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27-OH-CHOL [nucleoplasm]
Stable Identifier
R-ALL-9024328
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
27-hydroxycholesterol, 5-cholestene-3beta,27-diol, (25R)-cholest-5-ene-3beta,26-diol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
27-hydroxysterol binds ESR1, ESR2 (Bos taurus)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Bos taurus)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Bos taurus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Bos taurus)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Bos taurus)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Bos taurus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Bos taurus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
27-hydroxysterol binds ESR1, ESR2 (Canis familiaris)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Canis familiaris)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Canis familiaris)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Canis familiaris)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Canis familiaris)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Canis familiaris)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Canis familiaris)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Canis familiaris)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Canis familiaris)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Canis familiaris)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Canis familiaris)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
27-hydroxysterol binds ESR1, ESR2 (Danio rerio)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Danio rerio)
27-OH-CHOL [nucleoplasm]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
27-hydroxysterol binds ESR1, ESR2 (Drosophila melanogaster)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Drosophila melanogaster)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Drosophila melanogaster)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Drosophila melanogaster)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Drosophila melanogaster)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Drosophila melanogaster)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Drosophila melanogaster)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
27-hydroxysterol binds ESR1, ESR2 (Gallus gallus)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Gallus gallus)
27-OH-CHOL [nucleoplasm]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
27-hydroxysterol binds ESR1, ESR2 (Homo sapiens)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Homo sapiens)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Homo sapiens)
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis (Homo sapiens)
Expression of PCK1 regulated by NR1H3 (Homo sapiens)
NRIP1:NR1H3:RXR:NR1H3 ligand:PCK1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3, NRIP1 bind the PCK1 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NRIP1:NR1H3:RXR:NR1H3 ligand:PCK1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis (Homo sapiens)
Expression of ANGPTL3 regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:ANGPTL3 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of FASN regulated by NR1H2 or NR1H3 (Homo sapiens)
NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:FASN gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of SCD regulated by NR1H2 or NR1H3 (Homo sapiens)
NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:SCD gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 (Homo sapiens)
NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:SREBF1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2 or NR1H3, NRIP1 bind the SCD gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:SCD gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:SREBF1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the ANGPTL3 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:ANGPTL3 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3, NRIP1 bind the FASN gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:FASN gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose (Homo sapiens)
Expression of PLIN1 regulated by NR1H2 or NR1H3 (Homo sapiens)
PLIN1 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the PLIN1 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
PLIN1 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Homo sapiens)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Homo sapiens)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of FABP6 regulated by NR1H2,3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:FABP6 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of UGT1A3 (Homo sapiens)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Homo sapiens)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the FABP6 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:FABP6 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake (Homo sapiens)
Expression of MYLIP regulated by NR1H2,3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:MYLIP gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the MYLIP gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:MYLIP gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Homo sapiens)
ABCA1 gene transcription regulated by NR1H2 or NR1H3 (Homo sapiens)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Homo sapiens)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Homo sapiens)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ARL4C gene transcription regulated by NR1H2,3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:ARL4C gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Homo sapiens)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of ABCG1 regulated by NR1H2,3 (Homo sapiens)
ABCG1 gene:NR1H2,3:RXR:oxysterol:GPS2:KDMs [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of ABCG5 regulated by NR1H2,3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:ABCG5 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of ABCG8 regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:ABCG8 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of APOC1 regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:APOC1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of APOC2 regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:APOC2 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of APOC4 regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:APOC4 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of APOD regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:APOD gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of APOE regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:APOE gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of CETP regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:CETP gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of EEPD1 regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:EEPD1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Expression of PLTP regulated by NR1H2 or NR1H3 (Homo sapiens)
NR1H2,3:RXR:NR1H2,3 ligand:PLTP gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Homo sapiens)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Homo sapiens)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Homo sapiens)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Homo sapiens)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Homo sapiens)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Homo sapiens)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the ABCG5 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:ABCG5 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the ABCG8 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:ABCG8 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the APOC1 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:APOC1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the APOC2 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:APOC2 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the APOC4 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:APOC4 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the APOD gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:APOD gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the APOE gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:APOE gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the ARL4C gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:ARL4C gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the CETP gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:CETP gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the EEPD1 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:EEPD1 gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the NR1H3 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 gene:LXR:RXR:LXR ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3 binds the PLTP gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H2,3:RXR:NR1H2,3 ligand:PLTP gene [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 gene transcription regulated by NR1H2,3 (Homo sapiens)
NR1H3 gene:LXR:RXR:LXR ligands [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCG1 gene:NR1H2,3:RXR:oxysterol:GPS2:KDMs [nucleoplasm] (Homo sapiens)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
27-hydroxysterol binds ESR1, ESR2 (Mus musculus)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Mus musculus)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Mus musculus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Mus musculus)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Mus musculus)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Mus musculus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Mus musculus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
27-hydroxysterol binds ESR1, ESR2 (Rattus norvegicus)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Rattus norvegicus)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Rattus norvegicus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Rattus norvegicus)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Rattus norvegicus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Rattus norvegicus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Rattus norvegicus)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Rattus norvegicus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Rattus norvegicus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Rattus norvegicus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Rattus norvegicus)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
27-hydroxysterol binds ESR1, ESR2 (Sus scrofa)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Sus scrofa)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Sus scrofa)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Sus scrofa)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Sus scrofa)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Sus scrofa)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Sus scrofa)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Sus scrofa)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Sus scrofa)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Sus scrofa)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1 recruits EP300 to the ABCA1 promoter (Sus scrofa)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Sus scrofa)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Sus scrofa)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Sus scrofa)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Sus scrofa)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
ESR-mediated signaling (Xenopus tropicalis)
27-hydroxysterol binds ESR1, ESR2 (Xenopus tropicalis)
27-OH-CHOL [nucleoplasm]
27-OH-CHOL:ESR1,2 [nucleoplasm] (Xenopus tropicalis)
27-OH-CHOL [nucleoplasm]
NR1H2 and NR1H3-mediated signaling (Xenopus tropicalis)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Xenopus tropicalis)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Xenopus tropicalis)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Xenopus tropicalis)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Xenopus tropicalis)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Xenopus tropicalis)
NR1H3, NR1H2 ligands [nucleoplasm]
27-OH-CHOL [nucleoplasm]
External Reference Information
External Reference
(25R)-cholest-5-ene-3beta,26-diol [ChEBI:76591]
Participates
as a member of
NR1H3, NR1H2 ligands [nucleoplasm]
as an input of
27-hydroxysterol binds ESR1, ESR2 (Drosophila melanogaster)
27-hydroxysterol binds ESR1, ESR2 (Gallus gallus)
27-hydroxysterol binds ESR1, ESR2 (Xenopus tropicalis)
27-hydroxysterol binds ESR1, ESR2 (Danio rerio)
27-hydroxysterol binds ESR1, ESR2 (Sus scrofa)
27-hydroxysterol binds ESR1, ESR2 (Bos taurus)
27-hydroxysterol binds ESR1, ESR2 (Canis familiaris)
27-hydroxysterol binds ESR1, ESR2 (Rattus norvegicus)
27-hydroxysterol binds ESR1, ESR2 (Mus musculus)
27-hydroxysterol binds ESR1, ESR2 (Homo sapiens)
as a component of
27-OH-CHOL:ESR1,2 [nucleoplasm] (Mus musculus)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Drosophila melanogaster)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Danio rerio)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Bos taurus)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Gallus gallus)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Xenopus tropicalis)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Canis familiaris)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Rattus norvegicus)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Sus scrofa)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Homo sapiens)
Cross References
Guide to Pharmacology - Ligands
2752
PubChem Compound
135651393
HMDB Metabolite
HMDB0002103
ZINC
000004097086
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