Reactome | PABPC1 [cytosol]

PABPC1 [cytosol]

Stable Identifier

R-BTA-156803

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

PABPC1, P61286

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P61286

Gene Names

PABPC1

Reference Genes

BioGPS Gene:282296 PABPC1

ENSEMBL:ENSBTAG00000046358

ENSEMBL:ENSBTAG00000046358.2 PABPC1

KEGG Gene (Bos taurus):282296 PABPC1

Monarch:282296 PABPC1

NCBI Gene:282296 PABPC1

Reference Transcript

RefSeq:NM_174568.2 PABPC1

Other Identifiers

282296

GO:0003676

GO:0003723

Participates

as an input of

AUF1 binds translation and heat shock proteins (Bos taurus)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Bos taurus)

as a component of

AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Bos taurus)
mRNA Cleaved by SMG6 [cytosol] (Bos taurus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Bos taurus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Bos taurus)
Partially Deadenylated mRNA Complex [cytosol] (Bos taurus)
Translatable mRNA Complex [cytosol] (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)

as an output of

Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Bos taurus)
PARN deadenylates mRNA (Bos taurus)
CCR4-NOT complex deadenylates mRNA (Bos taurus)

Inferred From

PABPC1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_776993.1

OpenTargets

ENSG00000070756

Ensembl

ENSBTAT00000064237, ENSBTAP00000056644, ENSBTAG00000046358

VGNC

53870

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q28141	3	DHX9 [nucleoplasm] (R-BTA-53517) phospho-p-DHX9 [cytosol] (R-BTA-9836168) DHX9 [cytosol] (R-BTA-847700)	0.463	2