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Zn2+ [mitochondrial intermembrane space]
Stable Identifier
R-ALL-3777117
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial intermembrane space
Synonyms
Zn++, zinc(2+), Zinc ion, Zn(II)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Bos taurus)
SOD1 dimer [mitochondrial intermembrane space] (Bos taurus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Bos taurus)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Bos taurus)
OMA1 hydrolyzes YME1L1 (Bos taurus)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Bos taurus)
Mitochondrial biogenesis (Bos taurus)
Transcriptional activation of mitochondrial biogenesis (Bos taurus)
SIRT5 deacetylates Cytochrome C (Bos taurus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Bos taurus)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Caenorhabditis elegans)
SOD1 dimer [mitochondrial intermembrane space] (Caenorhabditis elegans)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Caenorhabditis elegans)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Canis familiaris)
SOD1 dimer [mitochondrial intermembrane space] (Canis familiaris)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Canis familiaris)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Canis familiaris)
OMA1 hydrolyzes YME1L1 (Canis familiaris)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Danio rerio)
SOD1 dimer [mitochondrial intermembrane space] (Danio rerio)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Danio rerio)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Danio rerio)
Mitochondrial biogenesis (Danio rerio)
Transcriptional activation of mitochondrial biogenesis (Danio rerio)
SIRT5 deacetylates Cytochrome C (Danio rerio)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Danio rerio)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Dictyostelium discoideum)
SOD1 dimer [mitochondrial intermembrane space] (Dictyostelium discoideum)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Dictyostelium discoideum)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Dictyostelium discoideum)
OMA1 hydrolyzes YME1L1 (Dictyostelium discoideum)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Dictyostelium discoideum)
Mitochondrial biogenesis (Dictyostelium discoideum)
Transcriptional activation of mitochondrial biogenesis (Dictyostelium discoideum)
SIRT5 deacetylates Cytochrome C (Dictyostelium discoideum)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Dictyostelium discoideum)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Detoxification of Reactive Oxygen Species (Drosophila melanogaster)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Drosophila melanogaster)
SOD1 dimer [mitochondrial intermembrane space] (Drosophila melanogaster)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Drosophila melanogaster)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Gallus gallus)
SOD1 dimer [mitochondrial intermembrane space] (Gallus gallus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Gallus gallus)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Gallus gallus)
OMA1 hydrolyzes YME1L1 (Gallus gallus)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Gallus gallus)
Mitochondrial biogenesis (Gallus gallus)
Transcriptional activation of mitochondrial biogenesis (Gallus gallus)
SIRT5 deacetylates Cytochrome C (Gallus gallus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Gallus gallus)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
CCS transfers Cu to SOD1 (mitochondrial) (Homo sapiens)
CCS dimer [mitochondrial intermembrane space] (Homo sapiens)
CCS:Zn2+:Cu1+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
CCS:SOD1 dimer [mitochondrial intermembrane space] (Homo sapiens)
CCS:Zn2+:2Cu1+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
SOD1:Zn2+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
SOD1 dimer [mitochondrial intermembrane space] (Homo sapiens)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Homo sapiens)
SOD1 dimer [mitochondrial intermembrane space] (Homo sapiens)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
SOD1:Zn2+ apoenzyme binds CCS:Cu1+ (mitochondrial) (Homo sapiens)
CCS:Cu1+ dimer [mitochondrial intermembrane space] (Homo sapiens)
CCS:Zn2+:2Cu1+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
CCS:SOD1 dimer [mitochondrial intermembrane space] (Homo sapiens)
CCS:Zn2+:2Cu1+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
SOD1:Zn2+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
SOD1:Zn2+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Homo sapiens)
OMA1 hydrolyzes YME1L1 (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
SIRT5 deacetylates Cytochrome C (Homo sapiens)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Homo sapiens)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Mus musculus)
SOD1 dimer [mitochondrial intermembrane space] (Mus musculus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Mus musculus)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Mus musculus)
OMA1 hydrolyzes YME1L1 (Mus musculus)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Mus musculus)
Mitochondrial biogenesis (Mus musculus)
Transcriptional activation of mitochondrial biogenesis (Mus musculus)
SIRT5 deacetylates Cytochrome C (Mus musculus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Mus musculus)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Plasmodium falciparum)
Mitochondrial biogenesis (Plasmodium falciparum)
Transcriptional activation of mitochondrial biogenesis (Plasmodium falciparum)
SIRT5 deacetylates Cytochrome C (Plasmodium falciparum)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Plasmodium falciparum)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Rattus norvegicus)
SOD1 dimer [mitochondrial intermembrane space] (Rattus norvegicus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Rattus norvegicus)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Rattus norvegicus)
OMA1 hydrolyzes YME1L1 (Rattus norvegicus)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Rattus norvegicus)
Mitochondrial biogenesis (Rattus norvegicus)
Transcriptional activation of mitochondrial biogenesis (Rattus norvegicus)
SIRT5 deacetylates Cytochrome C (Rattus norvegicus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Rattus norvegicus)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Saccharomyces cerevisiae)
SOD1 dimer [mitochondrial intermembrane space] (Saccharomyces cerevisiae)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Saccharomyces cerevisiae)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Saccharomyces cerevisiae)
OMA1 hydrolyzes YME1L1 (Saccharomyces cerevisiae)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Schizosaccharomyces pombe)
SOD1 dimer [mitochondrial intermembrane space] (Schizosaccharomyces pombe)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Schizosaccharomyces pombe)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Schizosaccharomyces pombe)
OMA1 hydrolyzes YME1L1 (Schizosaccharomyces pombe)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Sus scrofa)
SOD1 dimer [mitochondrial intermembrane space] (Sus scrofa)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Sus scrofa)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Sus scrofa)
Mitochondrial biogenesis (Sus scrofa)
Transcriptional activation of mitochondrial biogenesis (Sus scrofa)
SIRT5 deacetylates Cytochrome C (Sus scrofa)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Sus scrofa)
Zn2+ [mitochondrial intermembrane space]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Xenopus tropicalis)
SOD1 dimer [mitochondrial intermembrane space] (Xenopus tropicalis)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Xenopus tropicalis)
Zn2+ [mitochondrial intermembrane space]
Cellular response to mitochondrial stress (Xenopus tropicalis)
OMA1 hydrolyzes YME1L1 (Xenopus tropicalis)
Zn2+ [mitochondrial intermembrane space]
Organelle biogenesis and maintenance (Xenopus tropicalis)
Mitochondrial biogenesis (Xenopus tropicalis)
Transcriptional activation of mitochondrial biogenesis (Xenopus tropicalis)
SIRT5 deacetylates Cytochrome C (Xenopus tropicalis)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Xenopus tropicalis)
Zn2+ [mitochondrial intermembrane space]
External Reference Information
External Reference
zinc(2+) [ChEBI:29105]
Participates
as a component of
SIRT5:Zn2+ [mitochondrial intermembrane space] (Mus musculus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Bos taurus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Rattus norvegicus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Sus scrofa)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Danio rerio)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Plasmodium falciparum)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Gallus gallus)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Xenopus tropicalis)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Dictyostelium discoideum)
SIRT5:Zn2+ [mitochondrial intermembrane space] (Homo sapiens)
Ccs:Zn2+:Cu1+ [mitochondrial intermembrane space] (Mus musculus)
2xHC-Sod1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Mus musculus)
Ccs:Zn2+:2Cu1+ [mitochondrial intermembrane space] (Mus musculus)
Sod1:Zn2+ [mitochondrial intermembrane space] (Mus musculus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Dictyostelium discoideum)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Drosophila melanogaster)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Xenopus tropicalis)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Bos taurus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Danio rerio)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Canis familiaris)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Saccharomyces cerevisiae)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Mus musculus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Gallus gallus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Caenorhabditis elegans)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Rattus norvegicus)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Schizosaccharomyces pombe)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Sus scrofa)
SOD1:Zn2+:Cu2+ [mitochondrial intermembrane space] (Homo sapiens)
CCS:Zn2+:Cu1+ [mitochondrial intermembrane space] (Homo sapiens)
CCS:Zn2+:2Cu1+ [mitochondrial intermembrane space] (Homo sapiens)
SOD1:Zn2+ [mitochondrial intermembrane space] (Homo sapiens)
as an output of
OMA1 hydrolyzes YME1L1 (Saccharomyces cerevisiae)
OMA1 hydrolyzes YME1L1 (Schizosaccharomyces pombe)
OMA1 hydrolyzes YME1L1 (Dictyostelium discoideum)
OMA1 hydrolyzes YME1L1 (Gallus gallus)
OMA1 hydrolyzes YME1L1 (Xenopus tropicalis)
OMA1 hydrolyzes YME1L1 (Bos taurus)
OMA1 hydrolyzes YME1L1 (Canis familiaris)
OMA1 hydrolyzes YME1L1 (Rattus norvegicus)
OMA1 hydrolyzes YME1L1 (Mus musculus)
OMA1 hydrolyzes YME1L1 (Homo sapiens)
Other forms of this molecule
Zn2+ [endocytic vesicle membrane]
Zn2+ [clathrin-coated endocytic vesicle membrane]
Zn2+ [synaptic vesicle membrane]
Zn2+ [endosome membrane]
Zn2+ [synaptic vesicle]
Zn2+ [secretory granule lumen]
Zn2+ [endosome lumen]
Zn2+ [endoplasmic reticulum lumen]
Zn2+ [Golgi membrane]
Zn2+ [phagocytic vesicle lumen]
Zn2+ [lysosomal lumen]
Zn2+ [Golgi lumen]
Zn2+ [mitochondrial matrix]
Zn2+ [melanosome membrane]
Zn2+ [endoplasmic reticulum membrane]
Zn2+ [mitochondrial inner membrane]
Zn2+ [extracellular region]
Zn2+ [cytosol]
Zn2+ [plasma membrane]
Zn2+ [nucleoplasm]
Cross References
COMPOUND
C00038
PubChem Substance
11533263
HMDB Metabolite
HMDB0015532
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