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RPTOR [cytosol]
Stable Identifier
R-BTA-3006727
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
RPTOR, F1MG06
Locations in the PathwayBrowser
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Active MTORC1 binds the ULK1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Active MTORC1 phosphorylates ULK1 (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B hydrolyzes GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1 binds RHEB:GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
MAF1 translocates to the nucleus (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1 phosphorylates MAF1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
MTOR signalling (Bos taurus)
AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Formation of active mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1-mediated signalling (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
mTORC1 [cytosol] (Bos taurus)
RPTOR [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MG06
Gene Names
RPTOR
Reference Genes
ENSEMBL:ENSBTAG00000002883.6
ENSEMBL:ENSBTAG00000002883.7 RPTOR
Other Identifiers
GO:0000278
GO:0001558
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0006351
GO:0006355
GO:0006914
GO:0008361
GO:0009267
GO:0010494
GO:0010506
GO:0010507
GO:0010800
GO:0019901
GO:0023052
GO:0030291
GO:0030295
GO:0030307
GO:0030674
GO:0031267
GO:0031669
GO:0031929
GO:0031931
GO:0032008
GO:0033138
GO:0036211
GO:0038202
GO:0043226
GO:0044877
GO:0045945
GO:0060090
GO:0071230
GO:0071233
GO:0071333
GO:0071889
GO:0098772
GO:0140767
GO:1900087
Participates
as a component of
mTORC1 [cytosol] (Bos taurus)
Other forms of this molecule
RPTOR [nucleoplasm]
phospho-RPTOR [cytosol]
Inferred From
RPTOR [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000141564
Ensembl
ENSBTAP00000003739
,
ENSBTAG00000002883
,
ENSBTAT00000003739
VGNC
34153
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