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What is Reactome ?
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Statistics
Our Logo
License Agreement
Privacy Notice
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Table of Contents
DOIs
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CH2O [nucleoplasm]
Stable Identifier
R-ALL-29478
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
Methanal, formaldehyde, Oxomethane, Oxomethylene, Methylene oxide
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prophase (Bos taurus)
Condensation of Prophase Chromosomes (Bos taurus)
PHF8 demethylates histone H4K20me1 (Bos taurus)
CH2O [nucleoplasm]
Chromatin organization (Bos taurus)
Chromatin modifying enzymes (Bos taurus)
HDMs demethylate histones (Bos taurus)
JMJD6 demethylates Me2R3-histone H3 (Bos taurus)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Bos taurus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Bos taurus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Bos taurus)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Bos taurus)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Bos taurus)
CH2O [nucleoplasm]
DNA Repair (Bos taurus)
DNA Damage Reversal (Bos taurus)
Reversal of alkylation damage by DNA dioxygenases (Bos taurus)
RNA demethylases demethylate N6-methyladenosine RNA (Bos taurus)
CH2O [nucleoplasm]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Prophase (Caenorhabditis elegans)
Condensation of Prophase Chromosomes (Caenorhabditis elegans)
PHF8 demethylates histone H4K20me1 (Caenorhabditis elegans)
CH2O [nucleoplasm]
Chromatin organization (Caenorhabditis elegans)
Chromatin modifying enzymes (Caenorhabditis elegans)
HDMs demethylate histones (Caenorhabditis elegans)
JMJD6 demethylates Me2R3-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Caenorhabditis elegans)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Caenorhabditis elegans)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Caenorhabditis elegans)
CH2O [nucleoplasm]
Signal Transduction (Caenorhabditis elegans)
Signaling by Rho GTPases (Caenorhabditis elegans)
RHO GTPase Effectors (Caenorhabditis elegans)
RHO GTPases activate PKNs (Caenorhabditis elegans)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Caenorhabditis elegans)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Caenorhabditis elegans)
CH2O [nucleoplasm]
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Caenorhabditis elegans)
CH2O [nucleoplasm]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prophase (Canis familiaris)
Condensation of Prophase Chromosomes (Canis familiaris)
PHF8 demethylates histone H4K20me1 (Canis familiaris)
CH2O [nucleoplasm]
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
HDMs demethylate histones (Canis familiaris)
JMJD6 demethylates Me2R3-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Canis familiaris)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Canis familiaris)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Canis familiaris)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Canis familiaris)
CH2O [nucleoplasm]
DNA Repair (Canis familiaris)
DNA Damage Reversal (Canis familiaris)
Reversal of alkylation damage by DNA dioxygenases (Canis familiaris)
RNA demethylases demethylate N6-methyladenosine RNA (Canis familiaris)
CH2O [nucleoplasm]
Signal Transduction (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PKNs (Canis familiaris)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Canis familiaris)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
CH2O [nucleoplasm]
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Canis familiaris)
CH2O [nucleoplasm]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Prophase (Danio rerio)
Condensation of Prophase Chromosomes (Danio rerio)
PHF8 demethylates histone H4K20me1 (Danio rerio)
CH2O [nucleoplasm]
DNA Repair (Danio rerio)
DNA Damage Reversal (Danio rerio)
Reversal of alkylation damage by DNA dioxygenases (Danio rerio)
RNA demethylases demethylate N6-methyladenosine RNA (Danio rerio)
CH2O [nucleoplasm]
Signal Transduction (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases activate PKNs (Danio rerio)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Danio rerio)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Danio rerio)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Danio rerio)
CH2O [nucleoplasm]
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Danio rerio)
CH2O [nucleoplasm]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
M Phase (Dictyostelium discoideum)
Mitotic Prophase (Dictyostelium discoideum)
Condensation of Prophase Chromosomes (Dictyostelium discoideum)
PHF8 demethylates histone H4K20me1 (Dictyostelium discoideum)
CH2O [nucleoplasm]
Chromatin organization (Dictyostelium discoideum)
Chromatin modifying enzymes (Dictyostelium discoideum)
HDMs demethylate histones (Dictyostelium discoideum)
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Dictyostelium discoideum)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Dictyostelium discoideum)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Dictyostelium discoideum)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Dictyostelium discoideum)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Dictyostelium discoideum)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Dictyostelium discoideum)
CH2O [nucleoplasm]
Chromatin organization (Drosophila melanogaster)
Chromatin modifying enzymes (Drosophila melanogaster)
HDMs demethylate histones (Drosophila melanogaster)
JMJD6 demethylates Me2sR4-HIST1H4 (Drosophila melanogaster)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Drosophila melanogaster)
CH2O [nucleoplasm]
Signal Transduction (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Drosophila melanogaster)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
CH2O [nucleoplasm]
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Drosophila melanogaster)
CH2O [nucleoplasm]
Chromatin organization (Gallus gallus)
Chromatin modifying enzymes (Gallus gallus)
HDMs demethylate histones (Gallus gallus)
JMJD6 demethylates Me2sR4-HIST1H4 (Gallus gallus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Gallus gallus)
CH2O [nucleoplasm]
DNA Repair (Gallus gallus)
DNA Damage Reversal (Gallus gallus)
Reversal of alkylation damage by DNA dioxygenases (Gallus gallus)
RNA demethylases demethylate N6-methyladenosine RNA (Gallus gallus)
CH2O [nucleoplasm]
DNA replication and repair (Gallus gallus)
DNA repair (Gallus gallus)
DNA Damage Reversal (Gallus gallus)
Reversal of Alkylation Damage By DNA Dioxygenases (Gallus gallus)
CH2O [nucleoplasm]
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Condensation of Prophase Chromosomes (Homo sapiens)
PHF8 demethylates histone H4K20me1 (Homo sapiens)
CH2O [nucleoplasm]
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HDMs demethylate histones (Homo sapiens)
JMJD6 demethylates Me2R3-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Homo sapiens)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Homo sapiens)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Homo sapiens)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Homo sapiens)
CH2O [nucleoplasm]
DNA Repair (Homo sapiens)
DNA Damage Reversal (Homo sapiens)
Reversal of alkylation damage by DNA dioxygenases (Homo sapiens)
ALKBH2 mediated reversal of alkylation damage (Homo sapiens)
Oxidative demethylation of 1-meA damaged DNA by ALKBH2 (Homo sapiens)
CH2O [nucleoplasm]
Oxidative demethylation of 3-meC damaged DNA by ALKBH2 (Homo sapiens)
CH2O [nucleoplasm]
ALKBH3 mediated reversal of alkylation damage (Homo sapiens)
Oxidative demethylation of 1-meA damaged DNA By ALKBH3 (Homo sapiens)
CH2O [nucleoplasm]
Oxidative demethylation of 3-meC damaged DNA By ALKBH3 (Homo sapiens)
CH2O [nucleoplasm]
RNA demethylases demethylate N6-methyladenosine RNA (Homo sapiens)
CH2O [nucleoplasm]
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases activate PKNs (Homo sapiens)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Homo sapiens)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Homo sapiens)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Homo sapiens)
CH2O [nucleoplasm]
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Homo sapiens)
CH2O [nucleoplasm]
Chromatin organization (Mus musculus)
Chromatin modifying enzymes (Mus musculus)
HDMs demethylate histones (Mus musculus)
JMJD6 demethylates Me2R3-histone H3 (Mus musculus)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Mus musculus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Mus musculus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Mus musculus)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Mus musculus)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Mus musculus)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Mus musculus)
CH2O [nucleoplasm]
DNA Repair (Mus musculus)
DNA Damage Reversal (Mus musculus)
Reversal of alkylation damage by DNA dioxygenases (Mus musculus)
RNA demethylases demethylate N6-methyladenosine RNA (Mus musculus)
CH2O [nucleoplasm]
Cell Cycle (Plasmodium falciparum)
Cell Cycle, Mitotic (Plasmodium falciparum)
M Phase (Plasmodium falciparum)
Mitotic Prophase (Plasmodium falciparum)
Condensation of Prophase Chromosomes (Plasmodium falciparum)
PHF8 demethylates histone H4K20me1 (Plasmodium falciparum)
CH2O [nucleoplasm]
Chromatin organization (Plasmodium falciparum)
Chromatin modifying enzymes (Plasmodium falciparum)
HDMs demethylate histones (Plasmodium falciparum)
KDM5A-D demethylate Me2K5-histone H3 (Plasmodium falciparum)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Plasmodium falciparum)
CH2O [nucleoplasm]
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Prophase (Rattus norvegicus)
Condensation of Prophase Chromosomes (Rattus norvegicus)
PHF8 demethylates histone H4K20me1 (Rattus norvegicus)
CH2O [nucleoplasm]
Chromatin organization (Rattus norvegicus)
Chromatin modifying enzymes (Rattus norvegicus)
HDMs demethylate histones (Rattus norvegicus)
JMJD6 demethylates Me2R3-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Rattus norvegicus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Rattus norvegicus)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Rattus norvegicus)
CH2O [nucleoplasm]
DNA Repair (Rattus norvegicus)
DNA Damage Reversal (Rattus norvegicus)
Reversal of alkylation damage by DNA dioxygenases (Rattus norvegicus)
RNA demethylases demethylate N6-methyladenosine RNA (Rattus norvegicus)
CH2O [nucleoplasm]
Signal Transduction (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate PKNs (Rattus norvegicus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Rattus norvegicus)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Rattus norvegicus)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Rattus norvegicus)
CH2O [nucleoplasm]
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
M Phase (Saccharomyces cerevisiae)
Mitotic Prophase (Saccharomyces cerevisiae)
Condensation of Prophase Chromosomes (Saccharomyces cerevisiae)
PHF8 demethylates histone H4K20me1 (Saccharomyces cerevisiae)
CH2O [nucleoplasm]
Chromatin organization (Saccharomyces cerevisiae)
Chromatin modifying enzymes (Saccharomyces cerevisiae)
HDMs demethylate histones (Saccharomyces cerevisiae)
PHF8 demethylates MeK21-histone H4 (Saccharomyces cerevisiae)
CH2O [nucleoplasm]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Rho GTPases (Saccharomyces cerevisiae)
RHO GTPase Effectors (Saccharomyces cerevisiae)
RHO GTPases activate PKNs (Saccharomyces cerevisiae)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Saccharomyces cerevisiae)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Saccharomyces cerevisiae)
CH2O [nucleoplasm]
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
M Phase (Schizosaccharomyces pombe)
Mitotic Prophase (Schizosaccharomyces pombe)
Condensation of Prophase Chromosomes (Schizosaccharomyces pombe)
PHF8 demethylates histone H4K20me1 (Schizosaccharomyces pombe)
CH2O [nucleoplasm]
Chromatin organization (Schizosaccharomyces pombe)
Chromatin modifying enzymes (Schizosaccharomyces pombe)
HDMs demethylate histones (Schizosaccharomyces pombe)
PHF8 demethylates MeK21-histone H4 (Schizosaccharomyces pombe)
CH2O [nucleoplasm]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Rho GTPases (Schizosaccharomyces pombe)
RHO GTPase Effectors (Schizosaccharomyces pombe)
RHO GTPases activate PKNs (Schizosaccharomyces pombe)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Schizosaccharomyces pombe)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Schizosaccharomyces pombe)
CH2O [nucleoplasm]
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Prophase (Sus scrofa)
Condensation of Prophase Chromosomes (Sus scrofa)
PHF8 demethylates histone H4K20me1 (Sus scrofa)
CH2O [nucleoplasm]
Chromatin organization (Sus scrofa)
Chromatin modifying enzymes (Sus scrofa)
HDMs demethylate histones (Sus scrofa)
JMJD6 demethylates Me2R3-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
JMJD6 demethylates Me2sR4-HIST1H4 (Sus scrofa)
CH2O [nucleoplasm]
JMJD6 demethylates MeR3-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Sus scrofa)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate Me2K5-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM1A, KDM1B demethylate MeK5-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM5A-D demethylate Me2K5-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM5A-D demethylate Me3K5-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Sus scrofa)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Sus scrofa)
CH2O [nucleoplasm]
DNA Repair (Sus scrofa)
DNA Damage Reversal (Sus scrofa)
Reversal of alkylation damage by DNA dioxygenases (Sus scrofa)
RNA demethylases demethylate N6-methyladenosine RNA (Sus scrofa)
CH2O [nucleoplasm]
Cell Cycle (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Prophase (Xenopus tropicalis)
Condensation of Prophase Chromosomes (Xenopus tropicalis)
PHF8 demethylates histone H4K20me1 (Xenopus tropicalis)
CH2O [nucleoplasm]
Chromatin organization (Xenopus tropicalis)
Chromatin modifying enzymes (Xenopus tropicalis)
HDMs demethylate histones (Xenopus tropicalis)
JMJD6 demethylates Me2sR4-HIST1H4 (Xenopus tropicalis)
CH2O [nucleoplasm]
JMJD6 demethylates MeR4-HIST1H4 (Xenopus tropicalis)
CH2O [nucleoplasm]
PHF8 demethylates MeK21-histone H4 (Xenopus tropicalis)
CH2O [nucleoplasm]
DNA Repair (Xenopus tropicalis)
DNA Damage Reversal (Xenopus tropicalis)
Reversal of alkylation damage by DNA dioxygenases (Xenopus tropicalis)
RNA demethylases demethylate N6-methyladenosine RNA (Xenopus tropicalis)
CH2O [nucleoplasm]
Signal Transduction (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases activate PKNs (Xenopus tropicalis)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Xenopus tropicalis)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Xenopus tropicalis)
CH2O [nucleoplasm]
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Xenopus tropicalis)
CH2O [nucleoplasm]
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Xenopus tropicalis)
CH2O [nucleoplasm]
External Reference Information
External Reference
formaldehyde [ChEBI:16842]
Participant Of
output
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2R3-histone H3
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates Me2sR4-HIST1H4
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR3-histone H3
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
JMJD6 demethylates MeR4-HIST1H4
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate Me2K5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM1A, KDM1B demethylate MeK5-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me2K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM5A-D demethylate Me3K5-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3
Oxidative demethylation of 1-meA damaged DNA by ALKBH2
Oxidative demethylation of 1-meA damaged DNA By ALKBH3
Oxidative demethylation of 3-meC damaged DNA by ALKBH2
Oxidative demethylation of 3-meC damaged DNA By ALKBH3
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates histone H4K20me1
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
PHF8 demethylates MeK21-histone H4
Reversal of Alkylation Damage By DNA Dioxygenases
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
RNA demethylases demethylate N6-methyladenosine RNA
Other forms of this molecule
CH2O [cytosol]
CH2O [mitochondrial matrix]
CH2O [endoplasmic reticulum lumen]
Cross References
COMPOUND
C00067
PubChem Substance
8143624
HMDB Metabolite
HMDB0001426
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