IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated

Stable Identifier
R-BTA-6786096
Type
Reaction [BlackBoxEvent]
Species
Bos taurus
Compartment
Locations in the PathwayBrowser
Summation

This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
non-membrane spanning protein tyrosine kinase activity of IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane]
Physical Entity
Activity
Inferred From