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RFC4 [nucleoplasm]
Stable Identifier
R-BTA-68429
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
RFC4, A0A3Q1M1J3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G2/M Checkpoints (Bos taurus)
Activation of ATR in response to replication stress (Bos taurus)
Recruitment of Rad17-RFC complex to DNA (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Rad17-RFC complex bound to DNA [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Bos taurus)
Rad17-RFC complex bound to DNA [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Bos taurus)
Rad17-RFC complex bound to DNA [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
G2/M DNA damage checkpoint (Bos taurus)
ATR phosphorylates TP53 (Bos taurus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
S Phase (Bos taurus)
Synthesis of DNA (Bos taurus)
DNA strand elongation (Bos taurus)
Lagging Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Loading of PCNA - Sliding Clamp Formation (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC binding displaces Pol Alpha (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC dissociates after sliding clamp formation (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Leading Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Loading of PCNA - Sliding Clamp Formation (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC binding displaces Pol Alpha (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC dissociates after sliding clamp formation (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Chromosome Maintenance (Bos taurus)
Telomere Maintenance (Bos taurus)
Extension of Telomeres (Bos taurus)
Telomere C-strand (Lagging Strand) Synthesis (Bos taurus)
Polymerase switching on the C-strand of the telomere (Bos taurus)
Formation of the CTF18-RFC(7s) complex (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
RFC,(CFT18-RFC) [nucleoplasm] (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
RFC,(CFT18-RFC) [nucleoplasm] (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
RFC,(CFT18-RFC) [nucleoplasm] (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC,(CFT18-RFC) [nucleoplasm] (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
RFC,(CFT18-RFC) [nucleoplasm] (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC,(CFT18-RFC) [nucleoplasm] (Bos taurus)
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
DNA Repair (Bos taurus)
Base Excision Repair (Bos taurus)
Resolution of Abasic Sites (AP sites) (Bos taurus)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Bos taurus)
PCNA-Dependent Long Patch Base Excision Repair (Bos taurus)
LIG1 binds APEX1 and PCNA at SSB (Bos taurus)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
LIG1 bound to APEX1 and PCNA ligates SSB (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Bos taurus)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLD,POLE-mediated DNA strand displacement synthesis (Bos taurus)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
DNA Damage Bypass (Bos taurus)
Recognition of DNA damage by PCNA-containing replication complex (Bos taurus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
USP1:WDR48 binds monoUb:K164-PCNA (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Bos taurus)
Termination of translesion DNA synthesis (Bos taurus)
POLD,POLE binds deISGylated PCNA after TLS (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
TRIM25 binds monoUb:164-PCNA (Bos taurus)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Bos taurus)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
USP43 binds ISG:K164,ISG:K168-PCNA (Bos taurus)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
USP43 deISGylates ISG:K164,ISG:K168-PCNA (Bos taurus)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Translesion Synthesis by POLH (Bos taurus)
Elongation by POLH (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Insertion of correct bases opposite the lesion by POLH (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
SPRTN binds monoUb:K164-PCNA associated with POLH (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Bos taurus)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Bos taurus)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Translesion synthesis by POLI (Bos taurus)
POLI incorporates dNMP opposite to damaged DNA base (Bos taurus)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLZ elongates POLI-incorporated dNMP (Bos taurus)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Translesion synthesis by POLK (Bos taurus)
POLK and POLZ cooperate in elongation of mispaired primer termini (Bos taurus)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLK incorporates dNMP opposite to damaged DNA base (Bos taurus)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Translesion synthesis by REV1 (Bos taurus)
POLZ extends translesion synthesis (Bos taurus)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1 binds AP-dsDNA (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1 inserts dCMP opposite to AP sites in DNA (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Bos taurus)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
DNA Double-Strand Break Repair (Bos taurus)
Homology Directed Repair (Bos taurus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Bos taurus)
HDR through Homologous Recombination (HRR) (Bos taurus)
D-loop extension by DNA polymerases (Bos taurus)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
HDR through Single Strand Annealing (SSA) (Bos taurus)
Association of RAD51 with RAD52:DNA double-strand break ends (Bos taurus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Association of RAD52 with the RPA complex at resected DNA DSBs (Bos taurus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
ERCC1:XPF cleaves flaps generated by SSA (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD52 promotes single strand annealing at resected DNA DSBs (Bos taurus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Processing of DNA double-strand break ends (Bos taurus)
ATR activation at DNA DSBs (Bos taurus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
ATR phosphorylates RPA2 (Bos taurus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Nucleotide Excision Repair (Bos taurus)
Global Genome Nucleotide Excision Repair (GG-NER) (Bos taurus)
Dual Incision in GG-NER (Bos taurus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Bos taurus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Gap-filling DNA repair synthesis and ligation in GG-NER (Bos taurus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Bos taurus)
Dual incision in TC-NER (Bos taurus)
3' incision by ERCC5 (XPG) in TC-NER (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Bos taurus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
Synthesis of DNA (Bos taurus)
DNA strand elongation (Bos taurus)
Lagging Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Loading of PCNA - Sliding Clamp Formation (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC binding displaces Pol Alpha (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC dissociates after sliding clamp formation (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Leading Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Loading of PCNA - Sliding Clamp Formation (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC binding displaces Pol Alpha (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC dissociates after sliding clamp formation (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
Regulation of TP53 Activity (Bos taurus)
Regulation of TP53 Activity through Phosphorylation (Bos taurus)
ATR phosphorylates TP53 (Bos taurus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
RFC4 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1M1J3
Gene Names
RFC4
Reference Genes
ENSEMBL:ENSBTAG00000014727.6
Participates
as an input of
Formation of the CTF18-RFC(7s) complex (Bos taurus)
as a component of
CTF18-RFC(7s) complex [nucleoplasm] (Bos taurus)
RFC Heteropentamer [nucleoplasm] (Bos taurus)
RAD17:RFC [nucleoplasm] (Bos taurus)
Inferred From
RFC4 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000163918
VGNC
33888
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