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I(1,3,4,6)P4 [cytosol]
Stable Identifier
R-ALL-994146
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
1D-myo-inositol 1,3,4,6-tetrakisphosphate, myo-inositol 1,3,4,6-tetrakisphosphate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Dictyostelium discoideum
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Factors involved in megakaryocyte development and platelet production (Bos taurus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)
I(1,3,4,6)P4 [cytosol]
Metabolism (Bos taurus)
Inositol phosphate metabolism (Bos taurus)
Synthesis of IP3 and IP4 in the cytosol (Bos taurus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,6)P4 [cytosol]
Programmed Cell Death (Bos taurus)
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
Regulation of necroptotic cell death (Bos taurus)
MLKL binds IP4, IP5 and IP6 (Bos taurus)
I(1,3,4,6)P4 [cytosol]
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Bos taurus)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
Hemostasis (Canis familiaris)
Factors involved in megakaryocyte development and platelet production (Canis familiaris)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Canis familiaris)
I(1,3,4,6)P4 [cytosol]
Metabolism (Canis familiaris)
Inositol phosphate metabolism (Canis familiaris)
Synthesis of IP3 and IP4 in the cytosol (Canis familiaris)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,6)P4 [cytosol]
Hemostasis (Danio rerio)
Factors involved in megakaryocyte development and platelet production (Danio rerio)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Danio rerio)
I(1,3,4,6)P4 [cytosol]
Metabolism (Danio rerio)
Inositol phosphate metabolism (Danio rerio)
Synthesis of IP3 and IP4 in the cytosol (Danio rerio)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,6)P4 [cytosol]
Hemostasis (Dictyostelium discoideum)
Factors involved in megakaryocyte development and platelet production (Dictyostelium discoideum)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Dictyostelium discoideum)
I(1,3,4,6)P4 [cytosol]
Metabolism (Dictyostelium discoideum)
Inositol phosphate metabolism (Dictyostelium discoideum)
Synthesis of IP3 and IP4 in the cytosol (Dictyostelium discoideum)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4,6)P4 [cytosol]
Hemostasis (Gallus gallus)
Factors involved in megakaryocyte development and platelet production (Gallus gallus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Gallus gallus)
I(1,3,4,6)P4 [cytosol]
Metabolism (Gallus gallus)
Inositol phosphate metabolism (Gallus gallus)
Synthesis of IP3 and IP4 in the cytosol (Gallus gallus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,6)P4 [cytosol]
Hemostasis (Homo sapiens)
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
IP3 and IP4 transport between cytosol and nucleus (Homo sapiens)
I(1,3,4,6)P4 transports from the cytosol to the nucleus (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
RIPK1-mediated regulated necrosis (Homo sapiens)
MLKL oligomerizes (Homo sapiens)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Homo sapiens)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
Regulation of necroptotic cell death (Homo sapiens)
MLKL binds IP4, IP5 and IP6 (Homo sapiens)
I(1,3,4,6)P4 [cytosol]
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Homo sapiens)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
Hemostasis (Mus musculus)
Factors involved in megakaryocyte development and platelet production (Mus musculus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Mus musculus)
I(1,3,4,6)P4 [cytosol]
Metabolism (Mus musculus)
Inositol phosphate metabolism (Mus musculus)
Synthesis of IP3 and IP4 in the cytosol (Mus musculus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,6)P4 [cytosol]
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
MLKL binds IP4, IP5 and IP6 (Mus musculus)
I(1,3,4,6)P4 [cytosol]
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Mus musculus)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
Hemostasis (Rattus norvegicus)
Factors involved in megakaryocyte development and platelet production (Rattus norvegicus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Rattus norvegicus)
I(1,3,4,6)P4 [cytosol]
Metabolism (Rattus norvegicus)
Inositol phosphate metabolism (Rattus norvegicus)
Synthesis of IP3 and IP4 in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,6)P4 [cytosol]
Programmed Cell Death (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
Regulation of necroptotic cell death (Rattus norvegicus)
MLKL binds IP4, IP5 and IP6 (Rattus norvegicus)
I(1,3,4,6)P4 [cytosol]
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Rattus norvegicus)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
Hemostasis (Sus scrofa)
Factors involved in megakaryocyte development and platelet production (Sus scrofa)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Sus scrofa)
I(1,3,4,6)P4 [cytosol]
Metabolism (Sus scrofa)
Inositol phosphate metabolism (Sus scrofa)
Synthesis of IP3 and IP4 in the cytosol (Sus scrofa)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,6)P4 [cytosol]
Programmed Cell Death (Sus scrofa)
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
Regulation of necroptotic cell death (Sus scrofa)
MLKL binds IP4, IP5 and IP6 (Sus scrofa)
I(1,3,4,6)P4 [cytosol]
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Sus scrofa)
IP4, IP5, IP6 [cytosol]
I(1,3,4,6)P4 [cytosol]
Hemostasis (Xenopus tropicalis)
Factors involved in megakaryocyte development and platelet production (Xenopus tropicalis)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Xenopus tropicalis)
I(1,3,4,6)P4 [cytosol]
Metabolism (Xenopus tropicalis)
Inositol phosphate metabolism (Xenopus tropicalis)
Synthesis of IP3 and IP4 in the cytosol (Xenopus tropicalis)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,6)P4 [cytosol]
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,6)P4 [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,6)P4 [cytosol]
External Reference Information
External Reference
myo-inositol 1,3,4,6-tetrakisphosphate(8-) [ChEBI:57660]
Participates
as an input of
MLKL binds IP4, IP5 and IP6 (Sus scrofa)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Dictyostelium discoideum)
MLKL binds IP4, IP5 and IP6 (Homo sapiens)
I(1,3,4,6)P4 transports from the cytosol to the nucleus (Homo sapiens)
MLKL binds IP4, IP5 and IP6 (Mus musculus)
MLKL binds IP4, IP5 and IP6 (Rattus norvegicus)
MLKL binds IP4, IP5 and IP6 (Bos taurus)
as an output of
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Dictyostelium discoideum)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Gallus gallus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Xenopus tropicalis)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Danio rerio)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Sus scrofa)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Canis familiaris)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Rattus norvegicus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Mus musculus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Homo sapiens)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
as a member of
IP4, IP5, IP6 [cytosol]
Other forms of this molecule
I(1,3,4,6)P4 [nucleoplasm]
Cross References
ZINC
000071789370
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