Reactome | SRGAP2 [cytosol]

SRGAP2 [cytosol]

Stable Identifier

R-BTA-195131

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

SRGAP2, A0A3Q1LMM5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A0A3Q1LMM5

Gene Names

SRGAP2

Reference Genes

BioGPS Gene:519843 SRGAP2

ENSEMBL:ENSBTAG00000001483.5

KEGG Gene (Bos taurus):519843 SRGAP2

Monarch:519843 SRGAP2

NCBI Gene:519843 SRGAP2

Reference Transcript

Other Identifiers

519843

GO:0005096

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0007010

GO:0007165

GO:0014069

GO:0021816

GO:0023052

GO:0030154

GO:0030334

GO:0030336

GO:0031267

GO:0031410

GO:0034330

GO:0042803

GO:0043197

GO:0043226

GO:0045211

GO:0045335

GO:0046847

GO:0048812

GO:0048856

GO:0048870

GO:0060996

GO:0098772

GO:1904861

GO:1904862

Participates

as a candidate of

as a member of

RAC1 GAPs [cytosol] (Bos taurus)

as an output of

SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)

as an input of

SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Bos taurus)

as a component of

SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)

Inferred From

SRGAP2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005216735.1, NP_001192794.1

OpenTargets

ENSG00000266028

Ensembl

ENSBTAT00000068363, ENSBTAP00000058133, ENSBTAG00000001483