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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
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Analysis Tools
Analysis Data
Analysis Gene Expression
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Tissue Distribution
Diseases
Cytomics
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FAQ
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CoA-SH [cytosol]
Stable Identifier
R-ALL-76194
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
coenzyme A, coenzyme A(4-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Separation of Sister Chromatids (Bos taurus)
Deacetylation of cleaved cohesin (Bos taurus)
CoA-SH [cytosol]
Mitotic Prometaphase (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
Deacetylation of cohesin (Bos taurus)
CoA-SH [cytosol]
Drug ADME (Bos taurus)
Paracetamol ADME (Bos taurus)
NAT1,2 acetylate APAP-Cys to APAP-Mer (Bos taurus)
CoA-SH [cytosol]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Ethanol oxidation (Bos taurus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Bos taurus)
CoA-SH [cytosol]
Phase II - Conjugation of compounds (Bos taurus)
Acetylation (Bos taurus)
The acetyl group from acetyl-CoA is transferred to the NAT1 (Bos taurus)
CoA-SH [cytosol]
The acetyl group from acetyl-CoA is transferred to the NAT2 (Bos taurus)
CoA-SH [cytosol]
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Free fatty acids regulate insulin secretion (Bos taurus)
Intracellular metabolism of fatty acids regulates insulin secretion (Bos taurus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Bos taurus)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of amine-derived hormones (Bos taurus)
Serotonin and melatonin biosynthesis (Bos taurus)
N-acetylation of serotonin (Bos taurus)
CoA-SH [cytosol]
Metabolism of polyamines (Bos taurus)
Interconversion of polyamines (Bos taurus)
Spermidine => N-acetylated spermidine (Bos taurus)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Bos taurus)
CoA-SH [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glycosaminoglycan metabolism (Bos taurus)
Heparan sulfate/heparin (HS-GAG) metabolism (Bos taurus)
HS-GAG degradation (Bos taurus)
HGSNAT oligomer acetylates Heparan chain(1) (Bos taurus)
CoA-SH [cytosol]
HGSNAT oligomer acetylates Heparan sulfate chain(3) (Bos taurus)
CoA-SH [cytosol]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Carnitine shuttle (Bos taurus)
CPT1A transfers PALM to CAR (Bos taurus)
CoA-SH [cytosol]
CPT1B transfers PALM to CAR (Bos taurus)
CoA-SH [cytosol]
Fatty acyl-CoA biosynthesis (Bos taurus)
ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Bos taurus)
CoA-SH [cytosol]
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Bos taurus)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Bos taurus)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Bos taurus)
CoA-SH [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Bos taurus)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Bos taurus)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Bos taurus)
CoA-SH [cytosol]
ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Bos taurus)
CoA-SH [cytosol]
Mitochondrial Fatty Acid Beta-Oxidation (Bos taurus)
Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)
CoA-SH [cytosol]
Peroxisomal lipid metabolism (Bos taurus)
Beta-oxidation of very long chain fatty acids (Bos taurus)
Peroxisomal uptake of very long-chain fatty acyl CoA (Bos taurus)
CoA-SH [cytosol]
Ketone body metabolism (Bos taurus)
Synthesis of Ketone Bodies (Bos taurus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Bos taurus)
CoA-SH [cytosol]
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Recycling of bile acids and salts (Bos taurus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts (Bos taurus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Bos taurus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
CoA-SH [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
CoA-SH [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
CoA-SH [cytosol]
Cholesterol biosynthesis (Bos taurus)
ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Bos taurus)
CoA-SH [cytosol]
HMGCR dimer reduces bHMG-CoA to MVA (Bos taurus)
CoA-SH [cytosol]
HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Bos taurus)
CoA-SH [cytosol]
Phospholipid metabolism (Bos taurus)
Glycerophospholipid biosynthesis (Bos taurus)
Acyl chain remodeling of CL (Bos taurus)
DLCL is acylated to MLCL by LCLAT1 (ER) (Bos taurus)
CoA-SH [cytosol]
MLCL is acylated to CL by LCLAT1 (ER) (Bos taurus)
CoA-SH [cytosol]
Acyl chain remodeling of DAG and TAG (Bos taurus)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Bos taurus)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Bos taurus)
CoA-SH [cytosol]
DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Bos taurus)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Bos taurus)
1-acyl LPC is acylated to PC by LPCAT (Bos taurus)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Bos taurus)
CoA-SH [cytosol]
Acyl chain remodelling of PE (Bos taurus)
1-acyl LPE is acylated to PE by LPEAT (Bos taurus)
CoA-SH [cytosol]
2-acyl LPE is acylated to PE by LPEAT (Bos taurus)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Bos taurus)
1-acyl LPG is acylated to PG by LPGAT (Bos taurus)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Bos taurus)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Bos taurus)
1-acyl LPI is acylated to PI by MBOAT7 (Bos taurus)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Bos taurus)
CoA-SH [cytosol]
Acyl chain remodelling of PS (Bos taurus)
1-acyl LPS is acylated to PS by LPSAT (Bos taurus)
CoA-SH [cytosol]
2-acyl LPS is acylated to PS by LPSAT (Bos taurus)
CoA-SH [cytosol]
Synthesis of PA (Bos taurus)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Bos taurus)
CoA-SH [cytosol]
1-acyl LPA is acylated to PA by AGPAT5 (OM) (Bos taurus)
CoA-SH [cytosol]
DHAP is converted to 1-acyl GO3P by GNPAT (Bos taurus)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Bos taurus)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Bos taurus)
CoA-SH [cytosol]
Synthesis of PC (Bos taurus)
Cho is acetylated to AcCho by CHAT (Bos taurus)
CoA-SH [cytosol]
Sphingolipid metabolism (Bos taurus)
Sphingolipid de novo biosynthesis (Bos taurus)
Ceramide synthases transfer acyl-CoA onto sphingoid (Bos taurus)
CoA-SH [cytosol]
SPTLC complexes transfer acyl-CoA onto serine (Bos taurus)
CoA-SH [cytosol]
Triglyceride metabolism (Bos taurus)
Triglyceride biosynthesis (Bos taurus)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Bos taurus)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Bos taurus)
CoA-SH [cytosol]
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Bos taurus)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Bos taurus)
Wax biosynthesis (Bos taurus)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Bos taurus)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Bos taurus)
CoA-SH [cytosol]
FAR1 reduces PalmCoA to HXOL (Bos taurus)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Bos taurus)
CoA-SH [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Bos taurus)
eNOS activation (Bos taurus)
Palmitoylation of eNOS (Bos taurus)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Vitamin B5 (pantothenate) metabolism (Bos taurus)
Coenzyme A biosynthesis (Bos taurus)
COASY phosphorylates DP-CoA (Bos taurus)
CoA-SH [cytosol]
DCAKD phosphorylates DP-CoA (Bos taurus)
CoA-SH [cytosol]
PANK2 phosphorylates PanK (Bos taurus)
CoA-SH [cytosol]
Phosphopantetheine conjugation of the ACP domain of FAS (Bos taurus)
CoA-SH [cytosol]
SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Bos taurus)
CoA-SH [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Bos taurus)
CoA-SH [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
Synthesis of UDP-N-acetyl-glucosamine (Bos taurus)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Bos taurus)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Bos taurus)
Synthesis of glycosylphosphatidylinositol (GPI) (Bos taurus)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Bos taurus)
CoA-SH [cytosol]
Surfactant metabolism (Bos taurus)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Bos taurus)
CoA-SH [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter release cycle (Bos taurus)
Acetylcholine Neurotransmitter Release Cycle (Bos taurus)
Cho is acetylated to AcCho by CHAT (Bos taurus)
CoA-SH [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
ATAT acetylates microtubules (Bos taurus)
CoA-SH [cytosol]
HDAC6 deacetylates microtubules (Bos taurus)
CoA-SH [cytosol]
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
NMT1/2 transfer MYS to GNAT1 (Bos taurus)
CoA-SH [cytosol]
The retinoid cycle in cones (daylight vision) (Bos taurus)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Bos taurus)
CoA-SH [cytosol]
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS processing (Bos taurus)
S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Bos taurus)
CoA-SH [cytosol]
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
ZDHHC7, ZDHHC21 palmitoylate ESR1 (Bos taurus)
CoA-SH [cytosol]
Transport of small molecules (Bos taurus)
Plasma lipoprotein assembly, remodeling, and clearance (Bos taurus)
Plasma lipoprotein assembly (Bos taurus)
HDL assembly (Bos taurus)
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Bos taurus)
CoA-SH [cytosol]
Plasma lipoprotein clearance (Bos taurus)
LDL clearance (Bos taurus)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Bos taurus)
CoA-SH [cytosol]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Bos taurus)
CoA-SH [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Ethanol oxidation (Caenorhabditis elegans)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Caenorhabditis elegans)
CoA-SH [cytosol]
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Free fatty acids regulate insulin secretion (Caenorhabditis elegans)
Intracellular metabolism of fatty acids regulates insulin secretion (Caenorhabditis elegans)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Caenorhabditis elegans)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of polyamines (Caenorhabditis elegans)
Interconversion of polyamines (Caenorhabditis elegans)
Spermidine => N-acetylated spermidine (Caenorhabditis elegans)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Caenorhabditis elegans)
CoA-SH [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Carnitine shuttle (Caenorhabditis elegans)
CPT1A transfers PALM to CAR (Caenorhabditis elegans)
CoA-SH [cytosol]
CPT1B transfers PALM to CAR (Caenorhabditis elegans)
CoA-SH [cytosol]
Fatty acyl-CoA biosynthesis (Caenorhabditis elegans)
ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Caenorhabditis elegans)
CoA-SH [cytosol]
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Caenorhabditis elegans)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Mitochondrial Fatty Acid Beta-Oxidation (Caenorhabditis elegans)
Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Peroxisomal lipid metabolism (Caenorhabditis elegans)
Beta-oxidation of very long chain fatty acids (Caenorhabditis elegans)
Peroxisomal uptake of very long-chain fatty acyl CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Ketone body metabolism (Caenorhabditis elegans)
Synthesis of Ketone Bodies (Caenorhabditis elegans)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Metabolism of steroids (Caenorhabditis elegans)
Bile acid and bile salt metabolism (Caenorhabditis elegans)
Recycling of bile acids and salts (Caenorhabditis elegans)
Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Caenorhabditis elegans)
CoA-SH [cytosol]
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts (Caenorhabditis elegans)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Caenorhabditis elegans)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
CoA-SH [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Caenorhabditis elegans)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
CoA-SH [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
CoA-SH [cytosol]
Cholesterol biosynthesis (Caenorhabditis elegans)
HMGCR dimer reduces bHMG-CoA to MVA (Caenorhabditis elegans)
CoA-SH [cytosol]
HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Phospholipid metabolism (Caenorhabditis elegans)
Glycerophospholipid biosynthesis (Caenorhabditis elegans)
Acyl chain remodeling of CL (Caenorhabditis elegans)
DLCL is acylated to MLCL by LCLAT1 (ER) (Caenorhabditis elegans)
CoA-SH [cytosol]
MLCL is acylated to CL by LCLAT1 (ER) (Caenorhabditis elegans)
CoA-SH [cytosol]
Acyl chain remodeling of DAG and TAG (Caenorhabditis elegans)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Caenorhabditis elegans)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Caenorhabditis elegans)
CoA-SH [cytosol]
DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Caenorhabditis elegans)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Caenorhabditis elegans)
1-acyl LPC is acylated to PC by LPCAT (Caenorhabditis elegans)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Caenorhabditis elegans)
CoA-SH [cytosol]
Acyl chain remodelling of PE (Caenorhabditis elegans)
1-acyl LPE is acylated to PE by LPEAT (Caenorhabditis elegans)
CoA-SH [cytosol]
2-acyl LPE is acylated to PE by LPEAT (Caenorhabditis elegans)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Caenorhabditis elegans)
1-acyl LPG is acylated to PG by LPGAT (Caenorhabditis elegans)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Caenorhabditis elegans)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Caenorhabditis elegans)
1-acyl LPI is acylated to PI by MBOAT7 (Caenorhabditis elegans)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Caenorhabditis elegans)
CoA-SH [cytosol]
Acyl chain remodelling of PS (Caenorhabditis elegans)
1-acyl LPS is acylated to PS by LPSAT (Caenorhabditis elegans)
CoA-SH [cytosol]
2-acyl LPS is acylated to PS by LPSAT (Caenorhabditis elegans)
CoA-SH [cytosol]
Synthesis of PA (Caenorhabditis elegans)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Caenorhabditis elegans)
CoA-SH [cytosol]
1-acyl LPA is acylated to PA by AGPAT5 (OM) (Caenorhabditis elegans)
CoA-SH [cytosol]
DHAP is converted to 1-acyl GO3P by GNPAT (Caenorhabditis elegans)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Caenorhabditis elegans)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Caenorhabditis elegans)
CoA-SH [cytosol]
Synthesis of PC (Caenorhabditis elegans)
Cho is acetylated to AcCho by CHAT (Caenorhabditis elegans)
CoA-SH [cytosol]
Sphingolipid metabolism (Caenorhabditis elegans)
Sphingolipid de novo biosynthesis (Caenorhabditis elegans)
Ceramide synthases transfer acyl-CoA onto sphingoid (Caenorhabditis elegans)
CoA-SH [cytosol]
Triglyceride metabolism (Caenorhabditis elegans)
Triglyceride biosynthesis (Caenorhabditis elegans)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Caenorhabditis elegans)
CoA-SH [cytosol]
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Caenorhabditis elegans)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Caenorhabditis elegans)
CoA-SH [cytosol]
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Caenorhabditis elegans)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Caenorhabditis elegans)
Wax biosynthesis (Caenorhabditis elegans)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Caenorhabditis elegans)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Caenorhabditis elegans)
CoA-SH [cytosol]
FAR1 reduces PalmCoA to HXOL (Caenorhabditis elegans)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Caenorhabditis elegans)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Vitamin B5 (pantothenate) metabolism (Caenorhabditis elegans)
Coenzyme A biosynthesis (Caenorhabditis elegans)
COASY phosphorylates DP-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
DCAKD phosphorylates DP-CoA (Caenorhabditis elegans)
CoA-SH [cytosol]
Phosphopantetheine conjugation of the ACP domain of FAS (Caenorhabditis elegans)
CoA-SH [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Caenorhabditis elegans)
CoA-SH [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
Synthesis of substrates in N-glycan biosythesis (Caenorhabditis elegans)
Synthesis of UDP-N-acetyl-glucosamine (Caenorhabditis elegans)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Caenorhabditis elegans)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Caenorhabditis elegans)
Synthesis of glycosylphosphatidylinositol (GPI) (Caenorhabditis elegans)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Caenorhabditis elegans)
CoA-SH [cytosol]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter release cycle (Caenorhabditis elegans)
Acetylcholine Neurotransmitter Release Cycle (Caenorhabditis elegans)
Cho is acetylated to AcCho by CHAT (Caenorhabditis elegans)
CoA-SH [cytosol]
Signal Transduction (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
RAS processing (Caenorhabditis elegans)
S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Caenorhabditis elegans)
CoA-SH [cytosol]
Transport of small molecules (Caenorhabditis elegans)
Plasma lipoprotein assembly, remodeling, and clearance (Caenorhabditis elegans)
Plasma lipoprotein clearance (Caenorhabditis elegans)
LDL clearance (Caenorhabditis elegans)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Caenorhabditis elegans)
CoA-SH [cytosol]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Separation of Sister Chromatids (Canis familiaris)
Deacetylation of cleaved cohesin (Canis familiaris)
CoA-SH [cytosol]
Mitotic Prometaphase (Canis familiaris)
Resolution of Sister Chromatid Cohesion (Canis familiaris)
Deacetylation of cohesin (Canis familiaris)
CoA-SH [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Ethanol oxidation (Canis familiaris)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Canis familiaris)
CoA-SH [cytosol]
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Free fatty acids regulate insulin secretion (Canis familiaris)
Intracellular metabolism of fatty acids regulates insulin secretion (Canis familiaris)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of amine-derived hormones (Canis familiaris)
Serotonin and melatonin biosynthesis (Canis familiaris)
N-acetylation of serotonin (Canis familiaris)
CoA-SH [cytosol]
Metabolism of polyamines (Canis familiaris)
Interconversion of polyamines (Canis familiaris)
Spermidine => N-acetylated spermidine (Canis familiaris)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Canis familiaris)
CoA-SH [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Glycosaminoglycan metabolism (Canis familiaris)
Heparan sulfate/heparin (HS-GAG) metabolism (Canis familiaris)
HS-GAG degradation (Canis familiaris)
HGSNAT oligomer acetylates Heparan chain(1) (Canis familiaris)
CoA-SH [cytosol]
HGSNAT oligomer acetylates Heparan sulfate chain(3) (Canis familiaris)
CoA-SH [cytosol]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Carnitine shuttle (Canis familiaris)
CPT1A transfers PALM to CAR (Canis familiaris)
CoA-SH [cytosol]
CPT1B transfers PALM to CAR (Canis familiaris)
CoA-SH [cytosol]
Fatty acyl-CoA biosynthesis (Canis familiaris)
ACLY tetramer transforms CIT to Ac-CoA (Canis familiaris)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Canis familiaris)
CoA-SH [cytosol]
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Canis familiaris)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Canis familiaris)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Canis familiaris)
CoA-SH [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Canis familiaris)
CoA-SH [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Canis familiaris)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Canis familiaris)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Canis familiaris)
CoA-SH [cytosol]
ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Canis familiaris)
CoA-SH [cytosol]
Mitochondrial Fatty Acid Beta-Oxidation (Canis familiaris)
Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Canis familiaris)
CoA-SH [cytosol]
Peroxisomal lipid metabolism (Canis familiaris)
Beta-oxidation of very long chain fatty acids (Canis familiaris)
Peroxisomal uptake of very long-chain fatty acyl CoA (Canis familiaris)
CoA-SH [cytosol]
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Recycling of bile acids and salts (Canis familiaris)
Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Canis familiaris)
CoA-SH [cytosol]
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Canis familiaris)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
CoA-SH [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
CoA-SH [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
CoA-SH [cytosol]
Cholesterol biosynthesis (Canis familiaris)
ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Canis familiaris)
CoA-SH [cytosol]
HMGCR dimer reduces bHMG-CoA to MVA (Canis familiaris)
CoA-SH [cytosol]
HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Canis familiaris)
CoA-SH [cytosol]
Phospholipid metabolism (Canis familiaris)
Glycerophospholipid biosynthesis (Canis familiaris)
Acyl chain remodeling of CL (Canis familiaris)
DLCL is acylated to MLCL by LCLAT1 (ER) (Canis familiaris)
CoA-SH [cytosol]
MLCL is acylated to CL by LCLAT1 (ER) (Canis familiaris)
CoA-SH [cytosol]
Acyl chain remodeling of DAG and TAG (Canis familiaris)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Canis familiaris)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Canis familiaris)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Canis familiaris)
1-acyl LPC is acylated to PC by LPCAT (Canis familiaris)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Canis familiaris)
CoA-SH [cytosol]
Acyl chain remodelling of PE (Canis familiaris)
1-acyl LPE is acylated to PE by LPEAT (Canis familiaris)
CoA-SH [cytosol]
2-acyl LPE is acylated to PE by LPEAT (Canis familiaris)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Canis familiaris)
1-acyl LPG is acylated to PG by LPGAT (Canis familiaris)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Canis familiaris)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Canis familiaris)
1-acyl LPI is acylated to PI by MBOAT7 (Canis familiaris)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Canis familiaris)
CoA-SH [cytosol]
Acyl chain remodelling of PS (Canis familiaris)
1-acyl LPS is acylated to PS by LPSAT (Canis familiaris)
CoA-SH [cytosol]
2-acyl LPS is acylated to PS by LPSAT (Canis familiaris)
CoA-SH [cytosol]
Synthesis of PA (Canis familiaris)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Canis familiaris)
CoA-SH [cytosol]
1-acyl LPA is acylated to PA by AGPAT5 (OM) (Canis familiaris)
CoA-SH [cytosol]
DHAP is converted to 1-acyl GO3P by GNPAT (Canis familiaris)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Canis familiaris)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Canis familiaris)
CoA-SH [cytosol]
Synthesis of PC (Canis familiaris)
Cho is acetylated to AcCho by CHAT (Canis familiaris)
CoA-SH [cytosol]
Sphingolipid metabolism (Canis familiaris)
Sphingolipid de novo biosynthesis (Canis familiaris)
Ceramide synthases transfer acyl-CoA onto sphingoid (Canis familiaris)
CoA-SH [cytosol]
SPTLC complexes transfer acyl-CoA onto serine (Canis familiaris)
CoA-SH [cytosol]
Triglyceride metabolism (Canis familiaris)
Triglyceride biosynthesis (Canis familiaris)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Canis familiaris)
CoA-SH [cytosol]
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Canis familiaris)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Canis familiaris)
CoA-SH [cytosol]
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Canis familiaris)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Canis familiaris)
Wax biosynthesis (Canis familiaris)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Canis familiaris)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Canis familiaris)
CoA-SH [cytosol]
FAR1 reduces PalmCoA to HXOL (Canis familiaris)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Canis familiaris)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Vitamin B5 (pantothenate) metabolism (Canis familiaris)
Coenzyme A biosynthesis (Canis familiaris)
COASY phosphorylates DP-CoA (Canis familiaris)
CoA-SH [cytosol]
DCAKD phosphorylates DP-CoA (Canis familiaris)
CoA-SH [cytosol]
PANK2 phosphorylates PanK (Canis familiaris)
CoA-SH [cytosol]
Phosphopantetheine conjugation of the ACP domain of FAS (Canis familiaris)
CoA-SH [cytosol]
SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Canis familiaris)
CoA-SH [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Canis familiaris)
CoA-SH [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
Synthesis of substrates in N-glycan biosythesis (Canis familiaris)
Synthesis of UDP-N-acetyl-glucosamine (Canis familiaris)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Canis familiaris)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Canis familiaris)
Synthesis of glycosylphosphatidylinositol (GPI) (Canis familiaris)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Canis familiaris)
CoA-SH [cytosol]
Surfactant metabolism (Canis familiaris)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Canis familiaris)
CoA-SH [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter release cycle (Canis familiaris)
Acetylcholine Neurotransmitter Release Cycle (Canis familiaris)
Cho is acetylated to AcCho by CHAT (Canis familiaris)
CoA-SH [cytosol]
Organelle biogenesis and maintenance (Canis familiaris)
Cilium Assembly (Canis familiaris)
ATAT acetylates microtubules (Canis familiaris)
CoA-SH [cytosol]
HDAC6 deacetylates microtubules (Canis familiaris)
CoA-SH [cytosol]
Sensory Perception (Canis familiaris)
Visual phototransduction (Canis familiaris)
The phototransduction cascade (Canis familiaris)
Inactivation, recovery and regulation of the phototransduction cascade (Canis familiaris)
NMT1/2 transfer MYS to GNAT1 (Canis familiaris)
CoA-SH [cytosol]
The retinoid cycle in cones (daylight vision) (Canis familiaris)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Canis familiaris)
CoA-SH [cytosol]
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS processing (Canis familiaris)
S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Canis familiaris)
CoA-SH [cytosol]
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Extra-nuclear estrogen signaling (Canis familiaris)
ZDHHC7, ZDHHC21 palmitoylate ESR1 (Canis familiaris)
CoA-SH [cytosol]
Transport of small molecules (Canis familiaris)
Plasma lipoprotein assembly, remodeling, and clearance (Canis familiaris)
Plasma lipoprotein assembly (Canis familiaris)
HDL assembly (Canis familiaris)
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Canis familiaris)
CoA-SH [cytosol]
Plasma lipoprotein clearance (Canis familiaris)
LDL clearance (Canis familiaris)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Canis familiaris)
CoA-SH [cytosol]
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
Golgi-to-ER retrograde transport (Canis familiaris)
COPI-independent Golgi-to-ER retrograde traffic (Canis familiaris)
LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Canis familiaris)
CoA-SH [cytosol]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Prometaphase (Danio rerio)
Resolution of Sister Chromatid Cohesion (Danio rerio)
Deacetylation of cohesin (Danio rerio)
CoA-SH [cytosol]
Drug ADME (Danio rerio)
Paracetamol ADME (Danio rerio)
NAT1,2 acetylate APAP-Cys to APAP-Mer (Danio rerio)
CoA-SH [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Acetylation (Danio rerio)
The acetyl group from acetyl-CoA is transferred to the NAT1 (Danio rerio)
CoA-SH [cytosol]
The acetyl group from acetyl-CoA is transferred to the NAT2 (Danio rerio)
CoA-SH [cytosol]
Integration of energy metabolism (Danio rerio)
Regulation of insulin secretion (Danio rerio)
Free fatty acids regulate insulin secretion (Danio rerio)
Intracellular metabolism of fatty acids regulates insulin secretion (Danio rerio)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Danio rerio)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of amine-derived hormones (Danio rerio)
Serotonin and melatonin biosynthesis (Danio rerio)
N-acetylation of serotonin (Danio rerio)
CoA-SH [cytosol]
Metabolism of polyamines (Danio rerio)
Interconversion of polyamines (Danio rerio)
Spermidine => N-acetylated spermidine (Danio rerio)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Danio rerio)
CoA-SH [cytosol]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Carnitine shuttle (Danio rerio)
CPT1B transfers PALM to CAR (Danio rerio)
CoA-SH [cytosol]
Fatty acyl-CoA biosynthesis (Danio rerio)
ACLY tetramer transforms CIT to Ac-CoA (Danio rerio)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Danio rerio)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Danio rerio)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Danio rerio)
CoA-SH [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Danio rerio)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Danio rerio)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Danio rerio)
CoA-SH [cytosol]
ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Danio rerio)
CoA-SH [cytosol]
Ketone body metabolism (Danio rerio)
Synthesis of Ketone Bodies (Danio rerio)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Danio rerio)
CoA-SH [cytosol]
Metabolism of steroids (Danio rerio)
Bile acid and bile salt metabolism (Danio rerio)
Recycling of bile acids and salts (Danio rerio)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts (Danio rerio)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Danio rerio)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Danio rerio)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
CoA-SH [cytosol]
Cholesterol biosynthesis (Danio rerio)
ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Danio rerio)
CoA-SH [cytosol]
HMGCR dimer reduces bHMG-CoA to MVA (Danio rerio)
CoA-SH [cytosol]
Phospholipid metabolism (Danio rerio)
Glycerophospholipid biosynthesis (Danio rerio)
Acyl chain remodeling of CL (Danio rerio)
DLCL is acylated to MLCL by LCLAT1 (ER) (Danio rerio)
CoA-SH [cytosol]
MLCL is acylated to CL by LCLAT1 (ER) (Danio rerio)
CoA-SH [cytosol]
Acyl chain remodeling of DAG and TAG (Danio rerio)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Danio rerio)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Danio rerio)
CoA-SH [cytosol]
DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Danio rerio)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Danio rerio)
1-acyl LPC is acylated to PC by LPCAT (Danio rerio)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Danio rerio)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Danio rerio)
1-acyl LPG is acylated to PG by LPGAT (Danio rerio)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Danio rerio)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Danio rerio)
1-acyl LPI is acylated to PI by MBOAT7 (Danio rerio)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Danio rerio)
CoA-SH [cytosol]
Synthesis of PA (Danio rerio)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Danio rerio)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Danio rerio)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Danio rerio)
CoA-SH [cytosol]
Synthesis of PC (Danio rerio)
Cho is acetylated to AcCho by CHAT (Danio rerio)
CoA-SH [cytosol]
Sphingolipid metabolism (Danio rerio)
Sphingolipid de novo biosynthesis (Danio rerio)
Ceramide synthases transfer acyl-CoA onto sphingoid (Danio rerio)
CoA-SH [cytosol]
SPTLC complexes transfer acyl-CoA onto serine (Danio rerio)
CoA-SH [cytosol]
Triglyceride metabolism (Danio rerio)
Triglyceride biosynthesis (Danio rerio)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Danio rerio)
CoA-SH [cytosol]
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Danio rerio)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Danio rerio)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Danio rerio)
Wax biosynthesis (Danio rerio)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Danio rerio)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Danio rerio)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Danio rerio)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Vitamin B5 (pantothenate) metabolism (Danio rerio)
Coenzyme A biosynthesis (Danio rerio)
COASY phosphorylates DP-CoA (Danio rerio)
CoA-SH [cytosol]
DCAKD phosphorylates DP-CoA (Danio rerio)
CoA-SH [cytosol]
SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Danio rerio)
CoA-SH [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Danio rerio)
CoA-SH [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
Synthesis of substrates in N-glycan biosythesis (Danio rerio)
Synthesis of UDP-N-acetyl-glucosamine (Danio rerio)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Danio rerio)
CoA-SH [cytosol]
Surfactant metabolism (Danio rerio)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Danio rerio)
CoA-SH [cytosol]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter release cycle (Danio rerio)
Acetylcholine Neurotransmitter Release Cycle (Danio rerio)
Cho is acetylated to AcCho by CHAT (Danio rerio)
CoA-SH [cytosol]
Sensory Perception (Danio rerio)
Visual phototransduction (Danio rerio)
The phototransduction cascade (Danio rerio)
Inactivation, recovery and regulation of the phototransduction cascade (Danio rerio)
NMT1/2 transfer MYS to GNAT1 (Danio rerio)
CoA-SH [cytosol]
The retinoid cycle in cones (daylight vision) (Danio rerio)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Danio rerio)
CoA-SH [cytosol]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Extra-nuclear estrogen signaling (Danio rerio)
ZDHHC7, ZDHHC21 palmitoylate ESR1 (Danio rerio)
CoA-SH [cytosol]
Transport of small molecules (Danio rerio)
Plasma lipoprotein assembly, remodeling, and clearance (Danio rerio)
Plasma lipoprotein assembly (Danio rerio)
HDL assembly (Danio rerio)
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Danio rerio)
CoA-SH [cytosol]
Plasma lipoprotein clearance (Danio rerio)
LDL clearance (Danio rerio)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Danio rerio)
CoA-SH [cytosol]
Vesicle-mediated transport (Danio rerio)
Membrane Trafficking (Danio rerio)
Intra-Golgi and retrograde Golgi-to-ER traffic (Danio rerio)
Golgi-to-ER retrograde transport (Danio rerio)
COPI-independent Golgi-to-ER retrograde traffic (Danio rerio)
LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Danio rerio)
CoA-SH [cytosol]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
M Phase (Dictyostelium discoideum)
Mitotic Prometaphase (Dictyostelium discoideum)
Resolution of Sister Chromatid Cohesion (Dictyostelium discoideum)
Deacetylation of cohesin (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Ethanol oxidation (Dictyostelium discoideum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Metabolism of polyamines (Dictyostelium discoideum)
Interconversion of polyamines (Dictyostelium discoideum)
Spermidine => N-acetylated spermidine (Dictyostelium discoideum)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glycosaminoglycan metabolism (Dictyostelium discoideum)
Heparan sulfate/heparin (HS-GAG) metabolism (Dictyostelium discoideum)
HS-GAG degradation (Dictyostelium discoideum)
HGSNAT oligomer acetylates Heparan chain(1) (Dictyostelium discoideum)
CoA-SH [cytosol]
HGSNAT oligomer acetylates Heparan sulfate chain(3) (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Fatty acyl-CoA biosynthesis (Dictyostelium discoideum)
ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Dictyostelium discoideum)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Dictyostelium discoideum)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
Mitochondrial Fatty Acid Beta-Oxidation (Dictyostelium discoideum)
Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
Peroxisomal lipid metabolism (Dictyostelium discoideum)
Beta-oxidation of very long chain fatty acids (Dictyostelium discoideum)
Peroxisomal uptake of very long-chain fatty acyl CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of steroids (Dictyostelium discoideum)
Cholesterol biosynthesis (Dictyostelium discoideum)
ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
HMGCR dimer reduces bHMG-CoA to MVA (Dictyostelium discoideum)
CoA-SH [cytosol]
HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
Phospholipid metabolism (Dictyostelium discoideum)
Glycerophospholipid biosynthesis (Dictyostelium discoideum)
Acyl chain remodeling of CL (Dictyostelium discoideum)
DLCL is acylated to MLCL by LCLAT1 (ER) (Dictyostelium discoideum)
CoA-SH [cytosol]
MLCL is acylated to CL by LCLAT1 (ER) (Dictyostelium discoideum)
CoA-SH [cytosol]
Acyl chain remodeling of DAG and TAG (Dictyostelium discoideum)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Dictyostelium discoideum)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Dictyostelium discoideum)
CoA-SH [cytosol]
DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Dictyostelium discoideum)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Dictyostelium discoideum)
1-acyl LPC is acylated to PC by LPCAT (Dictyostelium discoideum)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Dictyostelium discoideum)
CoA-SH [cytosol]
Acyl chain remodelling of PE (Dictyostelium discoideum)
1-acyl LPE is acylated to PE by LPEAT (Dictyostelium discoideum)
CoA-SH [cytosol]
2-acyl LPE is acylated to PE by LPEAT (Dictyostelium discoideum)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Dictyostelium discoideum)
1-acyl LPG is acylated to PG by LPGAT (Dictyostelium discoideum)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Dictyostelium discoideum)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Dictyostelium discoideum)
1-acyl LPI is acylated to PI by MBOAT7 (Dictyostelium discoideum)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Dictyostelium discoideum)
CoA-SH [cytosol]
Acyl chain remodelling of PS (Dictyostelium discoideum)
1-acyl LPS is acylated to PS by LPSAT (Dictyostelium discoideum)
CoA-SH [cytosol]
2-acyl LPS is acylated to PS by LPSAT (Dictyostelium discoideum)
CoA-SH [cytosol]
Synthesis of PA (Dictyostelium discoideum)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Dictyostelium discoideum)
CoA-SH [cytosol]
1-acyl LPA is acylated to PA by AGPAT5 (OM) (Dictyostelium discoideum)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Dictyostelium discoideum)
CoA-SH [cytosol]
Sphingolipid metabolism (Dictyostelium discoideum)
Sphingolipid de novo biosynthesis (Dictyostelium discoideum)
Ceramide synthases transfer acyl-CoA onto sphingoid (Dictyostelium discoideum)
CoA-SH [cytosol]
Triglyceride metabolism (Dictyostelium discoideum)
Triglyceride biosynthesis (Dictyostelium discoideum)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Dictyostelium discoideum)
CoA-SH [cytosol]
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Dictyostelium discoideum)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Dictyostelium discoideum)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Dictyostelium discoideum)
Wax biosynthesis (Dictyostelium discoideum)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Dictyostelium discoideum)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Dictyostelium discoideum)
CoA-SH [cytosol]
FAR1 reduces PalmCoA to HXOL (Dictyostelium discoideum)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Dictyostelium discoideum)
eNOS activation (Dictyostelium discoideum)
Palmitoylation of eNOS (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Vitamin B5 (pantothenate) metabolism (Dictyostelium discoideum)
Coenzyme A biosynthesis (Dictyostelium discoideum)
COASY phosphorylates DP-CoA (Dictyostelium discoideum)
CoA-SH [cytosol]
Phosphopantetheine conjugation of the ACP domain of FAS (Dictyostelium discoideum)
CoA-SH [cytosol]
SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
Synthesis of substrates in N-glycan biosythesis (Dictyostelium discoideum)
Synthesis of UDP-N-acetyl-glucosamine (Dictyostelium discoideum)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Dictyostelium discoideum)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Dictyostelium discoideum)
Synthesis of glycosylphosphatidylinositol (GPI) (Dictyostelium discoideum)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Dictyostelium discoideum)
CoA-SH [cytosol]
Organelle biogenesis and maintenance (Dictyostelium discoideum)
Cilium Assembly (Dictyostelium discoideum)
HDAC6 deacetylates microtubules (Dictyostelium discoideum)
CoA-SH [cytosol]
Sensory Perception (Dictyostelium discoideum)
Visual phototransduction (Dictyostelium discoideum)
The phototransduction cascade (Dictyostelium discoideum)
Inactivation, recovery and regulation of the phototransduction cascade (Dictyostelium discoideum)
NMT1/2 transfer MYS to GNAT1 (Dictyostelium discoideum)
CoA-SH [cytosol]
The retinoid cycle in cones (daylight vision) (Dictyostelium discoideum)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Dictyostelium discoideum)
CoA-SH [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Ethanol oxidation (Drosophila melanogaster)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Drosophila melanogaster)
CoA-SH [cytosol]
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Free fatty acids regulate insulin secretion (Drosophila melanogaster)
Intracellular metabolism of fatty acids regulates insulin secretion (Drosophila melanogaster)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Drosophila melanogaster)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Metabolism of polyamines (Drosophila melanogaster)
Interconversion of polyamines (Drosophila melanogaster)
Spermidine => N-acetylated spermidine (Drosophila melanogaster)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Drosophila melanogaster)
CoA-SH [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Glycosaminoglycan metabolism (Drosophila melanogaster)
Heparan sulfate/heparin (HS-GAG) metabolism (Drosophila melanogaster)
HS-GAG degradation (Drosophila melanogaster)
HGSNAT oligomer acetylates Heparan chain(1) (Drosophila melanogaster)
CoA-SH [cytosol]
HGSNAT oligomer acetylates Heparan sulfate chain(3) (Drosophila melanogaster)
CoA-SH [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine shuttle (Drosophila melanogaster)
CPT1A transfers PALM to CAR (Drosophila melanogaster)
CoA-SH [cytosol]
CPT1B transfers PALM to CAR (Drosophila melanogaster)
CoA-SH [cytosol]
Fatty acyl-CoA biosynthesis (Drosophila melanogaster)
ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Drosophila melanogaster)
CoA-SH [cytosol]
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Drosophila melanogaster)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
Mitochondrial Fatty Acid Beta-Oxidation (Drosophila melanogaster)
Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
Peroxisomal lipid metabolism (Drosophila melanogaster)
Beta-oxidation of very long chain fatty acids (Drosophila melanogaster)
Peroxisomal uptake of very long-chain fatty acyl CoA (Drosophila melanogaster)
CoA-SH [cytosol]
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Recycling of bile acids and salts (Drosophila melanogaster)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts (Drosophila melanogaster)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Drosophila melanogaster)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
CoA-SH [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Drosophila melanogaster)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
CoA-SH [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
CoA-SH [cytosol]
Cholesterol biosynthesis (Drosophila melanogaster)
ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
HMGCR dimer reduces bHMG-CoA to MVA (Drosophila melanogaster)
CoA-SH [cytosol]
HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
Phospholipid metabolism (Drosophila melanogaster)
Glycerophospholipid biosynthesis (Drosophila melanogaster)
Acyl chain remodeling of DAG and TAG (Drosophila melanogaster)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Drosophila melanogaster)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Drosophila melanogaster)
CoA-SH [cytosol]
DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Drosophila melanogaster)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Drosophila melanogaster)
1-acyl LPC is acylated to PC by LPCAT (Drosophila melanogaster)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Drosophila melanogaster)
CoA-SH [cytosol]
Acyl chain remodelling of PE (Drosophila melanogaster)
1-acyl LPE is acylated to PE by LPEAT (Drosophila melanogaster)
CoA-SH [cytosol]
2-acyl LPE is acylated to PE by LPEAT (Drosophila melanogaster)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Drosophila melanogaster)
1-acyl LPG is acylated to PG by LPGAT (Drosophila melanogaster)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Drosophila melanogaster)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Drosophila melanogaster)
1-acyl LPI is acylated to PI by MBOAT7 (Drosophila melanogaster)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Drosophila melanogaster)
CoA-SH [cytosol]
Acyl chain remodelling of PS (Drosophila melanogaster)
1-acyl LPS is acylated to PS by LPSAT (Drosophila melanogaster)
CoA-SH [cytosol]
2-acyl LPS is acylated to PS by LPSAT (Drosophila melanogaster)
CoA-SH [cytosol]
Synthesis of PA (Drosophila melanogaster)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Drosophila melanogaster)
CoA-SH [cytosol]
DHAP is converted to 1-acyl GO3P by GNPAT (Drosophila melanogaster)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Drosophila melanogaster)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Drosophila melanogaster)
CoA-SH [cytosol]
Synthesis of PC (Drosophila melanogaster)
Cho is acetylated to AcCho by CHAT (Drosophila melanogaster)
CoA-SH [cytosol]
Sphingolipid metabolism (Drosophila melanogaster)
Sphingolipid de novo biosynthesis (Drosophila melanogaster)
Ceramide synthases transfer acyl-CoA onto sphingoid (Drosophila melanogaster)
CoA-SH [cytosol]
SPTLC complexes transfer acyl-CoA onto serine (Drosophila melanogaster)
CoA-SH [cytosol]
Triglyceride metabolism (Drosophila melanogaster)
Triglyceride biosynthesis (Drosophila melanogaster)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Drosophila melanogaster)
CoA-SH [cytosol]
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Drosophila melanogaster)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Drosophila melanogaster)
CoA-SH [cytosol]
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Drosophila melanogaster)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Drosophila melanogaster)
Wax biosynthesis (Drosophila melanogaster)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Drosophila melanogaster)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Drosophila melanogaster)
CoA-SH [cytosol]
FAR1 reduces PalmCoA to HXOL (Drosophila melanogaster)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Drosophila melanogaster)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Vitamin B5 (pantothenate) metabolism (Drosophila melanogaster)
Coenzyme A biosynthesis (Drosophila melanogaster)
DCAKD phosphorylates DP-CoA (Drosophila melanogaster)
CoA-SH [cytosol]
PANK2 phosphorylates PanK (Drosophila melanogaster)
CoA-SH [cytosol]
Phosphopantetheine conjugation of the ACP domain of FAS (Drosophila melanogaster)
CoA-SH [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Drosophila melanogaster)
CoA-SH [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
Synthesis of substrates in N-glycan biosythesis (Drosophila melanogaster)
Synthesis of UDP-N-acetyl-glucosamine (Drosophila melanogaster)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Drosophila melanogaster)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Drosophila melanogaster)
Synthesis of glycosylphosphatidylinositol (GPI) (Drosophila melanogaster)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Drosophila melanogaster)
CoA-SH [cytosol]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter release cycle (Drosophila melanogaster)
Acetylcholine Neurotransmitter Release Cycle (Drosophila melanogaster)
Cho is acetylated to AcCho by CHAT (Drosophila melanogaster)
CoA-SH [cytosol]
Sensory Perception (Drosophila melanogaster)
Visual phototransduction (Drosophila melanogaster)
The retinoid cycle in cones (daylight vision) (Drosophila melanogaster)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Drosophila melanogaster)
CoA-SH [cytosol]
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS processing (Drosophila melanogaster)
S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Drosophila melanogaster)
CoA-SH [cytosol]
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
ZDHHC7, ZDHHC21 palmitoylate ESR1 (Drosophila melanogaster)
CoA-SH [cytosol]
Transport of small molecules (Drosophila melanogaster)
Plasma lipoprotein assembly, remodeling, and clearance (Drosophila melanogaster)
Plasma lipoprotein assembly (Drosophila melanogaster)
HDL assembly (Drosophila melanogaster)
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Drosophila melanogaster)
CoA-SH [cytosol]
Plasma lipoprotein clearance (Drosophila melanogaster)
LDL clearance (Drosophila melanogaster)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Drosophila melanogaster)
CoA-SH [cytosol]
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Intra-Golgi and retrograde Golgi-to-ER traffic (Drosophila melanogaster)
Golgi-to-ER retrograde transport (Drosophila melanogaster)
COPI-independent Golgi-to-ER retrograde traffic (Drosophila melanogaster)
LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Drosophila melanogaster)
CoA-SH [cytosol]
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Metaphase and Anaphase (Gallus gallus)
Mitotic Anaphase (Gallus gallus)
Separation of Sister Chromatids (Gallus gallus)
Deacetylation of cleaved cohesin (Gallus gallus)
CoA-SH [cytosol]
Mitotic Prometaphase (Gallus gallus)
Resolution of Sister Chromatid Cohesion (Gallus gallus)
Deacetylation of cohesin (Gallus gallus)
CoA-SH [cytosol]
Drug ADME (Gallus gallus)
Paracetamol ADME (Gallus gallus)
NAT1,2 acetylate APAP-Cys to APAP-Mer (Gallus gallus)
CoA-SH [cytosol]
Metabolism (Gallus gallus)
Lipid metabolism (Gallus gallus)
Sphingolipid metabolism (Gallus gallus)
palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 (Gallus gallus)
CoA-SH [cytosol]
sphinganine + stearyl-CoA => dihydroceramide + CoASH (Gallus gallus)
CoA-SH [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
Synthesis of substrates in N-glycan biosythesis (Gallus gallus)
Synthesis of UDP-N-acetyl-glucosamine (Gallus gallus)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Gallus gallus)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Gallus gallus)
Synthesis of glycosylphosphatidylinositol (GPI) (Gallus gallus)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Gallus gallus)
CoA-SH [cytosol]
Surfactant metabolism (Gallus gallus)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Gallus gallus)
CoA-SH [cytosol]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter release cycle (Gallus gallus)
Acetylcholine Neurotransmitter Release Cycle (Gallus gallus)
Cho is acetylated to AcCho by CHAT (Gallus gallus)
CoA-SH [cytosol]
Sensory Perception (Gallus gallus)
Visual phototransduction (Gallus gallus)
The retinoid cycle in cones (daylight vision) (Gallus gallus)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Gallus gallus)
CoA-SH [cytosol]
Signal Transduction (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS processing (Gallus gallus)
S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Gallus gallus)
CoA-SH [cytosol]
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
ZDHHC7, ZDHHC21 palmitoylate ESR1 (Gallus gallus)
CoA-SH [cytosol]
Transport of small molecules (Gallus gallus)
Plasma lipoprotein assembly, remodeling, and clearance (Gallus gallus)
Plasma lipoprotein assembly (Gallus gallus)
HDL assembly (Gallus gallus)
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Gallus gallus)
CoA-SH [cytosol]
Plasma lipoprotein clearance (Gallus gallus)
LDL clearance (Gallus gallus)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Gallus gallus)
CoA-SH [cytosol]
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
Intra-Golgi and retrograde Golgi-to-ER traffic (Gallus gallus)
Golgi-to-ER retrograde transport (Gallus gallus)
COPI-independent Golgi-to-ER retrograde traffic (Gallus gallus)
LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Gallus gallus)
CoA-SH [cytosol]
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Separation of Sister Chromatids (Homo sapiens)
Deacetylation of cleaved cohesin (Homo sapiens)
CoA-SH [cytosol]
Mitotic Prometaphase (Homo sapiens)
Resolution of Sister Chromatid Cohesion (Homo sapiens)
Deacetylation of cohesin (Homo sapiens)
CoA-SH [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Response of Mtb to phagocytosis (Homo sapiens)
Suppression of autophagy (Homo sapiens)
Eis acetylates DUSP16 (Homo sapiens)
CoA-SH [cytosol]
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
N-myristoylation of GAG polyprotein by NMT2 (Homo sapiens)
CoA-SH [cytosol]
Myristoylation of Nef (Homo sapiens)
CoA-SH [cytosol]
Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
Respiratory syncytial virus (RSV) genome replication, transcription and translation (Homo sapiens)
Maturation of hRSV A proteins (Homo sapiens)
F0 is palmitoylated (Homo sapiens)
CoA-SH [cytosol]
G is palmitoylated (Homo sapiens)
CoA-SH [cytosol]
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
CREBBP acetylates SARS-CoV-2 N at K375 (Homo sapiens)
CoA-SH [cytosol]
Drug ADME (Homo sapiens)
Paracetamol ADME (Homo sapiens)
NAT1,2 acetylate APAP-Cys to APAP-Mer (Homo sapiens)
CoA-SH [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Aflatoxin activation and detoxification (Homo sapiens)
Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C (Homo sapiens)
CoA-SH [cytosol]
Phase I - Functionalization of compounds (Homo sapiens)
Ethanol oxidation (Homo sapiens)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Homo sapiens)
CoA-SH [cytosol]
Phase II - Conjugation of compounds (Homo sapiens)
Acetylation (Homo sapiens)
The acetyl group from acetyl-CoA is transferred to the NAT1 (Homo sapiens)
CoA-SH [cytosol]
The acetyl group from acetyl-CoA is transferred to the NAT2 (Homo sapiens)
CoA-SH [cytosol]
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Free fatty acids regulate insulin secretion (Homo sapiens)
Intracellular metabolism of fatty acids regulates insulin secretion (Homo sapiens)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Homo sapiens)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Serotonin and melatonin biosynthesis (Homo sapiens)
N-acetylation of serotonin (Homo sapiens)
CoA-SH [cytosol]
Metabolism of polyamines (Homo sapiens)
Interconversion of polyamines (Homo sapiens)
Spermidine => N-acetylated spermidine (Homo sapiens)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Homo sapiens)
CoA-SH [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG degradation (Homo sapiens)
HGSNAT oligomer acetylates Heparan chain(1) (Homo sapiens)
CoA-SH [cytosol]
HGSNAT oligomer acetylates Heparan sulfate chain(3) (Homo sapiens)
CoA-SH [cytosol]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine shuttle (Homo sapiens)
CPT1A transfers PALM to CAR (Homo sapiens)
CoA-SH [cytosol]
CPT1B transfers PALM to CAR (Homo sapiens)
CoA-SH [cytosol]
Fatty acyl-CoA biosynthesis (Homo sapiens)
ACLY tetramer transforms CIT to Ac-CoA (Homo sapiens)
CoA-SH [cytosol]
Conversion of malonyl-CoA and acetyl-CoA to palmitate (Homo sapiens)
CoA-SH [cytosol]
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Homo sapiens)
CoA-SH [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Homo sapiens)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Homo sapiens)
CoA-SH [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Homo sapiens)
CoA-SH [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Homo sapiens)
CoA-SH [cytosol]
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Homo sapiens)
CoA-SH [cytosol]
ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA (Homo sapiens)
CoA-SH [cytosol]
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Homo sapiens)
CoA-SH [cytosol]
ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Homo sapiens)
CoA-SH [cytosol]
Mitochondrial Fatty Acid Beta-Oxidation (Homo sapiens)
Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Homo sapiens)
CoA-SH [cytosol]
Peroxisomal lipid metabolism (Homo sapiens)
Beta-oxidation of very long chain fatty acids (Homo sapiens)
Peroxisomal uptake of very long-chain fatty acyl CoA (Homo sapiens)
CoA-SH [cytosol]
Ketone body metabolism (Homo sapiens)
Synthesis of Ketone Bodies (Homo sapiens)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Homo sapiens)
CoA-SH [cytosol]
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Homo sapiens)
CoA-SH [cytosol]
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Homo sapiens)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
CoA-SH [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
CoA-SH [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
CoA-SH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
CoA-SH [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
CoA-SH [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
CoA-SH [cytosol]
Cholesterol biosynthesis (Homo sapiens)
ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Homo sapiens)
CoA-SH [cytosol]
HMGCR dimer reduces bHMG-CoA to MVA (Homo sapiens)
CoA-SH [cytosol]
HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Homo sapiens)
CoA-SH [cytosol]
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodeling of CL (Homo sapiens)
DLCL is acylated to MLCL by LCLAT1 (ER) (Homo sapiens)
CoA-SH [cytosol]
MLCL is acylated to CL by LCLAT1 (ER) (Homo sapiens)
CoA-SH [cytosol]
Acyl chain remodeling of DAG and TAG (Homo sapiens)
AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Homo sapiens)
CoA-SH [cytosol]
DAG is acylated to TAG by DGAT1/2 (Homo sapiens)
CoA-SH [cytosol]
DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Homo sapiens)
CoA-SH [cytosol]
Acyl chain remodelling of PC (Homo sapiens)
1-acyl LPC is acylated to PC by LPCAT (Homo sapiens)
CoA-SH [cytosol]
2-acyl LPC is acylated to PC by LPCAT (Homo sapiens)
CoA-SH [cytosol]
Acyl chain remodelling of PE (Homo sapiens)
1-acyl LPE is acylated to PE by LPEAT (Homo sapiens)
CoA-SH [cytosol]
2-acyl LPE is acylated to PE by LPEAT (Homo sapiens)
CoA-SH [cytosol]
Acyl chain remodelling of PG (Homo sapiens)
1-acyl LPG is acylated to PG by LPGAT (Homo sapiens)
CoA-SH [cytosol]
2-acyl LPG is acylated to PG by LPGAT (Homo sapiens)
CoA-SH [cytosol]
Acyl chain remodelling of PI (Homo sapiens)
1-acyl LPI is acylated to PI by MBOAT7 (Homo sapiens)
CoA-SH [cytosol]
2-acyl LPI is acylated to PI by MBOAT7 (Homo sapiens)
CoA-SH [cytosol]
Acyl chain remodelling of PS (Homo sapiens)
1-acyl LPS is acylated to PS by LPSAT (Homo sapiens)
CoA-SH [cytosol]
2-acyl LPS is acylated to PS by LPSAT (Homo sapiens)
CoA-SH [cytosol]
Synthesis of PA (Homo sapiens)
1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Homo sapiens)
CoA-SH [cytosol]
1-acyl LPA is acylated to PA by AGPAT5 (OM) (Homo sapiens)
CoA-SH [cytosol]
DHAP is converted to 1-acyl GO3P by GNPAT (Homo sapiens)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by AGPAT6 (Homo sapiens)
CoA-SH [cytosol]
G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Homo sapiens)
CoA-SH [cytosol]
Synthesis of PC (Homo sapiens)
Cho is acetylated to AcCho by CHAT (Homo sapiens)
CoA-SH [cytosol]
Sphingolipid metabolism (Homo sapiens)
Sphingolipid de novo biosynthesis (Homo sapiens)
Ceramide synthases transfer acyl-CoA onto sphingoid (Homo sapiens)
CoA-SH [cytosol]
SPTLC complexes transfer acyl-CoA onto serine (Homo sapiens)
CoA-SH [cytosol]
Triglyceride metabolism (Homo sapiens)
Triglyceride biosynthesis (Homo sapiens)
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Homo sapiens)
CoA-SH [cytosol]
1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Homo sapiens)
CoA-SH [cytosol]
MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Homo sapiens)
CoA-SH [cytosol]
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Homo sapiens)
CoA-SH [cytosol]
Wax and plasmalogen biosynthesis (Homo sapiens)
Wax biosynthesis (Homo sapiens)
AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Homo sapiens)
CoA-SH [cytosol]
AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Homo sapiens)
CoA-SH [cytosol]
FAR1 reduces PalmCoA to HXOL (Homo sapiens)
CoA-SH [cytosol]
FAR2 reduces PalmCoA to HXOL (Homo sapiens)
CoA-SH [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
eNOS activation (Homo sapiens)
N-myristoylation of eNOS (Homo sapiens)
CoA-SH [cytosol]
Palmitoylation of eNOS (Homo sapiens)
CoA-SH [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Vitamin B5 (pantothenate) metabolism (Homo sapiens)
Coenzyme A biosynthesis (Homo sapiens)
COASY phosphorylates DP-CoA (Homo sapiens)
CoA-SH [cytosol]
DCAKD phosphorylates DP-CoA (Homo sapiens)
CoA-SH [cytosol]
PANK2 phosphorylates PanK (Homo sapiens)
CoA-SH [cytosol]
Phosphopantetheine conjugation of the ACP domain of FAS (Homo sapiens)
CoA-SH [cytosol]
SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Homo sapiens)
CoA-SH [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Homo sapiens)
CoA-SH [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
Synthesis of UDP-N-acetyl-glucosamine (Homo sapiens)
Acetylation of glucosamine 6-phosphate to GlcNAc6P (Homo sapiens)
CoA-SH [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
Synthesis of glycosylphosphatidylinositol (GPI) (Homo sapiens)
glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Homo sapiens)
CoA-SH [cytosol]
Surfactant metabolism (Homo sapiens)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Homo sapiens)
CoA-SH [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
Acetylcholine Neurotransmitter Release Cycle (Homo sapiens)
Cho is acetylated to AcCho by CHAT (Homo sapiens)
CoA-SH [cytosol]
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
ATAT acetylates microtubules (Homo sapiens)
CoA-SH [cytosol]
HDAC6 deacetylates microtubules (Homo sapiens)
CoA-SH [cytosol]
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
NMT1/2 transfer MYS to GNAT1 (Homo sapiens)
CoA-SH [cytosol]
Unknown NAT N-acylates Gly in GNAT1 (Homo sapiens)
CoA-SH [cytosol]
The retinoid cycle in cones (daylight vision) (Homo sapiens)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Homo sapiens)
CoA-SH [cytosol]
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS processing (Homo sapiens)
S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Homo sapiens)
CoA-SH [cytosol]
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
ZDHHC7, ZDHHC21 palmitoylate ESR1 (Homo sapiens)
CoA-SH [cytosol]
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein assembly (Homo sapiens)
HDL assembly (Homo sapiens)
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Homo sapiens)
CoA-SH [cytosol]
Plasma lipoprotein clearance (Homo sapiens)
LDL clearance (Homo sapiens)
SOAT1,2 transfer acyl group to CHOL forming CHEST (Homo sapiens)
CoA-SH [cytosol]
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-independent Golgi-to-ER retrograde traffic (Homo sapiens)
LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Homo sapiens)
CoA-SH [cytosol]
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
NatC acetylates ARFFRP1 (Homo sapiens)
CoA-SH [cytosol]
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Deacetylation of cleaved cohesin (Mus musculus)
CoA-SH [cytosol]
Mitotic Prometaphase (Mus musculus)
Resolution of Sister Chromatid Cohesion (Mus musculus)
Deacetylation of cohesin (Mus musculus)
CoA-SH [cytosol]
Drug ADME (Mus musculus)
Paracetamol ADME (Mus musculus)
NAT1,2 acetylate APAP-Cys to APAP-Mer (Mus musculus)
CoA-SH [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Ethanol oxidation (Mus musculus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Mus musculus)
CoA-SH [cytosol]
Phase II - Conjugation of compounds (Mus musculus)
Acetylation (Mus musculus)
The acetyl group from acetyl-CoA is transferred to the NAT1 (Mus musculus)
CoA-SH [cytosol]
The acetyl group from acetyl-CoA is transferred to the NAT2 (Mus musculus)
CoA-SH [cytosol]
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Free fatty acids regulate insulin secretion (Mus musculus)
Intracellular metabolism of fatty acids regulates insulin secretion (Mus musculus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Mus musculus)
CoA-SH [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of amine-derived hormones (Mus musculus)
Serotonin and melatonin biosynthesis (Mus musculus)
N-acetylation of serotonin (Mus musculus)
CoA-SH [cytosol]
Metabolism of polyamines (Mus musculus)
Interconversion of polyamines (Mus musculus)
Spermidine => N-acetylated spermidine (Mus musculus)
CoA-SH [cytosol]
Spermine => N-acetylated spermine (Mus musculus)
CoA-SH [cytosol]
Metabolism of carbohydrates (Mus musculus)
Glycosaminoglycan metabolism (Mus musculus)
Heparan sulfate/heparin (HS-GAG) metabolism (Mus musculus)
HS-GAG degradation (Mus musculus)
HGSNAT oligomer acetylates Heparan chain(1) (Mus musculus)
CoA-SH [cytosol]
HGSNAT oligomer acetylates Heparan sulfate chain(3) (Mus musculus)
CoA-SH [cytosol]
![CoA-SH [cytosol] icon](/icon/R-ICO-013878.svg){kind=icon}