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(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Stable Identifier
R-ALL-449312
Type
Chemical Compound [SimpleEntity]
Compartment
integral component of lumenal side of endoplasmic reticulum membrane
Synonyms
alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-alpha-GlcNAc(PP-Dol)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Bos taurus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Bos taurus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Caenorhabditis elegans)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Caenorhabditis elegans)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Canis familiaris)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Canis familiaris)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Danio rerio)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Dictyostelium discoideum)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Dictyostelium discoideum)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Drosophila melanogaster)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Drosophila melanogaster)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Gallus gallus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Gallus gallus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with N-glycosylation of proteins (Homo sapiens)
Defective ALG12 causes CDG-1g (Homo sapiens)
Defective ALG12 does not add mannose to the N-glycan precursor (Homo sapiens)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Defective MPDU1 causes CDG-1f (Homo sapiens)
Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 (Homo sapiens)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Homo sapiens)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Homo sapiens)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Mus musculus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Mus musculus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Rattus norvegicus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Rattus norvegicus)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Saccharomyces cerevisiae)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Saccharomyces cerevisiae)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Saccharomyces cerevisiae)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Asparagine N-linked glycosylation (Schizosaccharomyces pombe)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Schizosaccharomyces pombe)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Schizosaccharomyces pombe)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Schizosaccharomyces pombe)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Sus scrofa)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Sus scrofa)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Xenopus tropicalis)
(GlcNAc)2 (Man)7 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
External Reference Information
External Reference
alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-alpha-GlcNAc(PP-Dol) [ChEBI:59088]
Participates
as an input of
Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 (Homo sapiens)
Defective ALG12 does not add mannose to the N-glycan precursor (Homo sapiens)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Saccharomyces cerevisiae)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Schizosaccharomyces pombe)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Dictyostelium discoideum)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Caenorhabditis elegans)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Drosophila melanogaster)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Gallus gallus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Danio rerio)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Sus scrofa)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Bos taurus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Canis familiaris)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Rattus norvegicus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Mus musculus)
ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Homo sapiens)
as an output of
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Saccharomyces cerevisiae)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Schizosaccharomyces pombe)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Dictyostelium discoideum)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Caenorhabditis elegans)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Drosophila melanogaster)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Gallus gallus)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Xenopus tropicalis)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Sus scrofa)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Bos taurus)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Canis familiaris)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Rattus norvegicus)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Mus musculus)
ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Homo sapiens)
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