Reactome | NABP2 [nucleoplasm]

NABP2 [nucleoplasm]

Stable Identifier

R-BTA-6814916

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

NABP2, A6QLK2

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Bos taurus)

- RNA Polymerase II Transcription (Bos taurus)
  - RNA polymerase II transcribes snRNA genes (Bos taurus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Bos taurus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
    - Integrator complex processes the 3' end of snRNA (Bos taurus)
      - Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Bos taurus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Bos taurus)
      - Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Bos taurus)
        
        Integrator [nucleoplasm] (Bos taurus)
        
        NABP1,2 [nucleoplasm] (Bos taurus)
        
        NABP2 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:A6QLK2

Gene Names

NABP2

Reference Genes

BioGPS Gene:533842 NABP2

ENSEMBL:ENSBTAG00000002798

ENSEMBL:ENSBTAG00000002798.5 NABP2

KEGG Gene (Bos taurus):533842 NABP2

Monarch:533842 NABP2

NCBI Gene:533842 NABP2

Reference Transcript

Other Identifiers

533842

GO:0003676

Participates

as a member of

NABP1,2 [nucleoplasm] (Bos taurus)

Inferred From

NABP2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001094621.1, XP_005206696.1, XP_005206698.1, XP_005206697.1

OpenTargets

ENSG00000139579

Ensembl

ENSBTAG00000002798, ENSBTAT00000044279, ENSBTAP00000041786

VGNC

31860