TSFM binds TUFM displacing GDP

Stable Identifier
R-BTA-5432536
Type
Reaction
Species
Bos taurus
Compartment
General
SVG |   | PPTX  | SBGN
TSFM binds TUFM displacing GDP

TSFM (EF-Ts, EF-TsMt) acts as a GTP exchange factor to regenerate TUFM:GTP from TUFM:GDP. In the first step of the reaction TSFM binds TUFM:GDP and displaces GDP, yielding a TSFM:TUFM complex (Cai et al. 2000).

Literature References
PubMed ID Title Journal Year
10801827 Interaction of mitochondrial elongation factor Tu with aminoacyl-tRNA and elongation factor Ts

Cai, YC, Bullard, JM, Thompson, NL, Spremulli, LL

J. Biol. Chem. 2000
11045624 Interaction of mammalian mitochondrial elongation factor EF-Tu with guanine nucleotides

Cai, YC, Bullard, JM, Thompson, NL, Spremulli, LL

Protein Sci. 2000
Participants
Orthologous Events
Authored
Reviewed
Created