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lef [cytosol]
Stable Identifier
R-BAN-5211351
Type
Complex
Species
Bacillus anthracis
Compartment
cytosol
Synonyms
LF
GO Cellular Component
host cell cytosol
(0044164)
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of anthrax toxins (Homo sapiens)
Anthrax lef cleaves target cell MAP2K1 (MEK1) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
Anthrax lef cleaves target cell MAP2K2 (MEK2) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
Anthrax lef cleaves target cell MAP2K3 (MEK3) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
Anthrax lef cleaves target cell MAP2K4 (MEK4) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
Anthrax lef cleaves target cell MAP2K6 (MEK6) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
Anthrax lef cleaves target cell MAP2K7 (MEK7) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)
lef [cytosol] (Bacillus anthracis)
Literature References
PubMed ID
Title
Journal
Year
7854123
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
Klimpel, KR
,
Leppla, SH
,
Arora, N
Mol. Microbiol.
1994
Participants
components
lef [cytosol]
(Bacillus anthracis)
Zn2+ [cytosol]
Participates
as an output of
pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)
pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)
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