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FANCC [nucleoplasm]
Stable Identifier
R-BTA-419530
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
FANCC, A5PJJ8
Locations in the PathwayBrowser
Expand all
DNA Repair (Bos taurus)
Fanconi Anemia Pathway (Bos taurus)
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
DNA nucleases bind monoubiquitinated ID2 complex (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
DNA nucleases unhook the interstrand crosslink (ICL) (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
FA core complex assembles at DNA interstrand crosslinks (ICLs) (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
FANCD2 deubiquitination by USP1:WDR48 (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
Monoubiquitination of FANCD2:FANCI (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
POLN binds ICL-DNA (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
The complex of ATR and ATRIP is recruited to ICL-DNA (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Bos taurus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex:ICL-DNA [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
Translesion synthesis across unhooked ICL by POLN (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
FA core complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FANCC [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:A5PJJ8
Gene Names
FANCC
Reference Genes
ENSEMBL:ENSBTAG00000017195.6
ENSEMBL:ENSBTAG00000017195.7 FANCC
Other Identifiers
281762
Participates
as a component of
FA core complex [nucleoplasm] (Bos taurus)
p-FA Core Complex [nucleoplasm] (Bos taurus)
FA Core Complex [nucleoplasm] (Bos taurus)
as an input of
FA core complex assembles at DNA interstrand crosslinks (ICLs) (Bos taurus)
Other forms of this molecule
FANCC [cytosol]
Inferred From
FANCC [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000158169
Ensembl
ENSBTAT00000022853
,
ENSBTAG00000017195
,
ENSBTAP00000022853
VGNC
28854
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