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IL5RA [plasma membrane]
Stable Identifier
R-BTA-450072
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
IL5RA, F1MH16
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-2 family signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits SHIP (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Bos taurus)
14-3-3 zeta binding allows recruitment of PI3K (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Activation of STAT5a/b by JAK2 (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
IL3RB is phosphorylated on Ser-585 (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits SHIP (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin-5 receptor alpha subunit binds Interleukin-5 (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
JAK2 is phosphorylated, activated (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
SHP1 and SHP2 bind the common beta chain (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
STAT5 is recruited by JAK2 (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
The receptor is activated (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Tyrosine kinases phosphorylate the receptor (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
p-S585-IL3RB binds 14-3-3 proteins (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
p-STAT5 dissociates from the receptor complex (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Bos taurus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Bos taurus)
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
IL5RA [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MH16
Gene Names
IL5RA
Reference Genes
ENSEMBL:ENSBTAG00000000273.6
Other Identifiers
615848
GO:0004896
GO:0005515
GO:0005886
GO:0009897
GO:0016020
GO:0019221
GO:0019955
GO:0023052
GO:0043235
GO:0060089
Participates
as an input of
Interleukin-5 receptor alpha subunit binds Interleukin-5 (Bos taurus)
as a component of
IL5 homodimer:IL5RA [plasma membrane] (Bos taurus)
Inferred From
IL5RA [plasma membrane]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000091181
Ensembl
ENSBTAT00000000339
,
ENSBTAP00000000339
,
ENSBTAG00000000273
VGNC
30165
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