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NEDD8 [cytosol]
Stable Identifier
R-BTA-416969
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
NEDD8, P61282
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Deubiquitination (Bos taurus)
UCH proteinases (Bos taurus)
UCHL3, SENP8 cleave NEDD8 (Bos taurus)
UCHL3,SENP8:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Neddylation (Bos taurus)
26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Bos taurus)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Bos taurus)
NEDD8,UBD [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Bos taurus)
AcM-UBE2F:NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Bos taurus)
AcM-UBE2M:NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8 and UBD bind NUB1 and the 26S proteasome (Bos taurus)
NEDD8,UBD [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Bos taurus)
NEDD8,UBD [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Release of mature NEDD8 (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
UCHL3,SENP8:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Transfer of NEDD8 to AcM-UBE2F (Bos taurus)
AcM-UBE2F:NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Transfer of NEDD8 to AcM-UBE2M (Bos taurus)
AcM-UBE2M:NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
UCHL3, SENP8 cleave NEDD8 (Bos taurus)
UCHL3,SENP8:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
Transport of small molecules (Bos taurus)
Iron uptake and transport (Bos taurus)
NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
SKP1:FBXL5:CUL1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Bos taurus)
SKP1:FBXL5:CUL1:NEDD8 [cytosol] (Bos taurus)
NEDD8 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:P61282
Gene Names
NEDD8
Reference Genes
BioGPS Gene:286796 NEDD8
ENSEMBL:ENSBTAG00000038842
KEGG:bta:286796 NEDD8
Monarch:286796 NEDD8
NCBI Entrez Gene:286796 NEDD8
UCSC:P61282 NEDD8
Reference Transcript
RefSeq:NM_174764.3 NEDD8
Participates
as an output of
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)
Release of mature NEDD8 (Bos taurus)
as an input of
NEDD8-UBA3:NAE1 binds a second NEDD8 (Bos taurus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Bos taurus)
NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Bos taurus)
as a component of
UCHL3,SENP8:NEDD8 [cytosol] (Bos taurus)
NEDD8-UBA3:NAE1:NEDD8 [cytosol] (Bos taurus)
SKP1:FBXL5:CUL1:NEDD8 [cytosol] (Bos taurus)
as a member of
NEDD8,UBD [cytosol] (Bos taurus)
Other forms of this molecule
NEDD8 [nucleoplasm]
NEDD8 [nucleoplasm]
NEDD8 [cytosol]
NEDD8 [cytosol]
NEDD8 [cytosol]
NEDD8 [cytosol]
NEDD8 [cytosol]
Inferred From
NEDD8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_777189.1
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