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phospho-p-T161-CDK1 [cytosol]
Stable Identifier
R-BTA-157415
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
P48734
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Initiation of Nuclear Envelope (NE) Reformation (Bos taurus)
CDK1 phosphorylates LBR (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Mitotic Prometaphase (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Mitotic Prophase (Bos taurus)
Nuclear Envelope Breakdown (Bos taurus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Bos taurus)
CDK1:CCNB phosphorylates NEK9 (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Nuclear Pore Complex (NPC) Disassembly (Bos taurus)
CDK1 phosphorylates NUP98 (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
Cyclin A/B1/B2 associated events during G2/M transition (Bos taurus)
Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Phosphorylation of Cyclin B1 in the CRS domain (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CRS kinase [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Bos taurus)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Bos taurus)
cytoplasmic Cyclin B1:Cdc2 complexes [cytosol] (Bos taurus)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
CDK1 phosphorylates BORA (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
Mitotic kinase [cytosol] (Bos taurus)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
APC/C:Cdc20 mediated degradation of Cyclin B (Bos taurus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Degradation of multiubiquitinated Cyclin B (Bos taurus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Bos taurus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Bos taurus)
Association of Cyclin A with the APC/C (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Degradation multiubiquitinated Cyclin A (Bos taurus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF-independent MAPK1/3 activation (Bos taurus)
MAPK3 (ERK1) activation (Bos taurus)
Inactivation of MAP2K1 by CDK1 (Bos taurus)
phospho-p-T161-CDK1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:P48734
Reference Genes
BioGPS Gene:281061
ENSEMBL:ENSBTAG00000010109
ENSEMBL:ENSBTAG00000010109.4
KEGG Gene (Bos taurus):281061
Monarch:281061
NCBI Gene:281061
Reference Transcript
RefSeq:XM_005226297.3
RefSeq:NM_174016.2
RefSeq:XM_005226299.2
Other Identifiers
281061
Participates
as an output of
Degradation of multiubiquitinated Cyclin B (Bos taurus)
Degradation multiubiquitinated Cyclin A (Bos taurus)
as a component of
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Bos taurus)
CCNB2:p-T161-CDK1 [cytosol] (Bos taurus)
CCNB1:p-T161-CDK1 [cytosol] (Bos taurus)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Bos taurus)
Other forms of this molecule
CDK1 [endoplasmic reticulum membrane]
phospho-p-Y4-CDK1 [cytosol]
phospho-p-T14,T161-CDK1 [nucleoplasm]
phospho-p-T14-CDK1 [nucleoplasm]
phospho-p-T14-CDK1 [cytosol]
CDK1 [nucleoplasm]
CDK1 [cytosol]
phospho-p-T14,Y15,T161-CDK1 [cytosol]
phospho-p-T14,Y15,T161-CDK1 [nucleoplasm]
phospho-p-T161-CDK1 [nucleoplasm]
Inferred From
p-T161-CDK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 161 (in Homo sapiens)
Coordinate
161
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_005226354.1
,
XP_005226356.1
,
NP_776441.1
IntEnz
2.7.11.23
Ensembl
ENSBTAP00000013337
,
ENSBTAT00000013337
,
ENSBTAG00000010109
VGNC
27115
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