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What is Reactome ?
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Digital Preservation
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2OBUTA [cytosol]
Stable Identifier
R-ALL-936714
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
2-oxobutanoate, 2-oxobutanoic acid, 2-Ketobutyrate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Sulfur amino acid metabolism (Bos taurus)
Cysteine formation from homocysteine (Bos taurus)
PXLP-K212-CTH cleaves L-Cystathionine (Bos taurus)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Bos taurus)
Homocysteine is degraded to oxobutanoate and H2S (Bos taurus)
2OBUTA [cytosol]
Threonine catabolism (Bos taurus)
HRSP12 deaminates 2AA to 2OBUTA (Bos taurus)
2OBUTA [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Sulfur amino acid metabolism (Caenorhabditis elegans)
Cysteine formation from homocysteine (Caenorhabditis elegans)
PXLP-K212-CTH cleaves L-Cystathionine (Caenorhabditis elegans)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Caenorhabditis elegans)
Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)
2OBUTA [cytosol]
Threonine catabolism (Caenorhabditis elegans)
HRSP12 deaminates 2AA to 2OBUTA (Caenorhabditis elegans)
2OBUTA [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Sulfur amino acid metabolism (Canis familiaris)
Cysteine formation from homocysteine (Canis familiaris)
PXLP-K212-CTH cleaves L-Cystathionine (Canis familiaris)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Canis familiaris)
Homocysteine is degraded to oxobutanoate and H2S (Canis familiaris)
2OBUTA [cytosol]
Threonine catabolism (Canis familiaris)
HRSP12 deaminates 2AA to 2OBUTA (Canis familiaris)
2OBUTA [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Sulfur amino acid metabolism (Danio rerio)
Cysteine formation from homocysteine (Danio rerio)
PXLP-K212-CTH cleaves L-Cystathionine (Danio rerio)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Danio rerio)
Homocysteine is degraded to oxobutanoate and H2S (Danio rerio)
2OBUTA [cytosol]
Threonine catabolism (Danio rerio)
HRSP12 deaminates 2AA to 2OBUTA (Danio rerio)
2OBUTA [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Sulfur amino acid metabolism (Dictyostelium discoideum)
Cysteine formation from homocysteine (Dictyostelium discoideum)
PXLP-K212-CTH cleaves L-Cystathionine (Dictyostelium discoideum)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Dictyostelium discoideum)
Homocysteine is degraded to oxobutanoate and H2S (Dictyostelium discoideum)
2OBUTA [cytosol]
Threonine catabolism (Dictyostelium discoideum)
HRSP12 deaminates 2AA to 2OBUTA (Dictyostelium discoideum)
2OBUTA [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Sulfur amino acid metabolism (Drosophila melanogaster)
Cysteine formation from homocysteine (Drosophila melanogaster)
PXLP-K212-CTH cleaves L-Cystathionine (Drosophila melanogaster)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Drosophila melanogaster)
Homocysteine is degraded to oxobutanoate and H2S (Drosophila melanogaster)
2OBUTA [cytosol]
Threonine catabolism (Drosophila melanogaster)
HRSP12 deaminates 2AA to 2OBUTA (Drosophila melanogaster)
2OBUTA [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Sulfur amino acid metabolism (Gallus gallus)
Cysteine formation from homocysteine (Gallus gallus)
PXLP-K212-CTH cleaves L-Cystathionine (Gallus gallus)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Gallus gallus)
Homocysteine is degraded to oxobutanoate and H2S (Gallus gallus)
2OBUTA [cytosol]
Threonine catabolism (Gallus gallus)
HRSP12 deaminates 2AA to 2OBUTA (Gallus gallus)
2OBUTA [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Metabolism of ingested SeMet, Sec, MeSec into H2Se (Homo sapiens)
Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH (Homo sapiens)
2OBUTA [cytosol]
SeCysta is hydrolysed to Sec by PXLP-K212-CTH (Homo sapiens)
2OBUTA [cytosol]
Sulfur amino acid metabolism (Homo sapiens)
Cysteine formation from homocysteine (Homo sapiens)
PXLP-K212-CTH cleaves L-Cystathionine (Homo sapiens)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Homo sapiens)
Homocysteine is degraded to oxobutanoate and H2S (Homo sapiens)
2OBUTA [cytosol]
Threonine catabolism (Homo sapiens)
HRSP12 deaminates 2AA to 2OBUTA (Homo sapiens)
2OBUTA [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Sulfur amino acid metabolism (Mus musculus)
Cysteine formation from homocysteine (Mus musculus)
PXLP-K212-CTH cleaves L-Cystathionine (Mus musculus)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Mus musculus)
Homocysteine is degraded to oxobutanoate and H2S (Mus musculus)
2OBUTA [cytosol]
Threonine catabolism (Mus musculus)
HRSP12 deaminates 2AA to 2OBUTA (Mus musculus)
2OBUTA [cytosol]
Mycobacterium tuberculosis biological processes (Mycobacterium tuberculosis)
Sulfur compound metabolism (Mycobacterium tuberculosis)
Sulfur amino acid metabolism (Mycobacterium tuberculosis)
Cysteine from cystathionine and vice versa (Mycobacterium tuberculosis)
2OBUTA [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Sulfur amino acid metabolism (Rattus norvegicus)
Cysteine formation from homocysteine (Rattus norvegicus)
PXLP-K212-CTH cleaves L-Cystathionine (Rattus norvegicus)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Rattus norvegicus)
Homocysteine is degraded to oxobutanoate and H2S (Rattus norvegicus)
2OBUTA [cytosol]
Threonine catabolism (Rattus norvegicus)
HRSP12 deaminates 2AA to 2OBUTA (Rattus norvegicus)
2OBUTA [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
Cysteine formation from homocysteine (Saccharomyces cerevisiae)
PXLP-K212-CTH cleaves L-Cystathionine (Saccharomyces cerevisiae)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Saccharomyces cerevisiae)
Homocysteine is degraded to oxobutanoate and H2S (Saccharomyces cerevisiae)
2OBUTA [cytosol]
Threonine catabolism (Saccharomyces cerevisiae)
HRSP12 deaminates 2AA to 2OBUTA (Saccharomyces cerevisiae)
2OBUTA [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Sulfur amino acid metabolism (Schizosaccharomyces pombe)
Cysteine formation from homocysteine (Schizosaccharomyces pombe)
PXLP-K212-CTH cleaves L-Cystathionine (Schizosaccharomyces pombe)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Schizosaccharomyces pombe)
Homocysteine is degraded to oxobutanoate and H2S (Schizosaccharomyces pombe)
2OBUTA [cytosol]
Threonine catabolism (Schizosaccharomyces pombe)
HRSP12 deaminates 2AA to 2OBUTA (Schizosaccharomyces pombe)
2OBUTA [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Sulfur amino acid metabolism (Sus scrofa)
Cysteine formation from homocysteine (Sus scrofa)
PXLP-K212-CTH cleaves L-Cystathionine (Sus scrofa)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Sus scrofa)
Homocysteine is degraded to oxobutanoate and H2S (Sus scrofa)
2OBUTA [cytosol]
Threonine catabolism (Sus scrofa)
HRSP12 deaminates 2AA to 2OBUTA (Sus scrofa)
2OBUTA [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Sulfur amino acid metabolism (Xenopus tropicalis)
Cysteine formation from homocysteine (Xenopus tropicalis)
PXLP-K212-CTH cleaves L-Cystathionine (Xenopus tropicalis)
2OBUTA [cytosol]
Degradation of cysteine and homocysteine (Xenopus tropicalis)
Homocysteine is degraded to oxobutanoate and H2S (Xenopus tropicalis)
2OBUTA [cytosol]
Threonine catabolism (Xenopus tropicalis)
HRSP12 deaminates 2AA to 2OBUTA (Xenopus tropicalis)
2OBUTA [cytosol]
External Reference Information
External Reference
2-oxobutanoic acid [ChEBI:30831]
Participates
as an output of
Cysteine from cystathionine and vice versa (Mycobacterium tuberculosis)
Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth (Mus musculus)
HRSP12 deaminates 2AA to 2OBUTA (Mus musculus)
HRSP12 deaminates 2AA to 2OBUTA (Homo sapiens)
HRSP12 deaminates 2AA to 2OBUTA (Rattus norvegicus)
HRSP12 deaminates 2AA to 2OBUTA (Canis familiaris)
HRSP12 deaminates 2AA to 2OBUTA (Bos taurus)
HRSP12 deaminates 2AA to 2OBUTA (Sus scrofa)
HRSP12 deaminates 2AA to 2OBUTA (Danio rerio)
HRSP12 deaminates 2AA to 2OBUTA (Xenopus tropicalis)
HRSP12 deaminates 2AA to 2OBUTA (Gallus gallus)
HRSP12 deaminates 2AA to 2OBUTA (Drosophila melanogaster)
HRSP12 deaminates 2AA to 2OBUTA (Caenorhabditis elegans)
HRSP12 deaminates 2AA to 2OBUTA (Dictyostelium discoideum)
HRSP12 deaminates 2AA to 2OBUTA (Schizosaccharomyces pombe)
HRSP12 deaminates 2AA to 2OBUTA (Saccharomyces cerevisiae)
PXLP-K212-CTH cleaves L-Cystathionine (Homo sapiens)
PXLP-K212-CTH cleaves L-Cystathionine (Mus musculus)
PXLP-K212-CTH cleaves L-Cystathionine (Rattus norvegicus)
PXLP-K212-CTH cleaves L-Cystathionine (Canis familiaris)
PXLP-K212-CTH cleaves L-Cystathionine (Bos taurus)
PXLP-K212-CTH cleaves L-Cystathionine (Sus scrofa)
PXLP-K212-CTH cleaves L-Cystathionine (Danio rerio)
PXLP-K212-CTH cleaves L-Cystathionine (Xenopus tropicalis)
PXLP-K212-CTH cleaves L-Cystathionine (Gallus gallus)
PXLP-K212-CTH cleaves L-Cystathionine (Drosophila melanogaster)
PXLP-K212-CTH cleaves L-Cystathionine (Caenorhabditis elegans)
PXLP-K212-CTH cleaves L-Cystathionine (Dictyostelium discoideum)
PXLP-K212-CTH cleaves L-Cystathionine (Schizosaccharomyces pombe)
PXLP-K212-CTH cleaves L-Cystathionine (Saccharomyces cerevisiae)
Homocysteine is degraded to oxobutanoate and H2S (Gallus gallus)
Homocysteine is degraded to oxobutanoate and H2S (Homo sapiens)
Homocysteine is degraded to oxobutanoate and H2S (Mus musculus)
Homocysteine is degraded to oxobutanoate and H2S (Rattus norvegicus)
Homocysteine is degraded to oxobutanoate and H2S (Canis familiaris)
Homocysteine is degraded to oxobutanoate and H2S (Bos taurus)
Homocysteine is degraded to oxobutanoate and H2S (Sus scrofa)
Homocysteine is degraded to oxobutanoate and H2S (Danio rerio)
Homocysteine is degraded to oxobutanoate and H2S (Xenopus tropicalis)
Homocysteine is degraded to oxobutanoate and H2S (Drosophila melanogaster)
Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)
Homocysteine is degraded to oxobutanoate and H2S (Dictyostelium discoideum)
Homocysteine is degraded to oxobutanoate and H2S (Schizosaccharomyces pombe)
Homocysteine is degraded to oxobutanoate and H2S (Saccharomyces cerevisiae)
SeCysta is hydrolysed to Sec by PXLP-K212-CTH (Homo sapiens)
SeCysta is hydrolysed to Sec by PXLP-K211-Cth (Rattus norvegicus)
Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH (Homo sapiens)
Cross References
COMPOUND
C00109
HMDB Metabolite
HMDB0000005
ZINC
000001532540
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