Reactome | Cu2+ [Golgi lumen]

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Cu2+ [Golgi lumen]

Stable Identifier

R-ALL-936901

Type

Chemical Compound [SimpleEntity]

Compartment

Golgi lumen

Synonyms

Copper, copper(2+)

Locations in the PathwayBrowser

for Species:

Expand all

Cellular responses to external stimuli (Bos taurus)

- Cellular responses to stress (Bos taurus)
  - Cellular response to chemical stress (Bos taurus)
    - Detoxification of Reactive Oxygen Species (Bos taurus)
      - Secretion of SOD3 (Bos taurus)
        
        SOD3 tetramer [Golgi lumen] (Bos taurus)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Bos taurus)
        
        Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Caenorhabditis elegans)

- Cellular responses to stress (Caenorhabditis elegans)
  - Cellular response to chemical stress (Caenorhabditis elegans)
    - Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
      - Secretion of SOD3 (Caenorhabditis elegans)
        
        SOD3 tetramer [Golgi lumen] (Caenorhabditis elegans)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Caenorhabditis elegans)
        
        Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Canis familiaris)

- Cellular responses to stress (Canis familiaris)
  - Cellular response to chemical stress (Canis familiaris)
    - Detoxification of Reactive Oxygen Species (Canis familiaris)
      - Secretion of SOD3 (Canis familiaris)
        
        SOD3 tetramer [Golgi lumen] (Canis familiaris)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Canis familiaris)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Canis familiaris)

- Ion channel transport (Canis familiaris)
  - Ion transport by P-type ATPases (Canis familiaris)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Canis familiaris)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Danio rerio)

- Cellular responses to stress (Danio rerio)
  - Cellular response to chemical stress (Danio rerio)
    - Detoxification of Reactive Oxygen Species (Danio rerio)
      - Secretion of SOD3 (Danio rerio)
        
        SOD3 tetramer [Golgi lumen] (Danio rerio)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Danio rerio)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Danio rerio)

- Ion channel transport (Danio rerio)
  - Ion transport by P-type ATPases (Danio rerio)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Danio rerio)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Dictyostelium discoideum)

- Cellular responses to stress (Dictyostelium discoideum)
  - Cellular response to chemical stress (Dictyostelium discoideum)
    - Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
      - Secretion of SOD3 (Dictyostelium discoideum)
        
        SOD3 tetramer [Golgi lumen] (Dictyostelium discoideum)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Dictyostelium discoideum)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Dictyostelium discoideum)

- Ion channel transport (Dictyostelium discoideum)
  - Ion transport by P-type ATPases (Dictyostelium discoideum)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Dictyostelium discoideum)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Drosophila melanogaster)

- Cellular responses to stress (Drosophila melanogaster)
  - Cellular response to chemical stress (Drosophila melanogaster)
    - Detoxification of Reactive Oxygen Species (Drosophila melanogaster)
      - Secretion of SOD3 (Drosophila melanogaster)
        
        SOD3 tetramer [Golgi lumen] (Drosophila melanogaster)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Drosophila melanogaster)
        
        Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Gallus gallus)

- Cellular responses to stress (Gallus gallus)
  - Cellular response to chemical stress (Gallus gallus)
    - Detoxification of Reactive Oxygen Species (Gallus gallus)
      - Secretion of SOD3 (Gallus gallus)
        
        SOD3 tetramer [Golgi lumen] (Gallus gallus)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Gallus gallus)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Gallus gallus)

- Ion channel transport (Gallus gallus)
  - Ion transport by P-type ATPases (Gallus gallus)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Gallus gallus)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular response to chemical stress (Homo sapiens)
    - Detoxification of Reactive Oxygen Species (Homo sapiens)
      - ATP7A transfers Cu from ATOX1 to SOD3 (Homo sapiens)
        
        SOD3 tetramer [Golgi lumen] (Homo sapiens)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Homo sapiens)
        
        Cu2+ [Golgi lumen]
      - Secretion of SOD3 (Homo sapiens)
        
        SOD3 tetramer [Golgi lumen] (Homo sapiens)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Homo sapiens)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Homo sapiens)

- Ion channel transport (Homo sapiens)
  - Ion transport by P-type ATPases (Homo sapiens)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Homo sapiens)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Mus musculus)

- Cellular responses to stress (Mus musculus)
  - Cellular response to chemical stress (Mus musculus)
    - Detoxification of Reactive Oxygen Species (Mus musculus)
      - Secretion of SOD3 (Mus musculus)
        
        SOD3 tetramer [Golgi lumen] (Mus musculus)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Mus musculus)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Mus musculus)

- Ion channel transport (Mus musculus)
  - Ion transport by P-type ATPases (Mus musculus)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Mus musculus)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Rattus norvegicus)

- Cellular responses to stress (Rattus norvegicus)
  - Cellular response to chemical stress (Rattus norvegicus)
    - Detoxification of Reactive Oxygen Species (Rattus norvegicus)
      - Secretion of SOD3 (Rattus norvegicus)
        
        SOD3 tetramer [Golgi lumen] (Rattus norvegicus)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Rattus norvegicus)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Rattus norvegicus)

- Ion channel transport (Rattus norvegicus)
  - Ion transport by P-type ATPases (Rattus norvegicus)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Rattus norvegicus)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Saccharomyces cerevisiae)

- Cellular responses to stress (Saccharomyces cerevisiae)
  - Cellular response to chemical stress (Saccharomyces cerevisiae)
    - Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
      - Secretion of SOD3 (Saccharomyces cerevisiae)
        
        SOD3 tetramer [Golgi lumen] (Saccharomyces cerevisiae)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Saccharomyces cerevisiae)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Saccharomyces cerevisiae)

- Ion channel transport (Saccharomyces cerevisiae)
  - Ion transport by P-type ATPases (Saccharomyces cerevisiae)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Saccharomyces cerevisiae)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Schizosaccharomyces pombe)

- Cellular responses to stress (Schizosaccharomyces pombe)
  - Cellular response to chemical stress (Schizosaccharomyces pombe)
    - Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
      - Secretion of SOD3 (Schizosaccharomyces pombe)
        
        SOD3 tetramer [Golgi lumen] (Schizosaccharomyces pombe)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Schizosaccharomyces pombe)
        
        Cu2+ [Golgi lumen]

Transport of small molecules (Schizosaccharomyces pombe)

- Ion channel transport (Schizosaccharomyces pombe)
  - Ion transport by P-type ATPases (Schizosaccharomyces pombe)
    - ATP7B transports cytosolic Cu2+ to Golgi lumen (Schizosaccharomyces pombe)
      - Cu2+ [Golgi lumen]

Cellular responses to external stimuli (Sus scrofa)

- Cellular responses to stress (Sus scrofa)
  - Cellular response to chemical stress (Sus scrofa)
    - Detoxification of Reactive Oxygen Species (Sus scrofa)
      - Secretion of SOD3 (Sus scrofa)
        
        SOD3 tetramer [Golgi lumen] (Sus scrofa)
        
        SOD3:Cu2+:Zn2+ [Golgi lumen] (Sus scrofa)
        
        Cu2+ [Golgi lumen]

External Reference Information

External Reference

copper(2+) [ChEBI:29036]

Participates

as an output of

ATP7B transports cytosolic Cu2+ to Golgi lumen (Canis familiaris)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Dictyostelium discoideum)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Danio rerio)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Gallus gallus)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Homo sapiens)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Mus musculus)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Rattus norvegicus)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Saccharomyces cerevisiae)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Schizosaccharomyces pombe)

as a component of

SOD3:Cu2+:Zn2+ [Golgi lumen] (Bos taurus)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Caenorhabditis elegans)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Canis familiaris)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Dictyostelium discoideum)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Drosophila melanogaster)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Danio rerio)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Gallus gallus)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Homo sapiens)
Sod3:Cu2+:Zn2+ [Golgi lumen] (Mus musculus)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Mus musculus)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Rattus norvegicus)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Saccharomyces cerevisiae)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Schizosaccharomyces pombe)
SOD3:Cu2+:Zn2+ [Golgi lumen] (Sus scrofa)

Other forms of this molecule

Cu2+ [mitochondrial intermembrane space]

Cu2+ [melanosome membrane]

Cu2+ [cytosol]

Cu2+ [extracellular region]

Cross References

COMPOUND

C00070

HMDB Metabolite

HMDB0000657

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