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phospho-p-6Y-PTK2 [cytosol]
Stable Identifier
R-BTA-354128
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
A0A3Q1N508
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Bos taurus)
pFAK:Grb2:Sos [cytosol] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Recruitment of Grb2 to pFAK:NCAM1 (Bos taurus)
Grb2:pFAK bound to NCAM1:pFyn [plasma membrane] (Bos taurus)
pFAK:Grb2 [cytosol] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Multiple phosphorylated FAK bound to NCAM:pFyn [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
SOS binds Grb2 bound to pFAK:NCAM1 (Bos taurus)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Bos taurus)
pFAK:Grb2:Sos [cytosol] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Grb2:pFAK bound to NCAM1:pFyn [plasma membrane] (Bos taurus)
pFAK:Grb2 [cytosol] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
FAK-SRC complex [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Integrin signaling (Bos taurus)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
FAK-SRC complex [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Bos taurus)
pFAK:Grb2:Sos [cytosol] (Bos taurus)
phospho-p-6Y-PTK2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1N508
Reference Genes
ENSEMBL:ENSBTAG00000009578.6
ENSEMBL:ENSBTAG00000009578.7
Other Identifiers
GO:0000166
GO:0001525
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005524
GO:0005856
GO:0005886
GO:0005925
GO:0005938
GO:0007155
GO:0007172
GO:0007173
GO:0008284
GO:0016020
GO:0016740
GO:0023052
GO:0030054
GO:0030155
GO:0030335
GO:0036211
GO:0042995
GO:0043197
GO:0043226
GO:0048856
GO:0048870
GO:0050896
GO:0051128
GO:0051239
GO:0065003
GO:0065008
GO:0070161
GO:0140096
Participates
as a component of
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
FAK-SRC complex [plasma membrane] (Bos taurus)
Multiple phosphorylated FAK bound to NCAM:pFyn [plasma membrane] (Bos taurus)
pFAK:Grb2 [cytosol] (Bos taurus)
pFAK:Grb2:Sos [cytosol] (Bos taurus)
Other forms of this molecule
phospho-p-5Y-PTK2 [cytosol]
phospho-p-5Y,S732-PTK2 [cytosol]
phospho-p-6Y,S732-PTK2 [cytosol]
phospho-pY-PTK2 [cytosol]
phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
phospho-p-Y194,Y397-PTK2 [cytosol]
PTK2(773-1052) [cytosol]
PTK2(1-772) [cytosol]
PTK2 [cytosol]
phospho-p-Y397-PTK2 [cytosol]
Inferred From
p-6Y-PTK2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 397 (in Homo sapiens)
Coordinate
397
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 576 (in Homo sapiens)
Coordinate
576
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 577 (in Homo sapiens)
Coordinate
577
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 861 (in Homo sapiens)
Coordinate
861
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 925 (in Homo sapiens)
Coordinate
925
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 407 (in Homo sapiens)
Coordinate
407
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
Ensembl
ENSBTAG00000009578
,
ENSBTAP00000065036
,
ENSBTAT00000085237
VGNC
33518
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