scission (Danio rerio)
trans-Golgi Network Lysosomal Vesicle Scission (Sus scrofa)
trans-Golgi Network Lysosomal Vesicle Scission (Bos taurus)
trans-Golgi Network Lysosomal Vesicle Scission (Canis familiaris)
trans-Golgi Network Lysosomal Vesicle Scission (Rattus norvegicus)
trans-Golgi Network Lysosomal Vesicle Scission (Mus musculus)
trans-Golgi Network Coat Activation (Plasmodium falciparum)
trans-Golgi Network Coat Activation (Saccharomyces cerevisiae)
trans-Golgi Network Coat Activation (Schizosaccharomyces pombe)
trans-Golgi Network Coat Activation (Dictyostelium discoideum)
trans-Golgi Network Coat Activation (Caenorhabditis elegans)
trans-Golgi Network Coat Activation (Drosophila melanogaster)
trans-Golgi Network Coat Activation (Gallus gallus)
trans-Golgi Network Coat Activation (Sus scrofa)
trans-Golgi Network Coat Activation (Bos taurus)
trans-Golgi Network Coat Activation (Canis familiaris)
trans-Golgi Network Coat Activation (Rattus norvegicus)
trans-Golgi Network Coat Activation (Mus musculus)
trans-Golgi Network Coat Activation (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Homo sapiens)
GBF1 stimulates nucleotide exchange on ARF (Plasmodium falciparum)
GBF1 stimulates nucleotide exchange on ARF (Saccharomyces cerevisiae)
GBF1 stimulates nucleotide exchange on ARF (Schizosaccharomyces pombe)
GBF1 stimulates nucleotide exchange on ARF (Dictyostelium discoideum)
GBF1 stimulates nucleotide exchange on ARF (Drosophila melanogaster)
GBF1 stimulates nucleotide exchange on ARF (Bos taurus)
GBF1 stimulates nucleotide exchange on ARF (Canis familiaris)
GBF1 stimulates nucleotide exchange on ARF (Rattus norvegicus)
GBF1 stimulates nucleotide exchange on ARF (Mus musculus)
GBF1 stimulates nucleotide exchange on ARF (Homo sapiens)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Dictyostelium discoideum)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Caenorhabditis elegans)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Drosophila melanogaster)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Gallus gallus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Sus scrofa)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Bos taurus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Canis familiaris)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Rattus norvegicus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Mus musculus)
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Homo sapiens)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Saccharomyces cerevisiae)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Schizosaccharomyces pombe)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Dictyostelium discoideum)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Drosophila melanogaster)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Gallus gallus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Bos taurus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Rattus norvegicus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Mus musculus)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Homo sapiens)
RAB5 GEFs exchange GTP for GDP on RAB5 (Plasmodium falciparum)
RAB5 GEFs exchange GTP for GDP on RAB5 (Saccharomyces cerevisiae)
RAB5 GEFs exchange GTP for GDP on RAB5 (Schizosaccharomyces pombe)
RAB5 GEFs exchange GTP for GDP on RAB5 (Dictyostelium discoideum)
RAB5 GEFs exchange GTP for GDP on RAB5 (Caenorhabditis elegans)
RAB5 GEFs exchange GTP for GDP on RAB5 (Drosophila melanogaster)
RAB5 GEFs exchange GTP for GDP on RAB5 (Gallus gallus)
RAB5 GEFs exchange GTP for GDP on RAB5 (Danio rerio)
RAB5 GEFs exchange GTP for GDP on RAB5 (Sus scrofa)
RAB5 GEFs exchange GTP for GDP on RAB5 (Bos taurus)
RAB5 GEFs exchange GTP for GDP on RAB5 (Canis familiaris)
RAB5 GEFs exchange GTP for GDP on RAB5 (Rattus norvegicus)
RAB5 GEFs exchange GTP for GDP on RAB5 (Mus musculus)
RAB5 GEFs exchange GTP for GDP on RAB5 (Homo sapiens)
MADD exchanges GTP for GDP on RAB27 (Caenorhabditis elegans)
MADD exchanges GTP for GDP on RAB27 (Drosophila melanogaster)
MADD exchanges GTP for GDP on RAB27 (Gallus gallus)
MADD exchanges GTP for GDP on RAB27 (Sus scrofa)
MADD exchanges GTP for GDP on RAB27 (Bos taurus)
MADD exchanges GTP for GDP on RAB27 (Canis familiaris)
MADD exchanges GTP for GDP on RAB27 (Rattus norvegicus)
MADD exchanges GTP for GDP on RAB27 (Mus musculus)
MADD exchanges GTP for GDP on RAB27 (Homo sapiens)
DENND4s exchange GTP for GDP on RAB10 (Caenorhabditis elegans)
DENND4s exchange GTP for GDP on RAB10 (Drosophila melanogaster)
DENND4s exchange GTP for GDP on RAB10 (Gallus gallus)
DENND4s exchange GTP for GDP on RAB10 (Xenopus tropicalis)
DENND4s exchange GTP for GDP on RAB10 (Sus scrofa)
DENND4s exchange GTP for GDP on RAB10 (Bos taurus)
DENND4s exchange GTP for GDP on RAB10 (Canis familiaris)
DENND4s exchange GTP for GDP on RAB10 (Rattus norvegicus)
DENND4s exchange GTP for GDP on RAB10 (Mus musculus)
DENND4s exchange GTP for GDP on RAB10 (Homo sapiens)
RAB8 GEFs exchange GTP for GDP on RAB8 (Saccharomyces cerevisiae)
RAB8 GEFs exchange GTP for GDP on RAB8 (Schizosaccharomyces pombe)
RAB8 GEFs exchange GTP for GDP on RAB8 (Caenorhabditis elegans)
RAB8 GEFs exchange GTP for GDP on RAB8 (Gallus gallus)
RAB8 GEFs exchange GTP for GDP on RAB8 (Xenopus tropicalis)
RAB8 GEFs exchange GTP for GDP on RAB8 (Danio rerio)
RAB8 GEFs exchange GTP for GDP on RAB8 (Sus scrofa)
RAB8 GEFs exchange GTP for GDP on RAB8 (Bos taurus)
RAB8 GEFs exchange GTP for GDP on RAB8 (Canis familiaris)
RAB8 GEFs exchange GTP for GDP on RAB8 (Rattus norvegicus)
RAB8 GEFs exchange GTP for GDP on RAB8 (Mus musculus)
RAB8 GEFs exchange GTP for GDP on RAB8 (Homo sapiens)
RAB31 GEFs exchange GTP for GDP on RAB31 (Saccharomyces cerevisiae)
RAB31 GEFs exchange GTP for GDP on RAB31 (Gallus gallus)
RAB31 GEFs exchange GTP for GDP on RAB31 (Sus scrofa)
RAB31 GEFs exchange GTP for GDP on RAB31 (Bos taurus)
RAB31 GEFs exchange GTP for GDP on RAB31 (Rattus norvegicus)
RAB31 GEFs exchange GTP for GDP on RAB31 (Mus musculus)
RAB31 GEFs exchange GTP for GDP on RAB31 (Homo sapiens)
RAB9 GEFs exchange GTP for GDP on RAB9 (Dictyostelium discoideum)
RAB9 GEFs exchange GTP for GDP on RAB9 (Gallus gallus)
RAB9 GEFs exchange GTP for GDP on RAB9 (Xenopus tropicalis)
RAB9 GEFs exchange GTP for GDP on RAB9 (Sus scrofa)
RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)
RAB9 GEFs exchange GTP for GDP on RAB9 (Canis familiaris)
RAB9 GEFs exchange GTP for GDP on RAB9 (Rattus norvegicus)
RAB9 GEFs exchange GTP for GDP on RAB9 (Mus musculus)
RAB9 GEFs exchange GTP for GDP on RAB9 (Homo sapiens)
DENND5A,B exchange GTP for GDP on RAB39 (Caenorhabditis elegans)
DENND5A,B exchange GTP for GDP on RAB39 (Drosophila melanogaster)
DENND5A,B exchange GTP for GDP on RAB39 (Gallus gallus)
DENND5A,B exchange GTP for GDP on RAB39 (Sus scrofa)
DENND5A,B exchange GTP for GDP on RAB39 (Bos taurus)
DENND5A,B exchange GTP for GDP on RAB39 (Canis familiaris)
DENND5A,B exchange GTP for GDP on RAB39 (Rattus norvegicus)
DENND5A,B exchange GTP for GDP on RAB39 (Mus musculus)
DENND5A,B exchange GTP for GDP on RAB39 (Homo sapiens)
RAB3 GEFs exchange GTP for GDP on RAB3A (Saccharomyces cerevisiae)
RAB3 GEFs exchange GTP for GDP on RAB3A (Schizosaccharomyces pombe)
RAB3 GEFs exchange GTP for GDP on RAB3A (Caenorhabditis elegans)
RAB3 GEFs exchange GTP for GDP on RAB3A (Drosophila melanogaster)
RAB3 GEFs exchange GTP for GDP on RAB3A (Gallus gallus)
RAB3 GEFs exchange GTP for GDP on RAB3A (Xenopus tropicalis)
RAB3 GEFs exchange GTP for GDP on RAB3A (Sus scrofa)
RAB3 GEFs exchange GTP for GDP on RAB3A (Bos taurus)
RAB3 GEFs exchange GTP for GDP on RAB3A (Canis familiaris)
RAB3 GEFs exchange GTP for GDP on RAB3A (Rattus norvegicus)
RAB3 GEFs exchange GTP for GDP on RAB3A (Mus musculus)
RAB3 GEFs exchange GTP for GDP on RAB3A (Homo sapiens)
DENND6A,B exchange GTP for GDP on RAB14 (Dictyostelium discoideum)
DENND6A,B exchange GTP for GDP on RAB14 (Caenorhabditis elegans)
DENND6A,B exchange GTP for GDP on RAB14 (Drosophila melanogaster)
DENND6A,B exchange GTP for GDP on RAB14 (Gallus gallus)
DENND6A,B exchange GTP for GDP on RAB14 (Danio rerio)
DENND6A,B exchange GTP for GDP on RAB14 (Bos taurus)
DENND6A,B exchange GTP for GDP on RAB14 (Rattus norvegicus)
DENND6A,B exchange GTP for GDP on RAB14 (Mus musculus)
DENND6A,B exchange GTP for GDP on RAB14 (Homo sapiens)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Plasmodium falciparum)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Saccharomyces cerevisiae)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Dictyostelium discoideum)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Caenorhabditis elegans)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Drosophila melanogaster)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Gallus gallus)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Sus scrofa)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Bos taurus)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Canis familiaris)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Rattus norvegicus)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Mus musculus)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Homo sapiens)
DENND1s exchange GTP for GDP on RAB35 (Dictyostelium discoideum)
DENND1s exchange GTP for GDP on RAB35 (Caenorhabditis elegans)
DENND1s exchange GTP for GDP on RAB35 (Drosophila melanogaster)
DENND1s exchange GTP for GDP on RAB35 (Gallus gallus)
DENND1s exchange GTP for GDP on RAB35 (Xenopus tropicalis)
DENND1s exchange GTP for GDP on RAB35 (Sus scrofa)
DENND1s exchange GTP for GDP on RAB35 (Bos taurus)
DENND1s exchange GTP for GDP on RAB35 (Canis familiaris)
DENND1s exchange GTP for GDP on RAB35 (Rattus norvegicus)
DENND1s exchange GTP for GDP on RAB35 (Mus musculus)
DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Dictyostelium discoideum)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Caenorhabditis elegans)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Drosophila melanogaster)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Gallus gallus)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Sus scrofa)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Bos taurus)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Canis familiaris)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Rattus norvegicus)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Mus musculus)
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Homo sapiens)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Drosophila melanogaster)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Gallus gallus)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Danio rerio)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Sus scrofa)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Bos taurus)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Canis familiaris)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Rattus norvegicus)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Mus musculus)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Homo sapiens)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Saccharomyces cerevisiae)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Schizosaccharomyces pombe)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Dictyostelium discoideum)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Caenorhabditis elegans)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Drosophila melanogaster)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Gallus gallus)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Bos taurus)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Rattus norvegicus)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Mus musculus)
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Plasmodium falciparum)
TRAPPC complexes exchange GTP for GDP on RAB1 (Saccharomyces cerevisiae)
TRAPPC complexes exchange GTP for GDP on RAB1 (Schizosaccharomyces pombe)
TRAPPC complexes exchange GTP for GDP on RAB1 (Dictyostelium discoideum)
TRAPPC complexes exchange GTP for GDP on RAB1 (Caenorhabditis elegans)
TRAPPC complexes exchange GTP for GDP on RAB1 (Drosophila melanogaster)
TRAPPC complexes exchange GTP for GDP on RAB1 (Bos taurus)
TRAPPC complexes exchange GTP for GDP on RAB1 (Canis familiaris)
TRAPPC complexes exchange GTP for GDP on RAB1 (Rattus norvegicus)
TRAPPC complexes exchange GTP for GDP on RAB1 (Mus musculus)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
RAB21 GEFs exchange GTP for GDP on RAB21 (Dictyostelium discoideum)
RAB21 GEFs exchange GTP for GDP on RAB21 (Caenorhabditis elegans)
RAB21 GEFs exchange GTP for GDP on RAB21 (Drosophila melanogaster)
RAB21 GEFs exchange GTP for GDP on RAB21 (Gallus gallus)
RAB21 GEFs exchange GTP for GDP on RAB21 (Bos taurus)
RAB21 GEFs exchange GTP for GDP on RAB21 (Rattus norvegicus)
RAB21 GEFs exchange GTP for GDP on RAB21 (Mus musculus)
RAB21 GEFs exchange GTP for GDP on RAB21 (Homo sapiens)
DENND3 exchanges GTP for GDP on RAB12 (Schizosaccharomyces pombe)
DENND3 exchanges GTP for GDP on RAB12 (Dictyostelium discoideum)
DENND3 exchanges GTP for GDP on RAB12 (Gallus gallus)
DENND3 exchanges GTP for GDP on RAB12 (Sus scrofa)
DENND3 exchanges GTP for GDP on RAB12 (Bos taurus)
DENND3 exchanges GTP for GDP on RAB12 (Canis familiaris)
DENND3 exchanges GTP for GDP on RAB12 (Rattus norvegicus)
DENND3 exchanges GTP for GDP on RAB12 (Mus musculus)
DENND3 exchanges GTP for GDP on RAB12 (Homo sapiens)
RAB13 GEFs exchange GTP for GDP on RAB13 (Dictyostelium discoideum)
RAB13 GEFs exchange GTP for GDP on RAB13 (Caenorhabditis elegans)
RAB13 GEFs exchange GTP for GDP on RAB13 (Drosophila melanogaster)
RAB13 GEFs exchange GTP for GDP on RAB13 (Xenopus tropicalis)
RAB13 GEFs exchange GTP for GDP on RAB13 (Sus scrofa)
RAB13 GEFs exchange GTP for GDP on RAB13 (Bos taurus)
RAB13 GEFs exchange GTP for GDP on RAB13 (Canis familiaris)
RAB13 GEFs exchange GTP for GDP on RAB13 (Rattus norvegicus)
RAB13 GEFs exchange GTP for GDP on RAB13 (Mus musculus)
RAB13 GEFs exchange GTP for GDP on RAB13 (Homo sapiens)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)
RHOT1 GEFs activate RHOT1 (Homo sapiens)
Vimar activates Miro (Drosophila melanogaster)
RHOT2 GEFs activate RHOT2 (Homo sapiens)
RHOA GEFs activate RHOA (Caenorhabditis elegans)
RHOA GEFs activate RHOA (Drosophila melanogaster)
RHOA GEFs activate RHOA (Gallus gallus)
RHOA GEFs activate RHOA (Xenopus tropicalis)
RHOA GEFs activate RHOA (Danio rerio)
RHOA GEFs activate RHOA (Sus scrofa)
RHOA GEFs activate RHOA (Bos taurus)
RHOA GEFs activate RHOA (Canis familiaris)
RHOA GEFs activate RHOA (Rattus norvegicus)
RHOA GEFs activate RHOA (Mus musculus)
RHOA GEFs activate RHOA (Homo sapiens)
RHOC GEFs activate RHOC (Gallus gallus)
RHOC GEFs activate RHOC (Sus scrofa)
RHOC GEFs activate RHOC (Bos taurus)
RHOC GEFs activate RHOC (Canis familiaris)
RHOC GEFs activate RHOC (Mus musculus)
RHOC GEFs activate RHOC (Homo sapiens)
RHOV binds GTP (Saccharomyces cerevisiae)
RHOV binds GTP (Schizosaccharomyces pombe)
RHOV binds GTP (Dictyostelium discoideum)
RHOV binds GTP (Caenorhabditis elegans)
RHOV binds GTP (Drosophila melanogaster)
RHOV binds GTP (Gallus gallus)
RHOV binds GTP (Xenopus tropicalis)
RHOV binds GTP (Danio rerio)
RHOV binds GTP (Sus scrofa)
RHOV binds GTP (Bos taurus)
RHOV binds GTP (Canis familiaris)
RHOV binds GTP (Rattus norvegicus)
RHOV binds GTP (Mus musculus)
RHOV binds GTP (Homo sapiens)
CDC42 GEFs activate CDC42 (Saccharomyces cerevisiae)
CDC42 GEFs activate CDC42 (Schizosaccharomyces pombe)
CDC42 GEFs activate CDC42 (Dictyostelium discoideum)
CDC42 GEFs activate CDC42 (Caenorhabditis elegans)
CDC42 GEFs activate CDC42 (Drosophila melanogaster)
CDC42 GEFs activate CDC42 (Gallus gallus)
CDC42 GEFs activate CDC42 (Xenopus tropicalis)
CDC42 GEFs activate CDC42 (Danio rerio)
CDC42 GEFs activate CDC42 (Sus scrofa)
CDC42 GEFs activate CDC42 (Bos taurus)
CDC42 GEFs activate CDC42 (Canis familiaris)
CDC42 GEFs activate CDC42 (Rattus norvegicus)
CDC42 GEFs activate CDC42 (Mus musculus)
CDC42 GEFs activate CDC42 (Homo sapiens)
RAC2 GEFs activate RAC2 (Dictyostelium discoideum)
RAC2 GEFs activate RAC2 (Caenorhabditis elegans)
RAC2 GEFs activate RAC2 (Drosophila melanogaster)
RAC2 GEFs activate RAC2 (Gallus gallus)
RAC2 GEFs activate RAC2 (Xenopus tropicalis)
RAC2 GEFs activate RAC2 (Danio rerio)
RAC2 GEFs activate RAC2 (Sus scrofa)
RAC2 GEFs activate RAC2 (Bos taurus)
RAC2 GEFs activate RAC2 (Canis familiaris)
RAC2 GEFs activate RAC2 (Rattus norvegicus)
RAC2 GEFs activate RAC2 (Mus musculus)
RAC2 GEFs activate RAC2 (Homo sapiens)
RHOD auto-activates (Saccharomyces cerevisiae)
RHOD auto-activates (Schizosaccharomyces pombe)
RHOD auto-activates (Caenorhabditis elegans)
RHOD auto-activates (Drosophila melanogaster)
RHOD auto-activates (Gallus gallus)
RHOD auto-activates (Xenopus tropicalis)
RHOD auto-activates (Danio rerio)
RHOD auto-activates (Sus scrofa)
RHOD auto-activates (Bos taurus)
RHOD auto-activates (Canis familiaris)
RHOD auto-activates (Rattus norvegicus)
RHOD auto-activates (Mus musculus)
RHOD auto-activates (Homo sapiens)
RAC1 GEFs activate RAC1 (Dictyostelium discoideum)
RAC1 GEFs activate RAC1 (Caenorhabditis elegans)
RAC1 GEFs activate RAC1 (Drosophila melanogaster)
RAC1 GEFs activate RAC1 (Gallus gallus)
RAC1 GEFs activate RAC1 (Xenopus tropicalis)
RAC1 GEFs activate RAC1 (Danio rerio)
RAC1 GEFs activate RAC1 (Sus scrofa)
RAC1 GEFs activate RAC1 (Bos taurus)
RAC1 GEFs activate RAC1 (Canis familiaris)
RAC1 GEFs activate RAC1 (Rattus norvegicus)
RAC1 GEFs activate RAC1 (Mus musculus)
RAC1 GEFs activate RAC1 (Homo sapiens)
RHOF auto-activates (Saccharomyces cerevisiae)
RHOF auto-activates (Schizosaccharomyces pombe)
RHOF auto-activates (Caenorhabditis elegans)
RHOF auto-activates (Drosophila melanogaster)
RHOF auto-activates (Gallus gallus)
RHOF auto-activates (Xenopus tropicalis)
RHOF auto-activates (Danio rerio)
RHOF auto-activates (Sus scrofa)
RHOF auto-activates (Bos taurus)
RHOF auto-activates (Canis familiaris)
RHOF auto-activates (Rattus norvegicus)
RHOF auto-activates (Mus musculus)
RHOF auto-activates (Homo sapiens)
RHOB GEFs activate RHOB (Caenorhabditis elegans)
RHOB GEFs activate RHOB (Drosophila melanogaster)
RHOB GEFs activate RHOB (Gallus gallus)
RHOB GEFs activate RHOB (Xenopus tropicalis)
RHOB GEFs activate RHOB (Sus scrofa)
RHOB GEFs activate RHOB (Canis familiaris)
RHOB GEFs activate RHOB (Rattus norvegicus)
RHOB GEFs activate RHOB (Mus musculus)
RHOB GEFs activate RHOB (Homo sapiens)
RHOG GEFs activate RHOG (Dictyostelium discoideum)
RHOG GEFs activate RHOG (Caenorhabditis elegans)
RHOG GEFs activate RHOG (Drosophila melanogaster)
RHOG GEFs activate RHOG (Gallus gallus)
RHOG GEFs activate RHOG (Xenopus tropicalis)
RHOG GEFs activate RHOG (Danio rerio)
RHOG GEFs activate RHOG (Sus scrofa)
RHOG GEFs activate RHOG (Bos taurus)
RHOG GEFs activate RHOG (Canis familiaris)
RHOG GEFs activate RHOG (Rattus norvegicus)
RHOG GEFs activate RHOG (Mus musculus)
RHOG GEFs activate RHOG (Homo sapiens)
RHOJ GEFs activate RHOJ (Dictyostelium discoideum)
RHOJ GEFs activate RHOJ (Caenorhabditis elegans)
RHOJ GEFs activate RHOJ (Drosophila melanogaster)
RHOJ GEFs activate RHOJ (Gallus gallus)
RHOJ GEFs activate RHOJ (Xenopus tropicalis)
RHOJ GEFs activate RHOJ (Sus scrofa)
RHOJ GEFs activate RHOJ (Bos taurus)
RHOJ GEFs activate RHOJ (Canis familiaris)
RHOJ GEFs activate RHOJ (Rattus norvegicus)
RHOJ GEFs activate RHOJ (Mus musculus)
RHOJ GEFs activate RHOJ (Homo sapiens)
RAC3 GEFs activate RAC3 (Dictyostelium discoideum)
RAC3 GEFs activate RAC3 (Caenorhabditis elegans)
RAC3 GEFs activate RAC3 (Drosophila melanogaster)
RAC3 GEFs activate RAC3 (Gallus gallus)
RAC3 GEFs activate RAC3 (Xenopus tropicalis)
RAC3 GEFs activate RAC3 (Danio rerio)
RAC3 GEFs activate RAC3 (Sus scrofa)
RAC3 GEFs activate RAC3 (Bos taurus)
RAC3 GEFs activate RAC3 (Canis familiaris)
RAC3 GEFs activate RAC3 (Mus musculus)
RAC3 GEFs activate RAC3 (Homo sapiens)
RHOU auto-activates (Saccharomyces cerevisiae)
RHOU auto-activates (Schizosaccharomyces pombe)
RHOU auto-activates (Dictyostelium discoideum)
RHOU auto-activates (Caenorhabditis elegans)
RHOU auto-activates (Drosophila melanogaster)
RHOU auto-activates (Gallus gallus)
RHOU auto-activates (Xenopus tropicalis)
RHOU auto-activates (Danio rerio)
RHOU auto-activates (Sus scrofa)
RHOU auto-activates (Bos taurus)
RHOU auto-activates (Canis familiaris)
RHOU auto-activates (Rattus norvegicus)
RHOU auto-activates (Mus musculus)
RHOU auto-activates (Homo sapiens)
RHOQ GEFs activate RHOQ (Saccharomyces cerevisiae)
RHOQ GEFs activate RHOQ (Schizosaccharomyces pombe)
RHOQ GEFs activate RHOQ (Dictyostelium discoideum)
RHOQ GEFs activate RHOQ (Caenorhabditis elegans)
RHOQ GEFs activate RHOQ (Drosophila melanogaster)
RHOQ GEFs activate RHOQ (Gallus gallus)
RHOQ GEFs activate RHOQ (Xenopus tropicalis)
RHOQ GEFs activate RHOQ (Sus scrofa)
RHOQ GEFs activate RHOQ (Bos taurus)
RHOQ GEFs activate RHOQ (Canis familiaris)
RHOQ GEFs activate RHOQ (Rattus norvegicus)
RHOQ GEFs activate RHOQ (Mus musculus)
RHOQ GEFs activate RHOQ (Homo sapiens)
Gnal exchanges GDP for GTP (Rattus norvegicus)
GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 (Homo sapiens)
GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
Gnat3 exchanges GDP for GTP in Gnat3:GNB5:GNG3 (Bos taurus)
GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
Gnat3 exchanges GDP for GTP in Gnat3:Gnb1:Gng13 (Mus musculus)
GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Caenorhabditis elegans)
RAB3IP stimulates nucleotide exchange on RAB8A (Drosophila melanogaster)
RAB3IP stimulates nucleotide exchange on RAB8A (Gallus gallus)
RAB3IP stimulates nucleotide exchange on RAB8A (Xenopus tropicalis)
RAB3IP stimulates nucleotide exchange on RAB8A (Danio rerio)
RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
GBF1 stimulates nucleotide exchange on ARF4 (Plasmodium falciparum)
GBF1 stimulates nucleotide exchange on ARF4 (Saccharomyces cerevisiae)
GBF1 stimulates nucleotide exchange on ARF4 (Schizosaccharomyces pombe)
GBF1 stimulates nucleotide exchange on ARF4 (Dictyostelium discoideum)
GBF1 stimulates nucleotide exchange on ARF4 (Drosophila melanogaster)
GBF1 stimulates nucleotide exchange on ARF4 (Gallus gallus)
GBF1 stimulates nucleotide exchange on ARF4 (Sus scrofa)
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
GBF1 stimulates nucleotide exchange on ARF4 (Canis familiaris)
GBF1 stimulates nucleotide exchange on ARF4 (Rattus norvegicus)
GBF1 stimulates nucleotide exchange on ARF4 (Mus musculus)
GBF1 stimulates nucleotide exchange on ARF4 (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Gallus gallus)
RAB3IP stimulates nucleotide exchange on RAB8A (Xenopus tropicalis)
RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
APS is phosphorylated to PAPS (Mycobacterium tuberculosis)
Translocation of TGN-lysosome vesicle to lysosome (Gallus gallus)
Translocation of TGN-lysosome vesicle to lysosome (Xenopus tropicalis)
Translocation of TGN-lysosome vesicle to lysosome (Danio rerio)
Translocation of TGN-lysosome vesicle to lysosome (Sus scrofa)
Translocation of TGN-lysosome vesicle to lysosome (Bos taurus)
Translocation of TGN-lysosome vesicle to lysosome (Canis familiaris)
Translocation of TGN-lysosome vesicle to lysosome (Rattus norvegicus)
Translocation of TGN-lysosome vesicle to lysosome (Mus musculus)
Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)
Internalization of MHC II:Ii clathrin coated vesicle (Gallus gallus)
Internalization of MHC II:Ii clathrin coated vesicle (Sus scrofa)
Internalization of MHC II:Ii clathrin coated vesicle (Bos taurus)
Internalization of MHC II:Ii clathrin coated vesicle (Canis familiaris)
Internalization of MHC II:Ii clathrin coated vesicle (Rattus norvegicus)
Internalization of MHC II:Ii clathrin coated vesicle (Mus musculus)
Internalization of MHC II:Ii clathrin coated vesicle (Homo sapiens)
Csf1r-associated Sos1 mediates exchange of GTP for GDP bound to Ras (Mus musculus)
CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)
VAV1 is a GEF for Rho/Rac family GTPases (Caenorhabditis elegans)
VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)
VAV1 is a GEF for Rho/Rac family GTPases (Xenopus tropicalis)
VAV1 is a GEF for Rho/Rac family GTPases (Sus scrofa)
VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)
VAV1 is a GEF for Rho/Rac family GTPases (Canis familiaris)
VAV1 is a GEF for Rho/Rac family GTPases (Rattus norvegicus)
VAV1 is a GEF for Rho/Rac family GTPases (Mus musculus)
VAV1 is a GEF for Rho/Rac family GTPases (Homo sapiens)
Activation of Rap1 by membrane-associated GEFs (Saccharomyces cerevisiae)
Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)
Activation of Rap1 by membrane-associated GEFs (Gallus gallus)
Activation of Rap1 by membrane-associated GEFs (Xenopus tropicalis)
Activation of Rap1 by membrane-associated GEFs (Sus scrofa)
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
Activation of Rap1 by membrane-associated GEFs (Canis familiaris)
Activation of Rap1 by membrane-associated GEFs (Rattus norvegicus)
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
Activation of Rap1 by membrane-associated GEFs (Homo sapiens)
Activation of Rap1 by cytosolic GEFs (Saccharomyces cerevisiae)
Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Gallus gallus)
Activation of Rap1 by cytosolic GEFs (Xenopus tropicalis)
Activation of Rap1 by cytosolic GEFs (Sus scrofa)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Canis familiaris)
Activation of Rap1 by cytosolic GEFs (Rattus norvegicus)
Activation of Rap1 by cytosolic GEFs (Mus musculus)
Activation of Rap1 by cytosolic GEFs (Homo sapiens)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Caenorhabditis elegans)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Drosophila melanogaster)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Gallus gallus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Xenopus tropicalis)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Sus scrofa)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Bos taurus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Canis familiaris)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Rattus norvegicus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Mus musculus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Homo sapiens)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Caenorhabditis elegans)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Drosophila melanogaster)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Xenopus tropicalis)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Danio rerio)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Sus scrofa)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Canis familiaris)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Rattus norvegicus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Mus musculus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Homo sapiens)
RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)
RAP1A exchanges GDP for GTP (Dictyostelium discoideum)
RAP1A exchanges GDP for GTP (Caenorhabditis elegans)
RAP1A exchanges GDP for GTP (Drosophila melanogaster)
RAP1A exchanges GDP for GTP (Gallus gallus)
RAP1A exchanges GDP for GTP (Xenopus tropicalis)
RAP1A exchanges GDP for GTP (Danio rerio)
RAP1A exchanges GDP for GTP (Sus scrofa)
RAP1A exchanges GDP for GTP (Bos taurus)
RAP1A exchanges GDP for GTP (Canis familiaris)
RAP1A exchanges GDP for GTP (Rattus norvegicus)
RAP1A exchanges GDP for GTP (Mus musculus)
RAP1A exchanges GDP for GTP (Homo sapiens)
MII catalyses GDP/GTP exchange on Gt (Bos taurus)
MII catalyses GDP/GTP exchange on Gt (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII) (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII) (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)
SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers (Homo sapiens)
SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1 (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 (Homo sapiens)
RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants (Homo sapiens)
FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS (Homo sapiens)
p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)
Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
Activation of CDC42 by intersectin-1 (Mus musculus)
ITSN1 exchanges GTP for GDP on CDC42, activating it (Homo sapiens)
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
VAV exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)
VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Danio rerio)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Bos taurus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
Activation of Rac1 by VAV2 (Caenorhabditis elegans)
Activation of Rac1 by VAV2 (Drosophila melanogaster)
Activation of Rac1 by VAV2 (Gallus gallus)
Activation of Rac1 by VAV2 (Sus scrofa)
Activation of Rac1 by VAV2 (Bos taurus)
Activation of Rac1 by VAV2 (Canis familiaris)
Activation of Rac1 by VAV2 (Rattus norvegicus)
Activation of Rac1 by VAV2 (Mus musculus)
Activation of Rac1 by VAV2 (Homo sapiens)
Formation of clathrin coated vesicle (Caenorhabditis elegans)
Formation of clathrin coated vesicle (Drosophila melanogaster)
Formation of clathrin coated vesicle (Gallus gallus)
Formation of clathrin coated vesicle (Sus scrofa)
Formation of clathrin coated vesicle (Bos taurus)
Formation of clathrin coated vesicle (Canis familiaris)
Formation of clathrin coated vesicle (Rattus norvegicus)
Formation of clathrin coated vesicle (Mus musculus)
Formation of clathrin coated vesicle (Homo sapiens)
Activation of Rac by Sos (Drosophila melanogaster)
Activation of RAC1 by SOS (Homo sapiens)
RRAGA,B exchanges GDP for GTP (Schizosaccharomyces pombe)
RRAGA,B exchanges GDP for GTP (Dictyostelium discoideum)
RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
RRAGA,B exchanges GDP for GTP (Drosophila melanogaster)
RRAGA,B exchanges GDP for GTP (Gallus gallus)
RRAGA,B exchanges GDP for GTP (Xenopus tropicalis)
RRAGA,B exchanges GDP for GTP (Danio rerio)
RRAGA,B exchanges GDP for GTP (Sus scrofa)
RRAGA,B exchanges GDP for GTP (Bos taurus)
RRAGA,B exchanges GDP for GTP (Canis familiaris)
RRAGA,B exchanges GDP for GTP (Rattus norvegicus)
RRAGA,B exchanges GDP for GTP (Mus musculus)
RRAGA,B exchanges GDP for GTP (Homo sapiens)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Ntrk2 activates Ras signaling through Shc1 (Rattus norvegicus)
NTRK2 activates RAS signaling through SHC1 (Homo sapiens)
DOCK3 activates RAC1 (Gallus gallus)
DOCK3 activates RAC1 (Xenopus tropicalis)
DOCK3 activates RAC1 (Sus scrofa)
DOCK3 activates RAC1 (Bos taurus)
DOCK3 activates RAC1 (Canis familiaris)
DOCK3 activates RAC1 (Rattus norvegicus)
DOCK3 activates RAC1 (Mus musculus)
DOCK3 activates RAC1 (Homo sapiens)
Ntrk2 and Cdk5 promote activation of Rac1 by Tiam1 (Homo sapiens)
NTRK2 and CDK5 promote activation of RAC1 by TIAM1 (Homo sapiens)
Ntrk2 activates Ras signaling through Frs2 (Homo sapiens)
NTRK2 activates RAS signaling through FRS2 (Homo sapiens)
Ntrk3 activates Ras (Rattus norvegicus)
NTRK3 activates RAS through SHC1 (Homo sapiens)
CD209 activate GTPase RAS (Homo sapiens)
eIF2 activation (Plasmodium falciparum)
eIF2 activation (Saccharomyces cerevisiae)
eIF2 activation (Schizosaccharomyces pombe)
eIF2 activation (Dictyostelium discoideum)
eIF2 activation (Caenorhabditis elegans)
eIF2 activation (Drosophila melanogaster)
eIF2 activation (Gallus gallus)
eIF2 activation (Danio rerio)
eIF2 activation (Sus scrofa)
eIF2 activation (Bos taurus)
eIF2 activation (Canis familiaris)
eIF2 activation (Rattus norvegicus)
eIF2 activation (Homo sapiens)
eIF2 activation (Mus musculus)
Nucleotide exchange on RAB1 (Plasmodium falciparum)
Nucleotide exchange on RAB1 (Saccharomyces cerevisiae)
Nucleotide exchange on RAB1 (Schizosaccharomyces pombe)
Nucleotide exchange on RAB1 (Dictyostelium discoideum)
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
Nucleotide exchange on RAB1 (Drosophila melanogaster)
Nucleotide exchange on RAB1 (Gallus gallus)
Nucleotide exchange on RAB1 (Xenopus tropicalis)
Nucleotide exchange on RAB1 (Danio rerio)
Nucleotide exchange on RAB1 (Sus scrofa)
Nucleotide exchange on RAB1 (Bos taurus)
Nucleotide exchange on RAB1 (Canis familiaris)
Nucleotide exchange on RAB1 (Rattus norvegicus)
Nucleotide exchange on RAB1 (Mus musculus)
Nucleotide exchange on RAB1 (Homo sapiens)
SAR1 Activation And Membrane Binding (Danio rerio)
SAR1 Activation And Membrane Binding (Plasmodium falciparum)
SAR1 Activation And Membrane Binding (Saccharomyces cerevisiae)
SAR1 Activation And Membrane Binding (Schizosaccharomyces pombe)
SAR1 Activation And Membrane Binding (Dictyostelium discoideum)
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
SAR1 Activation And Membrane Binding (Drosophila melanogaster)
SAR1 Activation And Membrane Binding (Xenopus tropicalis)
SAR1 Activation And Membrane Binding (Sus scrofa)
SAR1 Activation And Membrane Binding (Bos taurus)
SAR1 Activation And Membrane Binding (Canis familiaris)
SAR1 Activation And Membrane Binding (Rattus norvegicus)
SAR1 Activation And Membrane Binding (Mus musculus)
SAR1 Activation And Membrane Binding (Homo sapiens)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Xenopus tropicalis)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Danio rerio)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Sus scrofa)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Rattus norvegicus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Mus musculus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Homo sapiens)
Gq activation by TP receptor (Caenorhabditis elegans)
Gq activation by TP receptor (Drosophila melanogaster)
Gq activation by TP receptor (Gallus gallus)
Gq activation by TP receptor (Xenopus tropicalis)
Gq activation by TP receptor (Danio rerio)
Gq activation by TP receptor (Sus scrofa)
Gq activation by TP receptor (Bos taurus)
Gq activation by TP receptor (Canis familiaris)
Gq activation by TP receptor (Rattus norvegicus)
Gq activation by TP receptor (Mus musculus)
Gq activation by TP receptor (Homo sapiens)
p115-RhoGEF activation of RHOA (Caenorhabditis elegans)
p115-RhoGEF activation of RHOA (Drosophila melanogaster)
p115-RhoGEF activation of RHOA (Sus scrofa)
p115-RhoGEF activation of RHOA (Bos taurus)
p115-RhoGEF activation of RHOA (Canis familiaris)
p115-RhoGEF activation of RHOA (Rattus norvegicus)
p115-RhoGEF activation of RHOA (Mus musculus)
p115-RhoGEF activation of RHOA (Homo sapiens)
Opsins act as GEFs for G alpha-t (Caenorhabditis elegans)
Opsins act as GEFs for G alpha-t (Gallus gallus)
Opsins act as GEFs for G alpha-t (Xenopus tropicalis)
Opsins act as GEFs for G alpha-t (Danio rerio)
Opsins act as GEFs for G alpha-t (Sus scrofa)
Opsins act as GEFs for G alpha-t (Bos taurus)
Opsins act as GEFs for G alpha-t (Canis familiaris)
Opsins act as GEFs for G alpha-t (Rattus norvegicus)
Opsins act as GEFs for G alpha-t (Mus musculus)
Opsins act as GEFs for G alpha-t (Homo sapiens)
The receptor:G-protein complex releases GDP (Caenorhabditis elegans)
The receptor:G-protein complex releases GDP (Drosophila melanogaster)
The receptor:G-protein complex releases GDP (Gallus gallus)
The receptor:G-protein complex releases GDP (Xenopus tropicalis)
The receptor:G-protein complex releases GDP (Sus scrofa)
The receptor:G-protein complex releases GDP (Bos taurus)
The receptor:G-protein complex releases GDP (Canis familiaris)
The receptor:G-protein complex releases GDP (Rattus norvegicus)
The receptor:G-protein complex releases GDP (Mus musculus)
The receptor:G-protein complex releases GDP (Homo sapiens)
Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11 (Saccharomyces cerevisiae)
Addition of a third mannose to the N-glycan precursor by Alg2 (Saccharomyces cerevisiae)
Addition of a second mannose to the N-glycan precursor by ALG2 (Saccharomyces cerevisiae)
Addition of a second mannose to the N-glycan precursor by ALG2 (Schizosaccharomyces pombe)
Addition of a second mannose to the N-glycan precursor by ALG2 (Dictyostelium discoideum)
Addition of a second mannose to the N-glycan precursor by ALG2 (Caenorhabditis elegans)
Addition of a second mannose to the N-glycan precursor by ALG2 (Drosophila melanogaster)
Addition of a second mannose to the N-glycan precursor by ALG2 (Gallus gallus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Xenopus tropicalis)
Addition of a second mannose to the N-glycan precursor by ALG2 (Sus scrofa)
Addition of a second mannose to the N-glycan precursor by ALG2 (Bos taurus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Canis familiaris)
Addition of a second mannose to the N-glycan precursor by ALG2 (Rattus norvegicus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Mus musculus)
Addition of the first mannose to the N-glycan precursor by ALG1 (Saccharomyces cerevisiae)
Addition of the first mannose to the N-glycan precursor by ALG1 (Schizosaccharomyces pombe)
Addition of the first mannose to the N-glycan precursor by ALG1 (Dictyostelium discoideum)
Addition of the first mannose to the N-glycan precursor by ALG1 (Caenorhabditis elegans)
Addition of the first mannose to the N-glycan precursor by ALG1 (Drosophila melanogaster)
Addition of the first mannose to the N-glycan precursor by ALG1 (Gallus gallus)
Addition of the first mannose to the N-glycan precursor by ALG1 (Danio rerio)
Addition of the first mannose to the N-glycan precursor by ALG1 (Sus scrofa)
Addition of the first mannose to the N-glycan precursor by ALG1 (Bos taurus)
Addition of the first mannose to the N-glycan precursor by ALG1 (Canis familiaris)
Addition of the first mannose to the N-glycan precursor by ALG1 (Rattus norvegicus)
Addition of the first mannose to the N-glycan precursor by ALG1 (Mus musculus)
Addition of the first mannose to the N-glycan precursor by ALG1 (Homo sapiens)
Addition of a second mannose to the N-glycan precursor by ALG2 (Homo sapiens)
Addition of a third mannose to the N-glycan precursor by ALG2 (Homo sapiens)
ALG11 transfers the fourth and fifth Man to the N-glycan precursor (Homo sapiens)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Plasmodium falciparum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Saccharomyces cerevisiae)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Schizosaccharomyces pombe)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Drosophila melanogaster)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Gallus gallus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Xenopus tropicalis)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Danio rerio)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Sus scrofa)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Mus musculus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Homo sapiens)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Rattus norvegicus)
RCC1 stimulates GDP to GTP exchange on RAN (Saccharomyces cerevisiae)
RCC1 stimulates GDP to GTP exchange on RAN (Schizosaccharomyces pombe)
RCC1 stimulates GDP to GTP exchange on RAN (Dictyostelium discoideum)
RCC1 stimulates GDP to GTP exchange on RAN (Caenorhabditis elegans)
RCC1 stimulates GDP to GTP exchange on RAN (Drosophila melanogaster)
RCC1 stimulates GDP to GTP exchange on RAN (Gallus gallus)
RCC1 stimulates GDP to GTP exchange on RAN (Xenopus tropicalis)
RCC1 stimulates GDP to GTP exchange on RAN (Danio rerio)
RCC1 stimulates GDP to GTP exchange on RAN (Sus scrofa)
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
RCC1 stimulates GDP to GTP exchange on RAN (Canis familiaris)
RCC1 stimulates GDP to GTP exchange on RAN (Rattus norvegicus)
RCC1 stimulates GDP to GTP exchange on RAN (Mus musculus)
RCC1 stimulates GDP to GTP exchange on RAN (Homo sapiens)
RCC1 stimulates GDP to GTP exchange on RAN (Plasmodium falciparum)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Caenorhabditis elegans)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Gallus gallus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Xenopus tropicalis)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Danio rerio)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Sus scrofa)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Canis familiaris)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Rattus norvegicus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Mus musculus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Homo sapiens)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Gallus gallus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Xenopus tropicalis)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Canis familiaris)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Rattus norvegicus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Mus musculus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Homo sapiens)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
DOCK7 activates RAC1 (Caenorhabditis elegans)
DOCK7 activates RAC1 (Xenopus tropicalis)
DOCK7 activates RAC1 (Sus scrofa)
DOCK7 activates RAC1 (Bos taurus)
DOCK7 activates RAC1 (Canis familiaris)
DOCK7 activates RAC1 (Rattus norvegicus)
DOCK7 activates RAC1 (Mus musculus)
DOCK7 activates RAC1 (Homo sapiens)
DOCK7 activates RAC1 (Gallus gallus)
RAPGEF1 activates RAP1 (Caenorhabditis elegans)
RAPGEF1 activates RAP1 (Xenopus tropicalis)
RAPGEF1 activates RAP1 (Sus scrofa)
RAPGEF1 activates RAP1 (Bos taurus)
RAPGEF1 activates RAP1 (Canis familiaris)
RAPGEF1 activates RAP1 (Rattus norvegicus)
RAPGEF1 activates RAP1 (Mus musculus)
RAPGEF1 activates RAP1 (Homo sapiens)
RAPGEF1 activates RAP1 (Gallus gallus)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Gallus gallus)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Xenopus tropicalis)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Sus scrofa)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Canis familiaris)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Mus musculus)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Homo sapiens)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Caenorhabditis elegans)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Gallus gallus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Sus scrofa)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Canis familiaris)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Rattus norvegicus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Mus musculus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Homo sapiens)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Xenopus tropicalis)
Endocytosis of clathrin-coated vesicle (Rattus norvegicus)
Endocytosis (internalization) of clathrin-coated vesicle (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Dictyostelium discoideum)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Drosophila melanogaster)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Gallus gallus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Xenopus tropicalis)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Danio rerio)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Canis familiaris)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Rattus norvegicus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Sus scrofa)
Rit is activated (Rattus norvegicus)
RIT/RIN are activated (Homo sapiens)
C3G stimulates nucleotide exchange on Rap1 (Gallus gallus)
C3G stimulates nucleotide exchange on Rap1 (Xenopus tropicalis)
C3G stimulates nucleotide exchange on Rap1 (Danio rerio)
C3G stimulates nucleotide exchange on Rap1 (Bos taurus)
C3G stimulates nucleotide exchange on Rap1 (Canis familiaris)
C3G stimulates nucleotide exchange on Rap1 (Rattus norvegicus)
C3G stimulates nucleotide exchange on Rap1 (Mus musculus)
C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
C3G stimulates nucleotide exchange on Rap1 (Sus scrofa)
GRB2-1:SOS1:p-Y-SHC mediated nucleotide exchange of RAS (Homo sapiens)
Guanine nucleotide exchange on Ral (Rattus norvegicus)
Guanine nucleotide exchange on RAL (Homo sapiens)
VEGF induces CDC42 activation by unknown mechanism (Homo sapiens)
GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)
Activation of RAC1 (Caenorhabditis elegans)
Activation of RAC1 (Drosophila melanogaster)
Activation of RAC1 (Xenopus tropicalis)
Activation of RAC1 (Sus scrofa)
Activation of RAC1 (Bos taurus)
Activation of RAC1 (Canis familiaris)
Activation of RAC1 (Rattus norvegicus)
Activation of RAC1 (Mus musculus)
Activation of RAC1 (Homo sapiens)
Activation of RAS by p-KIT bound SOS1 (Caenorhabditis elegans)
Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)
Activation of RAS by p-KIT bound SOS1 (Gallus gallus)
Activation of RAS by p-KIT bound SOS1 (Xenopus tropicalis)
Activation of RAS by p-KIT bound SOS1 (Sus scrofa)
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
Activation of RAS by p-KIT bound SOS1 (Canis familiaris)
Activation of RAS by p-KIT bound SOS1 (Rattus norvegicus)
Activation of RAS by p-KIT bound SOS1 (Mus musculus)
Activation of RAS by p-KIT bound SOS1 (Homo sapiens)
Activation of RAS by p-KIT bound SOS1 (Danio rerio)
p-S516-Arhgef7 activates Rac1 (Rattus norvegicus)
p-S516-ARHGEF7 activates RAC1 (Homo sapiens)
Rasgrf1 promotes activation of HRAS (Rattus norvegicus)
NMDA-activated RASGRF1 activates RAS (Homo sapiens)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Gallus gallus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Xenopus tropicalis)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Danio rerio)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Sus scrofa)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Rattus norvegicus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Mus musculus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Homo sapiens)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Canis familiaris)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Gallus gallus)
SOS mediated nucleotide exchange of RAS (SHC) (Xenopus tropicalis)
SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
SOS mediated nucleotide exchange of RAS (SHC) (Mus musculus)
SOS mediated nucleotide exchange of RAS (SHC) (Homo sapiens)
SOS mediated nucleotide exchange of RAS (SHC) (Rattus norvegicus)
Activation of RAC1 by VAV2/3 (Drosophila melanogaster)
Activation of RAC1 by VAV2/3 (Gallus gallus)
Activation of RAC1 by VAV2/3 (Xenopus tropicalis)
Activation of RAC1 by VAV2/3 (Sus scrofa)
Activation of RAC1 by VAV2/3 (Bos taurus)
Activation of RAC1 by VAV2/3 (Canis familiaris)
Activation of RAC1 by VAV2/3 (Mus musculus)
Activation of RAC1 by VAV2/3 (Homo sapiens)
Activation of RAC1 by VAV2/3 (Rattus norvegicus)
Grb2:Sos2:p-Y-Irs1 mediated nucleotide exchange of p21 Ras (IRS) (Rattus norvegicus)
GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS (Homo sapiens)
SOS mediated nucleotide exchange of RAS (SHC) (Rattus norvegicus)
GRB2-1:SOS1:p-3Y-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Homo sapiens)
Activation of Rac1 by FARP2 (Mus musculus)
Activation of Rac1 by FARP2 (Homo sapiens)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Caenorhabditis elegans)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Drosophila melanogaster)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Gallus gallus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Xenopus tropicalis)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Sus scrofa)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Canis familiaris)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Rattus norvegicus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Mus musculus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Homo sapiens)
Activation of RAC1 by VAV (Gallus gallus)
Activation of RAC1 by VAV (Sus scrofa)
Activation of RAC1 by VAV (Bos taurus)
Activation of RAC1 by VAV (Canis familiaris)
Activation of RAC1 by VAV (Rattus norvegicus)
Activation of RAC1 by VAV (Mus musculus)
Activation of RAC1 by VAV (Homo sapiens)
Activation of RAC1 by CRKII:DOCK180:ELMO (Gallus gallus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Sus scrofa)
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Canis familiaris)
Activation of RAC1 by CRKII:DOCK180:ELMO (Rattus norvegicus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Mus musculus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)
DOCK180 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
VAV exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)
VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Drosophila melanogaster)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Sus scrofa)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Canis familiaris)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Rattus norvegicus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Mus musculus)
NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)
NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)
NGEF exchanges GTP for GDP on RHOA (Gallus gallus)
NGEF exchanges GTP for GDP on RHOA (Xenopus tropicalis)
NGEF exchanges GTP for GDP on RHOA (Danio rerio)
NGEF exchanges GTP for GDP on RHOA (Sus scrofa)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Canis familiaris)
NGEF exchanges GTP for GDP on RHOA (Rattus norvegicus)
NGEF exchanges GTP for GDP on RHOA (Mus musculus)
NGEF exchanges GTP for GDP on RHOA (Homo sapiens)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Homo sapiens)
VAV3 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
VAV3 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
VAV3 is a GEF for Rho/Rac family kinases (Gallus gallus)
VAV3 is a GEF for Rho/Rac family kinases (Xenopus tropicalis)
VAV3 is a GEF for Rho/Rac family kinases (Bos taurus)
VAV3 is a GEF for Rho/Rac family kinases (Canis familiaris)
VAV3 is a GEF for Rho/Rac family kinases (Rattus norvegicus)
VAV3 is a GEF for Rho/Rac family kinases (Mus musculus)
VAV3 is a GEF for Rho/Rac family kinases (Homo sapiens)
Activation of Rho by LARG and PDZ-RhoGEF (Caenorhabditis elegans)
Activation of Rho by LARG and PDZ-RhoGEF (Drosophila melanogaster)
Activation of Rho by LARG and PDZ-RhoGEF (Gallus gallus)
Activation of Rho by LARG and PDZ-RhoGEF (Xenopus tropicalis)
Activation of Rho by LARG and PDZ-RhoGEF (Danio rerio)
Activation of Rho by LARG and PDZ-RhoGEF (Sus scrofa)
Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)
Activation of Rho by LARG and PDZ-RhoGEF (Canis familiaris)
Activation of Rho by LARG and PDZ-RhoGEF (Rattus norvegicus)
Activation of Rho by LARG and PDZ-RhoGEF (Mus musculus)
Activation of Rho by LARG and PDZ-RhoGEF (Homo sapiens)
GEFs activate RhoA,B,C (Saccharomyces cerevisiae)
GEFs activate RhoA,B,C (Schizosaccharomyces pombe)
GEFs activate RhoA,B,C (Caenorhabditis elegans)
GEFs activate RhoA,B,C (Drosophila melanogaster)
GEFs activate RhoA,B,C (Gallus gallus)
GEFs activate RhoA,B,C (Xenopus tropicalis)
GEFs activate RhoA,B,C (Danio rerio)
GEFs activate RhoA,B,C (Sus scrofa)
GEFs activate RhoA,B,C (Bos taurus)
GEFs activate RhoA,B,C (Canis familiaris)
GEFs activate RhoA,B,C (Rattus norvegicus)
GEFs activate RhoA,B,C (Mus musculus)
G13 activation by TP receptor (Caenorhabditis elegans)
G13 activation by TP receptor (Drosophila melanogaster)
G13 activation by TP receptor (Gallus gallus)
G13 activation by TP receptor (Xenopus tropicalis)
G13 activation by TP receptor (Danio rerio)
G13 activation by TP receptor (Sus scrofa)
G13 activation by TP receptor (Bos taurus)
G13 activation by TP receptor (Canis familiaris)
G13 activation by TP receptor (Rattus norvegicus)
G13 activation by TP receptor (Mus musculus)
G13 activation by TP receptor (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
VAV2 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
VAV2 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
VAV2 is a GEF for Rho/Rac family kinases (Gallus gallus)
VAV2 is a GEF for Rho/Rac family kinases (Sus scrofa)
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
VAV2 is a GEF for Rho/Rac family kinases (Canis familiaris)
VAV2 is a GEF for Rho/Rac family kinases (Rattus norvegicus)
VAV2 is a GEF for Rho/Rac family kinases (Mus musculus)
VAV2 is a GEF for Rho/Rac family kinases (Homo sapiens)
An unknown GEF exchanges GTP for GDP on CDC42:GDP (Homo sapiens)
Activation of Rac1 (Caenorhabditis elegans)
Activation of Rac1 (Drosophila melanogaster)
Activation of Rac1 (Xenopus tropicalis)
Activation of Rac1 (Danio rerio)
Activation of Rac1 (Bos taurus)
Activation of Rac1 (Canis familiaris)
Activation of Rac1 (Rattus norvegicus)
Activation of Rac1 (Mus musculus)
Activation of Rac1 (Homo sapiens)
Activation of Cdc42 (Caenorhabditis elegans)
Activation of Cdc42 (Drosophila melanogaster)
Activation of Cdc42 (Xenopus tropicalis)
Activation of Cdc42 (Danio rerio)
Activation of Cdc42 (Bos taurus)
Activation of Cdc42 (Canis familiaris)
Activation of Cdc42 (Rattus norvegicus)
Activation of Cdc42 (Mus musculus)
Activation of Cdc42 (Homo sapiens)
Activation of Cdc42 by pVav1 (Gallus gallus)
Activation of Cdc42 by pVav1 (Xenopus tropicalis)
Activation of Cdc42 by pVav1 (Sus scrofa)
Activation of Cdc42 by pVav1 (Bos taurus)
Activation of Cdc42 by pVav1 (Canis familiaris)
Activation of Cdc42 by pVav1 (Rattus norvegicus)
Activation of Cdc42 by pVav1 (Mus musculus)
Activation of Cdc42 by pVav1 (Homo sapiens)
Activation of Rac1 by pVav1 (Gallus gallus)
Activation of Rac1 by pVav1 (Xenopus tropicalis)
Activation of Rac1 by pVav1 (Sus scrofa)
Activation of Rac1 by pVav1 (Bos taurus)
Activation of Rac1 by pVav1 (Canis familiaris)
Activation of Rac1 by pVav1 (Rattus norvegicus)
Activation of Rac1 by pVav1 (Mus musculus)
Activation of Rac1 by pVav1 (Homo sapiens)
Ras guanyl-nucleotide exchange mediated by Sos1 bound to GRB2 in complex with P-Shc1:P-Erbb2mut (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers (Homo sapiens)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Xenopus tropicalis)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Homo sapiens)
Ras guanyl-nucleotide exchange mediated by Sos1 in complex with GRB2 and P-Erbb2mut (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers. (Homo sapiens)
Intrinsic nucleotide exchange on RAS (Caenorhabditis elegans)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Gallus gallus)
Intrinsic nucleotide exchange on RAS (Xenopus tropicalis)
Intrinsic nucleotide exchange on RAS (Danio rerio)
Intrinsic nucleotide exchange on RAS (Sus scrofa)
Intrinsic nucleotide exchange on RAS (Canis familiaris)
Intrinsic nucleotide exchange on RAS (Rattus norvegicus)
Intrinsic nucleotide exchange on RAS (Mus musculus)
Intrinsic nucleotide exchange on RAS (Homo sapiens)
Intrinsic nucleotide exchange on RAS (Bos taurus)
Activation of RAC1 by the PXN:CRK complex (Dictyostelium discoideum)
Activation of RAC1 by the PXN:CRK complex (Caenorhabditis elegans)
Activation of RAC1 by the PXN:CRK complex (Drosophila melanogaster)
Activation of RAC1 by the PXN:CRK complex (Gallus gallus)
Activation of RAC1 by the PXN:CRK complex (Xenopus tropicalis)
Activation of RAC1 by the PXN:CRK complex (Danio rerio)
Activation of RAC1 by the PXN:CRK complex (Sus scrofa)
Activation of RAC1 by the PXN:CRK complex (Bos taurus)
Activation of RAC1 by the PXN:CRK complex (Canis familiaris)
Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)
Activation of RAC1 by the PXN:CRK complex (Mus musculus)
Activation of RAC1 by the PXN:CRK complex (Homo sapiens)
Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat) (Rattus norvegicus)
GLP1R:GLP1 activates G(s) (Homo sapiens)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Xenopus tropicalis)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Danio rerio)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Sus scrofa)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Bos taurus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Canis familiaris)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Rattus norvegicus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Mus musculus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Homo sapiens)
Glucagon:GCGR mediates GTP-GDP exchange (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
Activation of RAC1 by VAV (Drosophila melanogaster)
Activation of RAC1 by VAV (Gallus gallus)
Activation of RAC1 by VAV (Xenopus tropicalis)
Activation of RAC1 by VAV (Sus scrofa)
Activation of RAC1 by VAV (Bos taurus)
Activation of RAC1 by VAV (Canis familiaris)
Activation of RAC1 by VAV (Rattus norvegicus)
Activation of RAC1 by VAV (Mus musculus)
Activation of RAC1 by VAV (Homo sapiens)
C3G stimulates nucleotide exchange on Rap1 (Rattus norvegicus)
(Frs2)C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Gallus gallus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Mus musculus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Gallus gallus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Xenopus tropicalis)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Sus scrofa)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Rattus norvegicus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Homo sapiens)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Gallus gallus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Xenopus tropicalis)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Danio rerio)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Sus scrofa)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Canis familiaris)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Rattus norvegicus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Mus musculus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Homo sapiens)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Gallus gallus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Xenopus tropicalis)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Danio rerio)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Sus scrofa)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Rattus norvegicus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Gallus gallus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Xenopus tropicalis)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Sus scrofa)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Canis familiaris)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Rattus norvegicus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Mus musculus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Homo sapiens)
Activation of Gq by Muscarinic Acetylcholine Receptor M3 (Mus musculus)
Muscarinic Acetylcholine Receptor M3 activates Gq (Homo sapiens)
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
FFAR1:FFAR1 ligands activate Gq (Canis familiaris)
FFAR1:FFAR1 ligands activate Gq (Rattus norvegicus)
FFAR1:FFAR1 ligands activate Gq (Mus musculus)
FFAR1:FFAR1 ligands activate Gq (Homo sapiens)
Gi activation by P2Y purinoceptor 12 (Caenorhabditis elegans)
Gi activation by P2Y purinoceptor 12 (Drosophila melanogaster)
Gi activation by P2Y purinoceptor 12 (Gallus gallus)
Gi activation by P2Y purinoceptor 12 (Xenopus tropicalis)
Gi activation by P2Y purinoceptor 12 (Danio rerio)
Gi activation by P2Y purinoceptor 12 (Sus scrofa)
Gi activation by P2Y purinoceptor 12 (Bos taurus)
Gi activation by P2Y purinoceptor 12 (Canis familiaris)
Gi activation by P2Y purinoceptor 12 (Rattus norvegicus)
Gi activation by P2Y purinoceptor 12 (Mus musculus)
Gi activation by P2Y purinoceptor 12 (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Caenorhabditis elegans)
Liganded Gs-activating GPCR acts as a GEF for Gs (Drosophila melanogaster)
Liganded Gs-activating GPCR acts as a GEF for Gs (Gallus gallus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Xenopus tropicalis)
Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
Thrombin-activated PARs activate Gq (Caenorhabditis elegans)
Thrombin-activated PARs activate Gq (Gallus gallus)
Thrombin-activated PARs activate Gq (Xenopus tropicalis)
Thrombin-activated PARs activate Gq (Danio rerio)
Thrombin-activated PARs activate Gq (Sus scrofa)
Thrombin-activated PARs activate Gq (Bos taurus)
Thrombin-activated PARs activate Gq (Canis familiaris)
Thrombin-activated PARs activate Gq (Rattus norvegicus)
Thrombin-activated PARs activate Gq (Mus musculus)
Thrombin-activated PARs activate Gq (Homo sapiens)
WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)
WNT:FZD complex promotes G-protein nucleotide exchange (Drosophila melanogaster)
WNT:FZD complex promotes G-protein nucleotide exchange (Gallus gallus)
WNT:FZD complex promotes G-protein nucleotide exchange (Xenopus tropicalis)
WNT:FZD complex promotes G-protein nucleotide exchange (Sus scrofa)
WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)
WNT:FZD complex promotes G-protein nucleotide exchange (Canis familiaris)
WNT:FZD complex promotes G-protein nucleotide exchange (Rattus norvegicus)
WNT:FZD complex promotes G-protein nucleotide exchange (Mus musculus)
WNT:FZD complex promotes G-protein nucleotide exchange (Homo sapiens)
Liganded Gz-activating GPCR acts as a GEF for Gz (Caenorhabditis elegans)
Liganded Gz-activating GPCR acts as a GEF for Gz (Drosophila melanogaster)
Liganded Gz-activating GPCR acts as a GEF for Gz (Gallus gallus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Xenopus tropicalis)
Liganded Gz-activating GPCR acts as a GEF for Gz (Sus scrofa)
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Canis familiaris)
Liganded Gz-activating GPCR acts as a GEF for Gz (Rattus norvegicus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Mus musculus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Dictyostelium discoideum)
Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Gq activation by P2Y purinoceptor 1 (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Thrombin-activated PARs activate G12/13 (Caenorhabditis elegans)
Thrombin-activated PARs activate G12/13 (Gallus gallus)
Thrombin-activated PARs activate G12/13 (Xenopus tropicalis)
Thrombin-activated PARs activate G12/13 (Danio rerio)
Thrombin-activated PARs activate G12/13 (Sus scrofa)
Thrombin-activated PARs activate G12/13 (Bos taurus)
Thrombin-activated PARs activate G12/13 (Canis familiaris)
Thrombin-activated PARs activate G12/13 (Rattus norvegicus)
Thrombin-activated PARs activate G12/13 (Mus musculus)
Thrombin-activated PARs activate G12/13 (Homo sapiens)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Caenorhabditis elegans)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Drosophila melanogaster)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Gallus gallus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Xenopus tropicalis)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Danio rerio)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Sus scrofa)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Canis familiaris)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Rattus norvegicus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Mus musculus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Homo sapiens)
PCK1 phosphorylates OA to yield PEP (Dictyostelium discoideum)
PCK1 phosphorylates OA to yield PEP (Caenorhabditis elegans)
PCK1 phosphorylates OA to yield PEP (Drosophila melanogaster)
PCK1 phosphorylates OA to yield PEP (Gallus gallus)
PCK1 phosphorylates OA to yield PEP (Xenopus tropicalis)
PCK1 phosphorylates OA to yield PEP (Danio rerio)
PCK1 phosphorylates OA to yield PEP (Sus scrofa)
PCK1 phosphorylates OA to yield PEP (Bos taurus)
PCK1 phosphorylates OA to yield PEP (Canis familiaris)
PCK1 phosphorylates OA to yield PEP (Rattus norvegicus)
PCK1 phosphorylates OA to yield PEP (Mus musculus)
PCK1 phosphorylates OA to yield PEP (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
GTP loading by Rheb (Saccharomyces cerevisiae)
GTP loading by Rheb (Schizosaccharomyces pombe)
GTP loading by Rheb (Dictyostelium discoideum)
GTP loading by Rheb (Caenorhabditis elegans)
GTP loading by Rheb (Drosophila melanogaster)
GTP loading by Rheb (Gallus gallus)
GTP loading by Rheb (Xenopus tropicalis)
GTP loading by Rheb (Danio rerio)
GTP loading by Rheb (Sus scrofa)
GTP loading by Rheb (Bos taurus)
GTP loading by Rheb (Canis familiaris)
GTP loading by Rheb (Rattus norvegicus)
GTP loading by Rheb (Mus musculus)
GTP loading by Rheb (Homo sapiens)
as a member of
(d)NDP [cytosol]
(d)GDP [cytosol]
Purine nucleotide [cytosol]
This entity regulates
Negatively
inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate
(Mus musculus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Saccharomyces cerevisiae)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Caenorhabditis elegans)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Xenopus tropicalis)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Danio rerio)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Canis familiaris)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Mus musculus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Plasmodium falciparum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Schizosaccharomyces pombe)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Dictyostelium discoideum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Drosophila melanogaster)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Gallus gallus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Sus scrofa)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Homo sapiens)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
(Rattus norvegicus)
Other forms of this molecule
GDP [endocytic vesicle lumen]
GDP [Golgi lumen]
GDP [extracellular region]
GDP [mitochondrial matrix]
Cross References
COMPOUND
C00035
ZINC
000008215481
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text