Reactome | p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm]

p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm]

Stable Identifier

R-BTA-111904

Type

Complex

Species

Bos taurus

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Neuronal System (Bos taurus)

- Transmission across Chemical Synapses (Bos taurus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
    - Activation of NMDA receptors and postsynaptic events (Bos taurus)
      - Post NMDA receptor activation events (Bos taurus)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Bos taurus)
        
        CAMK4 autophosphorylates (Bos taurus)
        
        p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)

Signal Transduction (Bos taurus)

- Intracellular signaling by second messengers (Bos taurus)
  - DAG and IP3 signaling (Bos taurus)
    - CaM pathway (Bos taurus)
      - Calmodulin induced events (Bos taurus)
        
        CaMK IV-mediated phosphorylation of CREB (Bos taurus)
        
        CAMK4 autophosphorylates (Bos taurus)
        
        p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Opioid Signalling (Bos taurus)
        
        G-protein mediated events (Bos taurus)
        
        PLC beta mediated events (Bos taurus)
        
        Ca-dependent events (Bos taurus)
        
        CaM pathway (Bos taurus)
        
        Calmodulin induced events (Bos taurus)
        
        CaMK IV-mediated phosphorylation of CREB (Bos taurus)
        
        CAMK4 autophosphorylates (Bos taurus)
        
        p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as an output of

CAMK4 autophosphorylates (Bos taurus)

Inferred From

p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Homo sapiens)

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