Reactome | SDCCAG8 [cytosol]

SDCCAG8 [cytosol]

Stable Identifier

R-BTA-380273

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

SDCCAG8, E1BKZ3

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Bos taurus)

- Cilium Assembly (Bos taurus)
  - Anchoring of the basal body to the plasma membrane (Bos taurus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Bos taurus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - C2CD3 binds the mother centriole (Bos taurus)
      - mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)
      - basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
        
        basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - CP110 and CEP97 dissociate from the centriole (Bos taurus)
      - basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - MARK4 binds ODF2 in the centriole (Bos taurus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
        
        basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - Recruitment of transition zone proteins (Bos taurus)
      - basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
    - The distal appendage proteins recruit TTBK2 (Bos taurus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        SDCCAG8 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BKZ3

Gene Names

SDCCAG8

Reference Genes

ENSEMBL:ENSBTAG00000017775.6

Other Identifiers

616342

GO:0001764

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0007010

GO:0007098

GO:0007163

GO:0030010

GO:0030154

GO:0031023

GO:0035148

GO:0043226

GO:0048856

GO:0048870

Participates

as a component of

Inferred From

SDCCAG8 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000054282

Ensembl

ENSBTAG00000017775, ENSBTAT00000023634, ENSBTAP00000023634

VGNC

96545

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