Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-T210-PLK1 [cytosol]
Stable Identifier
R-BTA-3000318
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
Q2TA25
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
PLK1 phosphorylates NUDC (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
FIRRM binds PLK1 (Bos taurus)
FIRRM:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
PLK1 phosphorylates FIRMM at S744 (Bos taurus)
p-S43-FIRRM:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
PLK1 phosphorylates FIRRM at S43 (Bos taurus)
FIRRM:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
p-S43-FIRRM:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
PPP1CC dephosphorylates PLK1 (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Mitotic Prophase (Bos taurus)
Golgi Cisternae Pericentriolar Stack Reorganization (Bos taurus)
PLK1 phosphorylates GORASP1 (Bos taurus)
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Nuclear Envelope Breakdown (Bos taurus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Bos taurus)
PLK1 phosphorylates NEK9 (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
Centrosome maturation (Bos taurus)
Loss of proteins required for interphase microtubule organization from the centrosome (Bos taurus)
Loss of Nlp from mitotic centrosomes (Bos taurus)
Plk1-mediated phosphorylation of Nlp (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Polo-like kinase mediated events (Bos taurus)
Activation of Cdc25C (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
AURKA phosphorylates PLK1 (Bos taurus)
p-S252-BORA:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
Cytosolic PLK1 translocates to the nucleus (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
PLK1 phosphorylates BORA (Bos taurus)
p-S252-BORA:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
PLK1 phosphorylates OPTN (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds PLK1 (Bos taurus)
GTSE1:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
PLK1 phosphorylates GTSE1 (Bos taurus)
GTSE1:p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
phospho-p-T210-PLK1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q2TA25
Reference Genes
BioGPS Gene:538238
ENSEMBL:ENSBTAG00000014453
KEGG:bta:538238
Monarch:538238
NCBI Gene:538238
UCSC:Q2TA25
Reference Transcript
RefSeq:NM_001038173.2
Other Identifiers
538238
GO:0000070
GO:0000086
GO:0000122
GO:0000132
GO:0000278
GO:0000281
GO:0000287
GO:0000775
GO:0000776
GO:0000779
GO:0000785
GO:0000795
GO:0000910
GO:0000922
GO:0000940
GO:0001578
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005813
GO:0005814
GO:0005815
GO:0005819
GO:0005856
GO:0005876
GO:0006281
GO:0006302
GO:0006355
GO:0007010
GO:0007059
GO:0007094
GO:0007095
GO:0007098
GO:0007346
GO:0008017
GO:0008092
GO:0010800
GO:0010997
GO:0015630
GO:0016321
GO:0016567
GO:0016740
GO:0019901
GO:0022414
GO:0030071
GO:0030496
GO:0031648
GO:0032436
GO:0032465
GO:0033365
GO:0034451
GO:0042802
GO:0043066
GO:0043226
GO:0045143
GO:0045184
GO:0045862
GO:0051081
GO:0051233
GO:0061024
GO:0070194
GO:0071168
GO:0090435
GO:0097431
GO:0097681
GO:0106310
GO:0140096
GO:1901673
GO:1904776
GO:2000042
Participates
as a component of
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
FIRRM:p-T210-PLK1 [cytosol] (Bos taurus)
p-S43-FIRRM:p-T210-PLK1 [cytosol] (Bos taurus)
GTSE1:p-T210-PLK1 [cytosol] (Bos taurus)
p-S252-BORA:p-T210-PLK1 [cytosol] (Bos taurus)
as an input of
PPP1CC dephosphorylates PLK1 (Bos taurus)
FIRRM binds PLK1 (Bos taurus)
Cytosolic PLK1 translocates to the nucleus (Bos taurus)
GTSE1 binds PLK1 (Bos taurus)
as an output of
PLK1 phosphorylates FIRMM at S744 (Bos taurus)
PLK1 phosphorylates BORA (Bos taurus)
PLK1 phosphorylates GTSE1 (Bos taurus)
Other forms of this molecule
PLK1 [nucleoplasm]
phospho-p-T210-PLK1 [nucleoplasm]
PLK1 [cytosol]
Inferred From
p-T210-PLK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 210 (in Homo sapiens)
Coordinate
210
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001033262.1
ENSEMBL
ENSBTAT00000019217
,
ENSBTAP00000019217
IntEnz
2.7.11.21
VGNC
33033
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text