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NR1H4 [nucleoplasm]
Stable Identifier
R-BTA-5340228
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
NR1H4, F1MTT1
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Nuclear Receptor transcription pathway (Bos taurus)
Formation of NR-MED1 Coactivator Complex (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
NR-MED1 Coactivator Complex [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Formation of NR-NCOR Corepressor Complex (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
NR-NCOR CoRepressor Complex [nucleoplasm] (Bos taurus)
NR [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP7A1 7-hydroxylates CHOL (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
CYP7B1 7-hydroxylates 25OH-CHOL (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Recycling of bile acids and salts (Bos taurus)
NR1H4 binds DCA, CDCA, LCHA (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Synthesis of bile acids and bile salts (Bos taurus)
CYP7B1 7-hydroxylates 25OH-CHOL (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Bos taurus)
27-hydroxycholesterol is 7alpha-hydroxylated (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
CYP7A1 7-hydroxylates CHOL (Bos taurus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
SUMOylation (Bos taurus)
SUMO E3 ligases SUMOylate target proteins (Bos taurus)
SUMOylation of intracellular receptors (Bos taurus)
SUMOylation of NR1H4 with SUMO1 (Bos taurus)
NR1H4:chenodeoxycholate [nucleoplasm] (Bos taurus)
NR1H4 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MTT1
Gene Names
NR1H4
Reference Genes
ENSEMBL:ENSBTAG00000013596.5
ENSEMBL:ENSBTAG00000013596.6 NR1H4
Other Identifiers
540528
GO:0000122
GO:0000791
GO:0000977
GO:0000978
GO:0000981
GO:0001221
GO:0001228
GO:0001678
GO:0002376
GO:0003677
GO:0003700
GO:0004879
GO:0005634
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006520
GO:0006629
GO:0006954
GO:0007043
GO:0007219
GO:0008206
GO:0008270
GO:0008289
GO:0010804
GO:0010903
GO:0010988
GO:0012501
GO:0023052
GO:0030154
GO:0030522
GO:0032052
GO:0032689
GO:0032692
GO:0032703
GO:0032715
GO:0032720
GO:0032740
GO:0034162
GO:0034255
GO:0034330
GO:0035356
GO:0035774
GO:0038181
GO:0038183
GO:0038185
GO:0042593
GO:0042632
GO:0042742
GO:0043066
GO:0043124
GO:0043226
GO:0043235
GO:0043565
GO:0045893
GO:0045944
GO:0046628
GO:0046872
GO:0046965
GO:0048856
GO:0050728
GO:0055089
GO:0060089
GO:0061178
GO:0070328
GO:0071222
GO:0071398
GO:0071417
GO:0071638
GO:0071941
GO:0098542
GO:0140110
GO:1902122
GO:1903413
GO:1904179
GO:1905695
GO:2000213
GO:2001250
Participates
as a component of
NR1H4:chenodeoxycholate [nucleoplasm] (Bos taurus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Bos taurus)
as an input of
NR1H4 binds DCA, CDCA, LCHA (Bos taurus)
as a member of
NR [nucleoplasm] (Bos taurus)
Other forms of this molecule
NR1H4 [nucleoplasm]
Inferred From
NR1H4 [nucleoplasm]
(Homo sapiens)
NR1H4-1 [nucleoplasm]
(Homo sapiens)
NR1H4-3 [nucleoplasm]
(Homo sapiens)
NR1H4-2 [nucleoplasm]
(Homo sapiens)
NR1H4-4 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000012504
Ensembl
ENSBTAT00000018079
,
ENSBTAP00000018079
,
ENSBTAG00000013596
VGNC
32232
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