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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
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How do I search ?
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GTP [cytosol]
Stable Identifier
R-ALL-29438
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Guanosine 5'-triphosphate, GTP)(4-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Active MTORC1 binds the ULK1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Active MTORC1 phosphorylates ULK1 (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1 dissociates from ULK complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Selective autophagy (Bos taurus)
Aggrephagy (Bos taurus)
Aggresome dissociates from dynein and microtubule (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
RAN stimulates fusion of nuclear envelope (NE) membranes (Bos taurus)
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAN:GTP recruits nuclear envelope (NE) membranes (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
GTP [cytosol]
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 binds to microtubules (Bos taurus)
EML4 homotrimer:Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinetochore capture of astral microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic Prophase (Bos taurus)
Golgi Cisternae Pericentriolar Stack Reorganization (Bos taurus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Bos taurus)
GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Bos taurus)
RAB2A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Bos taurus)
RAB2A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
PLK1 phosphorylates GORASP1 (Bos taurus)
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP [Golgi membrane] (Bos taurus)
p-RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
PLK1 phosphorylates OPTN (Bos taurus)
OPTN:RAB8A:GTP [Golgi membrane] (Bos taurus)
RAB8A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to mechanical stimuli (Bos taurus)
Response of endothelial cells to shear stress (Bos taurus)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Bos taurus)
ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G alpha (s):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGA,B hydrolyzes GTP (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGC,D exchanges GTP for GDP (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGC,D hydrolyzes GTP (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 binds RHEB:GTP (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Developmental Biology (Bos taurus)
Myogenesis (Bos taurus)
Nuclear translocation of p38 MAPK (Bos taurus)
ABL1:JLP:CDO complex [plasma membrane] (Bos taurus)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Bos taurus)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Bos taurus)
ABL1:JLP:CDO complex [plasma membrane] (Bos taurus)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Bos taurus)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH-ephrin mediated repulsion of cells (Bos taurus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHA-mediated growth cone collapse (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
CDC42 and PIP2 bind WASL, activating it (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
N-WASP binds ARP2/3 and G-actin (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1 autophosphorylates (Bos taurus)
RAC1-GTP:p-S144,T423-PAK1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1 binds RAC1:GTP (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP binds ROCK, activating it (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ras:GTP binds p120-RasGAP (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Bos taurus)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ephrin signaling (Bos taurus)
PAK binds RAC and bPIX (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAKs autophosphorylate (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAKs phosphorylate MLC (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
bPIX exchanges GTP for GDP on RAC, activating it (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Formation of clathrin coated vesicle (Bos taurus)
GTP [cytosol]
Signal transduction by L1 (Bos taurus)
Activation of Rac1 by VAV2 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Interaction of PAK1 with Rac1-GTP (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
pPAK1:Rac1-GTP [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Activation of Cdc42 (Bos taurus)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rac1 (Bos taurus)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment and activation of N-WASP by Cdc42 (Bos taurus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Bos taurus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Semaphorin interactions (Bos taurus)
Sema3A PAK dependent Axon repulsion (Bos taurus)
Activation of PAK by Rac1 (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of LIMK-1 by PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROCK activation by RHO (Bos taurus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Bos taurus)
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Bos taurus)
Active Rac1 interacts with Plexin-B1:Sema4D (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Bos taurus)
R-Ras-GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Inactivation of Rho-GTP by p190RhoGAP (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Bos taurus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rnd1 interacts with Plexin-B1:Sema4D (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p190RhoGAP binds Plexin-B1 (Bos taurus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Bos taurus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by ROBO receptors (Bos taurus)
SLIT2:ROBO1 increases RHOA activity (Bos taurus)
MYO9B inactivates RHOA (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gene expression (Transcription) (Bos taurus)
Gene Silencing by RNA (Bos taurus)
Transcriptional regulation by small RNAs (Bos taurus)
Importin-8 imports AGO2:miRNA into the nucleus (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Tie2 Signaling (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Factors involved in megakaryocyte development and platelet production (Bos taurus)
Kinesins (Bos taurus)
Kinesins bind microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)
GTP [cytosol]
VAV1 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
GTP [cytosol]
VAV2 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Bos taurus)
GTP [cytosol]
VAV3 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activated integrin alphaIIb beta3 binds SHC1 (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Talin (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PTK2 at Y397 (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Clustering of Integrin alphaIIb beta3 complexes (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dephosphorylation of inactive SRC by PTPB1 (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3 activation (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Interaction of integrin alphaIIb beta3 with Fibrinogen (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Release of CSK from SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 dissociates from integrin alphaIIb beta3 (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SYK activation by SRC (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SYK binds to integrin alphaIIb beta3 (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Translocation of PTK2 to Focal complexes (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Translocation of RIAM to plasma membrane (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 1 (Bos taurus)
Dissociation of the P2Y purinoceptor 1:Gq complex (Bos taurus)
ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Dissociation of the P2Y purinoceptor 12:Gi complex (Bos taurus)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gi activation by P2Y purinoceptor 12 (Bos taurus)
GTP [cytosol]
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thromboxane signalling through TP receptor (Bos taurus)
Dissociation of the TP:G13 complex (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dissociation of the TP:Gq complex (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G13 activation by TP receptor (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gq activation by TP receptor (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
Thrombin-activated PARs activate G12/13 (Bos taurus)
GTP [cytosol]
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Bos taurus)
G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs activate Gq (Bos taurus)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs:G12/13 (active) dissociate (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Bos taurus)
G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs:Gq (active) dissociate (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Platelet homeostasis (Bos taurus)
Prostacyclin signalling through prostacyclin receptor (Bos taurus)
Gs activation by prostacyclin receptor (Bos taurus)
GTP [cytosol]
Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
G alpha (s):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Budding of COPII coated vesicle (Bos taurus)
COPII vesicle with MHC class I [lumenal side of endoplasmic reticulum membrane] (Bos taurus)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Coat Assembly (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Disassembly of COPII coated vesicle (Bos taurus)
GTP [cytosol]
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Bos taurus)
COPII vesicle with MHC class I [lumenal side of endoplasmic reticulum membrane] (Bos taurus)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
MHC class II antigen presentation (Bos taurus)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Bos taurus)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Bos taurus)
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Formation of COPII vesicle (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Fusion of COPII vesicle with Golgi complex (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Internalization of MHC II:Ii clathrin coated vesicle (Bos taurus)
GTP [cytosol]
TGN-lysosomal vesicle coat assembly (Bos taurus)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Bos taurus)
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Bos taurus)
GTP [cytosol]
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rap1 signalling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rap1 signal termination by Rap1GAPs (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Regulation of T cell activation by CD28 family (Bos taurus)
Co-stimulation by CD28 (Bos taurus)
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Cdc42 by pVav1 (Bos taurus)
GTP [cytosol]
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of PAKs by RAC1 and CDC42 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rac1 by pVav1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
Activation of RAC1 by VAV2/3 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
GTP [cytosol]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of PAK to the membrane by binding active RAC1 (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Bos taurus)
Mother filament:branching complex [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ABL phosphorylates WAVEs (Bos taurus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of RAC1 by VAV (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK1 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Detachment of WASP/WAVE (Bos taurus)
Mother filament:branching complex [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 and CDC42 activate PAK1 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Src phosphorylate WASP,N-WASP (Bos taurus)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Bos taurus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROS and RNS production in phagocytes (Bos taurus)
NOX2 generates superoxide anion from oxygen (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Mitochondrial Uncoupling (Bos taurus)
UCP1 imports a proton (Bos taurus)
Purine nucleotide [cytosol]
GTP [cytosol]
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Acetylcholine regulates insulin secretion (Bos taurus)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Bos taurus)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Bos taurus)
G-alpha(q) 11,14,15,Q:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
GTP [cytosol]
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gi,Go Heterotrimeric G-protein complex dissociates (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Bos taurus)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Bos taurus)
G-alpha(q) 11,14,15,Q:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
GTP [cytosol]
G-alpha(q)11,14,15,Q:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(q) 11,14,15,Q:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)
RAP1A exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
RAP1A:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PCK1 phosphorylates OA to yield PEP (Bos taurus)
GTP [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)
(d)NTP [cytosol]
GTP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Bos taurus)
(d)NTP [cytosol]
GTP [cytosol]
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
GTP [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Bos taurus)
GCH1 reduces GTP to dihydroneopterin triphosphate (Bos taurus)
GTP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Molybdenum cofactor biosynthesis (Bos taurus)
Cyclisation of GTP to precursor Z (Bos taurus)
GTP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
GDP-fucose biosynthesis (Bos taurus)
FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Bos taurus)
GTP [cytosol]
Synthesis of GDP-mannose (Bos taurus)
GMPPB converts Mannose-1-phosphate to GDP-Mannose (Bos taurus)
GTP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ARFGAPs stimulate ARF GTPase activity (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Active ARF recruits coatomer (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SEC31:SEC13 and v-SNARE recruitment (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 binds RAB1:GTP (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Vesicle budding (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Cargo concentration in the ER (Bos taurus)
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglycylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Bos taurus)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglycyl alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
TTLLs polyglutamylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglutamylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglutamyl microtubule protofilament [cytosol] (Bos taurus)
Polyglutamyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglutamyl alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Elongation (Bos taurus)
Peptide chain elongation (Bos taurus)
GTP-binding activates eEF2 (Bos taurus)
GTP [cytosol]
eEF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Regeneration of eEF1A:GTP by eEF1B activity (Bos taurus)
GTP [cytosol]
eEF1A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Bos taurus)
Translation initiation complex formation (Bos taurus)
Formation of translation initiation complexes containing mRNA that does not circularize (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of the ternary complex, and subsequently, the 43S complex (Bos taurus)
De novo formation of eIF2:GTP (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of the 43S pre-initiation complex (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GTP hydrolysis and joining of the 60S ribosomal subunit (Bos taurus)
The 60S subunit joins the translation initiation complex (Bos taurus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Bos taurus)
eIF5B:GTP [cytosol] (Bos taurus)
GTP [cytosol]
eIF5B:GTP [cytosol] (Bos taurus)
GTP [cytosol]
eIF5B:GTP is hydrolyzed and released (Bos taurus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Bos taurus)
eIF5B:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Recycling of eIF2:GDP (Bos taurus)
eIF2 activation (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ribosomal scanning and start codon recognition (Bos taurus)
Ribosomal scanning (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Start codon recognition (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
L13a-mediated translational silencing of Ceruloplasmin expression (Bos taurus)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Eukaryotic Translation Termination (Bos taurus)
N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Bos taurus)
ETF1 dimer:eRF3:GTP [cytosol] (Bos taurus)
eRF3:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Me-Q185-ETF1 dimer:eRF3:GTP [cytosol] (Bos taurus)
eRF3:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
GABA receptor activation (Bos taurus)
GABA B receptor activation (Bos taurus)
Activation of GABAB receptors (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
ATAT acetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
Ac K40 alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Anchoring of the basal body to the plasma membrane (Bos taurus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cargo trafficking to the periciliary membrane (Bos taurus)
BBSome-mediated cargo-targeting to cilium (Bos taurus)
ARL6:GTP and the BBSome bind ciliary cargo (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARL6:GTP and the BBSome target cargo to the primary cilium (Bos taurus)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VxPx cargo-targeting to cilium (Bos taurus)
ARF4:GTP binds VxPx-motifs of membrane proteins (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Bos taurus)
ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ASAP1 stimulates GTPase activity of ARF4 (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cargo-carrying vesicles bud from the TGN (Bos taurus)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
GTP [cytosol]
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3IP and RAB8A bind to the ciliary targeting complex (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GTP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
The exocyst complex binds to RAB3IP in the ciliary targeting complex (Bos taurus)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Bos taurus)
exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
HDAC6 deacetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
Ac K40 alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Activation of the phototransduction cascade (Bos taurus)
Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 (Bos taurus)
GNAT1-GTP [photoreceptor disc membrane] (Bos taurus)
GTP [cytosol]
Gt-GTP [photoreceptor disc membrane] (Bos taurus)
GNAT1-GTP [photoreceptor disc membrane] (Bos taurus)
GTP [cytosol]
PDE6 hydrolyses cGMP to GMP (Bos taurus)
GNAT1-GTP:PDE6 [photoreceptor disc membrane] (Bos taurus)
GNAT1-GTP [photoreceptor disc membrane] (Bos taurus)
GTP [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
GNAT1-GTP hydrolyses its bound GTP to GDP (Bos taurus)
GNAT1-GTP:PDE6 [photoreceptor disc membrane] (Bos taurus)
GNAT1-GTP [photoreceptor disc membrane] (Bos taurus)
GTP [cytosol]
GUCYs converts GTP to cGMP (Bos taurus)
GTP [cytosol]
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
p75 NTR receptor-mediated signalling (Bos taurus)
Cell death signalling via NRAGE, NRIF and NADE (Bos taurus)
NRAGE signals death through JNK (Bos taurus)
GTP-bound RAC contributes to JNK activation (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)
GTP [cytosol]
GEFs [cytosol] (Bos taurus)
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p75NTR regulates axonogenesis (Bos taurus)
Axonal growth inhibition (RHOA activation) (Bos taurus)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin signaling (Bos taurus)
Activated integrin alphaIIb beta3 binds SHC1 (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Talin (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PTK2 at Y397 (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Clustering of Integrin alphaIIb beta3 complexes (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dephosphorylation of inactive SRC by PTPB1 (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3 activation (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Interaction of integrin alphaIIb beta3 with Fibrinogen (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Release of CSK from SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 dissociates from integrin alphaIIb beta3 (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SYK activation by SRC (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SYK binds to integrin alphaIIb beta3 (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Translocation of PTK2 to Focal complexes (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Translocation of RIAM to plasma membrane (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
MAF1 translocates to the nucleus (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 phosphorylates MAF1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAC1,RAC2,RHOG activate PI3K (Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Intrinsic nucleotide exchange on RAS (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAP2K and MAPK activation (Bos taurus)
Dissociation of RAS:RAF complex (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
BRAP autoubiquitinates (Bos taurus)
p21 RAS:GTP:BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:ub-BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
BRAP binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PEBP1 binds activated RAF1 (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PP2A dephosphorylates RAF1 (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PP5 dephosphorylates RAF1 S338 (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAF activation (Bos taurus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Bos taurus)
S-GCC MRAS:GTP:SHOC2:PP1 [plasma membrane] (Bos taurus)
S-GCC MRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of RAF (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Raf dimer inhibitors bind RAF heterodimers (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS processing (Bos taurus)
ARL2:GTP bind PDE6D on KRAS4B (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
KRAS4B recycles to the plasma membrane (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAS:GTP binds PI3K (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:PI3K [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS:GTP binds RAL GDS proteins (Bos taurus)
S-Farn-Me-2xPalmS HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
S-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteins [plasma membrane] (Bos taurus)
S-Farn-Me-2xPalmS HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAPK6/MAPK4 signaling (Bos taurus)
Activation of PAKs by RAC1 and CDC42 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK1,2,3 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Bos taurus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MTOR signalling (Bos taurus)
AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of active mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GTP loading by Rheb (Bos taurus)
GTP [cytosol]
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rag dimer formation (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator binds Rag dimers (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SLC38A9 binds Ragulator:Rag dimers (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1-mediated signalling (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
BTK in G alpha (12)-BTK complex is activated (Bos taurus)
G alpha (12):BTK [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (12) binds BTK (Bos taurus)
G alpha (12):BTK [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Bos taurus)
G alpha (12):BTK [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GEFs activate RhoA,B,C (Bos taurus)
GTP [cytosol]
GEFs [cytosol] (Bos taurus)
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
LARG activation by G alpha 12/13 (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (12/13):LARG [plasma membrane] (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
LARG binds plexin B1 (Bos taurus)
G-protein alpha (12/13):LARG [plasma membrane] (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane] (Bos taurus)
G-protein alpha (12/13):LARG [plasma membrane] (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Bos taurus)
G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROCK activation by RHO (Bos taurus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Bos taurus)
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
The Ligand:GPCR:G12/13 complex dissociates (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Bos taurus)
G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p115-RhoGEF activation of RHOA (Bos taurus)
GTP [cytosol]
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i) signalling events (Bos taurus)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i):GTP:RGS [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)
G alpha (i):GTP:RGS [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i):GTP:SRC-1 [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Bos taurus)
G-alpha(t)-GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Bos taurus)
G-alpha(t)-GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Opioid Signalling (Bos taurus)
G-protein activation (Bos taurus)
G-protein alpha subunit is inactivated (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
The receptor:G-protein complex binds GTP (Bos taurus)
GTP [cytosol]
Opioid:MOR:G protein-GTP complex [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
The receptor:G-protein complex dissociates (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Opioid:MOR:G protein-GTP complex [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein mediated events (Bos taurus)
Adenylate cyclase activating pathway (Bos taurus)
Adenylate cyclase converts ATP into cyclic AMP (Bos taurus)
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Galpha-olf:GTP binds to adenylate cyclase and activates it (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC beta mediated events (Bos taurus)
Inactivation of PLC beta (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PIP2 hydrolysis (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Opsins act as GEFs for G alpha-t (Bos taurus)
GTP [cytosol]
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Bos taurus)
G-alpha(t)-GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) signalling events (Bos taurus)
Active G alpha (q) binds RGS proteins (Bos taurus)
G alpha (q):GTP:RGS [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Active Gq binds BTK (Bos taurus)
Active Gq:BTK [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
BTK in active Gq-BTK complex is activated (Bos taurus)
Active Gq:BTK [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) binds to Trio family RhoGEFs (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) in G (q):RGS complex is inactivated (Bos taurus)
G alpha (q):GTP:RGS [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) inhibits PI3K alpha (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (q/11):PI3K alpha [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
GRK2 sequesters activated Gq (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (q):GRK2 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
EGFR Transactivation by Gastrin (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gq-BTK complex dissociates to Active BTK and Gq (Bos taurus)
Active Gq:BTK [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC-beta hydrolyses PIP2 to DAG and IP3 (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC-beta:G-alpha(q/11):DAG:IP3 [plasma membrane] (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC-beta:G-alpha(q/11):PIP2 [plasma membrane] (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (s) signalling events (Bos taurus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
GTP [cytosol]
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
G alpha (s):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (z) signalling events (Bos taurus)
Active G alpha (z) binds RGS proteins (Bos taurus)
G alpha (z):GTP:RGS16,17,20 [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (z) in G alpha (z):RGS complex is inactivated (Bos taurus)
G alpha (z):GTP:RGS16,17,20 [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (z) inhibits adenylate cyclase (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
GTP [cytosol]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
The Ligand:GPCR:Gz complex dissociates (Bos taurus)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein beta:gamma signalling (Bos taurus)
G beta:gamma signalling through CDC42 (Bos taurus)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Bos taurus)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Bos taurus)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Hedgehog (Bos taurus)
Hedgehog 'off' state (Bos taurus)
KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
alpha tubulin:GTP [axonemal microtubule] (Bos taurus)
GTP [cytosol]
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
alpha tubulin:GTP [axonemal microtubule] (Bos taurus)
GTP [cytosol]
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
alpha tubulin:GTP [axonemal microtubule] (Bos taurus)
GTP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
ARHGAP35 binds RHOA:GTP (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARHGAP35 stimulates RHOA GTPase activity (Bos taurus)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RASA1 binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:RASA1 [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RASA1 stimulates RAS GTPase activity (Bos taurus)
p21 RAS:GTP:RASA1 [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
EGFR downregulation (Bos taurus)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ub-Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP binds CBL:Beta-Pix (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CBL:Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by ERBB2 (Bos taurus)
ERBB2 Regulates Cell Motility (Bos taurus)
MEMO1 binds RHOA:GTP:DIAPH1 (Bos taurus)
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2 events in ERBB2 signaling (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by ERBB4 (Bos taurus)
SHC1 events in ERBB4 signaling (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by MET (Bos taurus)
MET activates RAS signaling (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MET promotes cell motility (Bos taurus)
MET activates RAP1 and RAC1 (Bos taurus)
DOCK7 activates RAC1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAPGEF1 activates RAP1 (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MET receptor recycling (Bos taurus)
GGA3 associates with activated MET receptor (Bos taurus)
ARF6:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Bos taurus)
ARF6:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Bos taurus)
GGC-RAB4:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Bos taurus)
ARF6:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
ARMS-mediated activation (Bos taurus)
C3G stimulates nucleotide exchange on Rap1 (Bos taurus)
GTP [cytosol]
Rap1-GTP [cytosol] (Bos taurus)
GTP [cytosol]
Frs2-mediated activation (Bos taurus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Bos taurus)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)
RAP1:GTP:B-Raf complex [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
Dissociation of phosphorylated MAP2Ks and MAPKs (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Bos taurus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
Signalling to RAS (Bos taurus)
p38MAPK events (Bos taurus)
Ral-GDS binds to Ras-GTP (Bos taurus)
Ras-GTP:RalGDS complex [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by NTRK2 (TRKB) (Bos taurus)
Activated NTRK2 signals through FYN (Bos taurus)
NTRK2 activates RAC1 (Bos taurus)
DOCK3 activates RAC1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by PDGF (Bos taurus)
Downstream signal transduction (Bos taurus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by SCF-KIT (Bos taurus)
Activation of RAC1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Bos taurus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
CDC42:GTP binds PAK2 (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Bos taurus)
PAK2 dimer:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FYN phosphorylates PAK2 (Bos taurus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Bos taurus)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Bos taurus)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NADPH oxidase 2 (NOX2) complex binds RAC1 (Bos taurus)
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK2 autophorylates (Bos taurus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Bos taurus)
PAK2 dimer:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Bos taurus)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROCK1,ROCK2 are activated (Bos taurus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VEGFR2 mediated cell proliferation (Bos taurus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VEGFR2 mediated vascular permeability (Bos taurus)
PAK1-3 autophosphorylates (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1-3 dimer disassociates (Bos taurus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 binds PAK1-3 (Bos taurus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p38 MAPK activation by VEGFR (Bos taurus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Bos taurus)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Miro GTPase Cycle (Bos taurus)
RHOT1 GTPase cycle (Bos taurus)
RHOT1 binds effectors at the mitochondrial outer membrane (Bos taurus)
RHOT1:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOT1:GTP:RHOT1 effectors [mitochondrial outer membrane] (Bos taurus)
RHOT1:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOT1 hydrolyzes GTP (Bos taurus)
RHOT1:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOT2 GTPase cycle (Bos taurus)
RHOT2 binds effectors at the mitochondrial outer membrane (Bos taurus)
RHOT2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOT2:GTP:RHOT2 effectors [mitochondrial outer membrane] (Bos taurus)
RHOT2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOT2 hydrolyzes GTP (Bos taurus)
RHOT2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
CDC42:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
CDC42:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Activated FMNL3 binds G-actin (Bos taurus)
RHOC:GTP:FMNL3 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:FMNL3:G-actin [plasma membrane] (Bos taurus)
RHOC:GTP:FMNL3 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP recruits DIAPH2-2 to kinetochores (Bos taurus)
CDC42:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
CDC42:GTP [cytosol] (Bos taurus)
GTP [cytosol]
CDC42:GTP:FMNL2 binds Profilin:G-actin (Bos taurus)
CDC42:FMNL2:Profilin:G-actin [plasma membrane] (Bos taurus)
CDC42:GTP:FMNL2 [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:FMNL2 [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
DAAM1 recruits GTP-bound RHOA (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
ppDVL:DAAM1:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
DIAPH1 binds RHOA:GTP (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FMNL2 binds CDC42:GTP (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:FMNL2 [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FMNL2 binds RHOC:GTP (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:FMNL2 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FMNL3 binds RHOC:GTP (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:FMNL3 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
CDC42:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RHOD:GTP recruits DAIPH2-3 to endosomes (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:DIAPH2-3 [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Bos taurus)
RHOD:GTP:DIAPH2-3 [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:DIAPH2:SRC-1 [endosome membrane] (Bos taurus)
RHOD:GTP:DIAPH2-3 [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Bos taurus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate NADPH Oxidases (Bos taurus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Bos taurus)
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
NOX1 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
NOX3 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP binds NOX1 complex (Bos taurus)
NOX1 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP binds NOX3 complex (Bos taurus)
NOX3 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP binds NOX2 complex (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate ROCKs (Bos taurus)
ROCK activation by RHO (Bos taurus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Bos taurus)
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate Rhotekin and Rhophilins (Bos taurus)
RHOA:GTP binds RHPN1 or RHPN2 (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RTKN binds LIN7B (Bos taurus)
RHOA:GTP:RTKN [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RTKN:LIN7B [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RTKN binds TAX1BP3 (Bos taurus)
RHOA:GTP:RTKN [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RTKN:TAX1BP3 [plasma membrane] (Bos taurus)
RHOA:GTP:RTKN [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Bos taurus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Bos taurus)
Mother filament:branching complex [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ABL phosphorylates WAVEs (Bos taurus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Detachment of WASP/WAVE (Bos taurus)
Mother filament:branching complex [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Src phosphorylate WASP,N-WASP (Bos taurus)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Bos taurus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate CIT (Bos taurus)
Activated CIT binds KIF14 and PRC1 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:CIT:KIF14:PRC1 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CIT-3 binds DLG4 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3:DLG4 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate IQGAPs (Bos taurus)
GTP-bound RAC1 and CDC42 bind IQGAPs (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Bos taurus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
IQGAP1 binds CLIP1 and microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
IQGAPs bind CALM1 (Bos taurus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Bos taurus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
IQGAPs bind F-actin, which is inhibited by calmodulin (Bos taurus)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Bos taurus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Bos taurus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate KTN1 (Bos taurus)
Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOG,RAC1,CDC42:GTP:KTN1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
KTN1 binds Kinesin-1 (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP:KTN1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOG,RAC1,CDC42:GTP:KTN1:Kinesin-1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP:KTN1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate PAKs (Bos taurus)
Autophosphorylation of PAK1,2,3 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Bos taurus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 and CDC42 activate PAK1 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 and CDC42 activate PAK2 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 and CDC42 activate PAK3 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate PKNs (Bos taurus)
PDPK1 phosphorylates PKN1,2,3 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases regulate CFTR trafficking (Bos taurus)
RHOQ binds GOPC:CFTR (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Bos taurus)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP:GOPC:CFTR [plasma membrane] (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPase cycle (Bos taurus)
CDC42 GTPase cycle (Bos taurus)
CDC42 GAPs stimulate CDC42 GTPase activity (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42 GEFs activate CDC42 (Bos taurus)
GTP [cytosol]
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42 binds effectors at the ER membrane (Bos taurus)
CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:CDC42 endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
CDC42 translocates to the endoplasmic reticulum membrane (Bos taurus)
CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 GTPase cycle (Bos taurus)
RAC1 GAPs stimulate RAC1 GTPase activity (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 GEFs activate RAC1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 binds effectors at the ER membrane (Bos taurus)
RAC1:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP:RAC1 endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RAC1:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC1 binds effectors at the plasma membrane (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 translocates to the endoplasmic reticulum membrane (Bos taurus)
RAC1:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 GTPase cycle (Bos taurus)
RAC2 GAPs stimulate RAC2 GTPase activity (Bos taurus)
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 GEFs activate RAC2 (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the ER membrane (Bos taurus)
RAC2:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP:RAC2 endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RAC2:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the mitochondrial outer membrane (Bos taurus)
RAC2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP:RAC2 mitochondrial effectors [mitochondrial outer membrane] (Bos taurus)
RAC2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the phagocytic vesicle membrane (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the plasma membrane (Bos taurus)
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Bos taurus)
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 translocates to the ER membrane (Bos taurus)
RAC2:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 translocates to the mitochondrial membrane (Bos taurus)
RAC2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 translocates to the phagocytic vesicle membrane (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 GTPase cycle (Bos taurus)
RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 GEFs activate RAC3 (Bos taurus)
GTP [cytosol]
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 binds ER effectors (Bos taurus)
RAC3:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC3:GTP:RAC3 endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RAC3:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC3 binds effectors at the plasma membrane (Bos taurus)
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Bos taurus)
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 translocates to the endoplasmic reticulum membrane (Bos taurus)
RAC3:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA GTPase cycle (Bos taurus)
RHOA GAPs stimulate RHOA GTPase activity (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA GEFs activate RHOA (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA binds effectors at the ER membrane (Bos taurus)
RHOA:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RHOA:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA binds effectors at the plasma membrane (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP translocates to the ER membrane (Bos taurus)
RHOA:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOBTB GTPase Cycle (Bos taurus)
RHOBTB1 GTPase cycle (Bos taurus)
RHOBTB1 binds GTP (Bos taurus)
GTP [cytosol]
RHOBTB1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOBTB1 binds interacting proteins at the endosome membrane (Bos taurus)
RHOBTB1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Bos taurus)
RHOBTB1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOBTB2 GTPase cycle (Bos taurus)
RHOBTB2 binds GTP (Bos taurus)
GTP [cytosol]
RHOBTB2:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOBTB2 binds interacting proteins at the endosome membrane (Bos taurus)
RHOBTB2:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOBTB2:GTP:RHOBTB2 interacting proteins [endosome membrane] (Bos taurus)
RHOBTB2:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOC GTPase cycle (Bos taurus)
RHOC GAPs stimulate RHOC GTPase activity (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC GEFs activate RHOC (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC activates endoplasmic reticulum effectors (Bos taurus)
RHOC:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:RHOC endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RHOC:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOC binds effectors at the plasma membrane (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:RHOC effectors [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC translocates to the endoplasmic reticulum membrane (Bos taurus)
RHOC:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD GTPase cycle (Bos taurus)
RHOD GAPs stimulate RHOD GTPase activity (Bos taurus)
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD auto-activates (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the Golgi membrane (Bos taurus)
RHOD:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD Golgi membrane effectors [Golgi membrane] (Bos taurus)
RHOD:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the endosome membrane (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD endosome effectors [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the mitochondrial outer membrane (Bos taurus)
RHOD:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD mitochondrial outer membrane effectors [mitochondrial outer membrane] (Bos taurus)
RHOD:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the plasma membrane (Bos taurus)
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Bos taurus)
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD translocates to the Golgi membrane (Bos taurus)
RHOD:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD translocates to the mitochondrial outer membrane (Bos taurus)
RHOD:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP translocates to the endosome membrane (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF GTPase cycle (Bos taurus)
RHOF GAPs stimulate RHOF GTPase activity (Bos taurus)
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF auto-activates (Bos taurus)
GTP [cytosol]
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF binds effectors at the plasma membrane (Bos taurus)
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF:GTP:RHOF effectors [plasma membrane] (Bos taurus)
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG GTPase cycle (Bos taurus)
RHOG GAPs stimulate RHOG GTPase activity (Bos taurus)
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG GEFs activate RHOG (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG binds effectors at the ER membrane (Bos taurus)
RHOG:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP:RHOG endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RHOG:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOG binds effectors at the plasma membrane (Bos taurus)
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Bos taurus)
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG translocates to the ER membrane (Bos taurus)
RHOG:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOH GTPase cycle (Bos taurus)
GDIs bind RHOH (Bos taurus)
RHOH:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOH:GTP:RHOH GDIs [cytosol] (Bos taurus)
RHOH:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOH binds GTP (Bos taurus)
GTP [cytosol]
RHOH:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOH binds effectors at the plasma membrane (Bos taurus)
RHOH:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOH:GTP:RHOH effectors [plasma membrane] (Bos taurus)
RHOH:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOJ GTPase cycle (Bos taurus)
RHOJ GAPs stimulate RHOJ GTPase activity (Bos taurus)
RHOJ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOJ GEFs activate RHOJ (Bos taurus)
GTP [cytosol]
RHOJ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ GTPase cycle (Bos taurus)
RHOQ GAPs stimulate RHOQ GTPase activity (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ GEFs activate RHOQ (Bos taurus)
GTP [cytosol]
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ binds GOPC:CFTR (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ binds effectors at the plasma membrane (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP:RHOQ effectors [plasma membrane] (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ translocates to the Golgi-associated vesicle membranes (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOU GTPase cycle (Bos taurus)
RHOU auto-activates (Bos taurus)
GTP [cytosol]
RHOU:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOU binds effectors at the plasma membrane (Bos taurus)
RHOU:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOU:GTP:RHOU effectors [plasma membrane] (Bos taurus)
RHOU:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOV GTPase cycle (Bos taurus)
RHOV binds GTP (Bos taurus)
GTP [cytosol]
RHOV:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOV binds effectors at the plasma membrane (Bos taurus)
RHOV:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOV:GTP:RHOV effectors [plasma membrane] (Bos taurus)
RHOV:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND1 GTPase cycle (Bos taurus)
RND1 binds GTP (Bos taurus)
GTP [cytosol]
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND1 binds effectors (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND1:GTP:RND1 effectors [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND2 GTPase cycle (Bos taurus)
RND2 binds GTP (Bos taurus)
GTP [cytosol]
RND2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND2 binds effectors (Bos taurus)
RND2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND2:GTP:RND2 effectors [plasma membrane] (Bos taurus)
RND2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND3 GTPase cycle (Bos taurus)
RND3 binds GTP (Bos taurus)
GTP [cytosol]
RND3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND3 binds effectors (Bos taurus)
RND3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND3:GTP:RND3 effectors [plasma membrane] (Bos taurus)
RND3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by WNT (Bos taurus)
Beta-catenin independent WNT signaling (Bos taurus)
Ca2+ pathway (Bos taurus)
G-protein subunits dissociate from WNT:FZD complex (Bos taurus)
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Bos taurus)
G-protein alpha (o/t2):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PDE6 hydrolyses cGMP to GMP (Bos taurus)
GNAT2:PDE6 [plasma membrane] (Bos taurus)
GNAT2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)
GTP [cytosol]
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Bos taurus)
G-protein alpha (o/t2):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PCP/CE pathway (Bos taurus)
DAAM1 recruits GTP-bound RHOA (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
ppDVL:DAAM1:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
ppDVL recruits RAC (Bos taurus)
RAC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
pp-DVL:RAC:GTP [plasma membrane] (Bos taurus)
RAC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Transport of small molecules (Bos taurus)
Aquaporin-mediated transport (Bos taurus)
Vasopressin regulates renal water homeostasis via Aquaporins (Bos taurus)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
AVPR2:AVP:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G alpha (s):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
ARL2:GTP binds ARL2BP (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARL2:GTP:ARL2BP [cytosol] (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Bos taurus)
ARL2:GTP:ARL2BP [cytosol] (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Clathrin-mediated endocytosis (Bos taurus)
BAR domain proteins recruit dynamin (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GGC-RAB5:GTP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Endophilins recruit synaptojanins to the clathrin-coated pit (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Recruitment of AP-2 complex and clathrin (Bos taurus)
ARFGAP1:ARF6:GTP [cytosol] (Bos taurus)
ARF6:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
DNM:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ARFGAPs stimulate ARF GTPase activity (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Active ARF recruits coatomer (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SEC31:SEC13 and v-SNARE recruitment (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 binds RAB1:GTP (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Vesicle budding (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Cargo concentration in the ER (Bos taurus)
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Gap junction trafficking and regulation (Bos taurus)
Gap junction trafficking (Bos taurus)
Gap junction assembly (Bos taurus)
Transport of connexons to the plasma membrane (Bos taurus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Bos taurus)
Association of Golgi transport vesicles with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-dependent Golgi-to-ER retrograde traffic (Bos taurus)
ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Active ARF recruits coatomer to the Golgi (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
COPI vesicle uncoating at the ER (Bos taurus)
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
GBF1 recruits ARF:GDP to the Golgi (Bos taurus)
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
GBF1 stimulates nucleotide exchange on ARF (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:ARF:GDP [Golgi membrane] (Bos taurus)
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB:GTP recruits GBF1 to the Golgi membrane (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Retrograde COPI vesicles bind kinesin and microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GTP [endoplasmic reticulum membrane] (Bos taurus)
RAB18:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:COPI-independent retrograde Golgi-to-ER cargo [endoplasmic reticulum membrane] (Bos taurus)
RAB6:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Bos taurus)
GTP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GTP [endoplasmic reticulum membrane] (Bos taurus)
RAB18:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Bos taurus)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Intra-Golgi traffic (Bos taurus)
RAB33B:GTP binds RIC1:RGP1 (Bos taurus)
RAB33B:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB33B:GTP:RIC1:RGP1 [Golgi membrane] (Bos taurus)
RAB33B:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
The COG complex binds RABs at the Golgi membrane (Bos taurus)
COG complex:RABs [Golgi membrane] (Bos taurus)
other COG-interacting RABs [Golgi membrane] (Bos taurus)
RAB30:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB36:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB39A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
other COG-interacting RABs [Golgi membrane] (Bos taurus)
RAB30:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB36:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB39A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Bos taurus)
ARFRP1 recruits ARL1 to the TGN (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARL1 recruits TGN Golgin homodimers (Bos taurus)
AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
ARL1:GTP binds ARFIP2 (Bos taurus)
ARFIP2:MyrG-ARL1:GTP [cytosol] (Bos taurus)
MyrG-ARL1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARL1:GTP binds SCOC (Bos taurus)
MyrG-ARL1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SCOC:MyrG-ARL1:GTP [cytosol] (Bos taurus)
MyrG-ARL1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Bos taurus)
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP [transport vesicle] (Bos taurus)
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3 [transport vesicle] (Bos taurus)
RAB9:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB9:GTP:p-RABEPK:VAMP3:late endosome-to-TGN cargo [transport vesicle] (Bos taurus)
RAB9:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Fusion of early-endosome derived vesicles at the TGN (Bos taurus)
AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Bos taurus)
AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Bos taurus)
RAB6:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
Fusion of late-endosome derived vesicles at the TGN (Bos taurus)
RAB9:GTP:p-RABEPK:VAMP3:STX16:STX10:VTI1A:GARP complex:GCC2 dimer:late-endosome-to-TGN cargo [trans-Golgi network membrane] (Bos taurus)
RAB9:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Bos taurus)
AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Bos taurus)
RAB6:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Bos taurus)
AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Bos taurus)
RAB6:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Bos taurus)
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3 [transport vesicle] (Bos taurus)
RAB9:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP [transport vesicle] (Bos taurus)
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3 [transport vesicle] (Bos taurus)
RAB9:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Bos taurus)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Bos taurus)
RAB6:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
SYS1 binds AcM-ARFRP1 (Bos taurus)
AcM-ARFRP1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Bos taurus)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Bos taurus)
RAB9:GTP:p-RABEPK:VAMP3:STX16:STX10:VTI1A:GARP complex:GCC2 dimer:late-endosome-to-TGN cargo [trans-Golgi network membrane] (Bos taurus)
RAB9:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB9:GTP:p-RABEPK:VAMP3:late endosome-to-TGN cargo [transport vesicle] (Bos taurus)
RAB9:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Rab regulation of trafficking (Bos taurus)
RAB GEFs exchange GTP for GDP on RABs (Bos taurus)
DENND1s exchange GTP for GDP on RAB35 (Bos taurus)
GTP [cytosol]
GGC-RAB35:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
DENND3 exchanges GTP for GDP on RAB12 (Bos taurus)
GTP [cytosol]
GGC-RAB12:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Bos taurus)
GTP [cytosol]
GGC-RAB10:GTP [cytoplasmic vesicle membrane] (Bos taurus)
GTP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Bos taurus)
GTP [cytosol]
GGC-RAB39:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Bos taurus)
GTP [cytosol]
GGC-RAB14:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Bos taurus)
GTP [cytosol]
RAB32,RAB38:GTP [melanosome membrane] (Bos taurus)
GTP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Bos taurus)
GTP [cytosol]
RAB27:GTP [melanosome membrane] (Bos taurus)
GGC-RAB27A:GTP [melanosome membrane] (Bos taurus)
GTP [cytosol]
GGC-RAB27B:GTP [melanosome membrane] (Bos taurus)
GTP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Bos taurus)
GTP [cytosol]
GGC-RAB7:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Bos taurus)
GTP [cytosol]
GGC-RAB13:GTP [cell junction] (Bos taurus)
GTP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Bos taurus)
GTP [cytosol]
GGC-RAB21:GTP [early endosome membrane] (Bos taurus)
GTP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Bos taurus)
GTP [cytosol]
GGC-RAB3A:GTP [secretory granule membrane] (Bos taurus)
GTP [cytosol]
RAB31 GEFs exchange GTP for GDP on RAB31 (Bos taurus)
GTP [cytosol]
GGC-RAB31:GTP [early endosome membrane] (Bos taurus)
GTP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Bos taurus)
GTP [cytosol]
GGC-RAB18:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Bos taurus)
GTP [cytosol]
GGC-RAB5:GTP [early endosome membrane] (Bos taurus)
GTP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Bos taurus)
GTP [cytosol]
GGC-RAB8:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)
GTP [cytosol]
GGC-RAB9:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Bos taurus)
GTP [cytosol]
GGC-RAB6:GTP [trans-Golgi network membrane] (Bos taurus)
GTP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Bos taurus)
GTP [cytosol]
GGC-RAB1:GTP [transport vesicle membrane] (Bos taurus)
GGC-RAB1A:GTP [transport vesicle membrane] (Bos taurus)
GTP [cytosol]
GGC-RAB1B:GTP [transport vesicle membrane] (Bos taurus)
GTP [cytosol]
TBC/RABGAPs (Bos taurus)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Bos taurus)
RAB35:GTP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
TBC1D10A (EPI64) binds ARF6:GTP (Bos taurus)
ARF6:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
TBC1D10A:ARF6:GTP [recycling endosome membrane] (Bos taurus)
ARF6:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
TBC1D11 binds RAB6 (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RABGAP1:RAB6:GTP [Golgi membrane] (Bos taurus)
RAB6:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
TBC1D17 binds OPTN:RAB8A (Bos taurus)
OPTN:RAB8:GTP [recycling endosome membrane] (Bos taurus)
RAB8:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
OPTN:RAB8:GTP:TBC1D17 [recycling endosome membrane] (Bos taurus)
OPTN:RAB8:GTP [recycling endosome membrane] (Bos taurus)
RAB8:GTP [recycling endosome membrane] (Bos taurus)
GTP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Bos taurus)
RAB33:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
trans-Golgi Network Vesicle Budding (Bos taurus)
Golgi Associated Vesicle Biogenesis (Bos taurus)
trans-Golgi Network Coat Assembly (Bos taurus)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Bos taurus)
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
trans-Golgi Network Vesicle Scission (Bos taurus)
GTP [cytosol]
Lysosome Vesicle Biogenesis (Bos taurus)
trans-Golgi Network Lysosomal Vesicle Scission (Bos taurus)
GTP [cytosol]
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Bos taurus)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Bos taurus)
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
trans-Golgi Network Coat Activation (Bos taurus)
GTP [cytosol]
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
Active MTORC1 binds the ULK1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
MTORC1 dissociates from ULK complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Metaphase and Anaphase (Caenorhabditis elegans)
Mitotic Anaphase (Caenorhabditis elegans)
Nuclear Envelope (NE) Reassembly (Caenorhabditis elegans)
Postmitotic nuclear pore complex (NPC) reformation (Caenorhabditis elegans)
RAN stimulates fusion of nuclear envelope (NE) membranes (Caenorhabditis elegans)
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Caenorhabditis elegans)
RAN:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAN:GTP recruits nuclear envelope (NE) membranes (Caenorhabditis elegans)
RAN:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Caenorhabditis elegans)
RAN:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Caenorhabditis elegans)
GTP [cytosol]
RAN:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Mitotic Prophase (Caenorhabditis elegans)
Golgi Cisternae Pericentriolar Stack Reorganization (Caenorhabditis elegans)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Caenorhabditis elegans)
GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Caenorhabditis elegans)
RAB2A:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Caenorhabditis elegans)
RAB2A:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
PLK1 phosphorylates GORASP1 (Caenorhabditis elegans)
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Caenorhabditis elegans)
p-RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Caenorhabditis elegans)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
p-RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to starvation (Caenorhabditis elegans)
Amino acids regulate mTORC1 (Caenorhabditis elegans)
RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGA,B hydrolyzes GTP (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GDP:RagC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGC:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGD:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGC,D hydrolyzes GTP (Caenorhabditis elegans)
RRAGC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGC:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGD:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GDP:RagC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGC,D:GTP [cytosol] (Caenorhabditis elegans)
RRAGC:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGD:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 binds RHEB:GTP (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
EPH-Ephrin signaling (Caenorhabditis elegans)
EPH-ephrin mediated repulsion of cells (Caenorhabditis elegans)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
EPHA-mediated growth cone collapse (Caenorhabditis elegans)
NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
EPHB-mediated forward signaling (Caenorhabditis elegans)
CDC42 and PIP2 bind WASL, activating it (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
KALRN exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
N-WASP binds ARP2/3 and G-actin (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK1 autophosphorylates (Caenorhabditis elegans)
RAC1-GTP:p-S144,T423-PAK1 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK1 binds RAC1:GTP (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP binds ROCK, activating it (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Caenorhabditis elegans)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Caenorhabditis elegans)
HRAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Ephrin signaling (Caenorhabditis elegans)
PAK binds RAC and bPIX (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAKs autophosphorylate (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAKs phosphorylate MLC (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Caenorhabditis elegans)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
bPIX exchanges GTP for GDP on RAC, activating it (Caenorhabditis elegans)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
L1CAM interactions (Caenorhabditis elegans)
Recycling pathway of L1 (Caenorhabditis elegans)
Formation of clathrin coated vesicle (Caenorhabditis elegans)
GTP [cytosol]
Signal transduction by L1 (Caenorhabditis elegans)
Activation of Rac1 by VAV2 (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Interaction of PAK1 with Rac1-GTP (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
pPAK1:Rac1-GTP [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
NCAM signaling for neurite out-growth (Caenorhabditis elegans)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Netrin-1 signaling (Caenorhabditis elegans)
DCC mediated attractive signaling (Caenorhabditis elegans)
Activation of Cdc42 (Caenorhabditis elegans)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of Rac1 (Caenorhabditis elegans)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Semaphorin interactions (Caenorhabditis elegans)
Sema3A PAK dependent Axon repulsion (Caenorhabditis elegans)
Activation of PAK by Rac1 (Caenorhabditis elegans)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Caenorhabditis elegans)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of PAK (Caenorhabditis elegans)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Caenorhabditis elegans)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Caenorhabditis elegans)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Sema4D in semaphorin signaling (Caenorhabditis elegans)
Sema4D induced cell migration and growth-cone collapse (Caenorhabditis elegans)
Activation of Rho by LARG and PDZ-RhoGEF (Caenorhabditis elegans)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ROCK activation by RHO (Caenorhabditis elegans)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Caenorhabditis elegans)
Active Rac1 interacts with Plexin-B1:Sema4D (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Caenorhabditis elegans)
R-Ras-GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Caenorhabditis elegans)
RND1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Inactivation of Rho-GTP by p190RhoGAP (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Caenorhabditis elegans)
RND1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p190RhoGAP binds Plexin-B1 (Caenorhabditis elegans)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Caenorhabditis elegans)
RND1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Caenorhabditis elegans)
RND1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by ROBO receptors (Caenorhabditis elegans)
SLIT2:ROBO1 increases RHOA activity (Caenorhabditis elegans)
MYO9B inactivates RHOA (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Hemostasis (Caenorhabditis elegans)
Factors involved in megakaryocyte development and platelet production (Caenorhabditis elegans)
Kinesins (Caenorhabditis elegans)
Kinesins move along microtubules consuming ATP (Caenorhabditis elegans)
Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
GPVI-mediated activation cascade (Caenorhabditis elegans)
VAV1 is a GEF for Rho/Rac family GTPases (Caenorhabditis elegans)
GTP [cytosol]
VAV1 Rho/Rac effectors:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
GTP [cytosol]
VAV2 Rho/Rac effectors:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)
GTP [cytosol]
VAV3 Rho/Rac effectors:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of Talin (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin alphaIIb beta3 activation (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Release of CSK from SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Caenorhabditis elegans)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Translocation of RIAM to plasma membrane (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signal amplification (Caenorhabditis elegans)
ADP signalling through P2Y purinoceptor 1 (Caenorhabditis elegans)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ADP signalling through P2Y purinoceptor 12 (Caenorhabditis elegans)
Gi activation by P2Y purinoceptor 12 (Caenorhabditis elegans)
GTP [cytosol]
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thromboxane signalling through TP receptor (Caenorhabditis elegans)
G13 activation by TP receptor (Caenorhabditis elegans)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Gq activation by TP receptor (Caenorhabditis elegans)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
G protein-GTP [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Caenorhabditis elegans)
Thrombin-activated PARs activate G12/13 (Caenorhabditis elegans)
GTP [cytosol]
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein G12/G13 (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thrombin-activated PARs activate Gq (Caenorhabditis elegans)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Caenorhabditis elegans)
G protein-GTP [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thrombin-activated PARs:G12/13 (active) dissociate (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein G12/G13 (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thrombin-activated PARs:Gq (active) dissociate (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Caenorhabditis elegans)
G protein-GTP [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Caenorhabditis elegans)
Coat Assembly (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rap1 signalling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rap1 sequesters Raf1 to inhibit ERK cascade (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rap1-GTP:Raf1 [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rap1 signal termination by Rap1GAPs (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Regulation of T cell activation by CD28 family (Caenorhabditis elegans)
Co-stimulation by CD28 (Caenorhabditis elegans)
CD28 dependent Vav1 pathway (Caenorhabditis elegans)
Activation of PAKs by RAC1 and CDC42 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by the B Cell Receptor (BCR) (Caenorhabditis elegans)
Downstream signaling events of B Cell Receptor (BCR) (Caenorhabditis elegans)
Activation of RAS in B cells (Caenorhabditis elegans)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Cytokine Signaling in Immune system (Caenorhabditis elegans)
FLT3 Signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Innate Immune System (Caenorhabditis elegans)
C-type lectin receptors (CLRs) (Caenorhabditis elegans)
CD209 (DC-SIGN) signaling (Caenorhabditis elegans)
PAK phosphorylates p21 RAF1 on S338 (Caenorhabditis elegans)
p21 RAS:GTP:RAF1 [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAF1 binds p21 RAS:GTP (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:RAF1 [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Caenorhabditis elegans)
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Caenorhabditis elegans)
Regulation of actin dynamics for phagocytic cup formation (Caenorhabditis elegans)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ABL phosphorylates WAVEs (Caenorhabditis elegans)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of PAK1 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Detachment of WASP/WAVE (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 and CDC42 activate PAK1 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Caenorhabditis elegans)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Metabolism (Caenorhabditis elegans)
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Adrenaline,noradrenaline inhibits insulin secretion (Caenorhabditis elegans)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Caenorhabditis elegans)
GTP [cytosol]
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Caenorhabditis elegans)
G-alpha(i,o):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Gi,Go Heterotrimeric G-protein complex dissociates (Caenorhabditis elegans)
G-alpha(i,o):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Caenorhabditis elegans)
G-alpha(i,o):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Caenorhabditis elegans)
RAP1A exchanges GDP for GTP (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PCK1 phosphorylates OA to yield PEP (Caenorhabditis elegans)
GTP [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Caenorhabditis elegans)
(d)NTP [cytosol]
GTP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Caenorhabditis elegans)
(d)NTP [cytosol]
GTP [cytosol]
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)
GTP [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of cofactors (Caenorhabditis elegans)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Caenorhabditis elegans)
GCH1 reduces GTP to dihydroneopterin triphosphate (Caenorhabditis elegans)
GTP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Molybdenum cofactor biosynthesis (Caenorhabditis elegans)
Cyclisation of GTP to precursor Z (Caenorhabditis elegans)
GTP [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
Synthesis of substrates in N-glycan biosythesis (Caenorhabditis elegans)
GDP-fucose biosynthesis (Caenorhabditis elegans)
FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Caenorhabditis elegans)
GTP [cytosol]
Synthesis of GDP-mannose (Caenorhabditis elegans)
GMPPB converts Mannose-1-phosphate to GDP-Mannose (Caenorhabditis elegans)
GTP [cytosol]
Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPI-mediated anterograde transport (Caenorhabditis elegans)
Active ARF recruits coatomer (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1 [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [transport vesicle] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1 [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [transport vesicle] (Caenorhabditis elegans)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
COPII-mediated vesicle transport (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Loss of SAR1B GTPase (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Caenorhabditis elegans)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D20 binds RAB1:GTP (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Caenorhabditis elegans)
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
Vesicle budding (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Cargo concentration in the ER (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Translation (Caenorhabditis elegans)
Eukaryotic Translation Elongation (Caenorhabditis elegans)
Peptide chain elongation (Caenorhabditis elegans)
GTP-binding activates eEF2 (Caenorhabditis elegans)
GTP [cytosol]
eEF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Eukaryotic Translation Initiation (Caenorhabditis elegans)
Cap-dependent Translation Initiation (Caenorhabditis elegans)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Caenorhabditis elegans)
Translation initiation complex formation (Caenorhabditis elegans)
Formation of translation initiation complexes containing mRNA that does not circularize (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
48S complex [cytosol] (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Formation of the ternary complex, and subsequently, the 43S complex (Caenorhabditis elegans)
De novo formation of eIF2:GTP (Caenorhabditis elegans)
GTP [cytosol]
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Formation of the 43S pre-initiation complex (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Caenorhabditis elegans)
GTP [cytosol]
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
GTP hydrolysis and joining of the 60S ribosomal subunit (Caenorhabditis elegans)
The 60S subunit joins the translation initiation complex (Caenorhabditis elegans)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Caenorhabditis elegans)
eIF5B:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
eIF5B:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
eIF5B:GTP is hydrolyzed and released (Caenorhabditis elegans)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Caenorhabditis elegans)
eIF5B:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Recycling of eIF2:GDP (Caenorhabditis elegans)
eIF2 activation (Caenorhabditis elegans)
GTP [cytosol]
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Ribosomal scanning and start codon recognition (Caenorhabditis elegans)
Ribosomal scanning (Caenorhabditis elegans)
48S complex [cytosol] (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Start codon recognition (Caenorhabditis elegans)
48S complex [cytosol] (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
L13a-mediated translational silencing of Ceruloplasmin expression (Caenorhabditis elegans)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Caenorhabditis elegans)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Caenorhabditis elegans)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Caenorhabditis elegans)
43S complex [cytosol] (Caenorhabditis elegans)
ternary complex [cytosol] (Caenorhabditis elegans)
eIF2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Eukaryotic Translation Termination (Caenorhabditis elegans)
N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Caenorhabditis elegans)
ETF1 dimer:eRF3:GTP [cytosol] (Caenorhabditis elegans)
eRF3:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Me-Q185-ETF1 dimer:eRF3:GTP [cytosol] (Caenorhabditis elegans)
eRF3:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
GABA receptor activation (Caenorhabditis elegans)
GABA B receptor activation (Caenorhabditis elegans)
Activation of GABAB receptors (Caenorhabditis elegans)
Adenylate cyclase inhibitory pathway (Caenorhabditis elegans)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Organelle biogenesis and maintenance (Caenorhabditis elegans)
Cilium Assembly (Caenorhabditis elegans)
Anchoring of the basal body to the plasma membrane (Caenorhabditis elegans)
RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Caenorhabditis elegans)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Cargo trafficking to the periciliary membrane (Caenorhabditis elegans)
BBSome-mediated cargo-targeting to cilium (Caenorhabditis elegans)
ARL6:GTP and the BBSome bind ciliary cargo (Caenorhabditis elegans)
ARL6:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Caenorhabditis elegans)
ARL6:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ARL6:GTP and the BBSome target cargo to the primary cilium (Caenorhabditis elegans)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Caenorhabditis elegans)
ARL6:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VxPx cargo-targeting to cilium (Caenorhabditis elegans)
Cargo-carrying vesicles bud from the TGN (Caenorhabditis elegans)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB3IP and RAB8A bind to the ciliary targeting complex (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
The exocyst complex binds to RAB3IP in the ciliary targeting complex (Caenorhabditis elegans)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Caenorhabditis elegans)
exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RAB11A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB8A:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Sensory Perception (Caenorhabditis elegans)
Visual phototransduction (Caenorhabditis elegans)
The phototransduction cascade (Caenorhabditis elegans)
Inactivation, recovery and regulation of the phototransduction cascade (Caenorhabditis elegans)
GUCYs converts GTP to cGMP (Caenorhabditis elegans)
GTP [cytosol]
Signal Transduction (Caenorhabditis elegans)
Death Receptor Signaling (Caenorhabditis elegans)
p75 NTR receptor-mediated signalling (Caenorhabditis elegans)
Cell death signalling via NRAGE, NRIF and NADE (Caenorhabditis elegans)
NRAGE signals death through JNK (Caenorhabditis elegans)
GTP-bound RAC contributes to JNK activation (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)
GTP [cytosol]
GEFs [cytosol] (Caenorhabditis elegans)
G13-activated p115-RhoGEF [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p75NTR regulates axonogenesis (Caenorhabditis elegans)
Axonal growth inhibition (RHOA activation) (Caenorhabditis elegans)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of Talin (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin alphaIIb beta3 activation (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Release of CSK from SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Caenorhabditis elegans)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Translocation of RIAM to plasma membrane (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
Negative regulation of the PI3K/AKT network (Caenorhabditis elegans)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Caenorhabditis elegans)
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
MAF1 translocates to the nucleus (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAC1,RAC2,RHOG activate PI3K (Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
Intrinsic nucleotide exchange on RAS (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MAP2K and MAPK activation (Caenorhabditis elegans)
Dissociation of RAS:RAF complex (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Dual mechanism MAP2K inhibitors bind MAP2Ks (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Dual mechanism MAPK inhibitors bind MAPKs (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MAP2Ks and MAPKs bind to the activated RAF complex (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Caenorhabditis elegans)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Negative regulation of MAPK pathway (Caenorhabditis elegans)
BRAP autoubiquitinates (Caenorhabditis elegans)
p21 RAS:GTP:BRAP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:ub-BRAP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
BRAP binds RAS:GTP (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:BRAP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PEBP1 binds activated RAF1 (Caenorhabditis elegans)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Caenorhabditis elegans)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PP2A dephosphorylates RAF1 (Caenorhabditis elegans)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PP5 dephosphorylates RAF1 S338 (Caenorhabditis elegans)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAF activation (Caenorhabditis elegans)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Caenorhabditis elegans)
S-GCC MRAS:GTP:SHOC2:PP1 [plasma membrane] (Caenorhabditis elegans)
S-GCC MRAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Raf dimer inhibitors bind RAF heterodimers (Caenorhabditis elegans)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS processing (Caenorhabditis elegans)
ARL2:GTP bind PDE6D on KRAS4B (Caenorhabditis elegans)
ARL2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Caenorhabditis elegans)
ARL2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
KRAS4B recycles to the plasma membrane (Caenorhabditis elegans)
ARL2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Caenorhabditis elegans)
ARL2:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAS:GTP binds PI3K (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP:PI3K [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS:GTP binds RAL GDS proteins (Caenorhabditis elegans)
S-Farn-Me-2xPalmS HRAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
S-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteins [plasma membrane] (Caenorhabditis elegans)
S-Farn-Me-2xPalmS HRAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MAPK6/MAPK4 signaling (Caenorhabditis elegans)
Activation of PAKs by RAC1 and CDC42 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophosphorylation of PAK1,2,3 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MTOR signalling (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Formation of active mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
GTP loading by Rheb (Caenorhabditis elegans)
GTP [cytosol]
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Rag dimer formation (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1-mediated signalling (Caenorhabditis elegans)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
RagA,B:GTP:RagC,D:GDP [cytosol] (Caenorhabditis elegans)
RRAGA, RRAGB:GTP [cytosol] (Caenorhabditis elegans)
RRAGA:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RRAGB:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (12/13) signalling events (Caenorhabditis elegans)
G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G13-activated p115-RhoGEF [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GEFs activate RhoA,B,C (Caenorhabditis elegans)
GTP [cytosol]
GEFs [cytosol] (Caenorhabditis elegans)
G13-activated p115-RhoGEF [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
LARG activation by G alpha 12/13 (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (12/13):LARG [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
LARG binds plexin B1 (Caenorhabditis elegans)
G-protein alpha (12/13):LARG [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12/13):LARG [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Caenorhabditis elegans)
GTP [cytosol]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Caenorhabditis elegans)
G-protein G12/G13 (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ROCK activation by RHO (Caenorhabditis elegans)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
The Ligand:GPCR:G12/13 complex dissociates (Caenorhabditis elegans)
G-protein alpha (12/13):GTP [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Caenorhabditis elegans)
G-protein G12/G13 (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (12):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p115-RhoGEF activation of RHOA (Caenorhabditis elegans)
GTP [cytosol]
G13-activated p115-RhoGEF [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (13):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (i) signalling events (Caenorhabditis elegans)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (i):GTP:RGS [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Caenorhabditis elegans)
G alpha (i):GTP:RGS [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (i):GTP:SRC-1 [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
GTP [cytosol]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Opioid Signalling (Caenorhabditis elegans)
G-protein activation (Caenorhabditis elegans)
G-protein alpha subunit is inactivated (Caenorhabditis elegans)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
The receptor:G-protein complex binds GTP (Caenorhabditis elegans)
GTP [cytosol]
Opioid:MOR:G protein-GTP complex [plasma membrane] (Caenorhabditis elegans)
G protein-GTP [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein mediated events (Caenorhabditis elegans)
Adenylate cyclase activating pathway (Caenorhabditis elegans)
Adenylate cyclase converts ATP into cyclic AMP (Caenorhabditis elegans)
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Galpha-olf:GTP binds to adenylate cyclase and activates it (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Adenylate cyclase inhibitory pathway (Caenorhabditis elegans)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Caenorhabditis elegans)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Caenorhabditis elegans)
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PLC beta mediated events (Caenorhabditis elegans)
Inactivation of PLC beta (Caenorhabditis elegans)
Activated PLC beta 1/4 [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PIP2 hydrolysis (Caenorhabditis elegans)
Activated PLC beta 1/4 [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Opsins act as GEFs for G alpha-t (Caenorhabditis elegans)
GTP [cytosol]
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Caenorhabditis elegans)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Caenorhabditis elegans)
G-alpha(t)-GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
G alpha (i): GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (q) signalling events (Caenorhabditis elegans)
Active G alpha (q) binds RGS proteins (Caenorhabditis elegans)
G alpha (q):GTP:RGS [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (q) binds to Trio family RhoGEFs (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (q) in G (q):RGS complex is inactivated (Caenorhabditis elegans)
G alpha (q):GTP:RGS [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (q) inhibits PI3K alpha (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (q/11):PI3K alpha [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRK2 sequesters activated Gq (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (q):GRK2 [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Caenorhabditis elegans)
EGFR Transactivation by Gastrin (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)
GTP [cytosol]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
G protein-GTP [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PLC-beta hydrolyses PIP2 to DAG and IP3 (Caenorhabditis elegans)
Activated PLC beta 1/4 [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PLC-beta:G-alpha(q/11):DAG:IP3 [plasma membrane] (Caenorhabditis elegans)
Activated PLC beta 1/4 [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PLC-beta:G-alpha(q/11):PIP2 [plasma membrane] (Caenorhabditis elegans)
Activated PLC beta 1/4 [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
G protein-GTP [plasma membrane] (Caenorhabditis elegans)
G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (s) signalling events (Caenorhabditis elegans)
Liganded Gs-activating GPCR acts as a GEF for Gs (Caenorhabditis elegans)
GTP [cytosol]
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Caenorhabditis elegans)
G alpha (s):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (z) signalling events (Caenorhabditis elegans)
Active G alpha (z) binds RGS proteins (Caenorhabditis elegans)
G alpha (z):GTP:RGS16,17,20 [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (z) in G alpha (z):RGS complex is inactivated (Caenorhabditis elegans)
G alpha (z):GTP:RGS16,17,20 [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G alpha (z) inhibits adenylate cyclase (Caenorhabditis elegans)
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Caenorhabditis elegans)
GTP [cytosol]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
The Ligand:GPCR:Gz complex dissociates (Caenorhabditis elegans)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein alpha (z):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein beta:gamma signalling (Caenorhabditis elegans)
G beta:gamma signalling through CDC42 (Caenorhabditis elegans)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Caenorhabditis elegans)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Caenorhabditis elegans)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by PTK6 (Caenorhabditis elegans)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Caenorhabditis elegans)
ARHGAP35 binds RHOA:GTP (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ARHGAP35 stimulates RHOA GTPase activity (Caenorhabditis elegans)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
Estrogen-stimulated signaling through PRKCZ (Caenorhabditis elegans)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Caenorhabditis elegans)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Caenorhabditis elegans)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by EGFR (Caenorhabditis elegans)
EGFR downregulation (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Caenorhabditis elegans)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Ub-Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP binds CBL:Beta-Pix (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CBL:Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Caenorhabditis elegans)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Caenorhabditis elegans)
Beta-Pix:CDC42:GTP [cytosol] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRB2 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC1 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by ERBB2 (Caenorhabditis elegans)
ERBB2 Regulates Cell Motility (Caenorhabditis elegans)
MEMO1 binds RHOA:GTP:DIAPH1 (Caenorhabditis elegans)
RHOA:GTP:DIAPH1 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP:DIAPH1 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
GRB2 events in ERBB2 signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by FGFR (Caenorhabditis elegans)
Signaling by FGFR1 (Caenorhabditis elegans)
Downstream signaling of activated FGFR1 (Caenorhabditis elegans)
FRS-mediated FGFR1 signaling (Caenorhabditis elegans)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC-mediated cascade:FGFR1 (Caenorhabditis elegans)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by FGFR2 (Caenorhabditis elegans)
Downstream signaling of activated FGFR2 (Caenorhabditis elegans)
FRS-mediated FGFR2 signaling (Caenorhabditis elegans)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC-mediated cascade:FGFR2 (Caenorhabditis elegans)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by FGFR3 (Caenorhabditis elegans)
Downstream signaling of activated FGFR3 (Caenorhabditis elegans)
FRS-mediated FGFR3 signaling (Caenorhabditis elegans)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC-mediated cascade:FGFR3 (Caenorhabditis elegans)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by FGFR4 (Caenorhabditis elegans)
Downstream signaling of activated FGFR4 (Caenorhabditis elegans)
FRS-mediated FGFR4 signaling (Caenorhabditis elegans)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SHC-mediated cascade:FGFR4 (Caenorhabditis elegans)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by MET (Caenorhabditis elegans)
MET activates RAS signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MET promotes cell motility (Caenorhabditis elegans)
MET activates RAP1 and RAC1 (Caenorhabditis elegans)
DOCK7 activates RAC1 (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAPGEF1 activates RAP1 (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
MET receptor recycling (Caenorhabditis elegans)
GGA3 associates with activated MET receptor (Caenorhabditis elegans)
ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Caenorhabditis elegans)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by NTRKs (Caenorhabditis elegans)
Signaling by NTRK1 (TRKA) (Caenorhabditis elegans)
Signalling to ERKs (Caenorhabditis elegans)
Prolonged ERK activation events (Caenorhabditis elegans)
Frs2-mediated activation (Caenorhabditis elegans)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Caenorhabditis elegans)
RAP1:GTP:B-Raf complex [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
Dissociation of phosphorylated MAP2Ks and MAPKs (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Caenorhabditis elegans)
RAP1:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signalling to RAS (Caenorhabditis elegans)
p38MAPK events (Caenorhabditis elegans)
Ral-GDS binds to Ras-GTP (Caenorhabditis elegans)
Ras-GTP:RalGDS complex [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by PDGF (Caenorhabditis elegans)
Downstream signal transduction (Caenorhabditis elegans)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by SCF-KIT (Caenorhabditis elegans)
Activation of RAC1 (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Caenorhabditis elegans)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
CDC42:GTP binds PAK2 (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
PAK2 dimer:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
FYN phosphorylates PAK2 (Caenorhabditis elegans)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK2 autophorylates (Caenorhabditis elegans)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
PAK2 dimer:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ROCK1,ROCK2 are activated (Caenorhabditis elegans)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Caenorhabditis elegans)
RHOA:GTP:Mg2+ [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
PAK1-3 autophosphorylates (Caenorhabditis elegans)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Caenorhabditis elegans)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PAK1-3 dimer disassociates (Caenorhabditis elegans)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Caenorhabditis elegans)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Caenorhabditis elegans)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 binds PAK1-3 (Caenorhabditis elegans)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Caenorhabditis elegans)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p38 MAPK activation by VEGFR (Caenorhabditis elegans)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
Miro GTPase Cycle (Caenorhabditis elegans)
RHOT1 GTPase cycle (Caenorhabditis elegans)
RHOT1 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)
RHOT1:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOT1:GTP:RHOT1 effectors [mitochondrial outer membrane] (Caenorhabditis elegans)
RHOT1:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOT1 hydrolyzes GTP (Caenorhabditis elegans)
RHOT1:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOT2 GTPase cycle (Caenorhabditis elegans)
RHOT2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)
RHOT1:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOT2:GTP:RHOT2 effectors [mitochondrial outer membrane] (Caenorhabditis elegans)
RHOT1:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOT2 hydrolyzes GTP (Caenorhabditis elegans)
RHOT1:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by Rho GTPases (Caenorhabditis elegans)
RHO GTPase Effectors (Caenorhabditis elegans)
RHO GTPases Activate Formins (Caenorhabditis elegans)
DAAM1 recruits GTP-bound RHOA (Caenorhabditis elegans)
RHOA:GTP:Mg2+ [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ppDVL:DAAM1:RHOA:GTP [cytosol] (Caenorhabditis elegans)
RHOA:GTP:Mg2+ [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
DIAPH1 binds RHOA:GTP (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:DIAPH1 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
FMNL2 binds CDC42:GTP (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP:FMNL2 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)
RHOB:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB:GTP:DIAPH1,DIAPH3 [endosome membrane] (Caenorhabditis elegans)
RHOB:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP recruits DAIPH2-3 to endosomes (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:DIAPH2-3 [endosome membrane] (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Caenorhabditis elegans)
RHOD:GTP:DIAPH2-3 [endosome membrane] (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:DIAPH2:SRC-1 [endosome membrane] (Caenorhabditis elegans)
RHOD:GTP:DIAPH2-3 [endosome membrane] (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Caenorhabditis elegans)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP:FMNL1 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP:FMNL1 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases Activate ROCKs (Caenorhabditis elegans)
ROCK activation by RHO (Caenorhabditis elegans)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases Activate Rhotekin and Rhophilins (Caenorhabditis elegans)
RHOA:GTP:RTKN binds LIN7B (Caenorhabditis elegans)
RHOA:GTP:RTKN [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:RTKN:LIN7B [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:RTKN binds TAX1BP3 (Caenorhabditis elegans)
RHOA:GTP:RTKN [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:RTKN:TAX1BP3 [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP:RTKN [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Caenorhabditis elegans)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
ABL phosphorylates WAVEs (Caenorhabditis elegans)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Detachment of WASP/WAVE (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Caenorhabditis elegans)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases activate IQGAPs (Caenorhabditis elegans)
GTP-bound RAC1 and CDC42 bind IQGAPs (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
IQGAPs bind CALM1 (Caenorhabditis elegans)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Caenorhabditis elegans)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
IQGAPs bind F-actin, which is inhibited by calmodulin (Caenorhabditis elegans)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Caenorhabditis elegans)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Caenorhabditis elegans)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases activate PAKs (Caenorhabditis elegans)
Autophosphorylation of PAK1,2,3 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 and CDC42 activate PAK1 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 and CDC42 activate PAK2 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 and CDC42 activate PAK3 (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP, RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases activate PKNs (Caenorhabditis elegans)
PDPK1 phosphorylates PKN1,2,3 (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Caenorhabditis elegans)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPases regulate CFTR trafficking (Caenorhabditis elegans)
RHOQ binds GOPC:CFTR (Caenorhabditis elegans)
RHOQ:GTP [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RHOQ:GTP [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Caenorhabditis elegans)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RHOQ:GTP [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ:GTP:GOPC:CFTR [plasma membrane] (Caenorhabditis elegans)
RHOQ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHO GTPase cycle (Caenorhabditis elegans)
CDC42 GTPase cycle (Caenorhabditis elegans)
CDC42 GAPs stimulate CDC42 GTPase activity (Caenorhabditis elegans)
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42 GEFs activate CDC42 (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42 translocates to the endoplasmic reticulum membrane (Caenorhabditis elegans)
CDC42:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 GTPase cycle (Caenorhabditis elegans)
RAC1 GAPs stimulate RAC1 GTPase activity (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 GEFs activate RAC1 (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 binds effectors at the plasma membrane (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1 translocates to the endoplasmic reticulum membrane (Caenorhabditis elegans)
RAC1:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 GTPase cycle (Caenorhabditis elegans)
RAC2 GAPs stimulate RAC2 GTPase activity (Caenorhabditis elegans)
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 GEFs activate RAC2 (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)
RAC2:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP:RAC2 mitochondrial effectors [mitochondrial outer membrane] (Caenorhabditis elegans)
RAC2:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 binds effectors at the plasma membrane (Caenorhabditis elegans)
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Caenorhabditis elegans)
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 translocates to the ER membrane (Caenorhabditis elegans)
RAC2:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 translocates to the mitochondrial membrane (Caenorhabditis elegans)
RAC2:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2 translocates to the phagocytic vesicle membrane (Caenorhabditis elegans)
RAC2:GTP [phagocytic vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC3 GTPase cycle (Caenorhabditis elegans)
RAC3 GAPs stimulate RAC3 GTPase activity (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC3 GEFs activate RAC3 (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC3 binds effectors at the plasma membrane (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Caenorhabditis elegans)
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC3 translocates to the endoplasmic reticulum membrane (Caenorhabditis elegans)
RAC1:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA GTPase cycle (Caenorhabditis elegans)
RHOA GAPs stimulate RHOA GTPase activity (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA GEFs activate RHOA (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Caenorhabditis elegans)
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP translocates to the ER membrane (Caenorhabditis elegans)
RHOA:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB GTPase cycle (Caenorhabditis elegans)
RHOB GAPs stimulate RHOB GTPase activity (Caenorhabditis elegans)
RHOB:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB GEFs activate RHOB (Caenorhabditis elegans)
GTP [cytosol]
RHOB:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOB:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Caenorhabditis elegans)
RHOB:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB binds effectors on endosomes (Caenorhabditis elegans)
RHOB:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB:GTP:RHOB endosome effectors [endosome membrane] (Caenorhabditis elegans)
RHOB:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB translocates to the endosome membrane (Caenorhabditis elegans)
RHOB:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOB:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD GTPase cycle (Caenorhabditis elegans)
RHOD GAPs stimulate RHOD GTPase activity (Caenorhabditis elegans)
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD auto-activates (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD binds effectors at the Golgi membrane (Caenorhabditis elegans)
RHOD:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:RHOD Golgi membrane effectors [Golgi membrane] (Caenorhabditis elegans)
RHOD:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD binds effectors at the endosome membrane (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:RHOD endosome effectors [endosome membrane] (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)
RHOD:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:RHOD mitochondrial outer membrane effectors [mitochondrial outer membrane] (Caenorhabditis elegans)
RHOD:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Caenorhabditis elegans)
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD translocates to the Golgi membrane (Caenorhabditis elegans)
RHOD:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD translocates to the mitochondrial outer membrane (Caenorhabditis elegans)
RHOD:GTP [mitochondrial outer membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP translocates to the endosome membrane (Caenorhabditis elegans)
RHOD:GTP [endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOF GTPase cycle (Caenorhabditis elegans)
RHOF GAPs stimulate RHOF GTPase activity (Caenorhabditis elegans)
RHOF:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOF auto-activates (Caenorhabditis elegans)
GTP [cytosol]
RHOF:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOF binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOF:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOF:GTP:RHOF effectors [plasma membrane] (Caenorhabditis elegans)
RHOF:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG GTPase cycle (Caenorhabditis elegans)
RHOG GAPs stimulate RHOG GTPase activity (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG GEFs activate RHOG (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG translocates to the ER membrane (Caenorhabditis elegans)
RHOG:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOH GTPase cycle (Caenorhabditis elegans)
GDIs bind RHOH (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOH:GTP:RHOH GDIs [cytosol] (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOH binds GTP (Caenorhabditis elegans)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOH binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOH:GTP:RHOH effectors [plasma membrane] (Caenorhabditis elegans)
RHOG:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOJ GTPase cycle (Caenorhabditis elegans)
RHOJ GAPs stimulate RHOJ GTPase activity (Caenorhabditis elegans)
RHOJ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOJ GEFs activate RHOJ (Caenorhabditis elegans)
GTP [cytosol]
RHOJ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ GTPase cycle (Caenorhabditis elegans)
RHOQ GAPs stimulate RHOQ GTPase activity (Caenorhabditis elegans)
RHOQ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ GEFs activate RHOQ (Caenorhabditis elegans)
GTP [cytosol]
RHOQ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ binds GOPC:CFTR (Caenorhabditis elegans)
RHOQ:GTP [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
RHOQ:GTP [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOQ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ:GTP:RHOQ effectors [plasma membrane] (Caenorhabditis elegans)
RHOQ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ translocates to the Golgi-associated vesicle membranes (Caenorhabditis elegans)
RHOQ:GTP [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOQ:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOU GTPase cycle (Caenorhabditis elegans)
RHOU auto-activates (Caenorhabditis elegans)
GTP [cytosol]
RHOU:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOU binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOU:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOU:GTP:RHOU effectors [plasma membrane] (Caenorhabditis elegans)
RHOU:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOV GTPase cycle (Caenorhabditis elegans)
RHOV binds GTP (Caenorhabditis elegans)
GTP [cytosol]
RHOV:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOV binds effectors at the plasma membrane (Caenorhabditis elegans)
RHOV:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
RHOV:GTP:RHOV effectors [plasma membrane] (Caenorhabditis elegans)
RHOV:GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
Ca2+ pathway (Caenorhabditis elegans)
G-protein subunits dissociate from WNT:FZD complex (Caenorhabditis elegans)
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (o/t2):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (o/t2):GTP [plasma membrane] (Caenorhabditis elegans)
GTP [cytosol]
PCP/CE pathway (Caenorhabditis elegans)
DAAM1 recruits GTP-bound RHOA (Caenorhabditis elegans)
RHOA:GTP:Mg2+ [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ppDVL:DAAM1:RHOA:GTP [cytosol] (Caenorhabditis elegans)
RHOA:GTP:Mg2+ [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ppDVL recruits RAC (Caenorhabditis elegans)
RAC:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
pp-DVL:RAC:GTP [plasma membrane] (Caenorhabditis elegans)
RAC:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
BAR domain proteins recruit dynamin (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
Endophilins recruit synaptojanins to the clathrin-coated pit (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
DNM:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPI-mediated anterograde transport (Caenorhabditis elegans)
Active ARF recruits coatomer (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1 [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [transport vesicle] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP:USO1 [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [transport vesicle] (Caenorhabditis elegans)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:USO1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
COPII-mediated vesicle transport (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Loss of SAR1B GTPase (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Nucleotide exchange on RAB1 (Caenorhabditis elegans)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Caenorhabditis elegans)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
SAR1 Activation And Membrane Binding (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D20 binds RAB1:GTP (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Caenorhabditis elegans)
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
GTP [cytosol]
Vesicle budding (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Cargo concentration in the ER (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
Golgi-to-ER retrograde transport (Caenorhabditis elegans)
COPI-dependent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Caenorhabditis elegans)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP:GBF1:ARF:GTP [Golgi membrane] (Caenorhabditis elegans)
ARF:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
COPI vesicle uncoating at the ER (Caenorhabditis elegans)
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
RAB1:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB:GTP recruits GBF1 to the Golgi membrane (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:GBF1 [Golgi membrane] (Caenorhabditis elegans)
RAB1:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)
Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [transport vesicle] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Caenorhabditis elegans)
Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Caenorhabditis elegans)
RAB1:GTP [transport vesicle] (Caenorhabditis elegans)
GTP [cytosol]
COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
RAB18:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:COPI-independent retrograde Golgi-to-ER cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
RAB6:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Caenorhabditis elegans)
GTP [cytosol]
RAB3GAP1:RAB3GAP2:RAB18:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
RAB18:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
Microtubule [cytosol] (Caenorhabditis elegans)
Microtubule protofilament [cytosol] (Caenorhabditis elegans)
alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
alpha-tubulin:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
Intra-Golgi traffic (Caenorhabditis elegans)
RAB33B:GTP binds RIC1:RGP1 (Caenorhabditis elegans)
RAB33B:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB33B:GTP:RIC1:RGP1 [Golgi membrane] (Caenorhabditis elegans)
RAB33B:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
The COG complex binds RABs at the Golgi membrane (Caenorhabditis elegans)
COG complex:RABs [Golgi membrane] (Caenorhabditis elegans)
other COG-interacting RABs [Golgi membrane] (Caenorhabditis elegans)
RAB30:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB39A:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB41:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
other COG-interacting RABs [Golgi membrane] (Caenorhabditis elegans)
RAB30:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB39A:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB41:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Caenorhabditis elegans)
ARFRP1 recruits ARL1 to the TGN (Caenorhabditis elegans)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ARL1 recruits TGN Golgin homodimers (Caenorhabditis elegans)
AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
MyrG-ARL1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
ARL1:GTP binds ARFIP2 (Caenorhabditis elegans)
ARFIP2:MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
ARL1:GTP binds SCOC (Caenorhabditis elegans)
MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
SCOC:MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
MyrG-ARL1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
RAB43 hydrolyses GTP (Caenorhabditis elegans)
RAB43:GTP:USP6NL [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB43:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB43:GTP binds USP8NL (Caenorhabditis elegans)
RAB43:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB43:GTP:USP6NL [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB43:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)
GTP [cytosol]
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Caenorhabditis elegans)
RAB6:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
SYS1 binds AcM-ARFRP1 (Caenorhabditis elegans)
AcM-ARFRP1:GTP [cytosol] (Caenorhabditis elegans)
GTP [cytosol]
AcM-ARFRP1:GTP:SYS1 [trans-Golgi network membrane] (Caenorhabditis elegans)
AcM-ARFRP1:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
Rab regulation of trafficking (Caenorhabditis elegans)
RAB GEFs exchange GTP for GDP on RABs (Caenorhabditis elegans)
DENND1s exchange GTP for GDP on RAB35 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB35:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
DENND4s exchange GTP for GDP on RAB10 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB10:GTP [cytoplasmic vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
DENND5A,B exchange GTP for GDP on RAB39 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB39:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
DENND6A,B exchange GTP for GDP on RAB14 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB14:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
MADD exchanges GTP for GDP on RAB27 (Caenorhabditis elegans)
GTP [cytosol]
RAB27:GTP [melanosome membrane] (Caenorhabditis elegans)
GGC-RAB27A:GTP [melanosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB27B:GTP [melanosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB7:GTP [lysosomal membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB13 GEFs exchange GTP for GDP on RAB13 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB13:GTP [cell junction] (Caenorhabditis elegans)
GTP [cytosol]
RAB21 GEFs exchange GTP for GDP on RAB21 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB21:GTP [early endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB3 GEFs exchange GTP for GDP on RAB3A (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB3A:GTP [secretory granule membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB18:GTP [endoplasmic reticulum membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB5 GEFs exchange GTP for GDP on RAB5 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB5:GTP [early endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
RAB8 GEFs exchange GTP for GDP on RAB8 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB8:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
RIC1-RGP1 exchanges GTP for GDP on RAB6 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB6:GTP [trans-Golgi network membrane] (Caenorhabditis elegans)
GTP [cytosol]
TRAPPC complexes exchange GTP for GDP on RAB1 (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB1:GTP [transport vesicle membrane] (Caenorhabditis elegans)
GGC-RAB1A:GTP [transport vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
GGC-RAB1B:GTP [transport vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC/RABGAPs (Caenorhabditis elegans)
TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Caenorhabditis elegans)
RAB35:GTP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D10A (EPI64) binds ARF6:GTP (Caenorhabditis elegans)
ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D10A:ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
ARF6:GTP [recycling endosome membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D11 binds RAB6 (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
RABGAP1:RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
RAB6:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
TBC1D25 accelerates GTP hydrolysis by RAB33B (Caenorhabditis elegans)
RAB33:GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
trans-Golgi Network Vesicle Budding (Caenorhabditis elegans)
Golgi Associated Vesicle Biogenesis (Caenorhabditis elegans)
trans-Golgi Network Coat Assembly (Caenorhabditis elegans)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Caenorhabditis elegans)
Arf1-GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
trans-Golgi Network Vesicle Scission (Caenorhabditis elegans)
GTP [cytosol]
Lysosome Vesicle Biogenesis (Caenorhabditis elegans)
trans-Golgi Network Lysosomal Vesicle Scission (Caenorhabditis elegans)
GTP [cytosol]
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Caenorhabditis elegans)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Caenorhabditis elegans)
Arf1-GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
trans-Golgi Network Coat Activation (Caenorhabditis elegans)
GTP [cytosol]
Arf1-GTP [Golgi membrane] (Caenorhabditis elegans)
GTP [cytosol]
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
Active MTORC1 binds the ULK1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Active MTORC1 phosphorylates ULK1 (Canis familiaris)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
MTORC1 dissociates from ULK complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Selective autophagy (Canis familiaris)
Aggrephagy (Canis familiaris)
Aggresome dissociates from dynein and microtubule (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
PolyUb-Misfolded proteins bind vimentin to form aggresome (Canis familiaris)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Nuclear Envelope (NE) Reassembly (Canis familiaris)
Postmitotic nuclear pore complex (NPC) reformation (Canis familiaris)
RAN stimulates fusion of nuclear envelope (NE) membranes (Canis familiaris)
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Canis familiaris)
RAN:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RAN:GTP recruits nuclear envelope (NE) membranes (Canis familiaris)
RAN:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Canis familiaris)
RAN:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Canis familiaris)
GTP [cytosol]
RAN:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Canis familiaris)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Separation of Sister Chromatids (Canis familiaris)
ESPL1 (Separase) cleaves centromeric cohesin (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Separation of sister chromatids (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Sister Centromere:Kinetochore:Microtubules [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Mitotic Prometaphase (Canis familiaris)
EML4 and NUDC in mitotic spindle formation (Canis familiaris)
EML4 binds to microtubules (Canis familiaris)
EML4 homotrimer:Microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
EML4 recruits NUDC to mitotic spindle (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Kinetochore capture of astral microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Recruitment of NuMA to mitotic centrosomes (Canis familiaris)
Association of NuMA with microtubules (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Kinetochore assembly (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Mitotic Prophase (Canis familiaris)
Golgi Cisternae Pericentriolar Stack Reorganization (Canis familiaris)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Canis familiaris)
GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Canis familiaris)
RAB2A:GTP [Golgi membrane] (Canis familiaris)
GTP [cytosol]
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Canis familiaris)
RAB2A:GTP [Golgi membrane] (Canis familiaris)
GTP [cytosol]
PLK1 phosphorylates GORASP1 (Canis familiaris)
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Canis familiaris)
p-RAB1:GTP [Golgi membrane] (Canis familiaris)
GTP [cytosol]
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Canis familiaris)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP [Golgi membrane] (Canis familiaris)
p-RAB1:GTP [Golgi membrane] (Canis familiaris)
GTP [cytosol]
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
Regulation of PLK1 Activity at G2/M Transition (Canis familiaris)
PLK1 phosphorylates OPTN (Canis familiaris)
OPTN:RAB8A:GTP [Golgi membrane] (Canis familiaris)
RAB8A:GTP [Golgi membrane] (Canis familiaris)
GTP [cytosol]
RAB8A:GTP [Golgi membrane] (Canis familiaris)
GTP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Canis familiaris)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Canis familiaris)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
GTSE1 binds microtubule lattice in interphase cells (Canis familiaris)
GTSE1:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to mechanical stimuli (Canis familiaris)
Response of endothelial cells to shear stress (Canis familiaris)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Canis familiaris)
ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (Canis familiaris)
GTP [cytosol]
ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Canis familiaris)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Canis familiaris)
G alpha (s):GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
Cellular responses to stress (Canis familiaris)
Cellular response to starvation (Canis familiaris)
Amino acids regulate mTORC1 (Canis familiaris)
RRAGA,B exchanges GDP for GTP (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGA,B hydrolyzes GTP (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGC,D exchanges GTP for GDP (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Canis familiaris)
RagA,B:GDP:RagC,D:GTP [cytosol] (Canis familiaris)
RRAGC,D:GTP [cytosol] (Canis familiaris)
RRAGC:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGD:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGC,D hydrolyzes GTP (Canis familiaris)
RRAGC,D:GTP [cytosol] (Canis familiaris)
RRAGC:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGD:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Canis familiaris)
RagA,B:GDP:RagC,D:GTP [cytosol] (Canis familiaris)
RRAGC,D:GTP [cytosol] (Canis familiaris)
RRAGC:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGD:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
mTORC1 binds RHEB:GTP (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
RHEB:GTP [lysosomal membrane] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
RagA,B:GTP:RagC,D:GDP [cytosol] (Canis familiaris)
RRAGA, RRAGB:GTP [cytosol] (Canis familiaris)
RRAGA:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
RRAGB:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Microtubule [cytosol] (Canis familiaris)
Microtubule protofilament [cytosol] (Canis familiaris)
alpha-beta tubulin dimer [cytosol] (Canis familiaris)
alpha-tubulin:GTP [cytosol] (Canis familiaris)
GTP [cytosol]
Developmental Biology (Canis familiaris)
Myogenesis (Canis familiaris)
Nuclear translocation of p38 MAPK (Canis familiaris)
ABL1:JLP:CDO complex [plasma membrane] (Canis familiaris)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Canis familiaris)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Canis familiaris)
CDC42:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Canis familiaris)
ABL1:JLP:CDO complex [plasma membrane] (Canis familiaris)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Canis familiaris)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Canis familiaris)
CDC42:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPH-ephrin mediated repulsion of cells (Canis familiaris)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
EPHA-mediated growth cone collapse (Canis familiaris)
NGEF exchanges GTP for GDP on RHOA (Canis familiaris)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
EPHB-mediated forward signaling (Canis familiaris)
CDC42 and PIP2 bind WASL, activating it (Canis familiaris)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Canis familiaris)
CDC42:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Canis familiaris)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Canis familiaris)
CDC42:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
KALRN exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
N-WASP binds ARP2/3 and G-actin (Canis familiaris)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Canis familiaris)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Canis familiaris)
CDC42:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Canis familiaris)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Canis familiaris)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Canis familiaris)
CDC42:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
PAK1 autophosphorylates (Canis familiaris)
RAC1-GTP:p-S144,T423-PAK1 [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
PAK1 binds RAC1:GTP (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
RHOA:GTP binds ROCK, activating it (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
Ras:GTP binds p120-RasGAP (Canis familiaris)
HRAS:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Canis familiaris)
HRAS:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Canis familiaris)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Canis familiaris)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Canis familiaris)
HRAS:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Canis familiaris)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
Ephrin signaling (Canis familiaris)
PAK binds RAC and bPIX (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
PAKs autophosphorylate (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
PAKs phosphorylate MLC (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
bPIX exchanges GTP for GDP on RAC, activating it (Canis familiaris)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
RAC1:GTP [plasma membrane] (Canis familiaris)
GTP [cytosol]
L1CAM interactions (Canis familiaris)
Recycling pathway of L1 (Canis familiaris)
Formation of clathrin coated vesicle (Canis familiaris)
![GTP [cytosol] icon](/icon/R-ICO-012805.svg){kind=icon}