Reactome | Cdh1:phospho-APC/C complex [nucleoplasm]

Cdh1:phospho-APC/C complex [nucleoplasm]

Stable Identifier

R-BTA-174250

Type

Complex

Species

Bos taurus

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

FZR1 [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)

Participates

as a component of

Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)

as an input of

Cdh1:APC/C complex binds EHMT1:EHMT2 (Bos taurus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)
Association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)

as an output of

APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)

Inferred From

Cdh1:phospho-APC/C complex [nucleoplasm] (Homo sapiens)

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