Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TAK1 complex [cytosol]
Stable Identifier
R-BTA-446878
Type
Complex
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAK1 is activated within the TAK1 complex (Bos taurus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAK1 phosphorylates MKK6 (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Interleukin-17 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Innate Immune System (Bos taurus)
Alpha-protein kinase 1 signaling pathway (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
C-type lectin receptors (CLRs) (Bos taurus)
CLEC7A (Dectin-1) signaling (Bos taurus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated NF-kB activation (Bos taurus)
Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Phosphorylation of IKK-beta by TAK1 (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Bos taurus)
NOD1/2 Signaling Pathway (Bos taurus)
TAK1 is activated (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAK1 phosphorylates MKK6 (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Bos taurus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Activation of TAK1 complex bound to activated TLR4 complex (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
TNF signaling (Bos taurus)
TNFR1-induced NF-kappa-B signaling pathway (Bos taurus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MAP3K7 [cytosol]
(Bos taurus)
TAB1 [cytosol]
(Bos taurus)
TAB2,TAB3 [cytosol]
(Bos taurus)
Participates
as an input of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Bos taurus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Bos taurus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Bos taurus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
as a component of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
Inferred From
TAB1:TAB2,TAB3:TAK1 [cytosol]
(Homo sapiens)
TAK1 complex [cytosol]
(Homo sapiens)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
