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AR [nucleoplasm]
Stable Identifier
R-BTA-446174
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
AR, F1N2B6
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
ATP hydrolysis by HSP90 (Bos taurus)
HSP90 complexes [nucleoplasm] (Bos taurus)
HSP90:ATP:PTGES3:FKBP52:AR:Androgens [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
SHR:SH [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
HSP90:ATP:PTGES3:FKBP52:AR:Androgens [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Nuclear Receptor transcription pathway (Bos taurus)
Formation of NR-MED1 Coactivator Complex (Bos taurus)
NR [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
NR-MED1 Coactivator Complex [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
Formation of NR-NCOR Corepressor Complex (Bos taurus)
NR [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
NR-NCOR CoRepressor Complex [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
Transcriptional regulation by RUNX2 (Bos taurus)
RUNX2 regulates bone development (Bos taurus)
RUNX2 regulates osteoblast differentiation (Bos taurus)
Activated AR binds RUNX2 (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
RUNX2:AR:androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Deubiquitination (Bos taurus)
Ub-specific processing proteases (Bos taurus)
USP12, USP26 deubiquitinate AR (Bos taurus)
USP12:WDR48:WDR20,USP26:AR [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
SUMOylation (Bos taurus)
SUMO E3 ligases SUMOylate target proteins (Bos taurus)
SUMOylation of intracellular receptors (Bos taurus)
PIAS1,2-1 SUMOylates AR with SUMO1 (Bos taurus)
AR [nucleoplasm] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PKNs (Bos taurus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Bos taurus)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
PKN1 stimulates association of AR with NCOA2 (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:NCOA2 [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Bos taurus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
AR [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1N2B6
Gene Names
AR
Reference Genes
BioGPS Gene:280675 AR
ENSEMBL:ENSBTAG00000022255.4
ENSEMBL:ENSBTAG00000022255.5 AR
KEGG Gene (Bos taurus):280675 AR
Monarch:280675 AR
NCBI Gene:280675 AR
Reference Transcript
RefSeq:NM_001244127.1 AR
Other Identifiers
GO:0003677
GO:0003700
GO:0004879
GO:0005496
GO:0005634
GO:0006351
GO:0006355
GO:0008270
GO:0008289
GO:0008584
GO:0022414
GO:0023052
GO:0030518
GO:0030521
GO:0034056
GO:0043226
GO:0043565
GO:0045944
GO:0046872
GO:0048856
GO:0060089
GO:0140110
Participates
as a component of
USP12:WDR48:WDR20,USP26:AR [nucleoplasm] (Bos taurus)
AR:androgens [nucleoplasm] (Bos taurus)
as an input of
PIAS1,2-1 SUMOylates AR with SUMO1 (Bos taurus)
as a member of
NR [nucleoplasm] (Bos taurus)
Other forms of this molecule
AR [nucleoplasm]
AR [nucleoplasm]
AR [cytosol]
Inferred From
AR [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001231056.1
OpenTargets
ENSG00000169083
Ensembl
ENSBTAT00000030067
,
ENSBTAG00000022255
,
ENSBTAP00000030053
VGNC
26053
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