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CDK1 [cytosol]
Stable Identifier
R-BTA-170075
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
P48734
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G2/M Checkpoints (Bos taurus)
G2/M DNA replication checkpoint (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
CCNB:CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prometaphase (Bos taurus)
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Translocation of NuMA to the centrosomes (Bos taurus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
AURKA Activation by TPX2 (Bos taurus)
TPX2 binds AURKA at centrosomes (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
TPX2 promotes AURKA autophosphorylation (Bos taurus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome maturation (Bos taurus)
Loss of proteins required for interphase microtubule organization from the centrosome (Bos taurus)
Loss of C-Nap-1 from centrosomes (Bos taurus)
cNAP-1 depleted centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Loss of Nlp from mitotic centrosomes (Bos taurus)
Dissociation of Phospho-Nlp from the centrosome (Bos taurus)
Nlp-depleted centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome containing phosphorylated Nlp [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Plk1-mediated phosphorylation of Nlp (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome containing phosphorylated Nlp [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Recruitment of mitotic centrosome proteins and complexes (Bos taurus)
Recruitment of CDK11p58 to the centrosomes (Bos taurus)
Centrosomes containing recruited CDK11p58 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Recruitment of Plk1 to centrosomes (Bos taurus)
Centrosome associated Plk1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Cyclin A/B1/B2 associated events during G2/M transition (Bos taurus)
Formation of Cyclin A:Cdc2 complexes (Bos taurus)
CCNA:CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Formation of Cyclin B:Cdc2 complexes (Bos taurus)
CCNB:CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
CCNB:CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
AJUBA binds centrosome-associated AURKA (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:AURKA:AJUBA [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
AJUBA facilitates AURKA autophosphorylation (Bos taurus)
Centrosome:AURKA:AJUBA [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
AURKA phosphorylates PLK1 (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
BORA binds PLK1 and AURKA (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Transcription of Cell Cycle Genes (Bos taurus)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Bos taurus)
SFN dimer binds CDK1 and CCNB1 (Bos taurus)
CCNB1:CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
SFN Dimer:CCNB1:CDK1 [cytosol] (Bos taurus)
CCNB1:CDK1 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
PKR-mediated signaling (Bos taurus)
p-PKR dimer phosphorylates CDK1 (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
Anchoring of the basal body to the plasma membrane (Bos taurus)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
C2CD3 binds the mother centriole (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
CP110 and CEP97 dissociate from the centriole (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
MARK4 binds ODF2 in the centriole (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Recruitment of transition zone proteins (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
The distal appendage proteins recruit TTBK2 (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
CDK1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:P48734
Reference Genes
BioGPS Gene:281061
ENSEMBL:ENSBTAG00000010109
ENSEMBL:ENSBTAG00000010109.4
KEGG Gene (Bos taurus):281061
Monarch:281061
NCBI Gene:281061
Reference Transcript
RefSeq:XM_005226297.3
RefSeq:NM_174016.2
RefSeq:XM_005226299.2
Other Identifiers
281061
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
Nlp-depleted centrosome [cytosol] (Bos taurus)
centrosome containing phosphorylated Nlp [cytosol] (Bos taurus)
cNAP-1 depleted centrosome [cytosol] (Bos taurus)
CCNB1:CDK1 [cytosol] (Bos taurus)
CCNA:CDK1 [cytosol] (Bos taurus)
CCNB:CDK1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
as an input of
p-PKR dimer phosphorylates CDK1 (Bos taurus)
Formation of Cyclin A:Cdc2 complexes (Bos taurus)
Formation of Cyclin B:Cdc2 complexes (Bos taurus)
Other forms of this molecule
CDK1 [endoplasmic reticulum membrane]
phospho-p-Y4-CDK1 [cytosol]
phospho-p-T14,T161-CDK1 [nucleoplasm]
phospho-p-T14-CDK1 [nucleoplasm]
phospho-p-T14-CDK1 [cytosol]
CDK1 [nucleoplasm]
phospho-p-T14,Y15,T161-CDK1 [cytosol]
phospho-p-T161-CDK1 [cytosol]
phospho-p-T14,Y15,T161-CDK1 [nucleoplasm]
phospho-p-T161-CDK1 [nucleoplasm]
Inferred From
CDK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005226354.1
,
XP_005226356.1
,
NP_776441.1
IntEnz
2.7.11.23
Ensembl
ENSBTAP00000013337
,
ENSBTAT00000013337
,
ENSBTAG00000010109
VGNC
27115
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