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NR1H3 [nucleoplasm]
Stable Identifier
R-BTA-3008623
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
NR1H3-1, Q5E9B6
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Nuclear Receptor transcription pathway (Bos taurus)
Formation of NR-MED1 Coactivator Complex (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR-MED1 Coactivator Complex [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
Formation of NR-NCOR Corepressor Complex (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR-NCOR CoRepressor Complex [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
SUMOylation (Bos taurus)
SUMO E3 ligases SUMOylate target proteins (Bos taurus)
SUMOylation of intracellular receptors (Bos taurus)
HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Bos taurus)
NR1H3:hydroxycholesterol [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
NR1H2 and NR1H3-mediated signaling (Bos taurus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Bos taurus)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NCOR [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Bos taurus)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NCOA1 recruits EP300 to the ABCA1 promoter (Bos taurus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Bos taurus)
NR1H2,3:RXR [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
Transport of small molecules (Bos taurus)
Plasma lipoprotein assembly, remodeling, and clearance (Bos taurus)
Plasma lipoprotein clearance (Bos taurus)
VLDLR internalisation and degradation (Bos taurus)
MYLIP dimer ubiquitinates VLDLR on Lys-839 (Bos taurus)
NR1H2,NR1H3 [nucleoplasm] (Bos taurus)
NR1H3 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:Q5E9B6
Gene Names
NR1H3
Reference Genes
BioGPS Gene:507176 NR1H3
ENSEMBL:ENSBTAG00000010681
ENSEMBL:ENSBTAG00000010681.5 NR1H3
KEGG Gene (Bos taurus):507176 NR1H3
Monarch:507176 NR1H3
NCBI Gene:507176 NR1H3
Reference Transcript
RefSeq:NM_001014861.1 NR1H3
Other Identifiers
507176
GO:0000122
GO:0000785
GO:0000976
GO:0000978
GO:0001228
GO:0002376
GO:0003677
GO:0003700
GO:0004879
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006629
GO:0006954
GO:0009755
GO:0010867
GO:0010875
GO:0010887
GO:0016071
GO:0016192
GO:0022600
GO:0023052
GO:0031490
GO:0032369
GO:0032376
GO:0032570
GO:0032810
GO:0034145
GO:0036151
GO:0042632
GO:0042789
GO:0043031
GO:0043226
GO:0043235
GO:0043277
GO:0044255
GO:0045723
GO:0045861
GO:0045892
GO:0045893
GO:0045944
GO:0046889
GO:0048550
GO:0050728
GO:0051247
GO:0055088
GO:0055092
GO:0060089
GO:0070328
GO:0071222
GO:0090188
GO:0090341
GO:0090575
GO:0098542
GO:0120163
GO:0140110
GO:1903573
Participates
as a component of
NR1H3:hydroxycholesterol [nucleoplasm] (Bos taurus)
NR1H3:RXRB [nucleoplasm] (Bos taurus)
NR1H3:RXRA [nucleoplasm] (Bos taurus)
as a member of
NR1H2,NR1H3 [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
Other forms of this molecule
NR1H3 [nucleoplasm]
Inferred From
NR1H3 [nucleoplasm]
(Homo sapiens)
NR1H3-1 [nucleoplasm]
(Homo sapiens)
NR1H3-2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001014861.1
OpenTargets
ENSG00000025434
Ensembl
ENSBTAT00000071739
,
ENSBTAP00000060937
,
ENSBTAG00000010681
,
ENSBTAP00000014131
,
ENSBTAT00000014131
VGNC
32231
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