Reactome | H2B [nucleoplasm]

H2B [nucleoplasm]

Stable Identifier

R-BTA-4568623

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

AcK6-HIST1H2BC, Q32S29

Locations in the PathwayBrowser

Expand all

Chromatin organization (Bos taurus)

- Chromatin modifying enzymes (Bos taurus)
  - HATs acetylate histones (Bos taurus)
    - EP300 acetylates histone H2A, H2B, H3, H4 (Bos taurus)
      - AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Bos taurus)
        
        H2B [nucleoplasm] (Bos taurus)
  - HDACs deacetylate histones (Bos taurus)
    - HDAC1:2-containing complex deacetylate histones (Bos taurus)
      - Acetylated core histone octamer [nucleoplasm] (Bos taurus)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Bos taurus)
        
        H2B [nucleoplasm] (Bos taurus)
    - HDAC3 containing complexes deacetylate histone (Bos taurus)
      - Acetylated core histone octamer [nucleoplasm] (Bos taurus)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Bos taurus)
        
        H2B [nucleoplasm] (Bos taurus)
    - HDAC8 deacetylates histones (Bos taurus)
      - Acetylated core histone octamer [nucleoplasm] (Bos taurus)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Bos taurus)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Bos taurus)
        
        H2B [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:Q32S29

Gene Names

H2B

Reference Genes

BioGPS Gene:519934 H2B

ENSEMBL:ENSBTAG00000051545

KEGG Gene (Bos taurus):519934 H2B

Monarch:519934 H2B

NCBI Gene:519934 H2B

Reference Transcript

RefSeq:NM_001114854.1 H2B

Other Identifiers

107131385

519934

GO:0000786

GO:0003674

GO:0003677

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0006334

GO:0008150

GO:0022607

GO:0032991

GO:0043226

GO:0046982

GO:0051276

GO:0065003

Participant Of

hasCandidate

AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm]

Other forms of this molecule

H2B [nucleoplasm]

Inferred From

AcK6-HIST1H2BC [nucleoplasm] (Homo sapiens)

AcK(6,13,16,21)-HIST1H2BC [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-acetyl-L-lysine at 6 (in Homo sapiens)

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_001108326.1

Target Pathogen

5b354852be737e166372ec68

Ensembl

ENSBTAP00000049501, ENSBTAG00000051545, ENSBTAT00000048984

Cite Us!