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VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane]
Stable Identifier
R-BTA-5218760
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
CRK binds BCAR1 and or PXN (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
DOCK180:ELMO binds CRK (Bos taurus)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
PXN binds p-6Y,S732-PTK2 (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
phospho-p-6Y,S732-PTK2 [cytosol]
(Bos taurus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]
(Bos taurus)
Participates
as a component of
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Bos taurus)
Inferred From
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane]
(Homo sapiens)
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