Reactome | GNA12 [plasma membrane]

GNA12 [plasma membrane]

Stable Identifier

R-BTA-55355

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

GNA12, E1BIL1

Locations in the PathwayBrowser

Expand all

Hemostasis (Bos taurus)

- Platelet activation, signaling and aggregation (Bos taurus)
  - Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
    - Thrombin-activated PARs activate G12/13 (Bos taurus)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Bos taurus)
        
        G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
        
        G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
        
        GNA12 [plasma membrane] (Bos taurus)
      - Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Bos taurus)
        
        G-protein G12/G13 (inactive) [plasma membrane] (Bos taurus)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Bos taurus)
        
        G-protein alpha (12):GDP [plasma membrane] (Bos taurus)
        
        GNA12 [plasma membrane] (Bos taurus)
    - Thrombin-activated PARs:G12/13 (active) dissociate (Bos taurus)
      - G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
        
        G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
        
        GNA12 [plasma membrane] (Bos taurus)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Bos taurus)
        
        G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
        
        G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
        
        GNA12 [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BIL1

Gene Names

GNA12

Reference Genes

BioGPS Gene:515159 GNA12

ENSEMBL:ENSBTAG00000017871.6

KEGG Gene (Bos taurus):515159 GNA12

Monarch:515159 GNA12

NCBI Gene:515159 GNA12

Reference Transcript

RefSeq:NM_001192401.1 GNA12

Other Identifiers

515159

GO:0000166

GO:0001664

GO:0001701

GO:0003013

GO:0003824

GO:0003924

GO:0005525

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007188

GO:0007266

GO:0008217

GO:0008360

GO:0010762

GO:0016020

GO:0016328

GO:0016787

GO:0019001

GO:0019888

GO:0023052

GO:0030154

GO:0030163

GO:0031526

GO:0031683

GO:0031752

GO:0032006

GO:0032434

GO:0035556

GO:0042733

GO:0043005

GO:0043025

GO:0048856

GO:0048870

GO:0051721

GO:0098772

Participates

as a component of

Inferred From

GNA12 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001179330.1

OpenTargets

ENSG00000146535

Ensembl

ENSBTAG00000058903, ENSBTAT00000023757, ENSBTAP00000023757

VGNC

29445

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