Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Microtubule [cytosol]
Stable Identifier
R-BTA-190599
Type
Complex
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Selective autophagy (Bos taurus)
Aggrephagy (Bos taurus)
Aggresome dissociates from dynein and microtubule (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 binds to microtubules (Bos taurus)
EML4 homotrimer:Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Kinetochore capture of astral microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Hemostasis (Bos taurus)
Factors involved in megakaryocyte development and platelet production (Bos taurus)
Kinesins (Bos taurus)
Kinesins bind microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
MHC class II antigen presentation (Bos taurus)
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
TTLLs polyglutamylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
ATAT acetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
HDAC6 deacetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RHO GTPases activate IQGAPs (Bos taurus)
IQGAP1 binds CLIP1 and microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Gap junction trafficking and regulation (Bos taurus)
Gap junction trafficking (Bos taurus)
Gap junction assembly (Bos taurus)
Transport of connexons to the plasma membrane (Bos taurus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Bos taurus)
Association of Golgi transport vesicles with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-dependent Golgi-to-ER retrograde traffic (Bos taurus)
Retrograde COPI vesicles bind kinesin and microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Bos taurus)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 13
Microtubule protofilament [cytosol]
(Bos taurus)
Participates
as an output of
HDAC6 deacetylates microtubules (Bos taurus)
Aggresome dissociates from dynein and microtubule (Bos taurus)
as an input of
ATAT acetylates microtubules (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
TTLLs polyglutamylate tubulin (Bos taurus)
Kinesins bind microtubules (Bos taurus)
IQGAP1 binds CLIP1 and microtubules (Bos taurus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
EML4 binds to microtubules (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Kinetochore capture of astral microtubules (Bos taurus)
Association of Golgi transport vesicles with microtubules (Bos taurus)
as a component of
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
AP2 clathrin:L1:KIF4:microtubule [cytosol] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
EML4 homotrimer:Microtubule [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Inferred From
microtubule (no TUBA4B) [cytosol]
(Homo sapiens)
Microtubule [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
