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Zn2+ [synaptic vesicle membrane]
Stable Identifier
R-ALL-5228942
Type
Chemical Compound [SimpleEntity]
Compartment
synaptic vesicle membrane
Synonyms
Zn++, zinc(2+), zinc, Zn(II)
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Neurotoxicity of clostridium toxins (Homo sapiens)
Toxicity of botulinum toxin type A (botA) (Homo sapiens)
botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botA HC:LC dimer:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
botA HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
botA LC:Zn2+ [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botA HC:LC dimer:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
botA HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
botA LC:Zn2+ [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
Toxicity of botulinum toxin type B (botB) (Homo sapiens)
botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botB HC:LC:SYT:GT1b [synaptic vesicle membrane] (Homo sapiens)
botB HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
botB LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botB:SYT:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botB HC:LC:SYT:GT1b [synaptic vesicle membrane] (Homo sapiens)
botB HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
botB LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
Toxicity of botulinum toxin type C (botC) (Homo sapiens)
botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol (Homo sapiens)
botC:GT1b [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/C HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/C LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botC:GT1b [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/C HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/C LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
Toxicity of botulinum toxin type D (botD) (Homo sapiens)
botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botD:SV2:GD2 [synaptic vesicle membrane] (Homo sapiens)
BoNT/D HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/D LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botD:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botD:SV2:GD2 [synaptic vesicle membrane] (Homo sapiens)
BoNT/D HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/D LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
Toxicity of botulinum toxin type E (botE) (Homo sapiens)
botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botE:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
BoNT/E HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/E LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botE:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
BoNT/E HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/E LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
Toxicity of botulinum toxin type F (botF) (Homo sapiens)
botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botF:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
BoNT/F HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/F LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botF:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
BoNT/F HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/F LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
Toxicity of botulinum toxin type G (botG) (Homo sapiens)
botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botG:SYT1:GT1b [synaptic vesicle membrane] (Homo sapiens)
BoNT/G HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/G LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
botG:SYT1:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botG:SYT1:GT1b [synaptic vesicle membrane] (Homo sapiens)
BoNT/G HC:LC dimer [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/G LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Zn2+ [synaptic vesicle membrane]
External Reference Information
External Reference
zinc(2+) [ChEBI:29105]
Participates
as a component of
botB LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/G LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/D LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/C LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
botA LC:Zn2+ [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/F LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
BoNT/E LC:Zn2+ disulfide bonded [synaptic vesicle membrane] (Clostridium botulinum)
Other forms of this molecule
Zn2+ [endocytic vesicle membrane]
Zn2+ [clathrin-coated endocytic vesicle membrane]
Zn2+ [endosome membrane]
Zn2+ [synaptic vesicle]
Zn2+ [secretory granule lumen]
Zn2+ [endosome lumen]
Zn2+ [endoplasmic reticulum lumen]
Zn2+ [Golgi membrane]
Zn2+ [phagocytic vesicle lumen]
Zn2+ [lysosomal lumen]
Zn2+ [Golgi lumen]
Zn2+ [mitochondrial intermembrane space]
Zn2+ [mitochondrial matrix]
Zn2+ [melanosome membrane]
Zn2+ [endoplasmic reticulum membrane]
Zn2+ [mitochondrial inner membrane]
Zn2+ [extracellular region]
Zn2+ [cytosol]
Zn2+ [plasma membrane]
Zn2+ [nucleoplasm]
Cross References
COMPOUND
C00038
PubChem Substance
11533263
HMDB Metabolite
HMDB0015532
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