Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
YWHAB [cytosol]
Stable Identifier
R-BTA-48888
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
YWHAB, A0A140T894
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G2/M Checkpoints (Bos taurus)
G2/M DNA damage checkpoint (Bos taurus)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Bos taurus)
Association of p-S216-CDC25C with 14-3-3 proteins (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
FOXO-mediated transcription (Bos taurus)
Regulation of localization of FOXO transcription factors (Bos taurus)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Bos taurus)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Bos taurus)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
DDIT4 binds 14-3-3 dimer (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
DDIT4:14-3-3 dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
DDIT4:14-3-3 dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Rap1 signalling (Bos taurus)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Bos taurus)
14-3-3 beta, zeta [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Bos taurus)
14-3-3 beta, zeta [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Rap1 signal termination by Rap1GAPs (Bos taurus)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Bos taurus)
14-3-3 beta, zeta [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Metabolism of RNA (Bos taurus)
Regulation of mRNA stability by proteins that bind AU-rich elements (Bos taurus)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Bos taurus)
p-S54,92,203-BRF1 binds 14-3-3 (Bos taurus)
Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S92,203-BRF1 binds 14-3-3 (Bos taurus)
Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Bos taurus)
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Bos taurus)
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Intrinsic Pathway for Apoptosis (Bos taurus)
Activation of BH3-only proteins (Bos taurus)
Activation of BAD and translocation to mitochondria (Bos taurus)
Activation of BAD by calcineurin (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Sequestration of BAD protein by 14-3-3 (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
Dissociation of RAS:RAF complex (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Negative regulation of MAPK pathway (Bos taurus)
PEBP1 binds activated RAF1 (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
PP2A dephosphorylates RAF1 (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
PP5 dephosphorylates RAF1 S338 (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAF activation (Bos taurus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Inactive RAFs bind YWHAB (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
PP2A dephosphorylates KSR1 (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
PP2A dephosphorylates inactive RAFs (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Phosphorylation of RAF (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Raf dimer inhibitors bind RAF heterodimers (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
YWHAB dimer dissociates from KSR1:MARK3 (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
YWHAB dimer dissociates from dephosphorylated RAF (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
MTOR signalling (Bos taurus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
YWHAB [cytosol] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
mTORC1-mediated signalling (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Signaling by Hippo (Bos taurus)
YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-YAP1:YWHAB [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
Frs2-mediated activation (Bos taurus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Bos taurus)
BRAF dimer complex [cytosol] (Bos taurus)
B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)
BRAF dimer complex [cytosol] (Bos taurus)
B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:B-Raf complex [endosome membrane] (Bos taurus)
BRAF dimer complex [cytosol] (Bos taurus)
B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Dissociation of phosphorylated MAP2Ks and MAPKs (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Bos taurus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PKNs (Bos taurus)
Association of p-S216-CDC25C with 14-3-3 proteins (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A140T894
Gene Names
YWHAB
Reference Genes
BioGPS Gene:286863 YWHAB
ENSEMBL:ENSBTAG00000016846.3
ENSEMBL:ENSBTAG00000016846.4 YWHAB
KEGG Gene (Bos taurus):286863 YWHAB
Monarch:286863 YWHAB
NCBI Gene:286863 YWHAB
Reference Transcript
RefSeq:NM_174794.2 YWHAB
Other Identifiers
286863
GO:0004860
GO:0005737
GO:0005829
GO:0006605
GO:0006886
GO:0019899
GO:0019904
GO:0023052
GO:0035308
GO:0036211
GO:0042802
GO:0042826
GO:0045744
GO:0048471
GO:0050815
GO:0051219
GO:0051220
GO:0098772
Participates
as an input of
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Bos taurus)
p-S54,92,203-BRF1 binds 14-3-3 (Bos taurus)
p-S92,203-BRF1 binds 14-3-3 (Bos taurus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
as a component of
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Bos taurus)
Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Bos taurus)
Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
B-Raf complex [cytosol] (Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
as a member of
14-3-3 beta, zeta [cytosol] (Bos taurus)
Inferred From
YWHAB [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_777219.2
OpenTargets
ENSG00000166913
Ensembl
ENSBTAT00000022411
,
ENSBTAP00000022411
,
ENSBTAG00000016846
VGNC
37044
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text