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Ca2+ [nucleoplasm]
Stable Identifier
R-ALL-29496
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
Calcium, calcium(2+)
Icon
Locations in the PathwayBrowser for interactor UniProt:P80511 S100A12
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prophase (Bos taurus)
Nuclear Envelope Breakdown (Bos taurus)
Depolymerization of the Nuclear Lamina (Bos taurus)
DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)
Ca2+ [nucleoplasm]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Prophase (Caenorhabditis elegans)
Nuclear Envelope Breakdown (Caenorhabditis elegans)
Depolymerization of the Nuclear Lamina (Caenorhabditis elegans)
DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)
Ca2+ [nucleoplasm]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prophase (Canis familiaris)
Nuclear Envelope Breakdown (Canis familiaris)
Depolymerization of the Nuclear Lamina (Canis familiaris)
DAG and Ca+2 bind to PKC and tether it to membrane (Canis familiaris)
Ca2+ [nucleoplasm]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Prophase (Danio rerio)
Nuclear Envelope Breakdown (Danio rerio)
Depolymerization of the Nuclear Lamina (Danio rerio)
DAG and Ca+2 bind to PKC and tether it to membrane (Danio rerio)
Ca2+ [nucleoplasm]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
M Phase (Dictyostelium discoideum)
Mitotic Prophase (Dictyostelium discoideum)
Nuclear Envelope Breakdown (Dictyostelium discoideum)
Depolymerization of the Nuclear Lamina (Dictyostelium discoideum)
DAG and Ca+2 bind to PKC and tether it to membrane (Dictyostelium discoideum)
Ca2+ [nucleoplasm]
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Prophase (Drosophila melanogaster)
Nuclear Envelope Breakdown (Drosophila melanogaster)
Depolymerization of the Nuclear Lamina (Drosophila melanogaster)
DAG and Ca+2 bind to PKC and tether it to membrane (Drosophila melanogaster)
Ca2+ [nucleoplasm]
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Prophase (Gallus gallus)
Nuclear Envelope Breakdown (Gallus gallus)
Depolymerization of the Nuclear Lamina (Gallus gallus)
DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)
Ca2+ [nucleoplasm]
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Nuclear Envelope Breakdown (Homo sapiens)
Depolymerization of the Nuclear Lamina (Homo sapiens)
DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)
Ca2+ [nucleoplasm]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by NPAS4 (Homo sapiens)
Regulation of NPAS4 gene expression (Homo sapiens)
Regulation of NPAS4 gene transcription (Homo sapiens)
Ca2+ binds KCNIP3 (Homo sapiens)
Ca2+ [nucleoplasm]
KCNIP3 binds NPAS4 gene promoter (Homo sapiens)
Ca2+ [nucleoplasm]
NPAS4 gene transcription is repressed by KCNIP3 (Homo sapiens)
Ca2+ [nucleoplasm]
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Prophase (Mus musculus)
Nuclear Envelope Breakdown (Mus musculus)
Depolymerization of the Nuclear Lamina (Mus musculus)
DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)
Ca2+ [nucleoplasm]
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Prophase (Rattus norvegicus)
Nuclear Envelope Breakdown (Rattus norvegicus)
Depolymerization of the Nuclear Lamina (Rattus norvegicus)
DAG and Ca+2 bind to PKC and tether it to membrane (Rattus norvegicus)
Ca2+ [nucleoplasm]
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
M Phase (Saccharomyces cerevisiae)
Mitotic Prophase (Saccharomyces cerevisiae)
Nuclear Envelope Breakdown (Saccharomyces cerevisiae)
Depolymerization of the Nuclear Lamina (Saccharomyces cerevisiae)
DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)
Ca2+ [nucleoplasm]
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
M Phase (Schizosaccharomyces pombe)
Mitotic Prophase (Schizosaccharomyces pombe)
Nuclear Envelope Breakdown (Schizosaccharomyces pombe)
Depolymerization of the Nuclear Lamina (Schizosaccharomyces pombe)
DAG and Ca+2 bind to PKC and tether it to membrane (Schizosaccharomyces pombe)
Ca2+ [nucleoplasm]
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Prophase (Sus scrofa)
Nuclear Envelope Breakdown (Sus scrofa)
Depolymerization of the Nuclear Lamina (Sus scrofa)
DAG and Ca+2 bind to PKC and tether it to membrane (Sus scrofa)
Ca2+ [nucleoplasm]
Cell Cycle (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Prophase (Xenopus tropicalis)
Nuclear Envelope Breakdown (Xenopus tropicalis)
Depolymerization of the Nuclear Lamina (Xenopus tropicalis)
DAG and Ca+2 bind to PKC and tether it to membrane (Xenopus tropicalis)
Ca2+ [nucleoplasm]
External Reference Information
External Reference
calcium(2+) [ChEBI:29108]
Participates
as a component of
Kcnip3:2xCa2+:Mg2+ [nucleoplasm] (Mus musculus)
KCNIP3:2xCa2+:Mg2+ [nucleoplasm] (Homo sapiens)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Plasmodium falciparum)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Xenopus tropicalis)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Mus musculus)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Gallus gallus)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Bos taurus)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Dictyostelium discoideum)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Sus scrofa)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Canis familiaris)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Schizosaccharomyces pombe)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Drosophila melanogaster)
CALM1:4xCa2+ [nucleoplasm] (Homo sapiens)
CALM1:4xCa2+ [nucleoplasm] (Xenopus tropicalis)
CALM1:4xCa2+ [nucleoplasm] (Sus scrofa)
CALM1:4xCa2+ [nucleoplasm] (Schizosaccharomyces pombe)
CALM1:4xCa2+ [nucleoplasm] (Gallus gallus)
CALM1:4xCa2+ [nucleoplasm] (Drosophila melanogaster)
CALM1:4xCa2+ [nucleoplasm] (Dictyostelium discoideum)
CALM1:4xCa2+ [nucleoplasm] (Rattus norvegicus)
CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
CALM1:4xCa2+ [nucleoplasm] (Plasmodium falciparum)
Calmodulin:Calcium [nucleoplasm] (Mus musculus)
CALM1:4xCa2+ [nucleoplasm] (Canis familiaris)
CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
Calm1:4xCa2+ [nucleoplasm] (Rattus norvegicus)
Active Calmodulin [nucleoplasm] (Rattus norvegicus)
DAG:active PKC:Ca+2 [nuclear envelope] (Bos taurus)
DAG:active PKC:Ca+2 [nuclear envelope] (Homo sapiens)
DAG:active PKC:Ca+2 [nuclear envelope] (Rattus norvegicus)
DAG:active PKC:Ca+2 [nuclear envelope] (Danio rerio)
DAG:active PKC:Ca+2 [nuclear envelope] (Schizosaccharomyces pombe)
DAG:active PKC:Ca+2 [nuclear envelope] (Canis familiaris)
DAG:active PKC:Ca+2 [nuclear envelope] (Drosophila melanogaster)
DAG:active PKC:Ca+2 [nuclear envelope] (Saccharomyces cerevisiae)
DAG:active PKC:Ca+2 [nuclear envelope] (Mus musculus)
DAG:active PKC:Ca+2 [nuclear envelope] (Xenopus tropicalis)
DAG:active PKC:Ca+2 [nuclear envelope] (Gallus gallus)
DAG:active PKC:Ca+2 [nuclear envelope] (Sus scrofa)
DAG:active PKC:Ca+2 [nuclear envelope] (Caenorhabditis elegans)
DAG:active PKC:Ca+2 [nuclear envelope] (Dictyostelium discoideum)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Homo sapiens)
CaN alpha regulatory:Ca2+ [nucleoplasm] (Rattus norvegicus)
as an input of
Ca2+ binds Kcnip3 (Mus musculus)
Ca2+ binds KCNIP3 (Homo sapiens)
DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)
DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)
DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)
DAG and Ca+2 bind to PKC and tether it to membrane (Rattus norvegicus)
DAG and Ca+2 bind to PKC and tether it to membrane (Canis familiaris)
DAG and Ca+2 bind to PKC and tether it to membrane (Sus scrofa)
DAG and Ca+2 bind to PKC and tether it to membrane (Danio rerio)
DAG and Ca+2 bind to PKC and tether it to membrane (Xenopus tropicalis)
DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)
DAG and Ca+2 bind to PKC and tether it to membrane (Drosophila melanogaster)
DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)
DAG and Ca+2 bind to PKC and tether it to membrane (Dictyostelium discoideum)
DAG and Ca+2 bind to PKC and tether it to membrane (Schizosaccharomyces pombe)
DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)
This entity regulates
Negatively
Kcnip3 binds Npas4 gene promoter
(Mus musculus)
KCNIP3 binds NPAS4 gene promoter
(Homo sapiens)
Positively
NPAS4 gene transcription is repressed by KCNIP3
(Homo sapiens)
Other forms of this molecule
Ca2+ [platelet dense granule lumen]
Ca2+ [endosome membrane]
Ca2+ [sarcoplasmic reticulum lumen]
Ca2+ [mitochondrial intermembrane space]
Ca2+ [lysosomal lumen]
Ca2+ [endocytic vesicle lumen]
Ca2+ [endoplasmic reticulum-Golgi intermediate compartment]
Ca2+ [Golgi lumen]
Ca2+ [platelet dense tubular network lumen]
Ca2+ [platelet dense tubular network membrane]
Ca2+ [plasma membrane]
Ca2+ [secretory granule lumen]
Ca2+ [nuclear envelope]
Ca2+ [mitochondrial matrix]
Ca2+ [mitochondrial inner membrane]
Ca2+ [endoplasmic reticulum membrane]
Ca2+ [cytosol]
Ca2+ [extracellular region]
Ca2+ [endoplasmic reticulum lumen]
Cross References
COMPOUND
C00076
PubChem Substance
8145461
HMDB Metabolite
HMDB0000464
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![Ca2+ [nucleoplasm] icon](/icon/R-ICO-012501.svg){kind=icon}
