Reactome | PSMC5 [nucleoplasm]

PSMC5 [nucleoplasm]

Stable Identifier

R-BTA-174312

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

P62194

Locations in the PathwayBrowser

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Cellular responses to stimuli (Bos taurus)

- Cellular responses to stress (Bos taurus)
  - Cellular response to chemical stress (Bos taurus)
    - KEAP1-NFE2L2 pathway (Bos taurus)
      - Nuclear events mediated by NFE2L2 (Bos taurus)
        
        GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Bos taurus)
        
        Ub,pS335,S338,T NFE2L2 is degraded (Bos taurus)
        
        26S proteasome [nucleoplasm] (Bos taurus)
        
        PSMC5 [nucleoplasm] (Bos taurus)

Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Deubiquitination (Bos taurus)
    - Ub-specific processing proteases (Bos taurus)
      - USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Bos taurus)
        
        USP37:RUVLB1:PSMC5:CCNA1,CCNA2 [nucleoplasm] (Bos taurus)
        
        USP37:RUVLB1:PSMC5 [nucleoplasm] (Bos taurus)
        
        PSMC5 [nucleoplasm] (Bos taurus)
        
        USP37:RUVLB1:PSMC5:PolyUb-CCNA1,PolyUb-CCNA2 [nucleoplasm] (Bos taurus)
        
        USP37:RUVLB1:PSMC5 [nucleoplasm] (Bos taurus)
        
        PSMC5 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:P62194

Reference Genes

BioGPS Gene:282015

ENSEMBL:ENSBTAG00000021061

KEGG Gene (Bos taurus):282015

Monarch:282015

NCBI Gene:282015

Reference Transcript

RefSeq:NM_174441.2

Other Identifiers

282015

Bt.8062.1.S1_at

GO:0000502

GO:0003824

GO:0005102

GO:0005524

GO:0005634

GO:0005737

GO:0005838

GO:0006351

GO:0006355

GO:0006357

GO:0016787

GO:0016887

GO:0022624

GO:0030163

GO:0031410

GO:0031531

GO:0036402

GO:0043161

GO:0043226

GO:0045892

GO:0140296

GO:0140297

GO:0140657

Participates

as a component of

Other forms of this molecule

PSMC5 [cytosol]

Inferred From

PSMC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_776866.1

Ensembl

ENSBTAT00000028048, ENSBTAG00000021061, ENSBTAP00000028048

VGNC

33459