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Ca2+ [cytosol]
Stable Identifier
R-ALL-74016
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Calcium, calcium(2+)
Icon
Locations in the PathwayBrowser for interactor UniProt:P80511 S100A12
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Extracellular matrix organization (Bos taurus)
Degradation of the extracellular matrix (Bos taurus)
CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Bos taurus)
Ca2+ [cytosol]
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
Effects of PIP2 hydrolysis (Bos taurus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Bos taurus)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Bos taurus)
Activation of conventional Protein Kinase C (Bos taurus)
Ca2+ [cytosol]
Platelet homeostasis (Bos taurus)
Platelet calcium homeostasis (Bos taurus)
Elevation of cytosolic Ca2+ levels (Bos taurus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Bos taurus)
Ca2+ [cytosol]
P2X1-mediated entry of Ca++ from plasma (Bos taurus)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Bos taurus)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Bos taurus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Bos taurus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)
Ca2+ [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Bos taurus)
STIM1 oligomerizes (Bos taurus)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Bos taurus)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of NF-kappaB in B cells (Bos taurus)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Bos taurus)
Ca2+ [cytosol]
Calcineurin activates NFAT (Bos taurus)
Calcineurin binds NFATC1,2,3 (Bos taurus)
Ca2+ [cytosol]
Innate Immune System (Bos taurus)
C-type lectin receptors (CLRs) (Bos taurus)
CLEC7A (Dectin-1) signaling (Bos taurus)
CLEC7A (Dectin-1) induces NFAT activation (Bos taurus)
Activation of Calcineurin (Bos taurus)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated Ca+2 mobilization (Bos taurus)
Activation of Calcineurin (Bos taurus)
Ca2+ [cytosol]
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Calcium Influx through Voltage-gated Calcium Channels (Bos taurus)
Ca2+ [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glycogen metabolism (Bos taurus)
Glycogen breakdown (glycogenolysis) (Bos taurus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Bos taurus)
Ca2+ [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Bos taurus)
Ca2+ [cytosol]
Metabolism of lipids (Bos taurus)
Phospholipid metabolism (Bos taurus)
Glycerophospholipid biosynthesis (Bos taurus)
CPNEs bind PL (Bos taurus)
Ca2+ [cytosol]
Muscle contraction (Bos taurus)
Cardiac conduction (Bos taurus)
Ion homeostasis (Bos taurus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Bos taurus)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Bos taurus)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Bos taurus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Bos taurus)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Bos taurus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Bos taurus)
Ca2+ [cytosol]
Phase 2 - plateau phase (Bos taurus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Bos taurus)
Ca2+ [cytosol]
Smooth Muscle Contraction (Bos taurus)
Calcium Binds Caldesmon (Bos taurus)
Ca2+ [cytosol]
Striated Muscle Contraction (Bos taurus)
Calcium Binds Troponin-C (Bos taurus)
Ca2+ [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
Acetylcholine binding and downstream events (Bos taurus)
Postsynaptic nicotinic acetylcholine receptors (Bos taurus)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Bos taurus)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Bos taurus)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Bos taurus)
Highly calcium permeable nicotinic acetylcholine receptors (Bos taurus)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Bos taurus)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Bos taurus)
Unblocking of NMDA receptors, glutamate binding and activation (Bos taurus)
Ca2+ influx into the post-synaptic cell (Bos taurus)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Bos taurus)
Ionotropic activity of kainate receptors (Bos taurus)
Activation of Ca-permeable Kainate Receptor (Bos taurus)
Activation of Ca-permeable Kainate receptors (Bos taurus)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Bos taurus)
Activation of AMPA receptors (Bos taurus)
Activation of Ca permeable AMPA receptors (Bos taurus)
Ca2+ [cytosol]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Bos taurus)
Ca2+ [cytosol]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Bos taurus)
Ca2+ [cytosol]
Neurotransmitter release cycle (Bos taurus)
GABA synthesis, release, reuptake and degradation (Bos taurus)
Release of GABA at the synapse (Bos taurus)
Ca2+ [cytosol]
Glutamate Neurotransmitter Release Cycle (Bos taurus)
Release of L-Glutamate at the synapse (Bos taurus)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Bos taurus)
Ca2+ influx through voltage gated Ca2+ channels (Bos taurus)
Ca2+ [cytosol]
Reproduction (Bos taurus)
Fertilization (Bos taurus)
Sperm Motility And Taxes (Bos taurus)
CatSper Channel Mediated Calcium Transport (Bos taurus)
Ca2+ [cytosol]
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Bos taurus)
Ca2+ [cytosol]
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Activation of the phototransduction cascade (Bos taurus)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Bos taurus)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
CALM1:Ca2+ binds CNG channel (Bos taurus)
Ca2+ [cytosol]
GRK1,4,7 phosphorylate MII to p-MII (Bos taurus)
Ca2+ [cytosol]
GUCA binds Ca2+ to form GUCA:Ca2+ (Bos taurus)
Ca2+ [cytosol]
PP2A dephosphorylates p-RHO to RHO (Bos taurus)
Ca2+ [cytosol]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Opioid Signalling (Bos taurus)
G-protein mediated events (Bos taurus)
PLC beta mediated events (Bos taurus)
Ca-dependent events (Bos taurus)
phospho-PLA2 pathway (Bos taurus)
Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Bos taurus)
Ca2+ [cytosol]
G alpha (q) signalling events (Bos taurus)
Effects of PIP2 hydrolysis (Bos taurus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Bos taurus)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated cell proliferation (Bos taurus)
DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)
Ca2+ [cytosol]
Signaling by WNT (Bos taurus)
Beta-catenin independent WNT signaling (Bos taurus)
Ca2+ pathway (Bos taurus)
Activation of Calcineurin (Bos taurus)
Ca2+ [cytosol]
Transport of small molecules (Bos taurus)
Glycosphingolipid transport (Bos taurus)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Bos taurus)
Ca2+ [cytosol]
Ion channel transport (Bos taurus)
Ion transport by P-type ATPases (Bos taurus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Bos taurus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Bos taurus)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Bos taurus)
Ca2+ [cytosol]
Stimuli-sensing channels (Bos taurus)
ANO1 transports cytosolic Cl- to extracellular region (Bos taurus)
Ca2+ [cytosol]
ANOs transport cytosolic Cl- to extracellular region (Bos taurus)
Ca2+ [cytosol]
BESTs transport cytosolic Cl- to extracellular region (Bos taurus)
Ca2+ [cytosol]
CLCAs self cleave (Bos taurus)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Bos taurus)
Ca2+ [cytosol]
TPCN1/2 transport lysosomal Ca2+ to cytosol (Bos taurus)
Ca2+ [cytosol]
TRP channels (Bos taurus)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Bos taurus)
Ca2+ [cytosol]
TRPV1 transports Ca2+ from extracellular region to cytosol (Bos taurus)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Bos taurus)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Bos taurus)
Ca2+ [cytosol]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Bos taurus)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Bos taurus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Sodium/Calcium exchangers (Bos taurus)
K+-independent Li+/Ca2+ exchanger transport (Bos taurus)
Ca2+ [cytosol]
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Bos taurus)
Ca2+ [cytosol]
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Bos taurus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)
Ca2+ [cytosol]
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Effects of PIP2 hydrolysis (Caenorhabditis elegans)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Caenorhabditis elegans)
Activation of conventional Protein Kinase C (Caenorhabditis elegans)
Ca2+ [cytosol]
Platelet homeostasis (Caenorhabditis elegans)
Platelet calcium homeostasis (Caenorhabditis elegans)
Elevation of cytosolic Ca2+ levels (Caenorhabditis elegans)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Caenorhabditis elegans)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Caenorhabditis elegans)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Caenorhabditis elegans)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)
Ca2+ [cytosol]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Signaling by the B Cell Receptor (BCR) (Caenorhabditis elegans)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Caenorhabditis elegans)
STIM1 oligomerizes (Caenorhabditis elegans)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Caenorhabditis elegans)
Activation of NF-kappaB in B cells (Caenorhabditis elegans)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Caenorhabditis elegans)
Ca2+ [cytosol]
Innate Immune System (Caenorhabditis elegans)
C-type lectin receptors (CLRs) (Caenorhabditis elegans)
CLEC7A (Dectin-1) signaling (Caenorhabditis elegans)
CLEC7A (Dectin-1) induces NFAT activation (Caenorhabditis elegans)
Activation of Calcineurin (Caenorhabditis elegans)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Caenorhabditis elegans)
FCERI mediated Ca+2 mobilization (Caenorhabditis elegans)
Activation of Calcineurin (Caenorhabditis elegans)
Ca2+ [cytosol]
Metabolism (Caenorhabditis elegans)
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Calcium Influx through Voltage-gated Calcium Channels (Caenorhabditis elegans)
Ca2+ [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glycogen metabolism (Caenorhabditis elegans)
Glycogen breakdown (glycogenolysis) (Caenorhabditis elegans)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Caenorhabditis elegans)
Ca2+ [cytosol]
Muscle contraction (Caenorhabditis elegans)
Cardiac conduction (Caenorhabditis elegans)
Ion homeostasis (Caenorhabditis elegans)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Caenorhabditis elegans)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Caenorhabditis elegans)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Phase 2 - plateau phase (Caenorhabditis elegans)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Smooth Muscle Contraction (Caenorhabditis elegans)
Calcium Binds Caldesmon (Caenorhabditis elegans)
Ca2+ [cytosol]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
Acetylcholine binding and downstream events (Caenorhabditis elegans)
Postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Highly calcium permeable nicotinic acetylcholine receptors (Caenorhabditis elegans)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Caenorhabditis elegans)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Caenorhabditis elegans)
Unblocking of NMDA receptors, glutamate binding and activation (Caenorhabditis elegans)
Ca2+ influx into the post-synaptic cell (Caenorhabditis elegans)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Caenorhabditis elegans)
Ionotropic activity of kainate receptors (Caenorhabditis elegans)
Activation of Ca-permeable Kainate Receptor (Caenorhabditis elegans)
Activation of Ca-permeable Kainate receptors (Caenorhabditis elegans)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Caenorhabditis elegans)
Activation of AMPA receptors (Caenorhabditis elegans)
Activation of Ca permeable AMPA receptors (Caenorhabditis elegans)
Ca2+ [cytosol]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Caenorhabditis elegans)
Ca2+ [cytosol]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Caenorhabditis elegans)
Ca2+ [cytosol]
Neurotransmitter release cycle (Caenorhabditis elegans)
GABA synthesis, release, reuptake and degradation (Caenorhabditis elegans)
Release of GABA at the synapse (Caenorhabditis elegans)
Ca2+ [cytosol]
Glutamate Neurotransmitter Release Cycle (Caenorhabditis elegans)
Release of L-Glutamate at the synapse (Caenorhabditis elegans)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Caenorhabditis elegans)
Ca2+ influx through voltage gated Ca2+ channels (Caenorhabditis elegans)
Ca2+ [cytosol]
Sensory Perception (Caenorhabditis elegans)
Sensory perception of taste (Caenorhabditis elegans)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Caenorhabditis elegans)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Visual phototransduction (Caenorhabditis elegans)
The phototransduction cascade (Caenorhabditis elegans)
Activation of the phototransduction cascade (Caenorhabditis elegans)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Caenorhabditis elegans)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Caenorhabditis elegans)
CALM1:Ca2+ binds CNG channel (Caenorhabditis elegans)
Ca2+ [cytosol]
GRK1,4,7 phosphorylate MII to p-MII (Caenorhabditis elegans)
Ca2+ [cytosol]
PP2A dephosphorylates p-RHO to RHO (Caenorhabditis elegans)
Ca2+ [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
Effects of PIP2 hydrolysis (Caenorhabditis elegans)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated cell proliferation (Caenorhabditis elegans)
DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)
Ca2+ [cytosol]
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
Ca2+ pathway (Caenorhabditis elegans)
Activation of Calcineurin (Caenorhabditis elegans)
Ca2+ [cytosol]
Transport of small molecules (Caenorhabditis elegans)
Glycosphingolipid transport (Caenorhabditis elegans)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Caenorhabditis elegans)
Ca2+ [cytosol]
Ion channel transport (Caenorhabditis elegans)
Ion transport by P-type ATPases (Caenorhabditis elegans)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Caenorhabditis elegans)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Caenorhabditis elegans)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Caenorhabditis elegans)
Ca2+ [cytosol]
Stimuli-sensing channels (Caenorhabditis elegans)
ANOs transport cytosolic Cl- to extracellular region (Caenorhabditis elegans)
Ca2+ [cytosol]
TRP channels (Caenorhabditis elegans)
TRPV1 transports Ca2+ from extracellular region to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Caenorhabditis elegans)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Caenorhabditis elegans)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Sodium/Calcium exchangers (Caenorhabditis elegans)
K+-independent Li+/Ca2+ exchanger transport (Caenorhabditis elegans)
Ca2+ [cytosol]
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Caenorhabditis elegans)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)
Ca2+ [cytosol]
Extracellular matrix organization (Canis familiaris)
Degradation of the extracellular matrix (Canis familiaris)
CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Canis familiaris)
Ca2+ [cytosol]
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Effects of PIP2 hydrolysis (Canis familiaris)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Canis familiaris)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Canis familiaris)
Activation of conventional Protein Kinase C (Canis familiaris)
Ca2+ [cytosol]
Platelet homeostasis (Canis familiaris)
Platelet calcium homeostasis (Canis familiaris)
Elevation of cytosolic Ca2+ levels (Canis familiaris)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Canis familiaris)
Ca2+ [cytosol]
P2X1-mediated entry of Ca++ from plasma (Canis familiaris)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Canis familiaris)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Canis familiaris)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Canis familiaris)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Canis familiaris)
Ca2+ [cytosol]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Canis familiaris)
STIM1 oligomerizes (Canis familiaris)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Canis familiaris)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of NF-kappaB in B cells (Canis familiaris)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Canis familiaris)
Ca2+ [cytosol]
Calcineurin activates NFAT (Canis familiaris)
Calcineurin binds NFATC1,2,3 (Canis familiaris)
Ca2+ [cytosol]
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CLEC7A (Dectin-1) signaling (Canis familiaris)
CLEC7A (Dectin-1) induces NFAT activation (Canis familiaris)
Activation of Calcineurin (Canis familiaris)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated Ca+2 mobilization (Canis familiaris)
Activation of Calcineurin (Canis familiaris)
Ca2+ [cytosol]
Metabolism (Canis familiaris)
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Calcium Influx through Voltage-gated Calcium Channels (Canis familiaris)
Ca2+ [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Glycogen metabolism (Canis familiaris)
Glycogen breakdown (glycogenolysis) (Canis familiaris)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Canis familiaris)
Ca2+ [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Canis familiaris)
Ca2+ [cytosol]
Metabolism of lipids (Canis familiaris)
Phospholipid metabolism (Canis familiaris)
Glycerophospholipid biosynthesis (Canis familiaris)
CPNEs bind PL (Canis familiaris)
Ca2+ [cytosol]
Muscle contraction (Canis familiaris)
Cardiac conduction (Canis familiaris)
Ion homeostasis (Canis familiaris)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Canis familiaris)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Canis familiaris)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Canis familiaris)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Canis familiaris)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Canis familiaris)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Canis familiaris)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Canis familiaris)
Ca2+ [cytosol]
Phase 2 - plateau phase (Canis familiaris)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Canis familiaris)
Ca2+ [cytosol]
Smooth Muscle Contraction (Canis familiaris)
Calcium Binds Caldesmon (Canis familiaris)
Ca2+ [cytosol]
Striated Muscle Contraction (Canis familiaris)
Calcium Binds Troponin-C (Canis familiaris)
Ca2+ [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
Acetylcholine binding and downstream events (Canis familiaris)
Postsynaptic nicotinic acetylcholine receptors (Canis familiaris)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Canis familiaris)
Highly calcium permeable nicotinic acetylcholine receptors (Canis familiaris)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Canis familiaris)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Canis familiaris)
Unblocking of NMDA receptors, glutamate binding and activation (Canis familiaris)
Ca2+ influx into the post-synaptic cell (Canis familiaris)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Canis familiaris)
Ionotropic activity of kainate receptors (Canis familiaris)
Activation of Ca-permeable Kainate Receptor (Canis familiaris)
Activation of Ca-permeable Kainate receptors (Canis familiaris)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Canis familiaris)
Activation of AMPA receptors (Canis familiaris)
Activation of Ca permeable AMPA receptors (Canis familiaris)
Ca2+ [cytosol]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Canis familiaris)
Ca2+ [cytosol]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Canis familiaris)
Ca2+ [cytosol]
Neurotransmitter release cycle (Canis familiaris)
GABA synthesis, release, reuptake and degradation (Canis familiaris)
Release of GABA at the synapse (Canis familiaris)
Ca2+ [cytosol]
Glutamate Neurotransmitter Release Cycle (Canis familiaris)
Release of L-Glutamate at the synapse (Canis familiaris)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Canis familiaris)
Ca2+ influx through voltage gated Ca2+ channels (Canis familiaris)
Ca2+ [cytosol]
Reproduction (Canis familiaris)
Fertilization (Canis familiaris)
Sperm Motility And Taxes (Canis familiaris)
CatSper Channel Mediated Calcium Transport (Canis familiaris)
Ca2+ [cytosol]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Canis familiaris)
Ca2+ [cytosol]
Visual phototransduction (Canis familiaris)
The phototransduction cascade (Canis familiaris)
Activation of the phototransduction cascade (Canis familiaris)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Canis familiaris)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Canis familiaris)
CALM1:Ca2+ binds CNG channel (Canis familiaris)
Ca2+ [cytosol]
GRK1,4,7 phosphorylate MII to p-MII (Canis familiaris)
Ca2+ [cytosol]
GUCA binds Ca2+ to form GUCA:Ca2+ (Canis familiaris)
Ca2+ [cytosol]
PP2A dephosphorylates p-RHO to RHO (Canis familiaris)
Ca2+ [cytosol]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Opioid Signalling (Canis familiaris)
G-protein mediated events (Canis familiaris)
PLC beta mediated events (Canis familiaris)
Ca-dependent events (Canis familiaris)
phospho-PLA2 pathway (Canis familiaris)
Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Canis familiaris)
Ca2+ [cytosol]
G alpha (q) signalling events (Canis familiaris)
Effects of PIP2 hydrolysis (Canis familiaris)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Canis familiaris)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFR2 mediated cell proliferation (Canis familiaris)
DAG and Ca+2 bind to PKC and tether it to membrane (Canis familiaris)
Ca2+ [cytosol]
Signaling by WNT (Canis familiaris)
Beta-catenin independent WNT signaling (Canis familiaris)
Ca2+ pathway (Canis familiaris)
Activation of Calcineurin (Canis familiaris)
Ca2+ [cytosol]
Transport of small molecules (Canis familiaris)
Glycosphingolipid transport (Canis familiaris)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Canis familiaris)
Ca2+ [cytosol]
Ion channel transport (Canis familiaris)
Ion transport by P-type ATPases (Canis familiaris)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Canis familiaris)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Canis familiaris)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Canis familiaris)
Ca2+ [cytosol]
Stimuli-sensing channels (Canis familiaris)
ANO1 transports cytosolic Cl- to extracellular region (Canis familiaris)
Ca2+ [cytosol]
ANOs transport cytosolic Cl- to extracellular region (Canis familiaris)
Ca2+ [cytosol]
BESTs transport cytosolic Cl- to extracellular region (Canis familiaris)
Ca2+ [cytosol]
CLCAs self cleave (Canis familiaris)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Canis familiaris)
Ca2+ [cytosol]
TPCN1/2 transport lysosomal Ca2+ to cytosol (Canis familiaris)
Ca2+ [cytosol]
TRP channels (Canis familiaris)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Canis familiaris)
Ca2+ [cytosol]
TRPV1 transports Ca2+ from extracellular region to cytosol (Canis familiaris)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Canis familiaris)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Canis familiaris)
Ca2+ [cytosol]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Canis familiaris)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Sodium/Calcium exchangers (Canis familiaris)
K+-independent Li+/Ca2+ exchanger transport (Canis familiaris)
Ca2+ [cytosol]
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Canis familiaris)
Ca2+ [cytosol]
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Canis familiaris)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Canis familiaris)
Ca2+ [cytosol]
Extracellular matrix organization (Danio rerio)
Degradation of the extracellular matrix (Danio rerio)
CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Danio rerio)
Ca2+ [cytosol]
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Response to elevated platelet cytosolic Ca2+ (Danio rerio)
Activation of conventional Protein Kinase C (Danio rerio)
Ca2+ [cytosol]
Platelet homeostasis (Danio rerio)
Platelet calcium homeostasis (Danio rerio)
Elevation of cytosolic Ca2+ levels (Danio rerio)
P2X1-mediated entry of Ca++ from plasma (Danio rerio)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Danio rerio)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Danio rerio)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Danio rerio)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Danio rerio)
Ca2+ [cytosol]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of NF-kappaB in B cells (Danio rerio)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Danio rerio)
Ca2+ [cytosol]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Phospholipid metabolism (Danio rerio)
Glycerophospholipid biosynthesis (Danio rerio)
CPNEs bind PL (Danio rerio)
Ca2+ [cytosol]
Muscle contraction (Danio rerio)
Cardiac conduction (Danio rerio)
Ion homeostasis (Danio rerio)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Danio rerio)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Danio rerio)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Danio rerio)
Ca2+ [cytosol]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter receptors and postsynaptic signal transmission (Danio rerio)
Acetylcholine binding and downstream events (Danio rerio)
Postsynaptic nicotinic acetylcholine receptors (Danio rerio)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Danio rerio)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Danio rerio)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Danio rerio)
Highly calcium permeable nicotinic acetylcholine receptors (Danio rerio)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Danio rerio)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Danio rerio)
Unblocking of NMDA receptors, glutamate binding and activation (Danio rerio)
Ca2+ influx into the post-synaptic cell (Danio rerio)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Danio rerio)
Activation of AMPA receptors (Danio rerio)
Activation of Ca permeable AMPA receptors (Danio rerio)
Ca2+ [cytosol]
Sensory Perception (Danio rerio)
Visual phototransduction (Danio rerio)
The phototransduction cascade (Danio rerio)
Inactivation, recovery and regulation of the phototransduction cascade (Danio rerio)
GRK1,4,7 phosphorylate MII to p-MII (Danio rerio)
Ca2+ [cytosol]
GUCA binds Ca2+ to form GUCA:Ca2+ (Danio rerio)
Ca2+ [cytosol]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Opioid Signalling (Danio rerio)
G-protein mediated events (Danio rerio)
PLC beta mediated events (Danio rerio)
Ca-dependent events (Danio rerio)
phospho-PLA2 pathway (Danio rerio)
Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Danio rerio)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
VEGFR2 mediated cell proliferation (Danio rerio)
DAG and Ca+2 bind to PKC and tether it to membrane (Danio rerio)
Ca2+ [cytosol]
Transport of small molecules (Danio rerio)
Ion channel transport (Danio rerio)
Ion transport by P-type ATPases (Danio rerio)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Danio rerio)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Danio rerio)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Danio rerio)
Ca2+ [cytosol]
Stimuli-sensing channels (Danio rerio)
ANOs transport cytosolic Cl- to extracellular region (Danio rerio)
Ca2+ [cytosol]
TPCN1/2 transport lysosomal Ca2+ to cytosol (Danio rerio)
Ca2+ [cytosol]
TRP channels (Danio rerio)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Danio rerio)
Ca2+ [cytosol]
TRPV1 transports Ca2+ from extracellular region to cytosol (Danio rerio)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Danio rerio)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Danio rerio)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Danio rerio)
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Sodium/Calcium exchangers (Danio rerio)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Danio rerio)
Ca2+ [cytosol]
Hemostasis (Dictyostelium discoideum)
Platelet activation, signaling and aggregation (Dictyostelium discoideum)
Effects of PIP2 hydrolysis (Dictyostelium discoideum)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Dictyostelium discoideum)
Activation of conventional Protein Kinase C (Dictyostelium discoideum)
Ca2+ [cytosol]
Platelet homeostasis (Dictyostelium discoideum)
Platelet calcium homeostasis (Dictyostelium discoideum)
Elevation of cytosolic Ca2+ levels (Dictyostelium discoideum)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
P2X1-mediated entry of Ca++ from plasma (Dictyostelium discoideum)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Dictyostelium discoideum)
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Dictyostelium discoideum)
Ca2+ [cytosol]
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Signaling by the B Cell Receptor (BCR) (Dictyostelium discoideum)
Downstream signaling events of B Cell Receptor (BCR) (Dictyostelium discoideum)
Activation of NF-kappaB in B cells (Dictyostelium discoideum)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Dictyostelium discoideum)
Ca2+ [cytosol]
Innate Immune System (Dictyostelium discoideum)
C-type lectin receptors (CLRs) (Dictyostelium discoideum)
CLEC7A (Dectin-1) signaling (Dictyostelium discoideum)
CLEC7A (Dectin-1) induces NFAT activation (Dictyostelium discoideum)
Activation of Calcineurin (Dictyostelium discoideum)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Dictyostelium discoideum)
FCERI mediated Ca+2 mobilization (Dictyostelium discoideum)
Activation of Calcineurin (Dictyostelium discoideum)
Ca2+ [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Phospholipid metabolism (Dictyostelium discoideum)
Glycerophospholipid biosynthesis (Dictyostelium discoideum)
CPNEs bind PL (Dictyostelium discoideum)
Ca2+ [cytosol]
Muscle contraction (Dictyostelium discoideum)
Cardiac conduction (Dictyostelium discoideum)
Ion homeostasis (Dictyostelium discoideum)
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Dictyostelium discoideum)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
Sensory Perception (Dictyostelium discoideum)
Sensory perception of taste (Dictyostelium discoideum)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Dictyostelium discoideum)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
Visual phototransduction (Dictyostelium discoideum)
The phototransduction cascade (Dictyostelium discoideum)
Inactivation, recovery and regulation of the phototransduction cascade (Dictyostelium discoideum)
GUCA binds Ca2+ to form GUCA:Ca2+ (Dictyostelium discoideum)
Ca2+ [cytosol]
Signal Transduction (Dictyostelium discoideum)
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (q) signalling events (Dictyostelium discoideum)
Effects of PIP2 hydrolysis (Dictyostelium discoideum)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated cell proliferation (Dictyostelium discoideum)
DAG and Ca+2 bind to PKC and tether it to membrane (Dictyostelium discoideum)
Ca2+ [cytosol]
Signaling by WNT (Dictyostelium discoideum)
Beta-catenin independent WNT signaling (Dictyostelium discoideum)
Ca2+ pathway (Dictyostelium discoideum)
Activation of Calcineurin (Dictyostelium discoideum)
Ca2+ [cytosol]
Transport of small molecules (Dictyostelium discoideum)
Ion channel transport (Dictyostelium discoideum)
Ion transport by P-type ATPases (Dictyostelium discoideum)
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Dictyostelium discoideum)
Ca2+ [cytosol]
Stimuli-sensing channels (Dictyostelium discoideum)
ANO1 transports cytosolic Cl- to extracellular region (Dictyostelium discoideum)
Ca2+ [cytosol]
ANOs transport cytosolic Cl- to extracellular region (Dictyostelium discoideum)
Ca2+ [cytosol]
TRP channels (Dictyostelium discoideum)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Dictyostelium discoideum)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Dictyostelium discoideum)
Ca2+ [cytosol]
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Effects of PIP2 hydrolysis (Drosophila melanogaster)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Activation of conventional Protein Kinase C (Drosophila melanogaster)
Ca2+ [cytosol]
Platelet homeostasis (Drosophila melanogaster)
Platelet calcium homeostasis (Drosophila melanogaster)
Elevation of cytosolic Ca2+ levels (Drosophila melanogaster)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Drosophila melanogaster)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Drosophila melanogaster)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Drosophila melanogaster)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
Ca2+ [cytosol]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Drosophila melanogaster)
STIM1 oligomerizes (Drosophila melanogaster)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Drosophila melanogaster)
Activation of NF-kappaB in B cells (Drosophila melanogaster)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Drosophila melanogaster)
Ca2+ [cytosol]
Calcineurin activates NFAT (Drosophila melanogaster)
Calcineurin binds NFATC1,2,3 (Drosophila melanogaster)
Ca2+ [cytosol]
Innate Immune System (Drosophila melanogaster)
C-type lectin receptors (CLRs) (Drosophila melanogaster)
CLEC7A (Dectin-1) signaling (Drosophila melanogaster)
CLEC7A (Dectin-1) induces NFAT activation (Drosophila melanogaster)
Activation of Calcineurin (Drosophila melanogaster)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated Ca+2 mobilization (Drosophila melanogaster)
Activation of Calcineurin (Drosophila melanogaster)
Ca2+ [cytosol]
Metabolism (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Calcium Influx through Voltage-gated Calcium Channels (Drosophila melanogaster)
Ca2+ [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Glycogen metabolism (Drosophila melanogaster)
Glycogen breakdown (glycogenolysis) (Drosophila melanogaster)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Drosophila melanogaster)
Ca2+ [cytosol]
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Ion homeostasis (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Drosophila melanogaster)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Drosophila melanogaster)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Phase 2 - plateau phase (Drosophila melanogaster)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Smooth Muscle Contraction (Drosophila melanogaster)
Calcium Binds Caldesmon (Drosophila melanogaster)
Ca2+ [cytosol]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Acetylcholine binding and downstream events (Drosophila melanogaster)
Postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Highly calcium permeable nicotinic acetylcholine receptors (Drosophila melanogaster)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Drosophila melanogaster)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Drosophila melanogaster)
Unblocking of NMDA receptors, glutamate binding and activation (Drosophila melanogaster)
Ca2+ influx into the post-synaptic cell (Drosophila melanogaster)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Drosophila melanogaster)
Ionotropic activity of kainate receptors (Drosophila melanogaster)
Activation of Ca-permeable Kainate Receptor (Drosophila melanogaster)
Activation of Ca-permeable Kainate receptors (Drosophila melanogaster)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Drosophila melanogaster)
Activation of AMPA receptors (Drosophila melanogaster)
Activation of Ca permeable AMPA receptors (Drosophila melanogaster)
Ca2+ [cytosol]
Neurotransmitter release cycle (Drosophila melanogaster)
GABA synthesis, release, reuptake and degradation (Drosophila melanogaster)
Release of GABA at the synapse (Drosophila melanogaster)
Ca2+ [cytosol]
Glutamate Neurotransmitter Release Cycle (Drosophila melanogaster)
Release of L-Glutamate at the synapse (Drosophila melanogaster)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Drosophila melanogaster)
Ca2+ influx through voltage gated Ca2+ channels (Drosophila melanogaster)
Ca2+ [cytosol]
Sensory Perception (Drosophila melanogaster)
Sensory perception of taste (Drosophila melanogaster)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Drosophila melanogaster)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Visual phototransduction (Drosophila melanogaster)
The phototransduction cascade (Drosophila melanogaster)
Activation of the phototransduction cascade (Drosophila melanogaster)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Drosophila melanogaster)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Drosophila melanogaster)
CALM1:Ca2+ binds CNG channel (Drosophila melanogaster)
Ca2+ [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
Effects of PIP2 hydrolysis (Drosophila melanogaster)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
DAG and Ca+2 bind to PKC and tether it to membrane (Drosophila melanogaster)
Ca2+ [cytosol]
Signaling by WNT (Drosophila melanogaster)
Beta-catenin independent WNT signaling (Drosophila melanogaster)
Ca2+ pathway (Drosophila melanogaster)
Activation of Calcineurin (Drosophila melanogaster)
Ca2+ [cytosol]
Transport of small molecules (Drosophila melanogaster)
Glycosphingolipid transport (Drosophila melanogaster)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Drosophila melanogaster)
Ca2+ [cytosol]
Ion channel transport (Drosophila melanogaster)
Ion transport by P-type ATPases (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Drosophila melanogaster)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Drosophila melanogaster)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Drosophila melanogaster)
Ca2+ [cytosol]
Stimuli-sensing channels (Drosophila melanogaster)
ANOs transport cytosolic Cl- to extracellular region (Drosophila melanogaster)
Ca2+ [cytosol]
BESTs transport cytosolic Cl- to extracellular region (Drosophila melanogaster)
Ca2+ [cytosol]
TRP channels (Drosophila melanogaster)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
TRPV1 transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Drosophila melanogaster)
Ca2+ [cytosol]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Drosophila melanogaster)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Sodium/Calcium exchangers (Drosophila melanogaster)
K+-independent Li+/Ca2+ exchanger transport (Drosophila melanogaster)
Ca2+ [cytosol]
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Drosophila melanogaster)
Ca2+ [cytosol]
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Drosophila melanogaster)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
Ca2+ [cytosol]
Hemostasis (Gallus gallus)
Platelet activation, signaling and aggregation (Gallus gallus)
Effects of PIP2 hydrolysis (Gallus gallus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Gallus gallus)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Gallus gallus)
Activation of conventional Protein Kinase C (Gallus gallus)
Ca2+ [cytosol]
Platelet homeostasis (Gallus gallus)
Platelet calcium homeostasis (Gallus gallus)
Elevation of cytosolic Ca2+ levels (Gallus gallus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Gallus gallus)
Ca2+ [cytosol]
P2X1-mediated entry of Ca++ from plasma (Gallus gallus)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Gallus gallus)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Gallus gallus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Gallus gallus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)
Ca2+ [cytosol]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Gallus gallus)
STIM1 oligomerizes (Gallus gallus)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Gallus gallus)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Gallus gallus)
Activation of NF-kappaB in B cells (Gallus gallus)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Gallus gallus)
Ca2+ [cytosol]
Calcineurin activates NFAT (Gallus gallus)
Calcineurin binds NFATC1,2,3 (Gallus gallus)
Ca2+ [cytosol]
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CLEC7A (Dectin-1) signaling (Gallus gallus)
CLEC7A (Dectin-1) induces NFAT activation (Gallus gallus)
Activation of Calcineurin (Gallus gallus)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated Ca+2 mobilization (Gallus gallus)
Activation of Calcineurin (Gallus gallus)
Ca2+ [cytosol]
Metabolism (Gallus gallus)
Integration of energy metabolism (Gallus gallus)
Regulation of insulin secretion (Gallus gallus)
Calcium Influx through Voltage-gated Calcium Channels (Gallus gallus)
Ca2+ [cytosol]
Metabolism of lipids (Gallus gallus)
Phospholipid metabolism (Gallus gallus)
Glycerophospholipid biosynthesis (Gallus gallus)
CPNEs bind PL (Gallus gallus)
Ca2+ [cytosol]
Muscle contraction (Gallus gallus)
Cardiac conduction (Gallus gallus)
Ion homeostasis (Gallus gallus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Gallus gallus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Gallus gallus)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Gallus gallus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Gallus gallus)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Gallus gallus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Gallus gallus)
Ca2+ [cytosol]
Phase 2 - plateau phase (Gallus gallus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Gallus gallus)
Ca2+ [cytosol]
Smooth Muscle Contraction (Gallus gallus)
Calcium Binds Caldesmon (Gallus gallus)
Ca2+ [cytosol]
Striated Muscle Contraction (Gallus gallus)
Calcium Binds Troponin-C (Gallus gallus)
Ca2+ [cytosol]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
Acetylcholine binding and downstream events (Gallus gallus)
Postsynaptic nicotinic acetylcholine receptors (Gallus gallus)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Gallus gallus)
Highly calcium permeable nicotinic acetylcholine receptors (Gallus gallus)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Gallus gallus)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Gallus gallus)
Unblocking of NMDA receptors, glutamate binding and activation (Gallus gallus)
Ca2+ influx into the post-synaptic cell (Gallus gallus)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Gallus gallus)
Ionotropic activity of kainate receptors (Gallus gallus)
Activation of Ca-permeable Kainate Receptor (Gallus gallus)
Activation of Ca-permeable Kainate receptors (Gallus gallus)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Gallus gallus)
Activation of AMPA receptors (Gallus gallus)
Activation of Ca permeable AMPA receptors (Gallus gallus)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Gallus gallus)
Ca2+ influx through voltage gated Ca2+ channels (Gallus gallus)
Ca2+ [cytosol]
Sensory Perception (Gallus gallus)
Visual phototransduction (Gallus gallus)
The phototransduction cascade (Gallus gallus)
Activation of the phototransduction cascade (Gallus gallus)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Gallus gallus)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Gallus gallus)
CALM1:Ca2+ binds CNG channel (Gallus gallus)
Ca2+ [cytosol]
GRK1,4,7 phosphorylate MII to p-MII (Gallus gallus)
Ca2+ [cytosol]
GUCA binds Ca2+ to form GUCA:Ca2+ (Gallus gallus)
Ca2+ [cytosol]
PP2A dephosphorylates p-RHO to RHO (Gallus gallus)
Ca2+ [cytosol]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Opioid Signalling (Gallus gallus)
G-protein mediated events (Gallus gallus)
PLC beta mediated events (Gallus gallus)
Ca-dependent events (Gallus gallus)
phospho-PLA2 pathway (Gallus gallus)
Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Gallus gallus)
Ca2+ [cytosol]
G alpha (q) signalling events (Gallus gallus)
Effects of PIP2 hydrolysis (Gallus gallus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Gallus gallus)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated cell proliferation (Gallus gallus)
DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)
Ca2+ [cytosol]
Signaling by WNT (Gallus gallus)
Beta-catenin independent WNT signaling (Gallus gallus)
Ca2+ pathway (Gallus gallus)
Activation of Calcineurin (Gallus gallus)
Ca2+ [cytosol]
Transport of small molecules (Gallus gallus)
Glycosphingolipid transport (Gallus gallus)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Gallus gallus)
Ca2+ [cytosol]
Ion channel transport (Gallus gallus)
Ion transport by P-type ATPases (Gallus gallus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Gallus gallus)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Gallus gallus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Gallus gallus)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)
Ca2+ [cytosol]
Stimuli-sensing channels (Gallus gallus)
ANO1 transports cytosolic Cl- to extracellular region (Gallus gallus)
Ca2+ [cytosol]
ANOs transport cytosolic Cl- to extracellular region (Gallus gallus)
Ca2+ [cytosol]
BESTs transport cytosolic Cl- to extracellular region (Gallus gallus)
Ca2+ [cytosol]
CLCAs self cleave (Gallus gallus)
Ca2+ [cytosol]
TPCN1/2 transport lysosomal Ca2+ to cytosol (Gallus gallus)
Ca2+ [cytosol]
TRP channels (Gallus gallus)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Gallus gallus)
Ca2+ [cytosol]
TRPV1 transports Ca2+ from extracellular region to cytosol (Gallus gallus)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Gallus gallus)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Gallus gallus)
Ca2+ [cytosol]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Gallus gallus)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Sodium/Calcium exchangers (Gallus gallus)
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Gallus gallus)
Ca2+ [cytosol]
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Gallus gallus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)
Ca2+ [cytosol]
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Defective Intrinsic Pathway for Apoptosis (Homo sapiens)
Neurodegenerative Diseases (Homo sapiens)
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models (Homo sapiens)
Calpain activation (Homo sapiens)
Ca2+ [cytosol]
Influx of extracellular calcium (Homo sapiens)
Ca2+ [cytosol]
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) (Homo sapiens)
Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Homo sapiens)
Ca2+ [cytosol]
Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) (Homo sapiens)
Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Homo sapiens)
Ca2+ [cytosol]
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
FCGR3A-mediated IL10 synthesis (Homo sapiens)
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 E transports Ca2+ (Homo sapiens)
Ca2+ [cytosol]
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
SARS-CoV-2 E pentamer transports Ca2+ (Homo sapiens)
Ca2+ [cytosol]
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Homo sapiens)
Ca2+ [cytosol]
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Effects of PIP2 hydrolysis (Homo sapiens)
Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs) (Homo sapiens)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Homo sapiens)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Activation of conventional Protein Kinase C (Homo sapiens)
Ca2+ [cytosol]
Platelet homeostasis (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Elevation of cytosolic Ca2+ levels (Homo sapiens)
CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Homo sapiens)
Ca2+ [cytosol]
P2X1-mediated entry of Ca++ from plasma (Homo sapiens)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Homo sapiens)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Homo sapiens)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Homo sapiens)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
Ca2+ [cytosol]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
STIM1 oligomerizes (Homo sapiens)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Homo sapiens)
Activation of NF-kappaB in B cells (Homo sapiens)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Homo sapiens)
Ca2+ [cytosol]
Calcineurin activates NFAT (Homo sapiens)
Calcineurin binds NFATC1,2,3 (Homo sapiens)
Ca2+ [cytosol]
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
CLEC7A (Dectin-1) induces NFAT activation (Homo sapiens)
Activation of Calcineurin (Homo sapiens)
Ca2+ [cytosol]
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated Ca+2 mobilization (Homo sapiens)
Activation of Calcineurin (Homo sapiens)
Ca2+ [cytosol]
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
FCERI mediated NF-kB activation (Homo sapiens)
RasGRP interacts with DAG and Ca2+ (Homo sapiens)
Ca2+ [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Role of phospholipids in phagocytosis (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Calcium Influx through Voltage-gated Calcium Channels (Homo sapiens)
Ca2+ [cytosol]
Exocytosis of Insulin (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Glycogen metabolism (Homo sapiens)
Glycogen breakdown (glycogenolysis) (Homo sapiens)
glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP (Homo sapiens)
Ca2+ [cytosol]
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Homo sapiens)
Ca2+ [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Homo sapiens)
Ca2+ [cytosol]
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
CPNEs bind PL (Homo sapiens)
Ca2+ [cytosol]
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
CALB1 binds 4xCa2+ (Homo sapiens)
Ca2+ [cytosol]
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Homo sapiens)
Ca2+ [cytosol]
CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Homo sapiens)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Homo sapiens)
Ca2+ [cytosol]
Phase 2 - plateau phase (Homo sapiens)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Homo sapiens)
Ca2+ [cytosol]
Smooth Muscle Contraction (Homo sapiens)
CAV3:TRIM72:DYSF binds ANXAs (Homo sapiens)
Ca2+ [cytosol]
Calcium Binds Caldesmon (Homo sapiens)
Ca2+ [cytosol]
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
DYSF, CAV3 and TRIM72 bind (Homo sapiens)
Ca2+ [cytosol]
Striated Muscle Contraction (Homo sapiens)
Calcium Binds Troponin-C (Homo sapiens)
Ca2+ [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Acetylcholine binding and downstream events (Homo sapiens)
Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
Long-term potentiation (Homo sapiens)
Calcium binds calmodulin at the synapse (Homo sapiens)
Ca2+ [cytosol]
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Ca2+ influx into the post-synaptic cell (Homo sapiens)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Homo sapiens)
Ionotropic activity of kainate receptors (Homo sapiens)
Activation of Ca-permeable Kainate Receptor (Homo sapiens)
Activation of Ca-permeable Kainate receptors (Homo sapiens)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
Activation of AMPA receptors (Homo sapiens)
Activation of Ca permeable AMPA receptors (Homo sapiens)
Ca2+ [cytosol]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Homo sapiens)
Ca2+ [cytosol]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Homo sapiens)
Ca2+ [cytosol]
Neurotransmitter release cycle (Homo sapiens)
GABA synthesis, release, reuptake and degradation (Homo sapiens)
Release of GABA at the synapse (Homo sapiens)
Ca2+ [cytosol]
Glutamate Neurotransmitter Release Cycle (Homo sapiens)
Release of L-Glutamate at the synapse (Homo sapiens)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Homo sapiens)
Ca2+ influx through voltage gated Ca2+ channels (Homo sapiens)
Ca2+ [cytosol]
Reproduction (Homo sapiens)
Fertilization (Homo sapiens)
Sperm Motility And Taxes (Homo sapiens)
CatSper Channel Mediated Calcium Transport (Homo sapiens)
Ca2+ [cytosol]
Sensory Perception (Homo sapiens)
Olfactory Signaling Pathway (Homo sapiens)
ANO2 dimer binds Ca2+ (Homo sapiens)
Ca2+ [cytosol]
cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Homo sapiens)
Ca2+ [cytosol]
TRPM4 transports Na+ from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
TRPM5 transports Na+ from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
Ca2+ [cytosol]
ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
Ca2+ [cytosol]
CACNA1D:CACNA2D2:CACNB2 (Cav1.3 channel) transports Ca2+ into the cytosol of an inner hair cell (Homo sapiens)
Ca2+ [cytosol]
Exocytosis of glutamate from cochlear inner hair cell (Homo sapiens)
Ca2+ [cytosol]
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
Ca2+ [cytosol]
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
Ca2+ [cytosol]
Acetylcholine inhibits contraction of outer hair cells (Homo sapiens)
CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol (Homo sapiens)
Ca2+ [cytosol]
KCNMA1:KCNMB1 transports potassium ions from the cytosol to the extracellular region (Homo sapiens)
Ca2+ [cytosol]
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
Ca2+ [cytosol]
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Activation of the phototransduction cascade (Homo sapiens)
SLC24A1 exchanges 4Na+ for Ca2+, K+ (Homo sapiens)
Ca2+ [cytosol]
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Homo sapiens)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
CALM1:Ca2+ binds CNG channel (Homo sapiens)
Ca2+ [cytosol]
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
GRK1,4,7 phosphorylate MII to p-MII (Homo sapiens)
Ca2+ [cytosol]
GUCA binds Ca2+ to form GUCA:Ca2+ (Homo sapiens)
Ca2+ [cytosol]
PP2A dephosphorylates p-RHO to RHO (Homo sapiens)
Ca2+ [cytosol]
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
phospho-PLA2 pathway (Homo sapiens)
Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
G alpha (q) signalling events (Homo sapiens)
Effects of PIP2 hydrolysis (Homo sapiens)
Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs) (Homo sapiens)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Homo sapiens)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated cell proliferation (Homo sapiens)
Calcium binds calmodulin (Homo sapiens)
Ca2+ [cytosol]
DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)
Ca2+ [cytosol]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
Activation of Calcineurin (Homo sapiens)
Ca2+ [cytosol]
Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT (Homo sapiens)
Ca2+ [cytosol]
Translocation and activation of PKC alpha in response to WNT signaling (Homo sapiens)
Ca2+ [cytosol]
Transport of small molecules (Homo sapiens)
Glycosphingolipid transport (Homo sapiens)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Homo sapiens)
Ca2+ [cytosol]
Ion channel transport (Homo sapiens)
Ion transport by P-type ATPases (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Homo sapiens)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Homo sapiens)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)
Ca2+ [cytosol]
Stimuli-sensing channels (Homo sapiens)
ANO1 transports cytosolic Cl- to extracellular region (Homo sapiens)
Ca2+ [cytosol]
ANOs transport cytosolic Cl- to extracellular region (Homo sapiens)
Ca2+ [cytosol]
BESTs transport cytosolic Cl- to extracellular region (Homo sapiens)
Ca2+ [cytosol]
CLCAs self cleave (Homo sapiens)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)
Ca2+ [cytosol]
TPCN1/2 transport lysosomal Ca2+ to cytosol (Homo sapiens)
Ca2+ [cytosol]
TRP channels (Homo sapiens)
TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Homo sapiens)
Ca2+ [cytosol]
TRPV1 transports Ca2+ from extracellular region to cytosol (Homo sapiens)
Ca2+ [cytosol]
TRPs transport extracellular Ca2+ to cytosol (Homo sapiens)
Ca2+ [cytosol]
TTYH2/3 transport cytosolic Cl- to extracellular region (Homo sapiens)
Ca2+ [cytosol]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Homo sapiens)
Ca2+ [cytosol]
Mitochondrial calcium ion transport (Homo sapiens)
SLC8A3 (NCX3) exchanges sodium (cytosol) for calcium (mitochondrial intermembrane space) (Homo sapiens)
Ca2+ [cytosol]
VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space (Homo sapiens)
Ca2+ [cytosol]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Sodium/Calcium exchangers (Homo sapiens)
K+-independent Li+/Ca2+ exchanger transport (Homo sapiens)
Ca2+ [cytosol]
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Homo sapiens)
Ca2+ [cytosol]
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
Ca2+ [cytosol]
Extracellular matrix organization (Mus musculus)
Degradation of the extracellular matrix (Mus musculus)
CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Mus musculus)
Ca2+ [cytosol]
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
Effects of PIP2 hydrolysis (Mus musculus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Mus musculus)
Ca2+ [cytosol]
Response to elevated platelet cytosolic Ca2+ (Mus musculus)
Activation of conventional Protein Kinase C (Mus musculus)
Ca2+ [cytosol]
Platelet homeostasis (Mus musculus)
Platelet calcium homeostasis (Mus musculus)
Elevation of cytosolic Ca2+ levels (Mus musculus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Mus musculus)
Ca2+ [cytosol]
P2X1-mediated entry of Ca++ from plasma (Mus musculus)
Ca2+ [cytosol]
Reduction of cytosolic Ca++ levels (Mus musculus)
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Mus musculus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Mus musculus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Mus musculus)
Ca2+ [cytosol]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Mus musculus)
STIM1 oligomerizes (Mus musculus)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Mus musculus)
Ca2+ [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of NF-kappaB in B cells (Mus musculus)
PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Mus musculus)
Ca2+ [cytosol]
Calcineurin activates NFAT (Mus musculus)
Calcineurin binds NFATC1,2,3 (Mus musculus)
Ca2+ [cytosol]
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
CLEC7A (Dectin-1) induces NFAT activation (Mus musculus)
Activation of Calcineurin (Mus musculus)
Ca2+ [cytosol]
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated Ca+2 mobilization (Mus musculus)
Activation of Calcineurin (Mus musculus)
Ca2+ [cytosol]
Metabolism (Mus musculus)
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Calcium Influx through Voltage-gated Calcium Channels (Mus musculus)
Ca2+ [cytosol]
Metabolism of carbohydrates (Mus musculus)
Glycogen metabolism (Mus musculus)
Glycogen breakdown (glycogenolysis) (Mus musculus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Mus musculus)
Ca2+ [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Mus musculus)
Ca2+ [cytosol]
Metabolism of lipids (Mus musculus)
Phospholipid metabolism (Mus musculus)
Glycerophospholipid biosynthesis (Mus musculus)
CPNEs bind PL (Mus musculus)
Ca2+ [cytosol]
Muscle contraction (Mus musculus)
Cardiac conduction (Mus musculus)
Ion homeostasis (Mus musculus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Mus musculus)
Ca2+ [cytosol]
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Mus musculus)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Mus musculus)
Ca2+ [cytosol]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Mus musculus)
Ca2+ [cytosol]
TRPC1 translocates calcium from the extracellular region to the cytosol (Mus musculus)
Ca2+ [cytosol]
Phase 0 - rapid depolarisation (Mus musculus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)
Ca2+ [cytosol]
Phase 2 - plateau phase (Mus musculus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)
Ca2+ [cytosol]
Smooth Muscle Contraction (Mus musculus)
Calcium Binds Caldesmon (Mus musculus)
Ca2+ [cytosol]
Striated Muscle Contraction (Mus musculus)
Calcium Binds Troponin-C (Mus musculus)
Ca2+ [cytosol]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter receptors and postsynaptic signal transmission (Mus musculus)
Acetylcholine binding and downstream events (Mus musculus)
Postsynaptic nicotinic acetylcholine receptors (Mus musculus)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Mus musculus)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Mus musculus)
Ca2+ [cytosol]
Presynaptic nicotinic acetylcholine receptors (Mus musculus)
Highly calcium permeable nicotinic acetylcholine receptors (Mus musculus)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Mus musculus)
Ca2+ [cytosol]
Activation of NMDA receptors and postsynaptic events (Mus musculus)
Unblocking of NMDA receptors, glutamate binding and activation (Mus musculus)
Ca2+ influx into the post-synaptic cell (Mus musculus)
Ca2+ [cytosol]
Activation of kainate receptors upon glutamate binding (Mus musculus)
Ionotropic activity of kainate receptors (Mus musculus)
Activation of Ca-permeable Kainate Receptor (Mus musculus)
Activation of Ca-permeable Kainate receptors (Mus musculus)
Ca2+ [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Mus musculus)
Activation of AMPA receptors (Mus musculus)
Activation of Ca permeable AMPA receptors (Mus musculus)
Ca2+ [cytosol]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Mus musculus)
Ca2+ [cytosol]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Mus musculus)
Ca2+ [cytosol]
Neurotransmitter release cycle (Mus musculus)
GABA synthesis, release, reuptake and degradation (Mus musculus)
Release of GABA at the synapse (Mus musculus)
Ca2+ [cytosol]
Glutamate Neurotransmitter Release Cycle (Mus musculus)
Release of L-Glutamate at the synapse (Mus musculus)
Ca2+ [cytosol]
Presynaptic depolarization and calcium channel opening (Mus musculus)
Ca2+ influx through voltage gated Ca2+ channels (Mus musculus)
Ca2+ [cytosol]
Reproduction (Mus musculus)
Fertilization (Mus musculus)
Sperm Motility And Taxes (Mus musculus)
CatSper Channel Mediated Calcium Transport (Mus musculus)
Ca2+ [cytosol]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Mus musculus)
Ca2+ [cytosol]
Visual phototransduction (Mus musculus)
The phototransduction cascade (Mus musculus)
Activation of the phototransduction cascade (Mus musculus)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Mus musculus)
Ca2+ [cytosol]
Inactivation, recovery and regulation of the phototransduction cascade (Mus musculus)
CALM1:Ca2+ binds CNG channel (Mus musculus)
Ca2+ [cytosol]
GRK1,4,7 phosphorylate MII to p-MII (Mus musculus)
Ca2+ [cytosol]
GUCA binds Ca2+ to form GUCA:Ca2+ (Mus musculus)
Ca2+ [cytosol]
PP2A dephosphorylates p-RHO to RHO (Mus musculus)
Ca2+ [cytosol]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Opioid Signalling (Mus musculus)
G-protein mediated events (Mus musculus)
PLC beta mediated events (Mus musculus)
Ca-dependent events (Mus musculus)
phospho-PLA2 pathway (Mus musculus)
Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Mus musculus)
Ca2+ [cytosol]
G alpha (q) signalling events (Mus musculus)
Effects of PIP2 hydrolysis (Mus musculus)
IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Mus musculus)
Ca2+ [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated cell proliferation (Mus musculus)
DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)
Ca2+ [cytosol]
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
Ca2+ pathway (Mus musculus)
Activation of Calcineurin (Mus musculus)
Ca2+ [cytosol]
Transport of small molecules (Mus musculus)
Glycosphingolipid transport (Mus musculus)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Mus musculus)
Ca2+ [cytosol]
Ion channel transport (Mus musculus)
Ion transport by P-type ATPases (Mus musculus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)
Ca2+ [cytosol]
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Mus musculus)
Ca2+ [cytosol]
ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Mus musculus)
Ca2+ [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)
Ca2+ [cytosol]
Stimuli-sensing channels (Mus musculus)
ANO1 transports cytosolic Cl- to extracellular region (Mus musculus)
Ca2+ [cytosol]
ANOs transport cytosolic Cl- to extracellular region (Mus musculus)
Ca2+ [cytosol]
BESTs transport cytosolic Cl- to extracellular region (Mus musculus)
Ca2+ [cytosol]
CLCAs self cleave (Mus musculus)
Ca2+ [cytosol]
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Mus musculus)
Ca2+ [cytosol]
![Ca2+ [cytosol] icon](/icon/R-ICO-012501.svg){kind=icon}