Reactome | BUB1B [cytosol]

BUB1B [cytosol]

Stable Identifier

R-BTA-141436

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

BUB1B, F1MWP1

Locations in the PathwayBrowser

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Cell Cycle (Bos taurus)

- Cell Cycle Checkpoints (Bos taurus)
  - Mitotic Spindle Checkpoint (Bos taurus)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Bos taurus)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Bos taurus)
        
        Formation of the MCC complex (Bos taurus)
        
        BUB1B [cytosol] (Bos taurus)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Bos taurus)
        
        BUB1B [cytosol] (Bos taurus)
- Cell Cycle, Mitotic (Bos taurus)
  - Regulation of mitotic cell cycle (Bos taurus)
    - APC/C-mediated degradation of cell cycle proteins (Bos taurus)
      - Regulation of APC/C activators between G1/S and early anaphase (Bos taurus)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Bos taurus)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Bos taurus)
        
        Formation of the MCC complex (Bos taurus)
        
        BUB1B [cytosol] (Bos taurus)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Bos taurus)
        
        BUB1B [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:F1MWP1

Gene Names

BUB1B

Reference Genes

BioGPS Gene:537027 BUB1B

ENSEMBL:ENSBTAG00000007237

KEGG Gene (Bos taurus):537027 BUB1B

Monarch:537027 BUB1B

NCBI Gene:537027 BUB1B

Reference Transcript

RefSeq:NM_001145173.1 BUB1B

Other Identifiers

537027

Bt.25661.1.A1_at

GO:0000003

GO:0000228

GO:0000278

GO:0000776

GO:0000778

GO:0000940

GO:0003674

GO:0004672

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0006464

GO:0006468

GO:0007049

GO:0007059

GO:0007091

GO:0007094

GO:0008150

GO:0016301

GO:0032991

GO:0043167

GO:0043226

GO:0051276

GO:0051754

GO:0071459

GO:0140014

Participates

as an input of

Formation of the MCC complex (Bos taurus)

as a component of

hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Bos taurus)

Inferred From

BUB1B [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001138645.1

OpenTargets

ENSG00000156970

Ensembl

ENSBTAP00000009521, ENSBTAT00000009521, ENSBTAG00000007237

VGNC

26605

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