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p-2S-SMAD2,3 [cytosol]
Stable Identifier
R-BTA-171182
Type
Set [DefinedSet]
Species
Bos taurus
Compartment
cytosol
Synonyms
p-S465,467-SMAD2,p-S423,425-SMAD3, Phospho-R-SMAD
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Signaling by NODAL (Bos taurus)
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Bos taurus)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Bos taurus)
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by TGFB family members (Bos taurus)
Signaling by Activin (Bos taurus)
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Signaling by TGF-beta Receptor Complex (Bos taurus)
TGF-beta receptor signaling activates SMADs (Bos taurus)
Activated type I receptor phosphorylates SMAD2/3 directly (Bos taurus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Downregulation of TGF-beta receptor signaling (Bos taurus)
MTMR4 binds phosphorylated SMAD2/3 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
p-2S-SMAD2/3:MTMR4 [early endosome membrane] (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
MTMR4 dephosphorylates SMAD2/3 (Bos taurus)
p-2S-SMAD2/3:MTMR4 [early endosome membrane] (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
PMEPA1 sequesters phosphorylated SMAD2/3 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
p-2S-SMAD2/3:PMEPA1 [early endosome membrane] (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Phosphorylated SMAD2/3 dissociates from TGFBR (Bos taurus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Bos taurus)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Bos taurus)
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Bos taurus)
p-2S-SMAD2,3 [cytosol] (Bos taurus)
Participants
members
phospho-SMAD2 [cytosol]
(Bos taurus)
phospho-SMAD3 [cytosol]
(Bos taurus)
Participates
as an input of
PMEPA1 sequesters phosphorylated SMAD2/3 (Bos taurus)
MTMR4 binds phosphorylated SMAD2/3 (Bos taurus)
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Bos taurus)
as a component of
p-2S-SMAD2/3:PMEPA1 [early endosome membrane] (Bos taurus)
p-2S-SMAD2/3:MTMR4 [early endosome membrane] (Bos taurus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Bos taurus)
as an output of
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Bos taurus)
Phosphorylated SMAD2/3 dissociates from TGFBR (Bos taurus)
Inferred From
p-2S-SMAD2,3 [cytosol]
(Homo sapiens)
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