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FANCB [nucleoplasm]
Stable Identifier
R-BTA-419528
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
FANCB, G3X787
Locations in the PathwayBrowser
Expand all
DNA Repair (Bos taurus)
Fanconi Anemia Pathway (Bos taurus)
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
DNA nucleases bind monoubiquitinated ID2 complex (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
DNA nucleases unhook the interstrand crosslink (ICL) (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
FA core complex assembles at DNA interstrand crosslinks (ICLs) (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
FANCD2 deubiquitination by USP1:WDR48 (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
Monoubiquitination of FANCD2:FANCI (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
POLN binds ICL-DNA (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
The complex of ATR and ATRIP is recruited to ICL-DNA (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
Translesion synthesis across unhooked ICL by POLN (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCB [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:G3X787
Gene Names
FANCB
Reference Genes
BioGPS Gene:616549 FANCB
ENSEMBL:ENSBTAG00000016433.3
ENSEMBL:ENSBTAG00000016433.4 FANCB
KEGG Gene (Bos taurus):616549 FANCB
Monarch:616549 FANCB
NCBI Gene:616549 FANCB
Reference Transcript
RefSeq:XM_010822208.2 FANCB
RefSeq:XM_010800601.2 FANCB
Other Identifiers
GO:0005634
GO:0006281
GO:0006310
GO:0036297
GO:0043226
GO:0043240
GO:1905168
GO:1990414
GO:2000042
Participates
as a component of
FA core complex [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
as an input of
FA core complex assembles at DNA interstrand crosslinks (ICLs) (Bos taurus)
Other forms of this molecule
FANCB [cytosol]
Inferred From
FANCB [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_010820510.1
,
XP_010798903.1
OpenTargets
ENSG00000181544
Ensembl
ENSBTAP00000021852
,
ENSBTAP00000057749
,
ENSBTAT00000021852
,
ENSBTAT00000082853
,
ENSBTAG00000016433
VGNC
28853
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