Reactome | BTRC:CUL1:RBX1:SKP1 [cytosol]

BTRC:CUL1:RBX1:SKP1 [cytosol]

Stable Identifier

R-BTA-206748

Type

Complex

Species

Bos taurus

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

CUL1 [cytosol] (Bos taurus)
Ghost homologue of BTRC [cytosol] (Bos taurus)
LOC780968 [cytosol] (Bos taurus)
SKP1 [cytosol] (Bos taurus)

Participates

as an output of

Degradation of ubiquitinated beta catenin by the proteasome (Bos taurus)

as an input of

Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Bos taurus)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Bos taurus)

as a component of

RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Bos taurus)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Bos taurus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Bos taurus)

Inferred From

BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)