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ADR, NAd [extracellular region]
Stable Identifier
R-ALL-390627
Type
Set [DefinedSet]
Compartment
extracellular region
Synonyms
Catecholamine, adrenaline or noradrenaline
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
Platelet Aggregation (Plug Formation) (Bos taurus)
Adrenaline signalling through Alpha-2 adrenergic receptor (Bos taurus)
ADRA2A,B,C bind ADR,NAd (Bos taurus)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
ADRA2A,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Bos taurus)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Metabolism of proteins (Bos taurus)
Surfactant metabolism (Bos taurus)
SFTPB,C, PC, PG translocate from lamellar body to extracellular region (Bos taurus)
ADRA2A,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Bos taurus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Bos taurus)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Bos taurus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Bos taurus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Bos taurus)
ADRB2:Catecholamine:GRK [plasma membrane] (Bos taurus)
ADRB2:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB2:Catecholamine binds ARRB1, ARRB2 (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
GRKs bind ADRB2:Catecholamine (Bos taurus)
ADRB2:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB2:Catecholamine:GRK [plasma membrane] (Bos taurus)
ADRB2:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Bos taurus)
ADRB1:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Bos taurus)
ADRB1:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Bos taurus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gz complex dissociates (Bos taurus)
ADR, NAd [extracellular region]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Amine ligand-binding receptors (Bos taurus)
Adrenoceptors (Bos taurus)
ADRA1A,B,D bind ADR,NAd (Bos taurus)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Bos taurus)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB1 bind ADR,NAd (Bos taurus)
ADR, NAd [extracellular region]
ADRB1:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Bos taurus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ADRB3 bind ADR,NAd (Bos taurus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Clathrin-mediated endocytosis (Bos taurus)
BAR domain proteins recruit dynamin (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Cargo recognition for clathrin-mediated endocytosis (Bos taurus)
ARBB recruits GPCRs into clathrin-coated pits (Bos taurus)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ARRB bind GPCRs (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Clathrin recruits PIK3C2A (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Endophilins recruit synaptojanins to the clathrin-coated pit (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
F- and N- BAR domain proteins bind the clathrin-coated pit (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
SNX9 recruits components of the actin polymerizing machinery (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Bos taurus)
ARRB-binding GPCRs [plasma membrane] (Bos taurus)
pS-ADRB2:Catecholamine [plasma membrane] (Bos taurus)
ADR, NAd [extracellular region]
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Adrenaline signalling through Alpha-2 adrenergic receptor (Caenorhabditis elegans)
ADRA2A,B,C bind ADR,NAd (Caenorhabditis elegans)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Metabolism (Caenorhabditis elegans)
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Adrenaline,noradrenaline inhibits insulin secretion (Caenorhabditis elegans)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Caenorhabditis elegans)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (12/13) signalling events (Caenorhabditis elegans)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Caenorhabditis elegans)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Caenorhabditis elegans)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Caenorhabditis elegans)
Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Caenorhabditis elegans)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Caenorhabditis elegans)
Liganded Gz-activating GPCR acts as a GEF for Gz (Caenorhabditis elegans)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gz complex dissociates (Caenorhabditis elegans)
ADR, NAd [extracellular region]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Caenorhabditis elegans)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
GPCR ligand binding (Caenorhabditis elegans)
Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
Amine ligand-binding receptors (Caenorhabditis elegans)
Adrenoceptors (Caenorhabditis elegans)
ADRA1A,B,D bind ADR,NAd (Caenorhabditis elegans)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Caenorhabditis elegans)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)
ADR, NAd [extracellular region]
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Platelet Aggregation (Plug Formation) (Canis familiaris)
Adrenaline signalling through Alpha-2 adrenergic receptor (Canis familiaris)
ADRA2A,B,C bind ADR,NAd (Canis familiaris)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Metabolism (Canis familiaris)
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Adrenaline,noradrenaline inhibits insulin secretion (Canis familiaris)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Canis familiaris)
ADRA2A,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Canis familiaris)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Metabolism of proteins (Canis familiaris)
Surfactant metabolism (Canis familiaris)
SFTPB,C, PC, PG translocate from lamellar body to extracellular region (Canis familiaris)
ADRA2A,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (12/13) signalling events (Canis familiaris)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Canis familiaris)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Canis familiaris)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Canis familiaris)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Canis familiaris)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Canis familiaris)
ADRB2 in ADRB2:GRK complex is phosphorylated (Canis familiaris)
ADRB2:Catecholamine:GRK [plasma membrane] (Canis familiaris)
ADRB2:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ADRB2:Catecholamine binds ARRB1, ARRB2 (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
GRKs bind ADRB2:Catecholamine (Canis familiaris)
ADRB2:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ADRB2:Catecholamine:GRK [plasma membrane] (Canis familiaris)
ADRB2:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Canis familiaris)
Liganded Gz-activating GPCR acts as a GEF for Gz (Canis familiaris)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gz complex dissociates (Canis familiaris)
ADR, NAd [extracellular region]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Canis familiaris)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Amine ligand-binding receptors (Canis familiaris)
Adrenoceptors (Canis familiaris)
ADRA1A,B,D bind ADR,NAd (Canis familiaris)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Canis familiaris)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Canis familiaris)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ADRB3 bind ADR,NAd (Canis familiaris)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
BAR domain proteins recruit dynamin (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Cargo recognition for clathrin-mediated endocytosis (Canis familiaris)
ARBB recruits GPCRs into clathrin-coated pits (Canis familiaris)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ARRB bind GPCRs (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Clathrin recruits PIK3C2A (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Endophilins recruit synaptojanins to the clathrin-coated pit (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
F- and N- BAR domain proteins bind the clathrin-coated pit (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
SNX9 recruits components of the actin polymerizing machinery (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
pS-ADRB2:Catecholamine [plasma membrane] (Canis familiaris)
ADR, NAd [extracellular region]
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Platelet Aggregation (Plug Formation) (Danio rerio)
Adrenaline signalling through Alpha-2 adrenergic receptor (Danio rerio)
ADRA2A,B,C bind ADR,NAd (Danio rerio)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Metabolism (Danio rerio)
Integration of energy metabolism (Danio rerio)
Regulation of insulin secretion (Danio rerio)
Adrenaline,noradrenaline inhibits insulin secretion (Danio rerio)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Danio rerio)
ADRA2A,C:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Danio rerio)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (12/13) signalling events (Danio rerio)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Danio rerio)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Danio rerio)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Danio rerio)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Danio rerio)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Danio rerio)
ADRB2:Catecholamine binds ARRB1, ARRB2 (Danio rerio)
pS-ADRB2:Catecholamine [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Danio rerio)
pS-ADRB2:Catecholamine [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
Amine ligand-binding receptors (Danio rerio)
Adrenoceptors (Danio rerio)
ADRA1A,B,D bind ADR,NAd (Danio rerio)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Danio rerio)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
ADRB1 bind ADR,NAd (Danio rerio)
ADR, NAd [extracellular region]
ADRB1:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Danio rerio)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Vesicle-mediated transport (Danio rerio)
Membrane Trafficking (Danio rerio)
Clathrin-mediated endocytosis (Danio rerio)
Cargo recognition for clathrin-mediated endocytosis (Danio rerio)
ARRB bind GPCRs (Danio rerio)
ARRB-binding GPCRs [plasma membrane] (Danio rerio)
pS-ADRB2:Catecholamine [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Danio rerio)
ARRB-binding GPCRs [plasma membrane] (Danio rerio)
pS-ADRB2:Catecholamine [plasma membrane] (Danio rerio)
ADR, NAd [extracellular region]
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Adrenaline signalling through Alpha-2 adrenergic receptor (Drosophila melanogaster)
ADRA2A,B,C bind ADR,NAd (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Metabolism (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Adrenaline,noradrenaline inhibits insulin secretion (Drosophila melanogaster)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Drosophila melanogaster)
ADRA2A,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Drosophila melanogaster)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Drosophila melanogaster)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Drosophila melanogaster)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Drosophila melanogaster)
Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Drosophila melanogaster)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Drosophila melanogaster)
ADRB2 in ADRB2:GRK complex is phosphorylated (Drosophila melanogaster)
ADRB2:Catecholamine:GRK [plasma membrane] (Drosophila melanogaster)
ADRB2:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2:Catecholamine binds ARRB1, ARRB2 (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
GRKs bind ADRB2:Catecholamine (Drosophila melanogaster)
ADRB2:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2:Catecholamine:GRK [plasma membrane] (Drosophila melanogaster)
ADRB2:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Liganded Gs-activating GPCR acts as a GEF for Gs (Drosophila melanogaster)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Drosophila melanogaster)
ADRB1:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Drosophila melanogaster)
ADRB1:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Drosophila melanogaster)
Liganded Gz-activating GPCR acts as a GEF for Gz (Drosophila melanogaster)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Drosophila melanogaster)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
GPCR ligand binding (Drosophila melanogaster)
Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
Amine ligand-binding receptors (Drosophila melanogaster)
Adrenoceptors (Drosophila melanogaster)
ADRA1A,B,D bind ADR,NAd (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB1 bind ADR,NAd (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB1:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB3 bind ADR,NAd (Drosophila melanogaster)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
ARBB recruits GPCRs into clathrin-coated pits (Drosophila melanogaster)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ARRB bind GPCRs (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Clathrin recruits PIK3C2A (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine [plasma membrane] (Drosophila melanogaster)
ADR, NAd [extracellular region]
Hemostasis (Gallus gallus)
Platelet activation, signaling and aggregation (Gallus gallus)
Platelet Aggregation (Plug Formation) (Gallus gallus)
Adrenaline signalling through Alpha-2 adrenergic receptor (Gallus gallus)
ADRA2A,B,C bind ADR,NAd (Gallus gallus)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Metabolism (Gallus gallus)
Integration of energy metabolism (Gallus gallus)
Regulation of insulin secretion (Gallus gallus)
Adrenaline,noradrenaline inhibits insulin secretion (Gallus gallus)
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Gallus gallus)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Metabolism of proteins (Gallus gallus)
Surfactant metabolism (Gallus gallus)
SFTPB,C, PC, PG translocate from lamellar body to extracellular region (Gallus gallus)
ADRA2A,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (12/13) signalling events (Gallus gallus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Gallus gallus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Gallus gallus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Gallus gallus)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Gallus gallus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Gallus gallus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Gallus gallus)
ADRB2:Catecholamine:GRK [plasma membrane] (Gallus gallus)
ADRB2:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Gallus gallus)
pS-ADRB2:Catecholamine [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
GRKs bind ADRB2:Catecholamine (Gallus gallus)
ADRB2:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB2:Catecholamine:GRK [plasma membrane] (Gallus gallus)
ADRB2:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Liganded Gs-activating GPCR acts as a GEF for Gs (Gallus gallus)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Gallus gallus)
ADRB1:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Gallus gallus)
ADRB1:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Gallus gallus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Gallus gallus)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gz complex dissociates (Gallus gallus)
ADR, NAd [extracellular region]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Gallus gallus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Amine ligand-binding receptors (Gallus gallus)
Adrenoceptors (Gallus gallus)
ADRA1A,B,D bind ADR,NAd (Gallus gallus)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Gallus gallus)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB1 bind ADR,NAd (Gallus gallus)
ADR, NAd [extracellular region]
ADRB1:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Gallus gallus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
ADRB3 bind ADR,NAd (Gallus gallus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Gallus gallus)
ADR, NAd [extracellular region]
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Platelet Aggregation (Plug Formation) (Homo sapiens)
Adrenaline signalling through Alpha-2 adrenergic receptor (Homo sapiens)
ADRA2A,B,C bind ADR,NAd (Homo sapiens)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Adrenaline,noradrenaline inhibits insulin secretion (Homo sapiens)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Homo sapiens)
ADRA2A,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Homo sapiens)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
SFTPB,C, PC, PG translocate from lamellar body to extracellular region (Homo sapiens)
ADRA2A,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Homo sapiens)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Homo sapiens)
ADRB2 in ADRB2:GRK complex is phosphorylated (Homo sapiens)
ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:Catecholamine binds ARRB1, ARRB2 (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
GRKs bind ADRB2:Catecholamine (Homo sapiens)
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
ADRB1:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
ADRB1:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
ADRB1:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
ADRB1:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
ADRB1:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Homo sapiens)
Liganded Gz-activating GPCR acts as a GEF for Gz (Homo sapiens)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gz complex dissociates (Homo sapiens)
ADR, NAd [extracellular region]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Adrenoceptors (Homo sapiens)
ADRA1A,B,D bind ADR,NAd (Homo sapiens)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Homo sapiens)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB1 bind ADR,NAd (Homo sapiens)
ADR, NAd [extracellular region]
ADRB1:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Homo sapiens)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3 bind ADR,NAd (Homo sapiens)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
ARBB recruits GPCRs into clathrin-coated pits (Homo sapiens)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ARRB bind GPCRs (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
ADR, NAd [extracellular region]
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
Platelet Aggregation (Plug Formation) (Mus musculus)
Adrenaline signalling through Alpha-2 adrenergic receptor (Mus musculus)
ADRA2A,B,C bind ADR,NAd (Mus musculus)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Metabolism (Mus musculus)
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Adrenaline,noradrenaline inhibits insulin secretion (Mus musculus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Mus musculus)
ADRA2A,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Mus musculus)
ADR, NAd [extracellular region]
ADRA2A,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Metabolism of proteins (Mus musculus)
Surfactant metabolism (Mus musculus)
SFTPB,C, PC, PG translocate from lamellar body to extracellular region (Mus musculus)
ADRA2A,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Mus musculus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Mus musculus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
The Ligand:GPCR:G12/13 complex dissociates (Mus musculus)
Ligands of GPCRs that activate G12/13 [extracellular region]
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
G alpha (q) signalling events (Mus musculus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
ADR, NAd [extracellular region]
G alpha (s) signalling events (Mus musculus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Mus musculus)
ADRB2:Catecholamine:GRK [plasma membrane] (Mus musculus)
ADRB2:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB2:Catecholamine binds ARRB1, ARRB2 (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
GRKs bind ADRB2:Catecholamine (Mus musculus)
ADRB2:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB2:Catecholamine:GRK [plasma membrane] (Mus musculus)
ADRB2:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
ADRB1:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
ADRB1:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
G alpha (z) signalling events (Mus musculus)
Liganded Gz-activating GPCR acts as a GEF for Gz (Mus musculus)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
The Ligand:GPCR:Gz complex dissociates (Mus musculus)
ADR, NAd [extracellular region]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Mus musculus)
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Amine ligand-binding receptors (Mus musculus)
Adrenoceptors (Mus musculus)
ADRA1A,B,D bind ADR,NAd (Mus musculus)
ADR, NAd [extracellular region]
ADRA1A,B,D:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRA2A,B,C bind ADR,NAd (Mus musculus)
ADR, NAd [extracellular region]
ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB1 bind ADR,NAd (Mus musculus)
ADR, NAd [extracellular region]
ADRB1:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB2 bind ADR,NAd (Mus musculus)
ADR, NAd [extracellular region]
ADRB2:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
ADRB3 bind ADR,NAd (Mus musculus)
ADR, NAd [extracellular region]
ADRB3:ADR,NAd [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Clathrin-mediated endocytosis (Mus musculus)
BAR domain proteins recruit dynamin (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Mus musculus)
ARRB-binding GPCRs [plasma membrane] (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Mus musculus)
ARRB-binding GPCRs [plasma membrane] (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Mus musculus)
ARRB-binding GPCRs [plasma membrane] (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Mus musculus)
ARRB-binding GPCRs [plasma membrane] (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]
Cargo recognition for clathrin-mediated endocytosis (Mus musculus)
ARBB recruits GPCRs into clathrin-coated pits (Mus musculus)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Mus musculus)
ARRB:ARRB-binding GPCRs [plasma membrane] (Mus musculus)
ARRB-binding GPCRs [plasma membrane] (Mus musculus)
pS-ADRB2:Catecholamine [plasma membrane] (Mus musculus)
ADR, NAd [extracellular region]