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SRGAP2 [cytosol]
Stable Identifier
R-BTA-195131
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
SRGAP2, A0A3Q1LMM5
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RHO GTPase cycle (Bos taurus)
CDC42 GTPase cycle (Bos taurus)
CDC42 GAPs stimulate CDC42 GTPase activity (Bos taurus)
CDC42 GAPs [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RAC1 GTPase cycle (Bos taurus)
RAC1 GAPs stimulate RAC1 GTPase activity (Bos taurus)
RAC1 GAPs [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RAC3 GTPase cycle (Bos taurus)
RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)
RAC3 GAPs [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RHOF GTPase cycle (Bos taurus)
RHOF GAPs stimulate RHOF GTPase activity (Bos taurus)
RHOF GAPs [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RHOQ GTPase cycle (Bos taurus)
RHOQ GAPs stimulate RHOQ GTPase activity (Bos taurus)
RHOQ GAPs [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RHOU GTPase cycle (Bos taurus)
RHOU binds effectors at the plasma membrane (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
RHOU:GTP:RHOU effectors [plasma membrane] (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
SRGAP2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1LMM5
Gene Names
SRGAP2
Reference Genes
BioGPS Gene:519843 SRGAP2
ENSEMBL:ENSBTAG00000001483.5
ENSEMBL:ENSBTAG00000001483.6 SRGAP2
KEGG Gene (Bos taurus):519843 SRGAP2
Monarch:519843 SRGAP2
NCBI Gene:519843 SRGAP2
Reference Transcript
RefSeq:XM_005216678.3 SRGAP2
RefSeq:NM_001205865.1 SRGAP2
Other Identifiers
519843
GO:0005096
GO:0005829
GO:0005886
GO:0007010
GO:0014069
GO:0021816
GO:0030154
GO:0030334
GO:0031267
GO:0031410
GO:0034330
GO:0042803
GO:0043197
GO:0043226
GO:0045211
GO:0045335
GO:0046847
GO:0048812
GO:0048856
GO:0048870
GO:0060996
GO:0098772
GO:1904861
GO:1904862
Participates
as a candidate of
RHOQ GAPs [cytosol] (Bos taurus)
CDC42 GAPs [cytosol] (Bos taurus)
RHOF GAPs [cytosol] (Bos taurus)
RAC3 GAPs [cytosol] (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
as a member of
RAC1 GAPs [cytosol] (Bos taurus)
as an output of
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)
as an input of
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Bos taurus)
as a component of
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
Inferred From
SRGAP2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001192794.1
,
XP_005216735.1
OpenTargets
ENSG00000266028
Ensembl
ENSBTAP00000058133
,
ENSBTAG00000001483
,
ENSBTAT00000068363
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