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TP53 Tetramer [nucleoplasm]
Stable Identifier
R-BTA-3209194
Type
Complex
Species
Bos taurus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G1/S DNA Damage Checkpoints (Bos taurus)
p53-Dependent G1/S DNA damage checkpoint (Bos taurus)
p53-Dependent G1 DNA Damage Response (Bos taurus)
Stabilization of p53 (Bos taurus)
ATM phosphorylates TP53 at S15 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
G2/M Checkpoints (Bos taurus)
G2/M DNA damage checkpoint (Bos taurus)
ATR phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
DNA Damage/Telomere Stress Induced Senescence (Bos taurus)
ATM phosphorylates TP53 at S15 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Oxidative Stress Induced Senescence (Bos taurus)
MAPKAPK5 phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
DNA Repair (Bos taurus)
DNA Double-Strand Break Repair (Bos taurus)
DNA Double Strand Break Response (Bos taurus)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Bos taurus)
ATM phosphorylates TP53 at S15 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
Regulation of TP53 Activity (Bos taurus)
Regulation of TP53 Activity through Association with Co-factors (Bos taurus)
BANP binds TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53:BANP [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Regulation of TP53 Activity through Methylation (Bos taurus)
EHMT1:EHMT2 dimethylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Regulation of TP53 Activity through Phosphorylation (Bos taurus)
AMPK phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
ATM phosphorylates TP53 at S15 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
ATR phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
AURKA phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
CDK2 phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
CDK5 phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
MAPKAPK5 phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
NUAK1 phosphorylates TP53 (Bos taurus)
TP53 Tetramer:STK11:p-T211-NUAK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
STK11 (LKB1) phosphorylates NUAK1 (Bos taurus)
TP53 Tetramer:STK11:NUAK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53 Tetramer:STK11:p-T211-NUAK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TAF1 phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53 binds HIPK1 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53 Tetramer:HIPK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53 binds STK11 and NUAK1 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53 Tetramer:STK11:NUAK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53RK phosphorylates TP53 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Regulation of TP53 Expression and Degradation (Bos taurus)
Regulation of TP53 Degradation (Bos taurus)
USP7 deubiquitinates TP53 and counteracts MDM2 (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Regulation of TP53 Expression (Bos taurus)
TP53 forms homotetramers (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Transcriptional regulation by RUNX3 (Bos taurus)
RUNX3 regulates CDKN1A transcription (Bos taurus)
RUNX3 binds TP53 (Bos taurus)
RUNX3:TP53 tetramer [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
PKR-mediated signaling (Bos taurus)
p-PKR dimer phosphorylates TP53 tetramer (Bos taurus)
TP53 Tetramer [nucleoplasm] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 4
TP53 [nucleoplasm]
(Bos taurus)
Participates
as an input of
RUNX3 binds TP53 (Bos taurus)
p-PKR dimer phosphorylates TP53 tetramer (Bos taurus)
BANP binds TP53 (Bos taurus)
EHMT1:EHMT2 dimethylates TP53 (Bos taurus)
AURKA phosphorylates TP53 (Bos taurus)
TP53 binds HIPK1 (Bos taurus)
CDK2 phosphorylates TP53 (Bos taurus)
CDK5 phosphorylates TP53 (Bos taurus)
TAF1 phosphorylates TP53 (Bos taurus)
TP53 binds STK11 and NUAK1 (Bos taurus)
MAPKAPK5 phosphorylates TP53 (Bos taurus)
AMPK phosphorylates TP53 (Bos taurus)
TP53RK phosphorylates TP53 (Bos taurus)
ATM phosphorylates TP53 at S15 (Bos taurus)
ATR phosphorylates TP53 (Bos taurus)
as a component of
RUNX3:TP53 tetramer [nucleoplasm] (Bos taurus)
TP53:BANP [nucleoplasm] (Bos taurus)
TP53 Tetramer:HIPK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer:STK11:p-T211-NUAK1 [nucleoplasm] (Bos taurus)
TP53 Tetramer:STK11:NUAK1 [nucleoplasm] (Bos taurus)
as an output of
USP7 deubiquitinates TP53 and counteracts MDM2 (Bos taurus)
TP53 forms homotetramers (Bos taurus)
Inferred From
TP53 Tetramer [nucleoplasm]
(Homo sapiens)
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