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DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Stable Identifier
R-ALL-449221
Type
Chemical Compound [SimpleEntity]
Compartment
integral component of cytoplasmic side of endoplasmic reticulum membrane
Synonyms
dolichol
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
Synthesis of Dolichyl-phosphate (Bos taurus)
DOLK phosphorylates DCHOL to DOLP (Bos taurus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Bos taurus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
Synthesis of substrates in N-glycan biosythesis (Caenorhabditis elegans)
Synthesis of Dolichyl-phosphate (Caenorhabditis elegans)
SRD5A3 reduces pPNOL to DCHOL (Caenorhabditis elegans)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
Synthesis of substrates in N-glycan biosythesis (Canis familiaris)
Synthesis of Dolichyl-phosphate (Canis familiaris)
DOLK phosphorylates DCHOL to DOLP (Canis familiaris)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Canis familiaris)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
Synthesis of substrates in N-glycan biosythesis (Danio rerio)
Synthesis of Dolichyl-phosphate (Danio rerio)
DOLK phosphorylates DCHOL to DOLP (Danio rerio)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Danio rerio)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
Synthesis of substrates in N-glycan biosythesis (Dictyostelium discoideum)
Synthesis of Dolichyl-phosphate (Dictyostelium discoideum)
DOLK phosphorylates DCHOL to DOLP (Dictyostelium discoideum)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Dictyostelium discoideum)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
Synthesis of substrates in N-glycan biosythesis (Drosophila melanogaster)
Synthesis of Dolichyl-phosphate (Drosophila melanogaster)
DOLK phosphorylates DCHOL to DOLP (Drosophila melanogaster)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Drosophila melanogaster)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
Synthesis of substrates in N-glycan biosythesis (Gallus gallus)
Synthesis of Dolichyl-phosphate (Gallus gallus)
DOLK phosphorylates DCHOL to DOLP (Gallus gallus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Gallus gallus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with glycosylation precursor biosynthesis (Homo sapiens)
Defective DOLK causes DOLK-CDG (Homo sapiens)
Defective DOLK does not phosphorylate DCHOL (Homo sapiens)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
Synthesis of Dolichyl-phosphate (Homo sapiens)
DOLK phosphorylates DCHOL to DOLP (Homo sapiens)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Homo sapiens)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
Synthesis of substrates in N-glycan biosythesis (Mus musculus)
Synthesis of Dolichyl-phosphate (Mus musculus)
DOLK phosphorylates DCHOL to DOLP (Mus musculus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Mus musculus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Asparagine N-linked glycosylation (Plasmodium falciparum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Plasmodium falciparum)
Synthesis of substrates in N-glycan biosythesis (Plasmodium falciparum)
Synthesis of Dolichyl-phosphate (Plasmodium falciparum)
SRD5A3 reduces pPNOL to DCHOL (Plasmodium falciparum)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
Synthesis of substrates in N-glycan biosythesis (Rattus norvegicus)
Synthesis of Dolichyl-phosphate (Rattus norvegicus)
DOLK phosphorylates DCHOL to DOLP (Rattus norvegicus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Rattus norvegicus)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Saccharomyces cerevisiae)
Synthesis of substrates in N-glycan biosythesis (Saccharomyces cerevisiae)
Synthesis of Dolichyl-phosphate (Saccharomyces cerevisiae)
DOLK phosphorylates DCHOL to DOLP (Saccharomyces cerevisiae)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Saccharomyces cerevisiae)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Asparagine N-linked glycosylation (Schizosaccharomyces pombe)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Schizosaccharomyces pombe)
Synthesis of substrates in N-glycan biosythesis (Schizosaccharomyces pombe)
Synthesis of Dolichyl-phosphate (Schizosaccharomyces pombe)
DOLK phosphorylates DCHOL to DOLP (Schizosaccharomyces pombe)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Schizosaccharomyces pombe)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
Synthesis of substrates in N-glycan biosythesis (Sus scrofa)
Synthesis of Dolichyl-phosphate (Sus scrofa)
DOLK phosphorylates DCHOL to DOLP (Sus scrofa)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Sus scrofa)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
Synthesis of substrates in N-glycan biosythesis (Xenopus tropicalis)
Synthesis of Dolichyl-phosphate (Xenopus tropicalis)
DOLK phosphorylates DCHOL to DOLP (Xenopus tropicalis)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
SRD5A3 reduces pPNOL to DCHOL (Xenopus tropicalis)
DCHOL [integral component of cytoplasmic side of endoplasmic reticulum membrane]
External Reference Information
External Reference
dolichol [ChEBI:16091]
Participates
as an input of
Defective DOLK does not phosphorylate DCHOL (Homo sapiens)
DOLK phosphorylates DCHOL to DOLP (Saccharomyces cerevisiae)
DOLK phosphorylates DCHOL to DOLP (Schizosaccharomyces pombe)
DOLK phosphorylates DCHOL to DOLP (Dictyostelium discoideum)
DOLK phosphorylates DCHOL to DOLP (Drosophila melanogaster)
DOLK phosphorylates DCHOL to DOLP (Gallus gallus)
DOLK phosphorylates DCHOL to DOLP (Xenopus tropicalis)
DOLK phosphorylates DCHOL to DOLP (Danio rerio)
DOLK phosphorylates DCHOL to DOLP (Sus scrofa)
DOLK phosphorylates DCHOL to DOLP (Bos taurus)
DOLK phosphorylates DCHOL to DOLP (Canis familiaris)
DOLK phosphorylates DCHOL to DOLP (Rattus norvegicus)
DOLK phosphorylates DCHOL to DOLP (Mus musculus)
DOLK phosphorylates DCHOL to DOLP (Homo sapiens)
as an output of
SRD5A3 reduces pPNOL to DCHOL (Plasmodium falciparum)
SRD5A3 reduces pPNOL to DCHOL (Saccharomyces cerevisiae)
SRD5A3 reduces pPNOL to DCHOL (Schizosaccharomyces pombe)
SRD5A3 reduces pPNOL to DCHOL (Dictyostelium discoideum)
SRD5A3 reduces pPNOL to DCHOL (Caenorhabditis elegans)
SRD5A3 reduces pPNOL to DCHOL (Drosophila melanogaster)
SRD5A3 reduces pPNOL to DCHOL (Gallus gallus)
SRD5A3 reduces pPNOL to DCHOL (Xenopus tropicalis)
SRD5A3 reduces pPNOL to DCHOL (Danio rerio)
SRD5A3 reduces pPNOL to DCHOL (Sus scrofa)
SRD5A3 reduces pPNOL to DCHOL (Bos taurus)
SRD5A3 reduces pPNOL to DCHOL (Canis familiaris)
SRD5A3 reduces pPNOL to DCHOL (Rattus norvegicus)
SRD5A3 reduces pPNOL to DCHOL (Mus musculus)
SRD5A3 reduces pPNOL to DCHOL (Homo sapiens)
Cross References
COMPOUND
C00381
HMDB Metabolite
HMDB0005176
ZINC
000030320745
,
000030320742
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