Reactome | ATP,UTP [extracellular region]

ATP,UTP [extracellular region]

Stable Identifier

R-ALL-511955

Type

Set [DefinedSet]

Compartment

extracellular region

Locations in the PathwayBrowser

for Species:

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Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        P2RY2:ATP [plasma membrane] (Canis familiaris)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        P2RY2:ATP [plasma membrane] (Canis familiaris)
        
        ATP,UTP [extracellular region]
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        P2RY2:ATP [plasma membrane] (Canis familiaris)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        P2RY2:ATP [plasma membrane] (Canis familiaris)
        
        ATP,UTP [extracellular region]
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        P2RY2:ATP [plasma membrane] (Canis familiaris)
        
        ATP,UTP [extracellular region]
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Nucleotide-like (purinergic) receptors (Canis familiaris)
        
        P2Y receptors (Canis familiaris)
        
        P2Y2 receptor binds ATP and UTP (Canis familiaris)
        
        ATP,UTP [extracellular region]
        
        P2RY2:ATP [plasma membrane] (Canis familiaris)
        
        ATP,UTP [extracellular region]

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (q) signalling events (Danio rerio)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        P2RY2:ATP [plasma membrane] (Danio rerio)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        P2RY2:ATP [plasma membrane] (Danio rerio)
        
        ATP,UTP [extracellular region]
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        P2RY2:ATP [plasma membrane] (Danio rerio)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        P2RY2:ATP [plasma membrane] (Danio rerio)
        
        ATP,UTP [extracellular region]
      - The Ligand:GPCR:Gq complex dissociates (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        P2RY2:ATP [plasma membrane] (Danio rerio)
        
        ATP,UTP [extracellular region]
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Nucleotide-like (purinergic) receptors (Danio rerio)
        
        P2Y receptors (Danio rerio)
        
        P2Y2 receptor binds ATP and UTP (Danio rerio)
        
        ATP,UTP [extracellular region]
        
        P2RY2:ATP [plasma membrane] (Danio rerio)
        
        ATP,UTP [extracellular region]

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (q) signalling events (Homo sapiens)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
        
        P2RY2:ATP [plasma membrane] (Homo sapiens)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
        
        P2RY2:ATP [plasma membrane] (Homo sapiens)
        
        ATP,UTP [extracellular region]
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
        
        P2RY2:ATP [plasma membrane] (Homo sapiens)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
        
        P2RY2:ATP [plasma membrane] (Homo sapiens)
        
        ATP,UTP [extracellular region]
      - The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
        
        P2RY2:ATP [plasma membrane] (Homo sapiens)
        
        ATP,UTP [extracellular region]
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Nucleotide-like (purinergic) receptors (Homo sapiens)
        
        P2Y receptors (Homo sapiens)
        
        P2Y2 receptor binds ATP and UTP (Homo sapiens)
        
        ATP,UTP [extracellular region]
        
        P2RY2:ATP [plasma membrane] (Homo sapiens)
        
        ATP,UTP [extracellular region]

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        P2RY2:ATP [plasma membrane] (Mus musculus)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        P2RY2:ATP [plasma membrane] (Mus musculus)
        
        ATP,UTP [extracellular region]
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        P2RY2:ATP [plasma membrane] (Mus musculus)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        P2RY2:ATP [plasma membrane] (Mus musculus)
        
        ATP,UTP [extracellular region]
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        P2RY2:ATP [plasma membrane] (Mus musculus)
        
        ATP,UTP [extracellular region]
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Nucleotide-like (purinergic) receptors (Mus musculus)
        
        P2Y receptors (Mus musculus)
        
        P2Y2 receptor binds ATP and UTP (Mus musculus)
        
        ATP,UTP [extracellular region]
        
        P2RY2:ATP [plasma membrane] (Mus musculus)
        
        ATP,UTP [extracellular region]

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        P2RY2:ATP [plasma membrane] (Rattus norvegicus)
        
        ATP,UTP [extracellular region]
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        P2RY2:ATP [plasma membrane] (Rattus norvegicus)
        
        ATP,UTP [extracellular region]
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Nucleotide-like (purinergic) receptors (Rattus norvegicus)
        
        P2Y receptors (Rattus norvegicus)
        
        P2Y2 receptor binds ATP and UTP (Rattus norvegicus)
        
        ATP,UTP [extracellular region]
        
        P2RY2:ATP [plasma membrane] (Rattus norvegicus)
        
        ATP,UTP [extracellular region]

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